Nothing Special   »   [go: up one dir, main page]

SG11201706367WA - Systems and methods for assessing biological samples - Google Patents

Systems and methods for assessing biological samples

Info

Publication number
SG11201706367WA
SG11201706367WA SG11201706367WA SG11201706367WA SG11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA
Authority
SG
Singapore
Prior art keywords
systems
methods
biological samples
assessing biological
assessing
Prior art date
Application number
SG11201706367WA
Inventor
Mingsong Chen
Kuan Moon Boo
Tiong Han Toh
Mauro Aguanno
Soo Yong Lau
Huei Steven Yeo
Wei Fuh Teo
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55404853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201706367W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201706367WA publication Critical patent/SG11201706367WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0332Cuvette constructions with temperature control
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6402Atomic fluorescence; Laser induced fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • G02B21/244Devices for focusing using image analysis techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/168Specific optical properties, e.g. reflective coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
SG11201706367WA 2015-02-06 2016-02-05 Systems and methods for assessing biological samples SG11201706367WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562112910P 2015-02-06 2015-02-06
PCT/US2016/016886 WO2016127128A1 (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Publications (1)

Publication Number Publication Date
SG11201706367WA true SG11201706367WA (en) 2017-09-28

Family

ID=55404853

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201811725SA SG10201811725SA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples
SG11201706367WA SG11201706367WA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples
SG10202103903UA SG10202103903UA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201811725SA SG10201811725SA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202103903UA SG10202103903UA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Country Status (10)

Country Link
US (3) US20160230210A1 (en)
EP (3) EP3254085B1 (en)
JP (3) JP6985144B2 (en)
KR (2) KR102494654B1 (en)
CN (2) CN107548453B (en)
BR (1) BR112017016937B1 (en)
ES (1) ES2943159T3 (en)
RU (1) RU2708542C2 (en)
SG (3) SG10201811725SA (en)
WO (1) WO2016127128A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015009264A (en) 2013-01-18 2016-03-31 Biomeme Inc Analytic device.
JP6985144B2 (en) 2015-02-06 2021-12-22 ライフ テクノロジーズ コーポレーション Systems and methods for evaluating biological samples
US10324041B2 (en) * 2016-12-21 2019-06-18 Abbott Japan Co., Ltd. Optical imaging system using lateral illumination for digital assays
CN206348514U (en) * 2016-12-23 2017-07-21 卡尔蔡司医疗技术股份公司 Surgical operation microscope and the device for making it switch between multiple-working mode
US11047854B2 (en) 2017-02-06 2021-06-29 Abbott Japan Llc Methods for reducing noise in signal-generating digital assays
JP7293236B2 (en) 2017-09-15 2023-06-19 バイオミーム インコーポレイテッド Method and system for automated sample processing
CN112326652B (en) * 2017-09-20 2021-09-03 深圳市真迈生物科技有限公司 Imaging method, device and system for controlling sequence determination reaction
EP3724352A4 (en) * 2017-12-15 2021-09-01 Biomeme, Inc. Portable devices and methods for analyzing samples
NL2020636B1 (en) * 2017-12-28 2019-07-08 Illumina Inc Light energy fluorescence excitation
KR102133633B1 (en) * 2018-04-17 2020-07-13 (주)로고스바이오시스템스 A device for real-time detecting nucleic acids amplification products
KR102113217B1 (en) * 2018-07-23 2020-05-21 광주과학기술원 Target protein tracing equipment using in laser inducing X-ray
CN109324024A (en) * 2018-09-17 2019-02-12 中国人民解放军陆军军医大学第三附属医院(野战外科研究所) Small integrated immunofluorescence analysis device
US10883925B2 (en) * 2018-09-24 2021-01-05 Hf Scientific, Inc. Spectrophotometer for use in explosive atmospheres
USD921222S1 (en) * 2019-01-04 2021-06-01 Meso Scale Technologies, Llc. Instrument
USD1016325S1 (en) 2019-01-04 2024-02-27 Meso Scale Technologies, Llc. Instrument
WO2020191193A1 (en) 2019-03-21 2020-09-24 Biomeme, Inc. Multi-function analytic devices
CN110057808A (en) 2019-05-27 2019-07-26 中国人民解放军军事科学院军事医学研究院 Sample swivel mount and Raman spectrum detector
KR102220353B1 (en) * 2019-06-10 2021-02-25 한국전자기술연구원 Fluorescence reader system measuring by time control using image sensor
KR102400907B1 (en) * 2019-06-30 2022-05-24 주식회사 진시스템 Multiplex pcr apparatus
CN110672550B (en) * 2019-09-10 2021-11-19 中国科学院上海技术物理研究所 Image spectrum analyzer for important biological resources in micro-area
CN112904013B (en) * 2019-12-04 2023-06-20 中国科学院大连化学物理研究所 High-energy ultraviolet cross-linking instrument for biological sample
WO2021246745A1 (en) * 2020-06-03 2021-12-09 Seegene, Inc. Optical signal detection device for detecting multiple optical signals for multiple target analytes from sample
CA3186950A1 (en) 2020-07-23 2022-01-27 Scott Benson Compositions, systems and methods for biological analysis involving energy transfer dye conjugates and analytes comprising the same
WO2022020729A2 (en) 2020-07-23 2022-01-27 Life Technologies Corporation Systems and methods for biological analysis
KR102559634B1 (en) * 2020-08-26 2023-07-26 한국전자통신연구원 Apparatus and method for pcr diagnosis based on multiwavelength light source
US12054770B2 (en) 2020-08-26 2024-08-06 Electronics And Telecommunications Research Institute Apparatus and method for PCR diagnosis based on multi-wavelength light source
KR102380565B1 (en) * 2020-09-18 2022-03-30 (주)얼라인드제네틱스 Sample inspection device for detecting fluorescence in the sample
CN116457099A (en) 2020-09-18 2023-07-18 生米公司 Portable device and method for analyzing a sample
CN114563379A (en) * 2020-11-27 2022-05-31 纬创资通股份有限公司 Detection device and detection method
CN113092424B (en) * 2021-03-18 2023-02-10 上海医本医疗器械有限公司 High-flux biochip analyzer
CN113122614B (en) * 2021-04-15 2021-11-16 珠海市尚维高科生物技术有限公司 Fluorescent quantitative PCR processing method and system
WO2023055340A1 (en) * 2021-09-28 2023-04-06 Hewlett-Packard Development Company, L.P. Apparatuses with immobilized capture agents in a reaction region of a chamber
CN113777768A (en) * 2021-10-13 2021-12-10 大连理工大学 Microscopic imaging and optical sensing Internet of things system based on 3D printing and manufacturing
KR102506675B1 (en) * 2022-03-14 2023-03-08 서강대학교산학협력단 Internet of things-based portable multiplex digital polymerase chain reaction sysyem

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02293651A (en) * 1989-05-08 1990-12-04 Hitachi Ltd Spectrochemical analysis of radioactive liquid
DE4013586C2 (en) * 1990-04-27 1994-08-18 Suzuki Motor Co Device for the detection of immunological agglutination
JPH05149789A (en) * 1991-11-26 1993-06-15 Sumitomo Metal Ind Ltd Method and device for measuring raman-spectroscopy
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
JPH07318427A (en) 1994-05-30 1995-12-08 Shimadzu Corp Fluorescence analyzer
US5932872A (en) * 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
US5672881A (en) * 1994-09-14 1997-09-30 Glyko, Inc. Charge-coupled device imaging apparatus
DE19616151A1 (en) * 1996-04-23 1997-10-30 Boehringer Mannheim Gmbh Video system for evaluating analytical test elements
US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US5754291A (en) 1996-09-19 1998-05-19 Molecular Dynamics, Inc. Micro-imaging system
JPH10170239A (en) * 1996-10-08 1998-06-26 Matsushita Electric Ind Co Ltd Three-dimensional shape measuring device
WO1998048262A1 (en) * 1997-04-23 1998-10-29 Packard Instrument Company, Inc. Measurement of fluorescence
JPH11119309A (en) 1997-10-09 1999-04-30 Minolta Co Ltd Camera
WO1999060381A1 (en) 1998-05-16 1999-11-25 The Perkin-Elmer Corporation Instrument for monitoring polymerase chain reaction of dna
US6236456B1 (en) * 1998-08-18 2001-05-22 Molecular Devices Corporation Optical system for a scanning fluorometer
JP3761054B2 (en) 1998-10-09 2006-03-29 富士写真フイルム株式会社 Image information reader
JP3585753B2 (en) * 1998-12-15 2004-11-04 富士写真フイルム株式会社 Shooting system
DE19919092A1 (en) * 1999-04-27 2000-11-02 Zeiss Carl Jena Gmbh Arrangement for the optical evaluation of an array of objects
US7423750B2 (en) * 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
US20050279949A1 (en) 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
JP4846152B2 (en) * 1999-11-12 2011-12-28 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー Fluorescence measuring instrument with low heat source
US6775567B2 (en) * 2000-02-25 2004-08-10 Xenogen Corporation Imaging apparatus
US7027932B2 (en) * 2001-03-21 2006-04-11 Olympus Optical Co., Ltd. Biochemical examination method
US7635588B2 (en) 2001-11-29 2009-12-22 Applied Biosystems, Llc Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
JP3723145B2 (en) * 2002-03-28 2005-12-07 富士写真フイルム株式会社 Imaging apparatus, image processing apparatus, and imaging system
US9157860B2 (en) * 2002-05-16 2015-10-13 Applied Biosystems, Llc Achromatic lens array
EP1511991B1 (en) * 2002-05-17 2015-05-06 Life Technologies Corporation Optical instrument includung excitation source
EP1506390B1 (en) * 2002-05-17 2011-12-14 Life Technologies Corporation Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
US7148043B2 (en) * 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
EP1630586B1 (en) * 2003-06-02 2015-01-07 Nikon Corporation Microscope device
JP4474663B2 (en) 2003-08-27 2010-06-09 努 升島 Video microscope equipment
EP2752874A1 (en) * 2004-06-07 2014-07-09 Fluidigm Corporation Method and apparatus for imaging a device under temperature control
WO2006055521A2 (en) 2004-11-16 2006-05-26 Helicos Biosciences Corporation Tirf single molecule analysis and method of sequencing nucleic acids
US7417803B2 (en) * 2004-11-18 2008-08-26 Cognex Technology And Investment Corporation Focusing mechanism for a vision detector
US7324202B2 (en) * 2004-12-07 2008-01-29 Novx Systems Inc. Optical system
US7491502B2 (en) 2004-12-17 2009-02-17 The General Hospital Corporation In vivo flow cytometry system and method
US7264794B2 (en) * 2004-12-17 2007-09-04 The General Hospital Methods of in vivo cytometry
EP1681556B1 (en) 2005-01-18 2007-04-11 Roche Diagnostics GmbH Imaging fluorescence signals using telecentricity
WO2006092317A1 (en) * 2005-03-03 2006-09-08 Ese Embedded System Engineering Gmbh Fluorescence meter
JP4800655B2 (en) * 2005-04-01 2011-10-26 オリンパス株式会社 Light measuring device
JP2007046904A (en) * 2005-08-05 2007-02-22 Sanyo Electric Co Ltd Reaction detector
US20070037135A1 (en) * 2005-08-08 2007-02-15 Barnes Russell H System and method for the identification and quantification of a biological sample suspended in a liquid
DE102005054184B4 (en) 2005-11-14 2020-10-29 Carl Zeiss Microscopy Gmbh Multispectral lighting device and measuring method
EP1962084A1 (en) * 2007-02-21 2008-08-27 Roche Diagnostics GmbH Apparatus for emitting and detecting beams of light
DE102007020610A1 (en) 2007-04-30 2008-11-20 Thomas Dr. Ruckstuhl Container and method for detecting fluorescence
WO2009033021A2 (en) * 2007-09-05 2009-03-12 Chroma Technology Corporation Light source with wavelength converting phosphor
CN101393313B (en) * 2007-09-21 2010-06-02 鸿富锦精密工业(深圳)有限公司 Color wheel
CN101419156B (en) * 2007-10-23 2012-12-05 深圳迈瑞生物医疗电子股份有限公司 Spectrophotometric detecting method and apparatus , and detecting system
US8791427B2 (en) * 2007-12-26 2014-07-29 Olympus Corporation Biological-specimen observation apparatus
JP2009254256A (en) * 2008-04-15 2009-11-05 Konica Minolta Medical & Graphic Inc Inspection apparatus
EP2148187A1 (en) * 2008-07-25 2010-01-27 Roche Diagnostics GmbH Stimulation and optical display system for fluorescence detection
JP2010142570A (en) * 2008-12-22 2010-07-01 Hoya Corp Optical system of endoscope
JP5715068B2 (en) * 2009-01-30 2015-05-07 マイクロニクス, インコーポレイテッド Portable high gain fluorescence detection system
CN102341710B (en) 2009-04-15 2015-04-01 比奥卡尔齐什股份有限公司 Optical detection system for monitoring rtpcr reaction
CN201837588U (en) * 2009-09-09 2011-05-18 海利克斯公司 Optical system for multiple reactions
CN201622245U (en) * 2009-12-02 2010-11-03 西安工业大学 Combined testing device for laser damage threshold of film and optical element
JP2011158419A (en) * 2010-02-03 2011-08-18 Sony Corp Optical detector
US8436321B2 (en) 2010-05-21 2013-05-07 Li-Cor, Inc. Optical background suppression systems and methods for fluorescence imaging
JP2012022206A (en) 2010-07-15 2012-02-02 Olympus Corp Microscopic observation system
CN102243107A (en) * 2011-04-20 2011-11-16 张强 High-sensitivity up-conversion single photon detection system
SG11201401911XA (en) 2011-09-30 2014-08-28 Life Technologies Corp Systems and methods for biological analysis
SG11201401919TA (en) * 2011-09-30 2014-10-30 Life Technologies Corp Optical systems and methods for biological analysis
US10928321B2 (en) 2012-03-09 2021-02-23 Ubiquitome Limited Portable device for detecting molecule(s)
SG11201406040SA (en) * 2012-03-16 2014-11-27 Life Technologies Corp Systems and methods for assessing of biological samples
AU2013231910A1 (en) 2012-03-16 2014-10-30 Life Technologies Corporation Systems and methods for biological analysis
GB201205607D0 (en) 2012-03-29 2012-05-16 Ltd Technopath Distrib A fluorescence microtitre plate reader
WO2013146364A1 (en) * 2012-03-29 2013-10-03 三洋電機株式会社 Sample holding carrier, and fluorescence detection system and fluorescence detection device that use same
CN104143156A (en) 2013-05-06 2014-11-12 上海科斗电子科技有限公司 Intelligent entity trading system
JP6269239B2 (en) * 2013-05-28 2018-01-31 株式会社ニコン Structured illumination device and structured illumination microscope device
JP6985144B2 (en) 2015-02-06 2021-12-22 ライフ テクノロジーズ コーポレーション Systems and methods for evaluating biological samples

Also Published As

Publication number Publication date
US20160230210A1 (en) 2016-08-11
JP6985144B2 (en) 2021-12-22
EP3254085B1 (en) 2020-04-29
CN107548453B (en) 2021-03-23
US11920191B2 (en) 2024-03-05
CN107548453A (en) 2018-01-05
KR20170125838A (en) 2017-11-15
EP3719481A2 (en) 2020-10-07
BR112017016937B1 (en) 2021-02-17
JP2022031290A (en) 2022-02-18
SG10202103903UA (en) 2021-06-29
JP7389095B2 (en) 2023-11-29
US20210214771A1 (en) 2021-07-15
EP4220139A3 (en) 2023-08-09
RU2708542C2 (en) 2019-12-09
CN113049553B (en) 2024-08-20
KR20230022450A (en) 2023-02-15
ES2943159T3 (en) 2023-06-09
RU2017131221A3 (en) 2019-05-29
EP3719481B1 (en) 2023-03-29
EP3254085A1 (en) 2017-12-13
WO2016127128A1 (en) 2016-08-11
JP2018506039A (en) 2018-03-01
KR102494654B1 (en) 2023-01-31
BR112017016937A2 (en) 2018-04-03
US20240309441A1 (en) 2024-09-19
JP2023099589A (en) 2023-07-13
RU2017131221A (en) 2019-03-06
EP3719481A3 (en) 2020-11-25
SG10201811725SA (en) 2019-02-27
CN113049553A (en) 2021-06-29
EP4220139A2 (en) 2023-08-02

Similar Documents

Publication Publication Date Title
SG11201706367WA (en) Systems and methods for assessing biological samples
HK1249179A1 (en) Devices and methods for sample analysis
SG10202001197UA (en) Systems and methods for biological analysis
HK1250182A1 (en) Systems and methods for analyzing nucleic acid
IL259736A (en) Methods and systems for nucleic acid analysis
ZA201901986B (en) Devices and methods for sample analysis
ZA201706572B (en) Devices and methods for sample analysis
ZA201901985B (en) Devices and methods for sample analysis
HK1247380A1 (en) Image analysis systems and related methods
IL250282A0 (en) High-throughput sample processing systems and methods of use
HK1221012A1 (en) Laboratory sample distribution system and laboratory automation system
EP3391058A4 (en) Systems and methods for automated analysis
HK1222744A1 (en) Methods and systems for data analysis and compression
SG11201701855RA (en) Systems and methods for liveness analysis
SG11201706332RA (en) Methods and systems for biological instrument calibration
EP3149464A4 (en) System and method for electronic biological sample analysis
EP2971141A4 (en) Systems and methods for biological analysis
GB202117492D0 (en) iKnife - cell line identification and analysis
EP3709001C0 (en) Systems and methods for determining sample osmolarity
SG11201800647SA (en) Biological condition determination device and biological condition determination method
GB2556835B (en) Sample preparation system and cartridge
IL251134B (en) System and method for following and conducting laboratory procedures
GB201717399D0 (en) Proteogenomic analysis system and methods
HK1247370A1 (en) Tissue sample analysis technique
HK1245885A1 (en) Methods and devices for quantitating blood samples