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SG11201704386VA - Anticancer compositions - Google Patents

Anticancer compositions

Info

Publication number
SG11201704386VA
SG11201704386VA SG11201704386VA SG11201704386VA SG11201704386VA SG 11201704386V A SG11201704386V A SG 11201704386VA SG 11201704386V A SG11201704386V A SG 11201704386VA SG 11201704386V A SG11201704386V A SG 11201704386VA SG 11201704386V A SG11201704386V A SG 11201704386VA
Authority
SG
Singapore
Prior art keywords
anticancer compositions
anticancer
compositions
Prior art date
Application number
SG11201704386VA
Inventor
Geert Verreck
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52006907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201704386V(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of SG11201704386VA publication Critical patent/SG11201704386VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201704386VA 2014-12-05 2015-12-03 Anticancer compositions SG11201704386VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14196605 2014-12-05
PCT/US2015/063671 WO2016090105A1 (en) 2014-12-05 2015-12-03 Anticancer compositions

Publications (1)

Publication Number Publication Date
SG11201704386VA true SG11201704386VA (en) 2017-06-29

Family

ID=52006907

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201704386VA SG11201704386VA (en) 2014-12-05 2015-12-03 Anticancer compositions

Country Status (34)

Country Link
US (3) US10285948B2 (en)
EP (2) EP3226843B1 (en)
JP (1) JP6830892B2 (en)
KR (1) KR102387089B1 (en)
CN (1) CN106999432A (en)
AR (1) AR102925A1 (en)
AU (1) AU2015358497B2 (en)
CA (1) CA2969675C (en)
CL (1) CL2017001373A1 (en)
CO (1) CO2017005574A2 (en)
CR (1) CR20170218A (en)
CY (1) CY1124504T1 (en)
DK (1) DK3226843T3 (en)
EA (1) EA201791251A1 (en)
ES (1) ES2883187T3 (en)
HR (1) HRP20211140T1 (en)
HU (1) HUE054935T2 (en)
IL (1) IL252325A0 (en)
LT (1) LT3226843T (en)
MA (1) MA41111B1 (en)
MD (1) MD3226843T2 (en)
MX (1) MX2017007206A (en)
MY (1) MY192931A (en)
NI (1) NI201700068A (en)
PH (1) PH12017500979A1 (en)
PL (1) PL3226843T3 (en)
PT (1) PT3226843T (en)
RS (1) RS62421B1 (en)
SG (1) SG11201704386VA (en)
SI (1) SI3226843T1 (en)
SM (1) SMT202100454T1 (en)
TW (1) TWI709403B (en)
UA (1) UA123538C2 (en)
WO (1) WO2016090105A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201912719TA (en) 2012-09-26 2020-02-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
SG11201704386VA (en) 2014-12-05 2017-06-29 Aragon Pharmaceuticals Inc Anticancer compositions
KR20240096623A (en) 2017-10-16 2024-06-26 아라곤 파마슈티컬스, 인코포레이티드 Anti-androgens for the treatment of non-metastatic castration-resistant
WO2020144649A1 (en) 2019-01-10 2020-07-16 Aragon Pharmaceuticals, Inc. Pharmaceutical composition comprising enzalutamide dispersed in apple sauce
US20210115517A1 (en) 2019-01-30 2021-04-22 Janssen Pharmaceutica Nv Methods of treating prostate cancer based on molecular subtypes
JP2022523094A (en) 2019-01-30 2022-04-21 アラゴン ファーマシューティカルズ,インコーポレイテッド Antiandrogens for the treatment of metastatic castration-sensitive prostate cancer
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
CA3160121A1 (en) 2019-11-04 2021-05-14 Aragon Pharmaceuticals, Inc. Androgen receptor inhibitors for the treatment of non-metastatic castration-resistant prostate cancer in subjects with severe hepatic impairment
WO2021245285A1 (en) 2020-06-05 2021-12-09 Janssen Pharmaceutica Nv Methods of treating prostate cancer based on molecular subtypes
TW202228794A (en) 2020-09-04 2022-08-01 美商艾瑞岡醫藥公司 Methods for treating prostate cancer
WO2022195407A1 (en) 2021-03-19 2022-09-22 Aragon Pharmaceuticals, Inc. Methods for treating prostate cancer
WO2023152611A1 (en) 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer
WO2023209555A1 (en) 2022-04-26 2023-11-02 Aragon Pharmaceuticals, Inc. Approved drug products and methods for treating prostate cancer
TW202444354A (en) 2023-03-16 2024-11-16 瑞士商拜耳保健消費品股份有限公司 Androgen receptor antagonists for the treatment of patients with biochemical recurrence of hormone sensitive prostate cancer

Family Cites Families (36)

* Cited by examiner, † Cited by third party
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ATE186913T1 (en) 1992-03-31 1999-12-15 Btg Int Ltd 17-SUBSTITUTED STEROIDS USABLE IN TREATING CANCER
DE69837903T2 (en) 1997-08-11 2008-02-14 Pfizer Products Inc., Groton Solid pharmaceutical dispersions with increased bioavailability
US20030068374A1 (en) 2000-02-21 2003-04-10 Shigeru Kamei Sustained release preparations of physiologically active compound hardly soluble in water and production process and use of the same
CN1503662A (en) 2001-02-27 2004-06-09 Pharmaceutical preparation
DE60211139T2 (en) 2001-04-02 2007-03-01 Astrazeneca Ab SOLID MEDICAMENT COMPOSITION CONTAINING 4'-CYANO-TRIFLUORO-3- (4-FLUORO-PHENYLSULPHONYL) -2-HYDROXY-2-METHYLPROPIONO- M TOLUIDIDE AND PVP
CZ20033457A3 (en) 2001-06-22 2004-09-15 Pfizer Products Inc. Pharmaceutical composition comprising medicaments of low solubility and/or medicaments sensitive to acid and neutralized acid polymers
SE0103424D0 (en) 2001-10-15 2001-10-15 Astrazeneca Ab Pharmaceutical formulation
JP2005523260A (en) 2002-02-01 2005-08-04 ファイザー・プロダクツ・インク Method for producing homogeneous spray-dried solid amorphous drug dispersion using pressure nozzle
JPWO2003077827A1 (en) 2002-03-19 2005-07-14 日本新薬株式会社 Method for producing pharmaceutical solid dispersion
CA2549572A1 (en) 2003-12-15 2005-06-23 Council Of Scientific & Industrial Research Taste masked pharmaceutical compositions comprising bitter drug and ph sensitive polymer
SI2004181T1 (en) 2006-03-27 2016-07-29 The Regents Of The University Of California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
EP2414356B1 (en) * 2009-04-03 2015-09-02 F.Hoffmann-La Roche Ag Propane-i-sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide compositions and uses thereof
MX355915B (en) 2010-02-16 2018-05-04 Aragon Pharmaceuticals Inc Androgen receptor modulators and uses thereof.
CN102525876B (en) * 2010-12-15 2014-03-12 西安力邦医药科技有限责任公司 Aspirin solid dispersion, as well as preparation method, pharmaceutical composition and use thereof
AU2012271403C1 (en) 2011-06-15 2018-02-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
US20150037407A1 (en) 2012-03-21 2015-02-05 Emphascience, Inc. Method to improve the safety of handling of high potency drugs in solid dosage forms without changing their efficacy
WO2013152342A1 (en) 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Anti-cancer mtor inhibitor and anti-androgen combination
LT2858985T (en) * 2012-06-07 2018-09-25 Aragon Pharmaceuticals, Inc. Crystalline forms of an androgen receptor modulator
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
US20150218198A1 (en) 2012-08-24 2015-08-06 Dow Global Technologies Llc Novel hydroxyalkyl methyl cellulose acetate succinates
US9977033B2 (en) 2012-09-11 2018-05-22 The Board Of Regents Of The University Of Texas System Methods for assessing cancer recurrence
EP3971167A1 (en) * 2012-09-11 2022-03-23 Medivation Prostate Therapeutics LLC Formulations of enzalutamide
SG10201912719TA (en) * 2012-09-26 2020-02-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
JOP20200097A1 (en) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc Androgen receptor modulator and uses thereof
PE20151335A1 (en) 2013-01-22 2015-09-18 Hoffmann La Roche PHARMACEUTICAL COMPOSITION WITH IMPROVED BIODAVAILABILITY
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WO2014167428A2 (en) 2013-04-10 2014-10-16 Shilpa Medicare Limited Amorphous 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-n-methylbenzamide
AU2014306698A1 (en) 2013-08-12 2016-01-28 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
WO2015116696A1 (en) * 2014-01-28 2015-08-06 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
AU2015215000B2 (en) * 2014-02-05 2017-10-19 Lek Pharmaceuticals D.D. Solid pharmaceutical compositions of androgen receptor antagonists
LT3102595T (en) 2014-02-06 2019-01-25 F. Hoffmann-La Roche Ag Interleukin-2 fusion proteins and uses thereof
TWI765410B (en) 2014-08-08 2022-05-21 日商中外製藥股份有限公司 Use of amorphous body of tetracyclic compound
SI3226842T1 (en) 2014-12-05 2021-04-30 Aragon Pharmaceuticals, Inc. Anticancer compositions
MA41107A (en) 2014-12-05 2017-10-10 Aragon Pharmaceuticals Inc ANTI-CANCER COMPOSITIONS
SG11201704386VA (en) 2014-12-05 2017-06-29 Aragon Pharmaceuticals Inc Anticancer compositions
CN109219437A (en) * 2016-06-03 2019-01-15 阿拉贡药品公司 Anti-cancer composition

Also Published As

Publication number Publication date
SMT202100454T1 (en) 2021-09-14
MX2017007206A (en) 2018-01-30
CY1124504T1 (en) 2022-07-22
SI3226843T1 (en) 2021-11-30
KR102387089B1 (en) 2022-04-14
AU2015358497B2 (en) 2021-04-29
CN106999432A (en) 2017-08-01
LT3226843T (en) 2021-08-10
MY192931A (en) 2022-09-15
AU2015358497A1 (en) 2017-06-08
WO2016090105A1 (en) 2016-06-09
US20210308060A1 (en) 2021-10-07
BR112017011726A2 (en) 2017-12-26
US11224575B2 (en) 2022-01-18
HRP20211140T1 (en) 2021-10-15
CA2969675C (en) 2023-06-06
EP3226843A1 (en) 2017-10-11
PH12017500979A1 (en) 2017-11-27
EA201791251A1 (en) 2017-11-30
UA123538C2 (en) 2021-04-21
TWI709403B (en) 2020-11-11
PL3226843T3 (en) 2021-12-13
EP3925598B1 (en) 2025-02-12
CR20170218A (en) 2017-08-30
US20170360713A1 (en) 2017-12-21
RS62421B1 (en) 2021-10-29
AR102925A1 (en) 2017-04-05
DK3226843T3 (en) 2021-08-16
PT3226843T (en) 2021-07-07
EP3925598A1 (en) 2021-12-22
TW201636019A (en) 2016-10-16
ES2883187T3 (en) 2021-12-07
IL252325A0 (en) 2017-07-31
CA2969675A1 (en) 2016-06-09
HUE054935T2 (en) 2021-10-28
US11911511B2 (en) 2024-02-27
JP2017536407A (en) 2017-12-07
NI201700068A (en) 2017-09-11
KR20170086658A (en) 2017-07-26
JP6830892B2 (en) 2021-02-17
CL2017001373A1 (en) 2018-01-05
EP3226843B1 (en) 2021-05-26
US10285948B2 (en) 2019-05-14
US20190209477A1 (en) 2019-07-11
MA41111B1 (en) 2021-09-30
CO2017005574A2 (en) 2017-09-29
MD3226843T2 (en) 2021-10-31

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