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SG11201604501TA - Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer - Google Patents

Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer

Info

Publication number
SG11201604501TA
SG11201604501TA SG11201604501TA SG11201604501TA SG11201604501TA SG 11201604501T A SG11201604501T A SG 11201604501TA SG 11201604501T A SG11201604501T A SG 11201604501TA SG 11201604501T A SG11201604501T A SG 11201604501TA SG 11201604501T A SG11201604501T A SG 11201604501TA
Authority
SG
Singapore
Prior art keywords
estrogen receptor
treatment
breast cancer
locally advanced
positive breast
Prior art date
Application number
SG11201604501TA
Inventor
Maneval Edna Chow
Bao Tran H Truong
Isan Chen
Jeffrey H Hager
Debashish F Roychowdhury
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11201604501TA publication Critical patent/SG11201604501TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/4161,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201604501TA 2013-12-06 2014-12-05 Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer SG11201604501TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361913167P 2013-12-06 2013-12-06
US201461981672P 2014-04-18 2014-04-18
PCT/IB2014/002679 WO2015082990A1 (en) 2013-12-06 2014-12-05 Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer

Publications (1)

Publication Number Publication Date
SG11201604501TA true SG11201604501TA (en) 2016-07-28

Family

ID=52347358

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201604501TA SG11201604501TA (en) 2013-12-06 2014-12-05 Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer

Country Status (12)

Country Link
US (2) US9675586B2 (en)
EP (1) EP3089747A1 (en)
JP (1) JP2016540767A (en)
KR (1) KR20160085915A (en)
CN (1) CN105916501A (en)
AU (1) AU2014358850A1 (en)
CA (1) CA2932106A1 (en)
HK (1) HK1223557A1 (en)
IL (1) IL245758A0 (en)
MX (1) MX2016007282A (en)
SG (1) SG11201604501TA (en)
WO (1) WO2015082990A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
GB201216017D0 (en) 2012-09-07 2012-10-24 Cancer Rec Tech Ltd Inhibitor compounds
SG10201912719TA (en) 2012-09-26 2020-02-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
US9586952B2 (en) 2013-03-14 2017-03-07 Genentech, Inc. Polycyclic estrogen receptor modulators and uses thereof
CA2912853A1 (en) 2013-06-19 2014-12-24 Seragon Pharmaceuticals, Inc. Estrogen receptor modulator and uses thereof
BR112015030595A2 (en) 2013-06-19 2017-07-25 Seragon Pharmaceuticals Inc azetidine estrogen receptor modulators and uses thereof
JP2017509631A (en) 2014-03-13 2017-04-06 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Methods and compositions for modulating estrogen receptor mutants
US20180173846A1 (en) * 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
KR20170040251A (en) 2014-08-11 2017-04-12 에프. 호프만-라 로슈 아게 Crystalline forms of an estrogen receptor modulator
PT3233852T (en) 2014-12-18 2020-09-10 Hoffmann La Roche Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof
US9845291B2 (en) 2014-12-18 2017-12-19 Genentech, Inc. Estrogen receptor modulators and uses thereof
EP3303326B1 (en) 2015-05-26 2020-12-16 H. Hoffnabb-La Roche Ag Heterocyclic estrogen receptor modulators and uses thereof
WO2017060326A1 (en) 2015-10-07 2017-04-13 F. Hoffmann-La Roche Ag Process for the preparation of (e)-3-(4-((e)-2-(2-chloro-4-fluorophenyl)-1-(1h-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid
JP6592197B2 (en) 2015-11-12 2019-10-16 浙江海正薬業股▲ふん▼有限公司Zhejiang Hisun Pharmaceutical CO.,LTD. Acrylic acid derivatives, process for preparation and use thereof as pharmaceuticals
BR112018070161A2 (en) 2016-04-01 2019-02-12 Zeno Royalties & Milestones, LLC estrogen receptor modulators
US20180002344A1 (en) 2016-06-16 2018-01-04 Genentech, Inc. Heteroaryl estrogen receptor modulators and uses thereof
GB201709840D0 (en) 2017-06-20 2017-08-02 Inst Of Cancer Research: Royal Cancer Hospital Methods and medical uses
CN110799183A (en) * 2017-06-20 2020-02-14 癌症研究所:皇家癌症医院 Method and medical use
SG11202003402QA (en) 2017-10-16 2020-05-28 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer
EP3498273A1 (en) * 2017-12-14 2019-06-19 Universität Wien Pharmaceutical composition for modulating the response of a gaba-a receptor
CA3098601A1 (en) * 2018-05-02 2019-11-07 Estetra Sprl Treatment of advanced estrogen receptor positive breast cancer
CA3098203A1 (en) 2018-06-21 2019-12-26 F. Hoffmann-La Roche Ag Tartrate salt of 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and crystal forms thereof
ES2924738T3 (en) 2018-09-07 2022-10-10 Sanofi Sa Process for the preparation of 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo Methyl [7]annulene-2-carboxylate and a salt thereof
WO2020225375A1 (en) * 2019-05-09 2020-11-12 Sanofi 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid for use in metastatic or advanced breast cancer patients
US20220220107A1 (en) 2019-05-24 2022-07-14 Zhejiang Hisun Pharmaceutical Co., Ltd. Crystal forms of acrylic acid derivatives, preparation method therefor and use thereof
BR112022002138A2 (en) 2019-08-06 2022-04-19 Recurium Ip Holdings Llc Estrogen receptor modulators for treatment of mutants
WO2022140744A1 (en) 2020-12-23 2022-06-30 Recurium Ip Holdings, Llc Estrogen receptor modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2483736B (en) 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
PE20142461A1 (en) 2012-03-20 2015-02-05 Seragon Pharmaceuticals Inc ESTROGEN RECEPTOR MODULATORS AND THEIR USES
US9586952B2 (en) 2013-03-14 2017-03-07 Genentech, Inc. Polycyclic estrogen receptor modulators and uses thereof

Also Published As

Publication number Publication date
HK1223557A1 (en) 2017-08-04
JP2016540767A (en) 2016-12-28
WO2015082990A1 (en) 2015-06-11
CA2932106A1 (en) 2015-06-11
US9675586B2 (en) 2017-06-13
MX2016007282A (en) 2016-09-07
EP3089747A1 (en) 2016-11-09
IL245758A0 (en) 2016-07-31
CN105916501A (en) 2016-08-31
US10034860B2 (en) 2018-07-31
KR20160085915A (en) 2016-07-18
AU2014358850A1 (en) 2016-06-16
US20170239219A1 (en) 2017-08-24
WO2015082990A8 (en) 2016-07-21
AU2014358850A8 (en) 2016-08-04
US20150157606A1 (en) 2015-06-11

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