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SG11201503085VA - Perfusion culturing methods and uses thereof - Google Patents

Perfusion culturing methods and uses thereof

Info

Publication number
SG11201503085VA
SG11201503085VA SG11201503085VA SG11201503085VA SG11201503085VA SG 11201503085V A SG11201503085V A SG 11201503085VA SG 11201503085V A SG11201503085V A SG 11201503085VA SG 11201503085V A SG11201503085V A SG 11201503085VA SG 11201503085V A SG11201503085V A SG 11201503085VA
Authority
SG
Singapore
Prior art keywords
culturing methods
perfusion culturing
perfusion
methods
culturing
Prior art date
Application number
SG11201503085VA
Inventor
Jianguo Yang
Agata Villiger-Oberbek
Yang Yang
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG11201503085VA publication Critical patent/SG11201503085VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/50—Means for positioning or orientating the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201503085VA 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof SG11201503085VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261717486P 2012-10-23 2012-10-23
PCT/US2013/066410 WO2014066519A1 (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof

Publications (1)

Publication Number Publication Date
SG11201503085VA true SG11201503085VA (en) 2015-05-28

Family

ID=49546634

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201503085VA SG11201503085VA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof
SG10201901708SA SG10201901708SA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201901708SA SG10201901708SA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof

Country Status (9)

Country Link
US (1) US20140154726A1 (en)
EP (2) EP3747984A1 (en)
CN (2) CN104903436B (en)
AU (2) AU2013334602B2 (en)
CA (1) CA2889022A1 (en)
HK (1) HK1214292A1 (en)
MX (2) MX363702B (en)
SG (2) SG11201503085VA (en)
WO (1) WO2014066519A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10421949B2 (en) 2013-02-22 2019-09-24 Genzyme Corporation Microcarrier perfusion culturing methods and uses thereof
CN105209603A (en) 2013-02-22 2015-12-30 建新公司 Microcarrier perfusion culturing methods and uses thereof
AR095196A1 (en) 2013-03-15 2015-09-30 Regeneron Pharma SERUM FREE CELL CULTIVATION MEDIA
TWI743024B (en) * 2014-06-06 2021-10-21 美商健臻公司 Perfusion culturing methods and uses thereof
TW202246486A (en) 2014-06-09 2022-12-01 美商健臻公司 Seed train processes and uses thereof
CN107109322B (en) 2014-10-24 2021-04-06 建新公司 Integrated continuous separation of fluid streams from a sterilization process vessel
CA3225136A1 (en) 2014-12-22 2016-06-30 Genzyme Corporation Methods of culturing a mammalian cell
CN105385731B (en) * 2015-12-25 2018-10-30 上海莱士血液制品股份有限公司 A kind of perfusion cultural method of eight factors of expression recombination
KR20180047404A (en) * 2016-10-31 2018-05-10 삼성바이오에피스 주식회사 Process for reducing undesirable by-product in cell culture
WO2018178063A1 (en) * 2017-03-31 2018-10-04 Boehringer Ingelheim International Gmbh Perfusion medium
MA50911A (en) * 2017-11-13 2020-09-23 Amgen Inc PROTEIN PRODUCTS PRODUCTION PROCESSES

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1016538A3 (en) * 2004-02-20 2007-01-09 Cesco Bioengineering Co Ltd Apparatus and method for the preparation and application in cell culture.
US20080199958A1 (en) * 2005-06-15 2008-08-21 Amprotein Corporation Suspension Culture Vessels
WO2006138143A1 (en) * 2005-06-15 2006-12-28 Amprotein Corporation Suspension culture vessels
WO2008024769A2 (en) * 2006-08-21 2008-02-28 Raven Biotechnologies, Inc. Intensified perfusion production method
WO2009034186A2 (en) * 2007-09-13 2009-03-19 Helmholtz-Zentrum für Infektionsforschung GmbH Process for cell cultivation
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
CN101821378B (en) * 2008-06-16 2015-07-08 浙江金仪盛世生物工程有限公司 Bioreactors
WO2010120514A2 (en) 2009-03-31 2010-10-21 The Trustees Of The University Of Pennsylvania Antigen-binding proteins comprising recombinant protein scaffolds

Also Published As

Publication number Publication date
EP2912160B1 (en) 2020-07-29
MX2015005206A (en) 2016-08-03
CA2889022A1 (en) 2014-05-01
CN108192822A (en) 2018-06-22
EP2912160A1 (en) 2015-09-02
AU2013334602B2 (en) 2018-05-31
EP3747984A1 (en) 2020-12-09
MX363702B (en) 2019-03-29
CN104903436A (en) 2015-09-09
WO2014066519A1 (en) 2014-05-01
HK1214292A1 (en) 2016-07-22
US20140154726A1 (en) 2014-06-05
AU2018222985A1 (en) 2018-09-20
MX2019003638A (en) 2019-09-02
CN104903436B (en) 2018-03-30
SG10201901708SA (en) 2019-03-28
AU2013334602A1 (en) 2015-05-14

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