SG11201407880QA - Treatment of solid tumors using coenzyme q10 - Google Patents
Treatment of solid tumors using coenzyme q10Info
- Publication number
- SG11201407880QA SG11201407880QA SG11201407880QA SG11201407880QA SG11201407880QA SG 11201407880Q A SG11201407880Q A SG 11201407880QA SG 11201407880Q A SG11201407880Q A SG 11201407880QA SG 11201407880Q A SG11201407880Q A SG 11201407880QA SG 11201407880Q A SG11201407880Q A SG 11201407880QA
- Authority
- SG
- Singapore
- Prior art keywords
- lllll
- international
- llll
- coenzyme
- treatment
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 5 December 2013 (05.12.2013) WIPOIPCT (10) International Publication Number WO 2013/181639 A1 (51) International Patent Classification: A01N 35/00 (2006.01) A61K 9/10 (2006.01) A61K 9/19 (2006.01) (21) International Application Number: PCT/US2013/043785 (22) International Filing Date: 31 May 2013 (31.05.2013) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 61/654,245 1 June 2012 (01.06.2012) US (54) Title: TREATMENT OF SOLID TUMORS USING COENZYME Q10 FIGURE 3 A (71) Applicant: BERG PHARMA LLC [US/US]; 1845 Elm Hill Pike, Nashville, TN 37210 (US). (72) Inventors: NARAIN, Niven, Rajin; 73 Fresh Pond Park way, Cambridge, MA 02138 (US). MCCOOK, John, Patrick; 4913 Southern Hills Drive, Frisco, TX 75034 (US). SONG, Paul, Y.; 234 Alta Drive, Santa Monica, CA 90402 (US). MACIAS-PEREZ, Ines; 4549 Raccoon Trail, Hermitage, TN 37076 (US). (74) Agents: HANLEY, Elizabeth, A. et al.; McCarter & Eng lish, LLP, 265 Franklin Street, Boston, MA 02110 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, [Continued on next page] (57) Abstract: The invention provides methods and composi tions for treatment of a subject with solid a tumor comprising ad ministration of Coenzyme Q10 (CoQIO), particularly when the subject has failed least at one prior chemotherapeutic regimen. WO 2013/181639 A11 lllll llllllll II llllll III lllll lllll III III III lllll lllll lllll lllll lllll llll llll lllllll llll llll DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261654245P | 2012-06-01 | 2012-06-01 | |
| PCT/US2013/043785 WO2013181639A1 (en) | 2012-06-01 | 2013-05-31 | Treatment of solid tumors using coenzyme q10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201407880QA true SG11201407880QA (en) | 2014-12-30 |
Family
ID=49673946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201407880QA SG11201407880QA (en) | 2012-06-01 | 2013-05-31 | Treatment of solid tumors using coenzyme q10 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20140017317A1 (en) |
| EP (1) | EP2854528B8 (en) |
| JP (3) | JP6352905B2 (en) |
| KR (2) | KR20200118233A (en) |
| CN (1) | CN104507308A (en) |
| AU (2) | AU2013267166A1 (en) |
| BR (1) | BR112014029954A2 (en) |
| CA (2) | CA2875150C (en) |
| EA (1) | EA032345B1 (en) |
| ES (1) | ES2761449T3 (en) |
| HK (1) | HK1208995A1 (en) |
| IL (1) | IL236008B (en) |
| IN (1) | IN2014DN10734A (en) |
| MX (2) | MX369768B (en) |
| NZ (1) | NZ702369A (en) |
| SG (1) | SG11201407880QA (en) |
| WO (1) | WO2013181639A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1010908A2 (en) | 2009-05-11 | 2016-03-15 | Berg Biosystems Llc | methods for treating metabolic disorders using epimetabolic protractors, multi-dimensional intracellular molecules or environmental influencers. |
| WO2012138765A1 (en) | 2011-04-04 | 2012-10-11 | Berg Pharma Llc | Methods of treating central nervous system tumors |
| SG11201407880QA (en) * | 2012-06-01 | 2014-12-30 | Berg Llc | Treatment of solid tumors using coenzyme q10 |
| JP6731336B2 (en) | 2013-04-08 | 2020-07-29 | バーグ エルエルシー | Method of treating cancer using coenzyme Q10 combination therapy |
| CN105705162A (en) | 2013-09-04 | 2016-06-22 | 博格有限责任公司 | Methods of treatment of cancer by continuous infusion of coenzyme q10 |
| US9996463B2 (en) * | 2015-11-10 | 2018-06-12 | International Business Machines Corporation | Selection and placement of volumes in a storage system using stripes |
| US20170189350A1 (en) * | 2015-11-16 | 2017-07-06 | Berg Llc | Methods of treatment of temozolomide-resistant glioma using coenzyme q10 |
| US20170255565A1 (en) * | 2016-03-02 | 2017-09-07 | Intel Corporation | Method and apparatus for providing a contiguously addressable memory region by remapping an address space |
| WO2018005412A1 (en) * | 2016-06-28 | 2018-01-04 | Tien Yang Der | Chemoprotective/chemoactive nanodroplets and methods of use thereof |
| AU2018269377A1 (en) * | 2017-05-17 | 2019-12-19 | Berg Llc | Use of coenzyme Q10 formulations in the treatment and prevention of epidermolysis bullosa |
| AU2022400186A1 (en) * | 2021-12-01 | 2024-06-20 | Gambro Lundia Ab | New dialysis fluid |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5898031A (en) | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| US20070104688A1 (en) | 2003-02-13 | 2007-05-10 | City Of Hope | Small interfering RNA mediated transcriptional gene silencing in mammalian cells |
| WO2005048925A2 (en) * | 2003-11-14 | 2005-06-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating a neoplastic disease in a subject using inorganic selenium-containing compounds |
| JP5247031B2 (en) * | 2004-01-22 | 2013-07-24 | ユニバーシティー・オブ・マイアミ | Topical coenzyme Q10 formulation |
| EP2123266B1 (en) * | 2006-12-06 | 2014-01-15 | Kaneka Corporation | Cancer therapeutic agent and anti-carcinogenic agent |
| BRPI0809164B8 (en) | 2007-03-22 | 2023-02-28 | Berg Llc | COMPOSITION FOR TOPICAL ADMINISTRATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAID COMPOSITION |
| US7732491B2 (en) * | 2007-11-12 | 2010-06-08 | Bipar Sciences, Inc. | Treatment of breast cancer with a PARP inhibitor alone or in combination with anti-tumor agents |
| EP2229186A2 (en) | 2007-12-04 | 2010-09-22 | Alnylam Pharmaceuticals Inc. | Carbohydrate conjugates as delivery agents for oligonucleotides |
| US8247435B2 (en) * | 2009-02-19 | 2012-08-21 | Thornthwaite Jerry T | Formulations for treating human and animal diseases |
| BRPI1010908A2 (en) * | 2009-05-11 | 2016-03-15 | Berg Biosystems Llc | methods for treating metabolic disorders using epimetabolic protractors, multi-dimensional intracellular molecules or environmental influencers. |
| GB0913193D0 (en) | 2009-07-29 | 2009-09-02 | Johnson Matthey Plc | Deoxygenation process |
| SG183508A1 (en) * | 2010-03-12 | 2012-10-30 | Berg Pharma Llc | Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof |
| EP2720680B1 (en) | 2011-06-17 | 2020-02-12 | Berg LLC | Inhalable pharmaceutical compositions |
| SG11201407880QA (en) | 2012-06-01 | 2014-12-30 | Berg Llc | Treatment of solid tumors using coenzyme q10 |
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2013
- 2013-05-31 SG SG11201407880QA patent/SG11201407880QA/en unknown
- 2013-05-31 JP JP2015515272A patent/JP6352905B2/en active Active
- 2013-05-31 MX MX2014014492A patent/MX369768B/en active IP Right Grant
- 2013-05-31 ES ES13797642T patent/ES2761449T3/en active Active
- 2013-05-31 US US13/907,726 patent/US20140017317A1/en not_active Abandoned
- 2013-05-31 IN IN10734DEN2014 patent/IN2014DN10734A/en unknown
- 2013-05-31 CN CN201380040105.3A patent/CN104507308A/en active Pending
- 2013-05-31 CA CA2875150A patent/CA2875150C/en active Active
- 2013-05-31 EA EA201492187A patent/EA032345B1/en not_active IP Right Cessation
- 2013-05-31 KR KR1020207028370A patent/KR20200118233A/en not_active Application Discontinuation
- 2013-05-31 AU AU2013267166A patent/AU2013267166A1/en not_active Abandoned
- 2013-05-31 BR BR112014029954A patent/BR112014029954A2/en not_active IP Right Cessation
- 2013-05-31 CA CA3090268A patent/CA3090268A1/en not_active Abandoned
- 2013-05-31 NZ NZ702369A patent/NZ702369A/en not_active IP Right Cessation
- 2013-05-31 EP EP13797642.9A patent/EP2854528B8/en active Active
- 2013-05-31 KR KR1020147037100A patent/KR102163948B1/en active IP Right Grant
- 2013-05-31 WO PCT/US2013/043785 patent/WO2013181639A1/en active Application Filing
-
2014
- 2014-11-27 MX MX2019013776A patent/MX2019013776A/en unknown
- 2014-11-30 IL IL236008A patent/IL236008B/en active IP Right Grant
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2015
- 2015-10-05 HK HK15109710.3A patent/HK1208995A1/en unknown
-
2016
- 2016-10-10 US US15/289,770 patent/US20170216223A1/en not_active Abandoned
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2017
- 2017-04-19 AU AU2017202567A patent/AU2017202567B2/en not_active Ceased
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2018
- 2018-06-07 JP JP2018109093A patent/JP2018168164A/en not_active Withdrawn
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2020
- 2020-07-29 JP JP2020127877A patent/JP7225167B2/en active Active
-
2021
- 2021-05-17 US US17/321,699 patent/US20220096399A1/en active Pending
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