SG11201401608PA - Method for inhibition of deubiquitinating activity - Google Patents
Method for inhibition of deubiquitinating activityInfo
- Publication number
- SG11201401608PA SG11201401608PA SG11201401608PA SG11201401608PA SG11201401608PA SG 11201401608P A SG11201401608P A SG 11201401608PA SG 11201401608P A SG11201401608P A SG 11201401608PA SG 11201401608P A SG11201401608P A SG 11201401608PA SG 11201401608P A SG11201401608P A SG 11201401608PA
- Authority
- SG
- Singapore
- Prior art keywords
- inhibition
- deubiquitinating activity
- deubiquitinating
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1100776 | 2011-10-19 | ||
SE1200303 | 2012-05-16 | ||
PCT/SE2012/000158 WO2013058691A1 (en) | 2011-10-19 | 2012-10-15 | Method for inhibition of deubiquitinating activity |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201401608PA true SG11201401608PA (en) | 2014-07-30 |
Family
ID=48141165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201401608PA SG11201401608PA (en) | 2011-10-19 | 2012-10-15 | Method for inhibition of deubiquitinating activity |
Country Status (22)
Country | Link |
---|---|
US (1) | US9221761B2 (en) |
EP (1) | EP2780326B1 (en) |
JP (1) | JP6165748B2 (en) |
KR (1) | KR102022575B1 (en) |
CN (1) | CN104271557B (en) |
AU (1) | AU2012326682B2 (en) |
BR (1) | BR112014009365B1 (en) |
CA (1) | CA2852518C (en) |
CL (1) | CL2014000998A1 (en) |
DK (1) | DK2780326T3 (en) |
EA (1) | EA026409B1 (en) |
ES (1) | ES2713484T3 (en) |
HK (1) | HK1203194A1 (en) |
HU (1) | HUE041816T2 (en) |
IL (1) | IL232118A (en) |
MX (1) | MX345467B (en) |
MY (1) | MY169330A (en) |
PL (1) | PL2780326T3 (en) |
PT (1) | PT2780326T (en) |
SG (1) | SG11201401608PA (en) |
WO (1) | WO2013058691A1 (en) |
ZA (1) | ZA201403302B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2780326T (en) * | 2011-10-19 | 2019-03-04 | Vivolux Ab | Method for inhibition of deubiquitinating activity |
WO2014105952A2 (en) | 2012-12-28 | 2014-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of the usp1/uaf1 deubiquitinase complex and uses thereof |
EP3164506A4 (en) * | 2014-07-01 | 2018-02-28 | Mayo Foundation for Medical Education and Research | Methods and materials for identifying and treating mammals resistant to proteasome inhibitor treatments |
GB201416754D0 (en) * | 2014-09-23 | 2014-11-05 | Mission Therapeutics Ltd | Novel compounds |
SG11201706542TA (en) * | 2015-03-30 | 2017-10-30 | Mission Therapeutics Ltd | 1-cyano-pyrrolidine compounds as usp30 inhibitors |
CN106146542A (en) * | 2015-04-23 | 2016-11-23 | 北京大学 | Curcumin boronic acid derivatives, its preparation method and application |
GB201522768D0 (en) * | 2015-12-23 | 2016-02-03 | Mission Therapeutics Ltd | Novel compounds |
US10416163B2 (en) * | 2016-02-26 | 2019-09-17 | Regents Of The University Of Minnesota | Method and treatment of recurring endometrial cancer with an inhibitor of USP14 |
WO2018140907A1 (en) * | 2017-01-30 | 2018-08-02 | Up Therapeutics Inc. | Novel spiro and cyclic bis-benzylidine proteasome inhibitor for the treatment of cancer, diabetes and neurological disorders |
CN111956804B (en) * | 2020-07-21 | 2022-01-07 | 广州医科大学 | Novel use of inhibitors of OTUB1 |
CN114959036A (en) * | 2022-06-07 | 2022-08-30 | 北京大学 | Application of RPN11 marker in detection of myeloma and its disease risk, prognosis analysis and treatment medicine |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1242379A1 (en) * | 1999-12-03 | 2002-09-25 | Emory University | Curcumin analogues for treating cancer |
US20060229239A9 (en) * | 2002-03-08 | 2006-10-12 | Mamoru Shoji | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis |
US20070010488A1 (en) * | 2005-04-13 | 2007-01-11 | Khairia Youssef | Compounds for modulating cell proliferation |
ATE411300T1 (en) * | 2005-08-05 | 2008-10-15 | Hybrigenics Sa | NEW CYSTEINE PROTEASE HEMMERS AND THEIR THERAPEUTIC APPLICATIONS |
WO2007059613A1 (en) * | 2005-11-22 | 2007-05-31 | University Of Saskatchewan | Antineoplastic compounds |
US20120316203A1 (en) * | 2009-07-06 | 2012-12-13 | The Ohio State University Research Foundation | Compositions and Methods for Inhibition of Cancers |
PT2780326T (en) * | 2011-10-19 | 2019-03-04 | Vivolux Ab | Method for inhibition of deubiquitinating activity |
-
2012
- 2012-10-15 PT PT12841677T patent/PT2780326T/en unknown
- 2012-10-15 ES ES12841677T patent/ES2713484T3/en active Active
- 2012-10-15 JP JP2014537023A patent/JP6165748B2/en not_active Expired - Fee Related
- 2012-10-15 PL PL12841677T patent/PL2780326T3/en unknown
- 2012-10-15 CN CN201280062713.XA patent/CN104271557B/en not_active Expired - Fee Related
- 2012-10-15 BR BR112014009365-2A patent/BR112014009365B1/en not_active IP Right Cessation
- 2012-10-15 HU HUE12841677A patent/HUE041816T2/en unknown
- 2012-10-15 SG SG11201401608PA patent/SG11201401608PA/en unknown
- 2012-10-15 KR KR1020147012947A patent/KR102022575B1/en active IP Right Grant
- 2012-10-15 AU AU2012326682A patent/AU2012326682B2/en not_active Ceased
- 2012-10-15 WO PCT/SE2012/000158 patent/WO2013058691A1/en active Application Filing
- 2012-10-15 MX MX2014004646A patent/MX345467B/en active IP Right Grant
- 2012-10-15 EP EP12841677.3A patent/EP2780326B1/en active Active
- 2012-10-15 EA EA201490800A patent/EA026409B1/en not_active IP Right Cessation
- 2012-10-15 DK DK12841677.3T patent/DK2780326T3/en active
- 2012-10-15 CA CA2852518A patent/CA2852518C/en active Active
- 2012-10-15 MY MYPI2014001125A patent/MY169330A/en unknown
-
2014
- 2014-04-13 IL IL232118A patent/IL232118A/en active IP Right Grant
- 2014-04-17 CL CL2014000998A patent/CL2014000998A1/en unknown
- 2014-04-18 US US14/256,280 patent/US9221761B2/en not_active Expired - Fee Related
- 2014-05-08 ZA ZA2014/03302A patent/ZA201403302B/en unknown
-
2015
- 2015-04-16 HK HK15103712.4A patent/HK1203194A1/en not_active IP Right Cessation
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