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SG10201914069SA - Compositions and methods for tcr reprogramming using fusion proteins - Google Patents

Compositions and methods for tcr reprogramming using fusion proteins

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Publication number
SG10201914069SA
SG10201914069SA SG10201914069SA SG10201914069SA SG10201914069SA SG 10201914069S A SG10201914069S A SG 10201914069SA SG 10201914069S A SG10201914069S A SG 10201914069SA SG 10201914069S A SG10201914069S A SG 10201914069SA SG 10201914069S A SG10201914069S A SG 10201914069SA
Authority
SG
Singapore
Prior art keywords
compositions
methods
fusion proteins
reprogramming
tcr
Prior art date
Application number
SG10201914069SA
Inventor
Patrick Baeuerle
Gregory Sieczkiewicz
Robert Hofmeister
Original Assignee
Tcr2 Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57320750&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201914069S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tcr2 Therapeutics Inc filed Critical Tcr2 Therapeutics Inc
Publication of SG10201914069SA publication Critical patent/SG10201914069SA/en

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2319/00—Fusion polypeptide
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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SG10201914069SA 2015-05-18 2016-05-18 Compositions and methods for tcr reprogramming using fusion proteins SG10201914069SA (en)

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US201562163342P 2015-05-18 2015-05-18

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US (7) US10442849B2 (en)
EP (3) EP3298033B2 (en)
JP (4) JP2018515123A (en)
KR (1) KR20180029201A (en)
CN (2) CN107995913B (en)
AU (2) AU2016264323B2 (en)
BR (1) BR112017024757A2 (en)
CA (1) CA2986254A1 (en)
DK (1) DK3298033T4 (en)
EA (2) EA202090931A3 (en)
ES (1) ES2819976T5 (en)
FI (1) FI3298033T4 (en)
HK (1) HK1252643A1 (en)
HU (1) HUE051661T2 (en)
IL (2) IL303905A (en)
MX (1) MX2017014822A (en)
PL (1) PL3298033T5 (en)
PT (1) PT3298033T (en)
SG (1) SG10201914069SA (en)
WO (1) WO2016187349A1 (en)

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