SG10201810404XA - Combination comprising a glucocorticoid and edo-s101 - Google Patents
Combination comprising a glucocorticoid and edo-s101Info
- Publication number
- SG10201810404XA SG10201810404XA SG10201810404XA SG10201810404XA SG10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA
- Authority
- SG
- Singapore
- Prior art keywords
- combination
- glucocorticoid
- edo
- kit
- composition
- Prior art date
Links
- 239000003862 glucocorticoid Substances 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- GISXTRIGVCKQBX-UHFFFAOYSA-N 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-n-hydroxyheptanamide Chemical compound ClCCN(CCCl)C1=CC=C2N(C)C(CCCCCCC(=O)NO)=NC2=C1 GISXTRIGVCKQBX-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
COMBINATION COMPRISING A GLUCOCORTICOID AND EDO-S101 The present invention is directed to a combination comprising a glucocorticoid and a compound of formula I or a pharmaceutically acceptable salt thereof: ( I ) to a pharmaceutical composition and to a kit both comprising said combination, to the combination, composition or kit for use in the treatment of cancer, and to a method of treatment of cancer in a patient in need thereof comprising administering to said patient an effective amount of said combination, composition or kit. Figure 2 N N N Cl Cl HN OH O
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1409485.8A GB201409485D0 (en) | 2014-05-28 | 2014-05-28 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201810404XA true SG10201810404XA (en) | 2018-12-28 |
Family
ID=51177587
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201810404XA SG10201810404XA (en) | 2014-05-28 | 2015-05-26 | Combination comprising a glucocorticoid and edo-s101 |
SG11201609362YA SG11201609362YA (en) | 2014-05-28 | 2015-05-26 | Combination comprising a glucocorticoid and edo-s101 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201609362YA SG11201609362YA (en) | 2014-05-28 | 2015-05-26 | Combination comprising a glucocorticoid and edo-s101 |
Country Status (19)
Country | Link |
---|---|
US (4) | US10744120B2 (en) |
EP (1) | EP3148584B1 (en) |
JP (2) | JP2017518292A (en) |
KR (1) | KR20170008846A (en) |
CN (1) | CN106488776B (en) |
AU (1) | AU2015266053B2 (en) |
BR (1) | BR112016027043B1 (en) |
CA (1) | CA2950340C (en) |
DK (1) | DK3148584T3 (en) |
EA (1) | EA038323B1 (en) |
ES (1) | ES2885429T3 (en) |
GB (1) | GB201409485D0 (en) |
IL (1) | IL249230A0 (en) |
MX (1) | MX383254B (en) |
PH (1) | PH12016502352A1 (en) |
SG (2) | SG10201810404XA (en) |
TW (1) | TWI731837B (en) |
UA (1) | UA121392C2 (en) |
WO (1) | WO2015181157A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR092790A1 (en) | 2012-02-01 | 2015-05-06 | Euro Celtique Sa | BENCIMIDAZOLIC DERIVATIVES OF HYDROXAMIC ACID |
GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
GB201409488D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
US11266631B2 (en) | 2016-10-11 | 2022-03-08 | Purdue Pharmaceutical Products L.P. | Hodgkin lymphoma therapy |
GB201709406D0 (en) * | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
GB201709402D0 (en) * | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
KR20210105380A (en) * | 2018-12-18 | 2021-08-26 | 먼디파머 인터내셔널 코포레이션 리미티드 | Compounds for treating multiple myeloma |
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GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
KR20210105380A (en) | 2018-12-18 | 2021-08-26 | 먼디파머 인터내셔널 코포레이션 리미티드 | Compounds for treating multiple myeloma |
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2014
- 2014-05-28 GB GBGB1409485.8A patent/GB201409485D0/en not_active Ceased
-
2015
- 2015-05-26 CN CN201580027933.2A patent/CN106488776B/en active Active
- 2015-05-26 WO PCT/EP2015/061572 patent/WO2015181157A1/en active Application Filing
- 2015-05-26 US US15/314,180 patent/US10744120B2/en active Active
- 2015-05-26 DK DK15724308.0T patent/DK3148584T3/en active
- 2015-05-26 JP JP2016569598A patent/JP2017518292A/en active Pending
- 2015-05-26 EP EP15724308.0A patent/EP3148584B1/en active Active
- 2015-05-26 MX MX2016015437A patent/MX383254B/en unknown
- 2015-05-26 EA EA201692481A patent/EA038323B1/en unknown
- 2015-05-26 CA CA2950340A patent/CA2950340C/en active Active
- 2015-05-26 TW TW104116781A patent/TWI731837B/en active
- 2015-05-26 ES ES15724308T patent/ES2885429T3/en active Active
- 2015-05-26 UA UAA201613346A patent/UA121392C2/en unknown
- 2015-05-26 SG SG10201810404XA patent/SG10201810404XA/en unknown
- 2015-05-26 AU AU2015266053A patent/AU2015266053B2/en active Active
- 2015-05-26 BR BR112016027043-6A patent/BR112016027043B1/en active IP Right Grant
- 2015-05-26 SG SG11201609362YA patent/SG11201609362YA/en unknown
- 2015-05-26 KR KR1020167035845A patent/KR20170008846A/en not_active Ceased
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2016
- 2016-11-25 PH PH12016502352A patent/PH12016502352A1/en unknown
- 2016-11-27 IL IL249230A patent/IL249230A0/en unknown
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2020
- 2020-08-14 US US16/994,154 patent/US11541038B2/en active Active
- 2020-12-24 JP JP2020215171A patent/JP2021046446A/en active Pending
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2022
- 2022-12-19 US US18/083,651 patent/US12064417B2/en active Active
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2024
- 2024-07-17 US US18/775,245 patent/US20250049762A1/en active Pending
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