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SG10201700889PA - P2x7 modulators - Google Patents

P2x7 modulators

Info

Publication number
SG10201700889PA
SG10201700889PA SG10201700889PA SG10201700889PA SG10201700889PA SG 10201700889P A SG10201700889P A SG 10201700889PA SG 10201700889P A SG10201700889P A SG 10201700889PA SG 10201700889P A SG10201700889P A SG 10201700889PA SG 10201700889P A SG10201700889P A SG 10201700889PA
Authority
SG
Singapore
Prior art keywords
modulators
Prior art date
Application number
SG10201700889PA
Inventor
Vaca Manuel Jesus Alcazar
Brett D Allison
Gil Jose Ignacio Andres
Christa C Chrovian
Heather R Coate
Angelis Meri De
Xiaohu Deng
Curt A Dvorak
Christine F Gelin
Michael A Letavic
Jimmy T Liang
Neelakandha S Mani
Jason C Rech
Brad M Savall
Akinola Soyode-Johnson
Brice M Stenne
Devin M Swanson
Jessica L Wall
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG10201700889PA publication Critical patent/SG10201700889PA/en

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    • C07ORGANIC CHEMISTRY
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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
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    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
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    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
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    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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SG10201700889PA 2013-03-14 2014-03-14 P2x7 modulators SG10201700889PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361786260P 2013-03-14 2013-03-14

Publications (1)

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SG10201700889PA true SG10201700889PA (en) 2017-03-30

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US (8) US10112937B2 (en)
EP (3) EP2970267B3 (en)
JP (1) JP6293861B2 (en)
KR (4) KR102500076B1 (en)
CN (2) CN105209464B (en)
AR (2) AR095530A1 (en)
AU (5) AU2014239291B2 (en)
BR (1) BR112015023142B1 (en)
CA (1) CA2906085C (en)
CL (3) CL2015002655A1 (en)
CY (1) CY1119110T1 (en)
DK (2) DK2970267T6 (en)
EA (1) EA028816B1 (en)
ES (2) ES2635318T7 (en)
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HR (1) HRP20171168T4 (en)
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PT (2) PT3239151T (en)
RS (1) RS56315B2 (en)
SG (2) SG11201507259UA (en)
SI (1) SI2970267T1 (en)
TW (2) TWI599567B (en)
UA (1) UA116467C2 (en)
UY (3) UY39888A (en)
WO (1) WO2014152604A1 (en)
ZA (1) ZA201507627B (en)

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TWI599567B (en) 2013-03-14 2017-09-21 健生藥品公司 P2x7 modulators
MX363936B (en) 2013-03-14 2019-04-09 Boehringer Ingelheim Int Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c.
US9096596B2 (en) 2013-03-14 2015-08-04 Janssen Pharmaceutica Nv P2X7 modulators
JP6467404B2 (en) 2013-03-14 2019-02-13 ヤンセン ファーマシューティカ エヌ.ベー. P2X7 modulator
JO3509B1 (en) 2013-03-14 2020-07-05 Janssen Pharmaceutica Nv P2x7 modulators
GB201321748D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
WO2015172196A1 (en) * 2014-05-13 2015-11-19 Monash University Heterocyclic compounds and use of same
US10150766B2 (en) 2014-09-12 2018-12-11 Janssen Pharmaceutica Nv P2X7 modulators
SI3191487T1 (en) 2014-09-12 2019-12-31 Boehringer Ingelheim International Gmbh Spirocyclic inhibitors of cathepsin c
EP3287443B1 (en) 2015-04-24 2021-10-27 Shionogi & Co., Ltd 6-membered heterocyclic derivative and pharmaceutical composition comprising same
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