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SE9804551D0 - Arrangements useful for measurement and a measuring method that may utilize the arrangements - Google Patents

Arrangements useful for measurement and a measuring method that may utilize the arrangements

Info

Publication number
SE9804551D0
SE9804551D0 SE9804551A SE9804551A SE9804551D0 SE 9804551 D0 SE9804551 D0 SE 9804551D0 SE 9804551 A SE9804551 A SE 9804551A SE 9804551 A SE9804551 A SE 9804551A SE 9804551 D0 SE9804551 D0 SE 9804551D0
Authority
SE
Sweden
Prior art keywords
aotf
arrangements
laser
beam path
sources
Prior art date
Application number
SE9804551A
Other languages
Swedish (sv)
Inventor
Stig Tormod
Original Assignee
Amersham Pharm Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Pharm Biotech Ab filed Critical Amersham Pharm Biotech Ab
Priority to SE9804551A priority Critical patent/SE9804551D0/en
Publication of SE9804551D0 publication Critical patent/SE9804551D0/en
Priority to PCT/EP1999/010311 priority patent/WO2000039545A1/en
Priority to EP99966998A priority patent/EP1192431A1/en
Priority to JP2000591396A priority patent/JP2003522323A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/1256—Generating the spectrum; Monochromators using acousto-optic tunable filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G02—OPTICS
    • G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/01—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour 
    • G02F1/11—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour  based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nonlinear Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

A fluorescence measuring unit comprising a monochromatic light source (13), a detector unit (23a, 23b), an excitation beam (13a) going from the light source (13) to the spot (18), an emission beam going from the spot (18) to the detector unit (23a, 23b) and an acousto optic tuneable filter (AOTF) (12), arranged in a non-collinear mode, and such that the excitation beam path and the emission beam path coincide but propagate in the AOTF in opposite directions. An arrangement comprising two laser sources (27) defining two beam paths leading to a common beam path (31) with the features that: a) said laser sources have polarisation planes perpendicular to each other and b) a non-collinear AOTF (29) is placed in the conjunction of said two beam paths and oriented such that, when tuned to the respective wavelength of the laser light from the respective laser source, the laser light from the two sources will pass and exit the second AOTF (29) in one and the same beam path (31).
SE9804551A 1998-12-28 1998-12-28 Arrangements useful for measurement and a measuring method that may utilize the arrangements SE9804551D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9804551A SE9804551D0 (en) 1998-12-28 1998-12-28 Arrangements useful for measurement and a measuring method that may utilize the arrangements
PCT/EP1999/010311 WO2000039545A1 (en) 1998-12-28 1999-12-22 Fluorescence measuring device
EP99966998A EP1192431A1 (en) 1998-12-28 1999-12-22 Fluorescence measuring device
JP2000591396A JP2003522323A (en) 1998-12-28 1999-12-22 Fluorescence emission measurement device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9804551A SE9804551D0 (en) 1998-12-28 1998-12-28 Arrangements useful for measurement and a measuring method that may utilize the arrangements

Publications (1)

Publication Number Publication Date
SE9804551D0 true SE9804551D0 (en) 1998-12-28

Family

ID=20413866

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9804551A SE9804551D0 (en) 1998-12-28 1998-12-28 Arrangements useful for measurement and a measuring method that may utilize the arrangements

Country Status (4)

Country Link
EP (1) EP1192431A1 (en)
JP (1) JP2003522323A (en)
SE (1) SE9804551D0 (en)
WO (1) WO2000039545A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10031636B4 (en) * 2000-06-29 2006-01-05 Siemens Ag spectrometer
AT410033B (en) * 2001-06-06 2003-01-27 Eurolab Instr Gmbh METHOD AND MEASURING DEVICE FOR DETERMINING AT LEAST ONE LUMINESCENCE, FLOURENCE OR ABSORPTION PARAMETER OF A SAMPLE
CN1308740C (en) * 2002-11-22 2007-04-04 天津市先石光学技术有限公司 Method and apparatus for improving signal-to-noise ratio of acousto-optic tunable filter light splitting system
JP2007183111A (en) * 2006-01-04 2007-07-19 Nikon Corp Light intensity detection device, optical device provided with same, and microscope
DE102007028337B4 (en) * 2007-06-15 2019-08-29 Leica Microsystems Cms Gmbh Beam combiner and a light source with such a beam combiner
CN102820611B (en) * 2012-09-05 2014-06-04 天津奇谱光电技术有限公司 Tunable laser for outputting non-polarized light
DE102013227104B4 (en) * 2013-09-03 2018-05-30 Leica Microsystems Cms Gmbh Scanning microscope and acousto-optic main beam splitter for a scanning microscope
DE102013227103B4 (en) * 2013-09-03 2018-05-30 Leica Microsystems Cms Gmbh Microscope with an acousto-optic device
DE102013227107A1 (en) * 2013-09-03 2015-03-05 Leica Microsystems Cms Gmbh Microscope with an element for changing the shape of the illumination light focus
DE102013227105A1 (en) * 2013-09-03 2015-03-05 Leica Microsystems Cms Gmbh Microscope and acousto-optical beam combiner for a microscope
DE102013227108A1 (en) * 2013-09-03 2015-03-05 Leica Microsystems Cms Gmbh Apparatus and method for assaying a sample

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0252231A (en) * 1988-08-17 1990-02-21 Asahi Glass Co Ltd Light pulse tester
US5216484A (en) * 1991-12-09 1993-06-01 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Real-time imaging spectrometer
US5599717A (en) * 1994-09-02 1997-02-04 Martin Marietta Energy Systems, Inc. Advanced synchronous luminescence system
US5796512A (en) * 1996-02-16 1998-08-18 Carnegie Mellon University Subicron imaging system having an acousto-optic tunable filter

Also Published As

Publication number Publication date
EP1192431A1 (en) 2002-04-03
WO2000039545A1 (en) 2000-07-06
JP2003522323A (en) 2003-07-22

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