SE8305917D0 - INTERMEDIATES FOR USE IN THE PREPARATION OF HEXAHYDRO-GAMMA CARBOL COMPOUNDS - Google Patents
INTERMEDIATES FOR USE IN THE PREPARATION OF HEXAHYDRO-GAMMA CARBOL COMPOUNDSInfo
- Publication number
- SE8305917D0 SE8305917D0 SE8305917A SE8305917A SE8305917D0 SE 8305917 D0 SE8305917 D0 SE 8305917D0 SE 8305917 A SE8305917 A SE 8305917A SE 8305917 A SE8305917 A SE 8305917A SE 8305917 D0 SE8305917 D0 SE 8305917D0
- Authority
- SE
- Sweden
- Prior art keywords
- compounds
- hexahydro
- carbol
- intermediates
- gamma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Phenyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, which are substituted in position 2, and their salts of formula I, the symbols of which are explained in Claim 1, are described. These compounds and their salts are therapeutically active and can be used as medicaments for controlling schizophrenic symptoms. The pharmaceutical compositions are also described. The new compounds and their salts can be obtained by processes which are especially distinguished from others by the formation of the substituent in position 2; the latter is obtained by processes which each contain a reduction stage, from compounds which already have the pyridoindole system. <IMAGE>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79939277A | 1977-05-23 | 1977-05-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8305917D0 true SE8305917D0 (en) | 1983-10-27 |
| SE8305917L SE8305917L (en) | 1983-10-27 |
| SE448459B SE448459B (en) | 1987-02-23 |
Family
ID=25175793
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7803625A SE441448B (en) | 1977-05-23 | 1978-03-30 | SET TO MAKE HEXAHYDRO-GAMMA CARBOL COMPOUNDS |
| SE8305917A SE448459B (en) | 1977-05-23 | 1983-10-27 | 4A, 9B-TRANS-HEXAHYDRO-GAMMA CARBOL COMPOUNDS AS INTERMEDIATES FOR THE PREPARATION OF HEXAHYDRO-GAMMA CARBOL COMPOUNDS |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7803625A SE441448B (en) | 1977-05-23 | 1978-03-30 | SET TO MAKE HEXAHYDRO-GAMMA CARBOL COMPOUNDS |
Country Status (31)
| Country | Link |
|---|---|
| JP (1) | JPS53144600A (en) |
| AR (2) | AR217688A1 (en) |
| AT (1) | AT368995B (en) |
| AU (1) | AU499618B1 (en) |
| BE (1) | BE867249A (en) |
| CA (1) | CA1094071A (en) |
| CH (1) | CH634321A5 (en) |
| CS (1) | CS207612B2 (en) |
| DD (4) | DD138321A5 (en) |
| DE (1) | DE2822465C2 (en) |
| DK (1) | DK226678A (en) |
| EG (1) | EG13590A (en) |
| FI (1) | FI63402C (en) |
| FR (1) | FR2392023A1 (en) |
| GB (1) | GB1586655A (en) |
| GR (1) | GR69985B (en) |
| HU (3) | HU188802B (en) |
| IE (1) | IE46975B1 (en) |
| IL (1) | IL54755A (en) |
| IT (1) | IT1096307B (en) |
| LU (1) | LU79684A1 (en) |
| NL (1) | NL7804210A (en) |
| NO (2) | NO150204C (en) |
| NZ (1) | NZ187333A (en) |
| PH (1) | PH13756A (en) |
| PL (5) | PL116944B1 (en) |
| PT (1) | PT68058B (en) |
| SE (2) | SE441448B (en) |
| SU (4) | SU873883A3 (en) |
| YU (4) | YU91478A (en) |
| ZA (1) | ZA782918B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224329A (en) * | 1979-01-23 | 1980-09-23 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| US4451655A (en) * | 1982-05-17 | 1984-05-29 | Pfizer Inc. | Process for preparing carboline derivatives and compounds used in their preparation |
| RU2106864C1 (en) * | 1995-10-23 | 1998-03-20 | Николай Серафимович Зефиров | New approach to treatment of alzheimer's disease |
| SE9604786D0 (en) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| US6974825B1 (en) | 1996-12-20 | 2005-12-13 | Astrazeneca Canada Inc. | Compounds with analgesic effect |
| SE9904675D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0101773D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101769D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101771D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101770D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| DE20204239U1 (en) | 2002-03-16 | 2002-05-29 | Funke Kunststoffe GmbH, 48324 Sendenhorst | Universal Pipe Gasket |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205452A1 (en) * | 1973-12-06 | 1976-05-07 | Endo Lab | METHOD TO PREPARE NEW TRANS-2, 3, 4, 4A, 5, 9B-HEXAHYDRO-5-PHENYL-1H-PYRID (4,3-B) INDOLES |
| JPS50126699A (en) * | 1974-03-20 | 1975-10-04 | ||
| US4001263A (en) * | 1974-04-01 | 1977-01-04 | Pfizer Inc. | 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines |
-
1978
- 1978-03-30 SE SE7803625A patent/SE441448B/en unknown
- 1978-04-17 PH PH21013A patent/PH13756A/en unknown
- 1978-04-18 YU YU00914/78A patent/YU91478A/en unknown
- 1978-04-20 NL NL7804210A patent/NL7804210A/en not_active Application Discontinuation
- 1978-04-24 AU AU35377/78A patent/AU499618B1/en not_active Expired
- 1978-04-25 EG EG276/78A patent/EG13590A/en active
- 1978-04-28 AR AR271956A patent/AR217688A1/en active
- 1978-05-18 PL PL1978215923A patent/PL116944B1/en unknown
- 1978-05-18 HU HU822638A patent/HU188802B/en unknown
- 1978-05-18 PL PL1978206903A patent/PL114547B1/en unknown
- 1978-05-18 GB GB20350/78A patent/GB1586655A/en not_active Expired
- 1978-05-18 HU HU78PI626A patent/HU185009B/en unknown
- 1978-05-18 PL PL1978215922A patent/PL114541B1/en unknown
- 1978-05-18 PL PL1978215921A patent/PL117107B1/en unknown
- 1978-05-18 CS CS783239A patent/CS207612B2/en unknown
- 1978-05-18 SU SU782615898A patent/SU873883A3/en active
- 1978-05-18 HU HU822639A patent/HU187782B/en unknown
- 1978-05-19 DD DD78205479A patent/DD138321A5/en unknown
- 1978-05-19 DD DD78215015A patent/DD145536A5/en unknown
- 1978-05-19 DD DD78215017A patent/DD145537A5/en unknown
- 1978-05-19 BE BE187842A patent/BE867249A/en not_active IP Right Cessation
- 1978-05-19 CA CA303,710A patent/CA1094071A/en not_active Expired
- 1978-05-19 PT PT68058A patent/PT68058B/en unknown
- 1978-05-19 DD DD215016A patent/DD146186A5/en unknown
- 1978-05-20 GR GR56281A patent/GR69985B/el unknown
- 1978-05-22 CH CH552678A patent/CH634321A5/en not_active IP Right Cessation
- 1978-05-22 JP JP6087278A patent/JPS53144600A/en active Granted
- 1978-05-22 IL IL54755A patent/IL54755A/en unknown
- 1978-05-22 NO NO781770A patent/NO150204C/en unknown
- 1978-05-22 DK DK226678A patent/DK226678A/en not_active Application Discontinuation
- 1978-05-22 AT AT0369678A patent/AT368995B/en not_active IP Right Cessation
- 1978-05-22 LU LU79684A patent/LU79684A1/en unknown
- 1978-05-22 IE IE1013/78A patent/IE46975B1/en unknown
- 1978-05-22 NZ NZ187333A patent/NZ187333A/en unknown
- 1978-05-22 IT IT23673/78A patent/IT1096307B/en active
- 1978-05-22 ZA ZA00782918A patent/ZA782918B/en unknown
- 1978-05-22 FR FR7815029A patent/FR2392023A1/en active Granted
- 1978-05-22 FI FI781612A patent/FI63402C/en not_active IP Right Cessation
- 1978-05-23 DE DE2822465A patent/DE2822465C2/en not_active Expired
-
1979
- 1979-04-16 AR AR276191A patent/AR221721A1/en active
- 1979-04-24 SU SU792753359A patent/SU843749A3/en active
- 1979-04-26 SU SU792759902A patent/SU818484A3/en active
- 1979-05-18 PL PL20690379A patent/PL206903A1/en unknown
- 1979-05-18 SU SU792763595A patent/SU841589A3/en active
-
1982
- 1982-10-01 YU YU2217/82A patent/YU40796B/en unknown
- 1982-10-01 YU YU02218/82A patent/YU221882A/en unknown
- 1982-10-01 YU YU02216/82A patent/YU221682A/en unknown
-
1983
- 1983-05-20 NO NO831790A patent/NO151862C/en unknown
- 1983-10-27 SE SE8305917A patent/SE448459B/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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