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SE7803411L - 2,6-dialkoxibensamider - Google Patents

2,6-dialkoxibensamider

Info

Publication number
SE7803411L
SE7803411L SE7803411A SE7803411A SE7803411L SE 7803411 L SE7803411 L SE 7803411L SE 7803411 A SE7803411 A SE 7803411A SE 7803411 A SE7803411 A SE 7803411A SE 7803411 L SE7803411 L SE 7803411L
Authority
SE
Sweden
Prior art keywords
dialcoxibenzamides
Prior art date
Application number
SE7803411A
Other languages
English (en)
Other versions
SE411118B (sv
Inventor
G L Florvall
S-O Ogren
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Priority to SE7803411A priority Critical patent/SE411118B/sv
Priority to ZA79964A priority patent/ZA79964B/xx
Priority to CA322,555A priority patent/CA1101873A/en
Priority to EP79850013A priority patent/EP0004831B1/en
Priority to DE7979850013T priority patent/DE2964774D1/de
Priority to US06/018,784 priority patent/US4232037A/en
Priority to FI790922A priority patent/FI73979C/sv
Priority to NZ189935A priority patent/NZ189935A/en
Priority to AU45219/79A priority patent/AU525475B2/en
Priority to NO790934A priority patent/NO152414C/no
Priority to SU792739699A priority patent/SU818481A3/ru
Priority to DK117779A priority patent/DK157844C/da
Priority to ES478871A priority patent/ES478871A1/es
Priority to HU79AA924A priority patent/HU177793B/hu
Priority to DD79211750A priority patent/DD143605A5/de
Priority to CS791902A priority patent/CS226183B2/cs
Priority to JP54033429A priority patent/JPS585910B2/ja
Priority to AT0217779A priority patent/AT374173B/de
Priority to IE630/79A priority patent/IE48491B1/en
Publication of SE7803411L publication Critical patent/SE7803411L/sv
Publication of SE411118B publication Critical patent/SE411118B/sv
Priority to CA359,745A priority patent/CA1109484A/en
Priority to AT0253483A priority patent/AT389994B/de
Priority to SG518/85A priority patent/SG51885G/en
Priority to HK770/85A priority patent/HK77085A/xx
Priority to MY407/85A priority patent/MY8500407A/xx
Priority to AT0104286A priority patent/AT395147B/de
Priority to AT141289A priority patent/AT392274B/de
Priority to MX9203148A priority patent/MX9203148A/es
Priority to NL930052C priority patent/NL930052I2/nl
Priority to LU88308C priority patent/LU88308I2/fr
Priority to LV930821A priority patent/LV5469A3/xx
Priority to LTRP936A priority patent/LT2246B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7803411A 1978-03-23 1978-03-23 Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper SE411118B (sv)

Priority Applications (31)

Application Number Priority Date Filing Date Title
SE7803411A SE411118B (sv) 1978-03-23 1978-03-23 Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper
ZA79964A ZA79964B (en) 1978-03-23 1979-02-28 2,6-dialkoxybenzamides,intermediates,pharmaceutical compositions and methods for treatment of psychotic disorders
CA322,555A CA1101873A (en) 1978-03-23 1979-03-01 2,6-dialkoxybenzamides, intermediates, pharmaceutical compositions and methods for treatment of psychotic disorders
EP79850013A EP0004831B1 (en) 1978-03-23 1979-03-05 2,6-dialkoxybenzamides, process for their preparation, compositions and these compounds for use in the treatment of psychotic disordes
DE7979850013T DE2964774D1 (en) 1978-03-23 1979-03-05 2,6-dialkoxybenzamides, process for their preparation, compositions and these compounds for use in the treatment of psychotic disordes
US06/018,784 US4232037A (en) 1978-03-23 1979-03-08 2,6-Dialkoxybenzamides, intermediates, pharamaceutical compositions and methods for treatment of psychotic disorders
FI790922A FI73979C (sv) 1978-03-23 1979-03-19 Framställning av och mellanprodukter till 2,6-dialkoxibensamider
NZ189935A NZ189935A (en) 1978-03-23 1979-03-19 2,6-dialkoxybenzamide derivatives and pharmaceutical compositions
AU45219/79A AU525475B2 (en) 1978-03-23 1979-03-19 2,6-dialkoxybenzamidomethyl pyrrolidines
NO790934A NO152414C (no) 1978-03-23 1979-03-20 Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2,6-dialkoksybenzamider
DD79211750A DD143605A5 (de) 1978-03-23 1979-03-22 Verfahren zur herstellung von 2,6-dialkoxybenzamiden
CS791902A CS226183B2 (en) 1978-03-23 1979-03-22 Method of preparing n-ethyl-2-(2,6-dialkoxybenzamidomethyl)-pyrrolidine derivatives
DK117779A DK157844C (da) 1978-03-23 1979-03-22 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive n-alkyl-(2,6-dialkoxybenzamidometyl)-pyrrolidiner eller farmaceutisk acceptable salte deraf med syrer samt mellemprodukt til brug i fremgangsmaaden
ES478871A ES478871A1 (es) 1978-03-23 1979-03-22 Un procedimiento de preparacion de 2,6-dialcoxibenzamidas.
HU79AA924A HU177793B (en) 1978-03-23 1979-03-22 Process for producing 2,6-dialkoxy-benzamides
SU792739699A SU818481A3 (ru) 1978-03-23 1979-03-22 Способ получени производных бен-зАМидА или иХ СОлЕй или РАцЕМичЕСКиХСМЕСЕй, или СТЕРЕОизОМЕРОВ
JP54033429A JPS585910B2 (ja) 1978-03-23 1979-03-23 新規なジアルコキシベンズアミド類およびその製法
AT0217779A AT374173B (de) 1978-03-23 1979-03-23 Verfahren zur herstellung neuer 2,6 -dialkoxybenzamide, ihrer salze und stereoisomeren
IE630/79A IE48491B1 (en) 1978-03-23 1979-08-08 2,6-dialkoxybenzamides,process for their preparation,compositions and these compounds for use in the treatment of psychotic disorders
CA359,745A CA1109484A (en) 1978-03-23 1980-09-04 2,6-dialkoxybenzamides, intermediates, pharmaceutical compositions and methods for treatment of psychotic disorders
AT0253483A AT389994B (de) 1978-03-23 1983-07-11 Verwendung von neuen 2,6-dialkoxybenzamiden zur herstellung antipsychotischer heilmittel
SG518/85A SG51885G (en) 1978-03-23 1985-07-01 2,6-dialkoxybenzamides,process for their preparation,compositions and these compounds for use in the treatment of psychotic disorders
HK770/85A HK77085A (en) 1978-03-23 1985-10-10 2,6-dialkoxybenzamides,process for their preparation,compositions and these compounds for use in the treatment of psychotic disorders
MY407/85A MY8500407A (en) 1978-03-23 1985-12-30 2,6-dial koxybenzamides, process for their preparation compositions and these compounds for use in the treatment of psychotic discorders
AT0104286A AT395147B (de) 1978-03-23 1986-04-21 Verfahren zur herstellung und zur verwendung von neuen 3-brom-5-chlor-2,6-dialkoxybenzoesaeuren
AT141289A AT392274B (de) 1978-03-23 1989-06-08 2,6-dialkoxybenzamide
MX9203148A MX9203148A (es) 1978-03-23 1992-06-23 2,6-dialcoxipenzamidas y composiciones farmaceuticas que las contienen.
NL930052C NL930052I2 (nl) 1978-03-23 1993-06-10 2,6-Dialkoxybenzamiden, werkwijze ter bereiding ervan, samenstellingen en deze verbindingen voor toepassing bij de behandeling van psychotische afwijkingen.
LU88308C LU88308I2 (fr) 1978-03-23 1993-06-16 Remoxipride (Roxiam)
LV930821A LV5469A3 (lv) 1978-03-23 1993-06-30 Panemiens benzamida atvasinajumu vai to salu vai racemisko maisijumu vai stereoizomeru iegusanai
LTRP936A LT2246B (lt) 1978-03-23 1993-09-06 Benzamido dariniu ar ju drusku ar raceminiu misinuarba stereoizomeru gavimo budas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7803411A SE411118B (sv) 1978-03-23 1978-03-23 Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper

Publications (2)

Publication Number Publication Date
SE7803411L true SE7803411L (sv) 1979-09-24
SE411118B SE411118B (sv) 1979-12-03

Family

ID=20334412

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7803411A SE411118B (sv) 1978-03-23 1978-03-23 Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper

Country Status (26)

Country Link
US (1) US4232037A (sv)
EP (1) EP0004831B1 (sv)
JP (1) JPS585910B2 (sv)
AT (1) AT374173B (sv)
AU (1) AU525475B2 (sv)
CA (1) CA1101873A (sv)
CS (1) CS226183B2 (sv)
DD (1) DD143605A5 (sv)
DE (1) DE2964774D1 (sv)
DK (1) DK157844C (sv)
ES (1) ES478871A1 (sv)
FI (1) FI73979C (sv)
HK (1) HK77085A (sv)
HU (1) HU177793B (sv)
IE (1) IE48491B1 (sv)
LT (1) LT2246B (sv)
LU (1) LU88308I2 (sv)
MX (1) MX9203148A (sv)
MY (1) MY8500407A (sv)
NL (1) NL930052I2 (sv)
NO (1) NO152414C (sv)
NZ (1) NZ189935A (sv)
SE (1) SE411118B (sv)
SG (1) SG51885G (sv)
SU (1) SU818481A3 (sv)
ZA (1) ZA79964B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8101536L (sv) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Bensamid-derivat
US4470977A (en) * 1981-06-04 1984-09-11 Adria Laboratories, Inc. Antiemetic and antipsychotic agents
SE8205135D0 (sv) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-derivatives
US5240957A (en) * 1984-01-31 1993-08-31 Astra Lakemedel Akteibolag Oxysalicylamido derivatives
SE8400478D0 (sv) * 1984-01-31 1984-01-31 Astra Laekemedel Ab Oxysalicylamido derivatives
SE8503054D0 (sv) * 1985-06-19 1985-06-19 Astra Laekemedel Ab Catecholcarboxamides
DE3629598A1 (de) * 1986-08-30 1988-03-03 Boehringer Ingelheim Kg 3-brom-2,6-dimethoxibenzamide, ihre herstellung und verwendung
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
US4751236A (en) * 1987-05-20 1988-06-14 Avihou Mishniot Method for treating genital herpes
US5154913A (en) * 1987-11-19 1992-10-13 Vanderbilt University Radioiodinated benzamines method of their use as radioimaging agents
US5231099A (en) * 1991-04-15 1993-07-27 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists to enhance the effects of antipsychotic drugs
CA2112127A1 (en) * 1991-07-15 1993-02-04 Joseph Auerbach Novel process for aromatic bromination
US5248817A (en) * 1991-07-15 1993-09-28 Merck & Co., Inc. Process for aromatic bromination
CN104058956A (zh) * 2014-06-04 2014-09-24 蚌埠团结日用化学有限公司 3-溴-2，6二甲氧基苯甲酸合成的生产工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD67123A (sv) *
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (sv) * 1966-01-21 1968-05-06
BE695272A (sv) * 1967-03-09 1967-09-11
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
IT1070992B (it) * 1973-12-21 1985-04-02 Italfarmaco Spa Processo per la preparazione della i etil 2 2 metossi 5 sulfamoil benzamidometil pirrolidina
CH605793A5 (sv) * 1974-03-05 1978-10-13 Ile De France
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
IE42210B1 (en) * 1974-12-18 1980-06-18 Synthelabo 2-methoxy-benzamide derivatives

Also Published As

Publication number Publication date
DK117779A (da) 1979-09-24
FI73979B (fi) 1987-08-31
HU177793B (en) 1981-12-28
FI790922A (fi) 1979-09-24
JPS585910B2 (ja) 1983-02-02
NO790934L (no) 1979-09-25
ZA79964B (en) 1980-06-25
NL930052I1 (nl) 1993-09-01
ES478871A1 (es) 1979-07-01
CA1101873A (en) 1981-05-26
CS226183B2 (en) 1984-03-19
AU525475B2 (en) 1982-11-11
LU88308I2 (fr) 1994-05-04
DD143605A5 (de) 1980-09-03
AT374173B (de) 1984-03-26
SU818481A3 (ru) 1981-03-30
ATA217779A (de) 1983-08-15
MX9203148A (es) 1992-07-01
NZ189935A (en) 1984-07-06
DK157844B (da) 1990-02-26
DE2964774D1 (en) 1983-03-24
DK157844C (da) 1990-07-30
NO152414C (no) 1985-09-25
IE790630L (en) 1979-09-23
FI73979C (sv) 1987-12-10
SG51885G (en) 1986-01-24
MY8500407A (en) 1985-12-31
EP0004831A3 (en) 1979-10-31
LT2246B (lt) 1993-11-15
NO152414B (no) 1985-06-17
JPS54154730A (en) 1979-12-06
AU4521979A (en) 1979-09-27
IE48491B1 (en) 1985-02-06
NL930052I2 (nl) 1994-01-03
EP0004831B1 (en) 1983-02-16
EP0004831A2 (en) 1979-10-17
SE411118B (sv) 1979-12-03
HK77085A (en) 1985-10-18
US4232037A (en) 1980-11-04

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