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SE399423B - Forfarande for framstellning av prostaglandinanaloger - Google Patents

Forfarande for framstellning av prostaglandinanaloger

Info

Publication number
SE399423B
SE399423B SE7317599A SE7317599A SE399423B SE 399423 B SE399423 B SE 399423B SE 7317599 A SE7317599 A SE 7317599A SE 7317599 A SE7317599 A SE 7317599A SE 399423 B SE399423 B SE 399423B
Authority
SE
Sweden
Prior art keywords
innaloges
prostagland
procedure
production
prostagland innaloges
Prior art date
Application number
SE7317599A
Other languages
English (en)
Inventor
M Hayashi
H Wakatsuka
S Kori
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP242773A external-priority patent/JPS5336458B2/ja
Priority claimed from JP12279673A external-priority patent/JPS5653545B2/ja
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of SE399423B publication Critical patent/SE399423B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7317599A 1972-12-29 1973-12-28 Forfarande for framstellning av prostaglandinanaloger SE399423B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP242773A JPS5336458B2 (sv) 1972-12-29 1972-12-29
JP12279673A JPS5653545B2 (sv) 1973-11-02 1973-11-02

Publications (1)

Publication Number Publication Date
SE399423B true SE399423B (sv) 1978-02-13

Family

ID=26335786

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7317599A SE399423B (sv) 1972-12-29 1973-12-28 Forfarande for framstellning av prostaglandinanaloger

Country Status (11)

Country Link
US (1) US3931296A (sv)
AU (1) AU476655B2 (sv)
BE (1) BE809169A (sv)
CA (1) CA1026329A (sv)
CH (1) CH605727A5 (sv)
DE (1) DE2365035C2 (sv)
FR (1) FR2212146B1 (sv)
GB (1) GB1416410A (sv)
HK (1) HK14279A (sv)
NL (1) NL7317804A (sv)
SE (1) SE399423B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4052512A (en) * 1976-01-05 1977-10-04 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues
DE2700021A1 (de) * 1972-12-29 1977-07-14 Ono Pharmaceutical Co Prostaglandin-analoge
GB1482010A (en) * 1974-10-28 1977-08-03 Ono Pharmaceutical Co Prostaglandin analogues
GB1520942A (en) * 1976-02-10 1978-08-09 Ono Pharmaceutical Co Postaglandin analogues
US4165437A (en) * 1976-03-12 1979-08-21 Ono Pharmaceutical Company, Ltd. Δ3 -Prostaglandin analogs
GB1588196A (en) * 1977-06-14 1981-04-15 Ono Pharmaceutical Co Prostaglandin analogues
US4176282A (en) * 1978-03-21 1979-11-27 The Upjohn Company 2-Decarboxy-2-alkylcarbonyl-3,7-inter-m-phenylene-3-oxa-4,5,6-trinor-PGF1 compounds
US4123463A (en) * 1978-03-21 1978-10-31 The Upjohn Company 2-Decarboxy-2-alkylketone prostaglandins
DE2834249A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-11-desoxy-pgf tief 2 bzw. pge tief 2 -reihe
DK165111C (da) * 1979-01-25 1993-03-01 Ono Pharmaceutical Co Cyclopentanderivater samt fremgangsmaade til fremstilling deraf
JPS6036422B2 (ja) * 1979-01-29 1985-08-20 小野薬品工業株式会社 プロスタグランジン類似化合物及びその製造方法
JPS6033429B2 (ja) * 1980-04-28 1985-08-02 小野薬品工業株式会社 プロスタグランジン類似化合物
US4360688A (en) * 1981-05-21 1982-11-23 American Cyanamid Company Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
US5166369A (en) * 1981-05-21 1992-11-24 American Cyanamid Company Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
DE3315356A1 (de) * 1982-04-30 1983-11-17 Ono Pharmaceutical Co. Ltd., Osaka Verwendung von prostaglandinanalogen
JPS595154A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンd類似化合物
CN105985370B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用
CN105985371B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用
AU2017264102B2 (en) 2016-05-09 2020-09-24 AGC Inc. Novel prostaglandin derivative
WO2019087948A1 (ja) 2017-10-31 2019-05-09 Agc株式会社 プロスタグランジン誘導体の製造方法

Also Published As

Publication number Publication date
HK14279A (en) 1979-03-30
US3931296A (en) 1976-01-06
AU476655B2 (en) 1976-09-30
AU6407173A (en) 1975-07-03
DE2365035A1 (de) 1974-07-04
CA1026329A (en) 1978-02-14
GB1416410A (en) 1975-12-03
FR2212146B1 (sv) 1978-07-28
FR2212146A1 (sv) 1974-07-26
BE809169A (fr) 1974-06-27
NL7317804A (sv) 1974-07-02
CH605727A5 (sv) 1978-10-13
DE2365035C2 (de) 1986-04-24

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