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SE0101770D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101770D0
SE0101770D0 SE0101770A SE0101770A SE0101770D0 SE 0101770 D0 SE0101770 D0 SE 0101770D0 SE 0101770 A SE0101770 A SE 0101770A SE 0101770 A SE0101770 A SE 0101770A SE 0101770 D0 SE0101770 D0 SE 0101770D0
Authority
SE
Sweden
Prior art keywords
sub
sup
ring
phenyl
novel compounds
Prior art date
Application number
SE0101770A
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101770A priority Critical patent/SE0101770D0/sv
Publication of SE0101770D0 publication Critical patent/SE0101770D0/sv
Priority to ARP020101815A priority patent/AR033759A1/es
Priority to IL15862902A priority patent/IL158629A0/xx
Priority to BR0209669-2A priority patent/BR0209669A/pt
Priority to KR10-2003-7014948A priority patent/KR20040000469A/ko
Priority to US10/477,853 priority patent/US7064137B2/en
Priority to EEP200300534A priority patent/EE200300534A/xx
Priority to AT02736338T priority patent/ATE313529T1/de
Priority to HU0401608A priority patent/HUP0401608A2/hu
Priority to JP2002591456A priority patent/JP2005510456A/ja
Priority to MXPA03010441A priority patent/MXPA03010441A/es
Priority to PL02366390A priority patent/PL366390A1/xx
Priority to DE60208193T priority patent/DE60208193T2/de
Priority to EP02736338A priority patent/EP1395558B1/en
Priority to PCT/SE2002/000945 priority patent/WO2002094783A1/en
Priority to CNA028141709A priority patent/CN1620435A/zh
Priority to CA002446313A priority patent/CA2446313A1/en
Priority to CZ20033090A priority patent/CZ20033090A3/cs
Priority to SK1392-2003A priority patent/SK13922003A3/sk
Priority to RU2003131967/04A priority patent/RU2003131967A/ru
Priority to ZA200308637A priority patent/ZA200308637B/en
Priority to BG108331A priority patent/BG108331A/bg
Priority to CO03100167A priority patent/CO5540319A2/es
Priority to IS7031A priority patent/IS7031A/is
Priority to NO20035112A priority patent/NO20035112D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE0101770A 2001-05-18 2001-05-18 Novel compounds SE0101770D0 (sv)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds
RU2003131967/04A RU2003131967A (ru) 2001-05-18 2002-05-16 Производные 4-(фенил-(пиперидин-4-ил)-бензамида и их применение для лечения боли, тревоги или желудочно-кишечных расстройств
MXPA03010441A MXPA03010441A (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento del dolor, ansiedad o desordenes gastrointestinales.
DE60208193T DE60208193T2 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
BR0209669-2A BR0209669A (pt) 2001-05-18 2002-05-16 Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais e de lesões espinhais
KR10-2003-7014948A KR20040000469A (ko) 2001-05-18 2002-05-16 4-(페닐-(피페리딘-4-일)-아미노)-벤즈아미드 유도체 및통증, 불안증 또는 위장관 장애의 치료를 위한 그의 용도
US10/477,853 US7064137B2 (en) 2001-05-18 2002-05-16 4-(Phenyl-(piperidin-4-yl)-amino)-benzamide derivaties and their use for the treatment of pain, anxiety or gastrointestinal disorders
EEP200300534A EE200300534A (et) 2001-05-18 2002-05-16 4-(fenüül(piperidiin-4-üül)amino)bensamiidi derivaadid ja nende kasutamine valu, ärevuse või seedetrakti häirete raviks
AT02736338T ATE313529T1 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
HU0401608A HUP0401608A2 (hu) 2001-05-18 2002-05-16 4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
JP2002591456A JP2005510456A (ja) 2001-05-18 2002-05-16 ４−（フェニル−（ピペリジン−４−イル）−アミノ）−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
ARP020101815A AR033759A1 (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)amino)benzamida
PL02366390A PL366390A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
IL15862902A IL158629A0 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
EP02736338A EP1395558B1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
PCT/SE2002/000945 WO2002094783A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
CNA028141709A CN1620435A (zh) 2001-05-18 2002-05-16 4－(苯基－(哌啶－4－基)－氨基)－苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠病中的应用
CA002446313A CA2446313A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
CZ20033090A CZ20033090A3 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
SK1392-2003A SK13922003A3 (sk) 2001-05-18 2002-05-16 4-(Fenyl-(piperidín-4-yl)-amino)benzamidové deriváty a ich požitie na liečbu bolesti, anxiety alebo gastrointestinálnych porúch
ZA200308637A ZA200308637B (en) 2001-05-18 2003-11-05 4-[Phenyl-(piperidin-4-yl)-amino]-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders.
BG108331A BG108331A (bg) 2001-05-18 2003-11-07 4-(фенил-(пиперидин-4-ил)-амино)-бензамидни производни и тяхното използване за лечението на болка, потиснатост или стомашно-чревни разстройства
CO03100167A CO5540319A2 (es) 2001-05-18 2003-11-12 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales
IS7031A IS7031A (is) 2001-05-18 2003-11-13 4-(fenýl-(píperidín-4-ýl)-amínó)-bensamíðafleiðurog notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum
NO20035112A NO20035112D0 (no) 2001-05-18 2003-11-17 4-(fenyl-(piperidin-4-yl)-amino)-benzamidderivater og deres anvendelse vedbehandling av smerte, angst eller gastrointestinale forstyrrelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101770D0 true SE0101770D0 (sv) 2001-05-18

Family

ID=20284173

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Country Status (25)

Country Link
US (1) US7064137B2 (sv)
EP (1) EP1395558B1 (sv)
JP (1) JP2005510456A (sv)
KR (1) KR20040000469A (sv)
CN (1) CN1620435A (sv)
AR (1) AR033759A1 (sv)
AT (1) ATE313529T1 (sv)
BG (1) BG108331A (sv)
BR (1) BR0209669A (sv)
CA (1) CA2446313A1 (sv)
CO (1) CO5540319A2 (sv)
CZ (1) CZ20033090A3 (sv)
DE (1) DE60208193T2 (sv)
EE (1) EE200300534A (sv)
HU (1) HUP0401608A2 (sv)
IL (1) IL158629A0 (sv)
IS (1) IS7031A (sv)
MX (1) MXPA03010441A (sv)
NO (1) NO20035112D0 (sv)
PL (1) PL366390A1 (sv)
RU (1) RU2003131967A (sv)
SE (1) SE0101770D0 (sv)
SK (1) SK13922003A3 (sv)
WO (1) WO2002094783A1 (sv)
ZA (1) ZA200308637B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
CA2541014A1 (en) 2003-10-01 2005-04-14 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
WO2016099394A1 (en) * 2014-12-19 2016-06-23 Pharmnovo Ab Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091096A (en) 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
SE441448B (sv) 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
US4252812A (en) 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
DE3200304A1 (de) 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
YU150489A (sh) 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
KR940003491B1 (ko) 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
US5854245A (en) 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
DE69831876T2 (de) 1997-12-24 2006-07-27 Ortho-Mcneil Pharmaceutical, Inc. (4)-[aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden
CA2324418C (en) 1998-03-10 2010-02-02 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
CN1426411A (zh) * 2000-03-03 2003-06-25 奥索-麦克尼尔药品公司 3－(二芳基亚甲基)－8－氮杂双环[3.2.1]辛烷衍生物
US6556387B1 (en) * 2000-03-31 2003-04-29 Seagate Technology Llc Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
EP1395558A1 (en) 2004-03-10
CN1620435A (zh) 2005-05-25
DE60208193T2 (de) 2006-07-13
SK13922003A3 (sk) 2004-04-06
ZA200308637B (en) 2005-02-07
IS7031A (is) 2003-11-13
AR033759A1 (es) 2004-01-07
RU2003131967A (ru) 2005-05-10
EP1395558B1 (en) 2005-12-21
HUP0401608A2 (hu) 2004-12-28
US20040152731A1 (en) 2004-08-05
MXPA03010441A (es) 2004-03-09
CZ20033090A3 (en) 2004-06-16
NO20035112D0 (no) 2003-11-17
EE200300534A (et) 2004-02-16
KR20040000469A (ko) 2004-01-03
US7064137B2 (en) 2006-06-20
CO5540319A2 (es) 2005-07-29
JP2005510456A (ja) 2005-04-21
BR0209669A (pt) 2004-04-20
BG108331A (bg) 2004-10-29
IL158629A0 (en) 2004-05-12
PL366390A1 (en) 2005-01-24
CA2446313A1 (en) 2002-11-28
ATE313529T1 (de) 2006-01-15
DE60208193D1 (de) 2006-01-26
WO2002094783A1 (en) 2002-11-28

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