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RU98106859A - A NEW ANTIBODY, A RENIN ACTIVITY COMPOUND CONTAINING A NEW ANTIBODY, AND A REAGENT FOR DETERMINING PROENININE USING A NEW ANTIBODY - Google Patents

A NEW ANTIBODY, A RENIN ACTIVITY COMPOUND CONTAINING A NEW ANTIBODY, AND A REAGENT FOR DETERMINING PROENININE USING A NEW ANTIBODY

Info

Publication number
RU98106859A
RU98106859A RU98106859/13A RU98106859A RU98106859A RU 98106859 A RU98106859 A RU 98106859A RU 98106859/13 A RU98106859/13 A RU 98106859/13A RU 98106859 A RU98106859 A RU 98106859A RU 98106859 A RU98106859 A RU 98106859A
Authority
RU
Russia
Prior art keywords
new antibody
determining
human prorenin
renin activity
proeninine
Prior art date
Application number
RU98106859/13A
Other languages
Russian (ru)
Other versions
RU2198894C2 (en
Inventor
Мураками Казуо
Накамура Юкио
Сузуки Фумиаки
Исида Юити
Хатано Ясухико
Original Assignee
Токива Кемикал Индастриз Ко., Лтд.
Исида Юити
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP08853897A external-priority patent/JP3271157B2/en
Application filed by Токива Кемикал Индастриз Ко., Лтд., Исида Юити filed Critical Токива Кемикал Индастриз Ко., Лтд.
Publication of RU98106859A publication Critical patent/RU98106859A/en
Application granted granted Critical
Publication of RU2198894C2 publication Critical patent/RU2198894C2/en

Links

Claims (3)

1. Антитело против N-концевого пептида профрагмента проренина человека, способное специфически распознавать пептид, содержащий по меньшей мере 15 аминокислотных остатков с первого остатка лейцина до 15-го остатка аргинина в N-концевом пептиде профрагмента проренина человека.1. Antibody against the N-terminal peptide of human prorenin profragment, capable of specifically recognizing a peptide containing at least 15 amino acid residues from the first leucine residue to the 15th arginine residue in the N-terminal peptide of human prorenin profragment. 2. Соединение с активностью ренина, состоящее из комплекса антитела против N-концевого пептида профрагмента проренина человека по п.1, с проренином человека. 2. The compound with renin activity, consisting of a complex of antibodies against the N-terminal peptide of human prorenin profragment according to claim 1, with human prorenin. 3. Метод определения проренина человека в крови, предусматривающий (а) взаимодействие проренина человека в крови с антителом против N-концевого пептида профрагмента проренина человека по п.1 для формирования соединения с активностью проренина по п. 2; (b) добавление ангиотензиногена в качестве субстрата ренина к соединению с активностью ренина для образования ангиотензина I; и (c) определение ангиотензина I. 3. A method for determining human prorenin in the blood, comprising (a) the interaction of human prorenin in the blood with an antibody against the N-terminal peptide of human prorenin profragment according to claim 1 for forming a compound with prorenin activity according to claim 2; (b) adding angiotensinogen as a renin substrate to a compound with renin activity to form angiotensin I; and (c) determination of angiotensin I.
RU98106859/13A 1997-04-07 1998-04-06 Novel antibody, compound with renin activity comprising novel antibody and method of prorenin assay using novel antibody RU2198894C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP08853897A JP3271157B2 (en) 1997-04-07 1997-04-07 Novel antibody, renin active substance containing the same, and prorenin measuring reagent using the same
JP9-88538 1997-04-07

Publications (2)

Publication Number Publication Date
RU98106859A true RU98106859A (en) 2000-02-10
RU2198894C2 RU2198894C2 (en) 2003-02-20

Family

ID=13945630

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98106859/13A RU2198894C2 (en) 1997-04-07 1998-04-06 Novel antibody, compound with renin activity comprising novel antibody and method of prorenin assay using novel antibody

Country Status (18)

Country Link
US (1) US5945512A (en)
EP (1) EP0873999B1 (en)
JP (1) JP3271157B2 (en)
KR (1) KR100457445B1 (en)
CN (1) CN1194017C (en)
AR (1) AR011214A1 (en)
AT (1) ATE189897T1 (en)
AU (1) AU732018B2 (en)
BR (1) BR9801000A (en)
CA (1) CA2234204C (en)
CZ (1) CZ103698A3 (en)
DE (1) DE69800080T2 (en)
ES (1) ES2144328T3 (en)
HU (1) HUP9800782A3 (en)
ID (1) ID20535A (en)
PL (1) PL325735A1 (en)
RU (1) RU2198894C2 (en)
TW (1) TW381179B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2285700C (en) * 1998-10-13 2005-12-06 Tokiwa Chemical Industries Co., Ltd. Renin-active substance
WO2001056383A1 (en) * 2000-02-07 2001-08-09 Trustees Of Dartmouth College Compositions and methods for treatment of toxoplasma gondii and other apicomplexans
EP1273914A4 (en) * 2000-04-10 2004-08-25 Yuichi Ishida Hypotensors
EP2394159B1 (en) * 2009-02-04 2018-09-26 Molecular Innovations Assays for detecting prorenin, and antibodies used therein
JP6198047B2 (en) * 2013-08-02 2017-09-20 国立大学法人岐阜大学 Coronary artery disease test kit
JP6836748B2 (en) * 2016-10-21 2021-03-03 富士レビオ株式会社 Immunological measurement of renin concentration
CN116380882A (en) * 2023-03-21 2023-07-04 深圳泰乐德医疗有限公司 Renin magnetic particle chemiluminescence detection kit, preparation method and application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0387200A (en) * 1989-08-31 1991-04-11 Saitetsuku Res:Kk Monoclonal antibody
JPH08285852A (en) * 1995-04-14 1996-11-01 Tokiwa Kagaku Kogyo Kk Reagent for measuring human prorenin and measuring method using the same

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