RU93004764A - AMIDA SULFAMIDO-AND SULFAMIDOKARBONYLPYRIDIN-2-CARBIC ACIDS, THEIR Pyridine-N-OXIDES, METHOD OF THEIR RECEIVING AND THEIR APPLICATION AS MEDICINE PREPARATIONS - Google Patents
AMIDA SULFAMIDO-AND SULFAMIDOKARBONYLPYRIDIN-2-CARBIC ACIDS, THEIR Pyridine-N-OXIDES, METHOD OF THEIR RECEIVING AND THEIR APPLICATION AS MEDICINE PREPARATIONSInfo
- Publication number
- RU93004764A RU93004764A RU93004764/04A RU93004764A RU93004764A RU 93004764 A RU93004764 A RU 93004764A RU 93004764/04 A RU93004764/04 A RU 93004764/04A RU 93004764 A RU93004764 A RU 93004764A RU 93004764 A RU93004764 A RU 93004764A
- Authority
- RU
- Russia
- Prior art keywords
- sulfamidokarbonylpyridin
- amida
- carbic
- sulfamido
- pyridine
- Prior art date
Links
- 241000670727 Amida Species 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000001408 amides Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 230000003176 fibrotic Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 125000005420 sulfonamido group Chemical group S(=O)(=O)(N*)* 0.000 claims 1
- -1 sulfonamidocarbonylpyridine-2-carboxylic acid Chemical class 0.000 claims 1
Claims (1)
и их применение в качестве лекарственных препаратов, в частности для лечения фиброзных заболеваний.SUBSTANCE: invention relates to amides of sulfonamido and sulfonamidocarbonylpyridine-2-carboxylic acid of the general formula (I)
and their use as drugs, in particular for the treatment of fibrotic diseases.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4209424.0 | 1992-03-24 | ||
| DEP4209424,0 | 1992-03-24 | ||
| DE4209424 | 1992-03-24 | ||
| DE4238506 | 1992-11-14 | ||
| DEP4238506.7 | 1992-11-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93004764A true RU93004764A (en) | 1996-01-27 |
| RU2129545C1 RU2129545C1 (en) | 1999-04-27 |
Family
ID=25913130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93004764A RU2129545C1 (en) | 1992-03-24 | 1993-03-23 | Sulfamido- and sulfamido-carbonylpyridine-2-carboxylic acid amides, method of their synthesis and pharmaceutical composition |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5607954A (en) |
| EP (1) | EP0562512B1 (en) |
| JP (1) | JPH0649030A (en) |
| KR (1) | KR930019630A (en) |
| CN (1) | CN1076691A (en) |
| AT (1) | ATE199250T1 (en) |
| AU (1) | AU657608B2 (en) |
| CA (1) | CA2092276A1 (en) |
| CZ (1) | CZ46393A3 (en) |
| DE (1) | DE59310146D1 (en) |
| DK (1) | DK0562512T3 (en) |
| ES (1) | ES2154266T3 (en) |
| FI (1) | FI102895B1 (en) |
| GR (1) | GR3035479T3 (en) |
| HK (1) | HK1011987A1 (en) |
| HU (2) | HU219224B (en) |
| MY (1) | MY109143A (en) |
| NO (1) | NO179867C (en) |
| NZ (1) | NZ247201A (en) |
| PL (1) | PL173677B1 (en) |
| PT (1) | PT562512E (en) |
| RU (1) | RU2129545C1 (en) |
| SK (1) | SK280884B6 (en) |
| TW (1) | TW352384B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2101420T3 (en) * | 1993-11-02 | 1997-07-01 | Hoechst Ag | ESTERS-AMIDES OF SUBSTITUTED HETERO-CYCLIC CARBOXYL ACIDS, THEIR PREPARATION AND THEIR USE AS MEDICINES. |
| DK0650961T3 (en) * | 1993-11-02 | 1997-09-15 | Hoechst Ag | Substituted heterocyclic carboxylic acid amides, their preparation and their use as drugs. |
| CA2138929A1 (en) * | 1993-12-30 | 1995-07-01 | Klaus Weidmann | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals |
| DE4410423A1 (en) * | 1994-03-25 | 1995-09-28 | Hoechst Ag | Sulfonamidocarbonylpyridin-2-carboxamides and their pyridine N-oxides, processes for their preparation and their use as medicaments |
| DE4410453A1 (en) * | 1994-03-25 | 1995-09-28 | Hoechst Ag | Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments |
| DE4410480A1 (en) * | 1994-03-25 | 1995-09-28 | Hoechst Ag | Sulfonamidocarbonylpyridine-2-carboxylic acid ester amides and their pyridine N-oxides, processes for their preparation and their use as medicaments |
| DE4410454A1 (en) * | 1994-03-25 | 1995-09-28 | Hoechst Ag | Substituted heterocyclic carboxamides, their preparation and their use as medicines |
| IL135495A (en) * | 1995-09-28 | 2002-12-01 | Hoechst Ag | Intermediate compounds for the preparation of substituted quinoline-2-carboxylic acid amides |
| DE19742951A1 (en) * | 1997-09-29 | 1999-04-15 | Hoechst Schering Agrevo Gmbh | Acylsulfamoylbenzoic acid amides, crop protection agents containing them and process for their preparation |
| DE19746287A1 (en) * | 1997-10-20 | 1999-04-22 | Hoechst Marion Roussel De Gmbh | Substituted isoquinoline-2-carboxylic acid amides, their preparation and their use as medicaments |
| AR015733A1 (en) | 1998-03-25 | 2001-05-16 | Otsuka Pharma Co Ltd | PIRIDINE DERIVATIVE, THE PRODUCT AND THE PHARMACEUTICAL COMPOSITION CONTAINING SUCH DERIVATIVE. |
| US6583318B2 (en) | 2001-05-17 | 2003-06-24 | Advanced Syntech, Llc | Method for synthesis of α-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives |
| CA3094774A1 (en) * | 2001-12-06 | 2003-07-03 | Fibrogen, Inc. | Use of hif prolyl hydroxylase inhibitors for treating neurological disorders |
| EP2295060B1 (en) | 2001-12-06 | 2018-10-31 | Fibrogen, Inc. | Treatment or prevention of ischemic or hypoxic conditions |
| US8124582B2 (en) * | 2002-12-06 | 2012-02-28 | Fibrogen, Inc. | Treatment of diabetes |
| US7618940B2 (en) | 2002-12-06 | 2009-11-17 | Fibrogen, Inc. | Fat regulation |
| US8614204B2 (en) | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
| CN101242817B (en) | 2005-06-15 | 2016-08-31 | 菲布罗根公司 | HIF1 alpha modulators purposes in treatment cancer |
| US8565303B2 (en) * | 2006-03-30 | 2013-10-22 | Lg Electronics Inc. | Method and apparatus for decoding/encoding a video signal |
| HUE041300T2 (en) | 2006-06-26 | 2019-05-28 | Akebia Therapeutics Inc | Prolyl hydroxylase inhibitors and methods of use |
| US8193194B2 (en) * | 2007-05-25 | 2012-06-05 | Vertex Pharmaceuticals Incorporated | Ion channel modulators and methods of use |
| WO2009002533A1 (en) * | 2007-06-27 | 2008-12-31 | The Brigham And Women's Hospital, Inc. | Inflammatory bowel disease therapies |
| NO2686520T3 (en) | 2011-06-06 | 2018-03-17 | ||
| WO2013126608A1 (en) | 2012-02-22 | 2013-08-29 | Sanford-Burnham Medical Research Institute | Sulfonamide compounds and uses as tnap inhibitors |
| TW201512171A (en) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | Chemical compounds |
| HRP20240319T1 (en) | 2013-06-13 | 2024-05-24 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| KR102495018B1 (en) | 2013-11-15 | 2023-02-06 | 아케비아 테라퓨틱스 인코포레이티드 | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| CN107427503A (en) | 2015-01-23 | 2017-12-01 | 阿克比治疗有限公司 | The solid form, its composition and purposes of 2 (5 (3 fluorophenyl) 3 pyridone formamide) acetic acid |
| CN106146395B (en) * | 2015-03-27 | 2019-01-01 | 沈阳三生制药有限责任公司 | 3- hydroxypyridine compound, preparation method and its pharmaceutical applications |
| US11324734B2 (en) | 2015-04-01 | 2022-05-10 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| AU2019265629B2 (en) | 2018-05-09 | 2024-09-12 | Akebia Therapeutics, Inc. | Process for preparing 2-((5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)amino)acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| CN111972405A (en) * | 2020-07-27 | 2020-11-24 | 南京太化化工有限公司 | Auxiliary agent for suspending agent and isoxaflutole suspending agent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3432094A1 (en) * | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | ESTER OF PYRIDINE-2,4- AND -2,5-DICARBONIC ACID AS A MEDICINAL PRODUCT FOR INHIBITING PROLIN AND LYSINE HYDROXYLASE |
| US5153208A (en) * | 1987-02-10 | 1992-10-06 | Hoechst Aktiengesellschaft | Pyridine-2,4- and -2,5-dicarboxylic acid amides and their medicinal compositions and methods of use |
| DE3703962A1 (en) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | PYRIDINE-2,4- AND 2,5-DICARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE OF THE SAME AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS |
| DE3703959A1 (en) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | PYRIDINE-2,4- AND 2,5-DICARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, USE OF THE SAME AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS |
| DE3928144A1 (en) * | 1989-08-25 | 1991-02-28 | Hoechst Ag | CYCLIC PYRIDINE-2,4- AND -2,5-DICARBONIC ACIDEDIAMIDES, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DE4020570A1 (en) * | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- AND 2,5-SUBSTITUTED PYRIDINE-N-OXIDES, METHOD FOR THE PRODUCTION AND USE THEREOF |
-
1993
- 1993-03-09 TW TW082101698A patent/TW352384B/en active
- 1993-03-19 NZ NZ247201A patent/NZ247201A/en unknown
- 1993-03-22 DK DK93104658T patent/DK0562512T3/en active
- 1993-03-22 CZ CZ93463A patent/CZ46393A3/en unknown
- 1993-03-22 PT PT93104658T patent/PT562512E/en unknown
- 1993-03-22 FI FI931250A patent/FI102895B1/en active
- 1993-03-22 ES ES93104658T patent/ES2154266T3/en not_active Expired - Lifetime
- 1993-03-22 AT AT93104658T patent/ATE199250T1/en not_active IP Right Cessation
- 1993-03-22 DE DE59310146T patent/DE59310146D1/en not_active Expired - Fee Related
- 1993-03-22 SK SK223-93A patent/SK280884B6/en unknown
- 1993-03-22 MY MYPI93000506A patent/MY109143A/en unknown
- 1993-03-22 EP EP93104658A patent/EP0562512B1/en not_active Expired - Lifetime
- 1993-03-23 AU AU35369/93A patent/AU657608B2/en not_active Ceased
- 1993-03-23 PL PL93298195A patent/PL173677B1/en unknown
- 1993-03-23 CA CA002092276A patent/CA2092276A1/en not_active Abandoned
- 1993-03-23 NO NO931056A patent/NO179867C/en not_active IP Right Cessation
- 1993-03-23 JP JP5063723A patent/JPH0649030A/en active Pending
- 1993-03-23 CN CN93103349A patent/CN1076691A/en active Pending
- 1993-03-23 RU RU93004764A patent/RU2129545C1/en active
- 1993-03-24 HU HU9300850A patent/HU219224B/en not_active IP Right Cessation
- 1993-03-24 KR KR1019930004589A patent/KR930019630A/en not_active Application Discontinuation
-
1994
- 1994-12-13 US US08/355,419 patent/US5607954A/en not_active Expired - Fee Related
-
1995
- 1995-01-17 HU HU95P/P00068P patent/HU210714A9/en unknown
-
1998
- 1998-12-11 HK HK98113239A patent/HK1011987A1/en not_active IP Right Cessation
-
2001
- 2001-02-28 GR GR20010400321T patent/GR3035479T3/en not_active IP Right Cessation
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