RU2725197C1 - Visceral hypersensitivity assessment method - Google Patents
Visceral hypersensitivity assessment method Download PDFInfo
- Publication number
- RU2725197C1 RU2725197C1 RU2020106681A RU2020106681A RU2725197C1 RU 2725197 C1 RU2725197 C1 RU 2725197C1 RU 2020106681 A RU2020106681 A RU 2020106681A RU 2020106681 A RU2020106681 A RU 2020106681A RU 2725197 C1 RU2725197 C1 RU 2725197C1
- Authority
- RU
- Russia
- Prior art keywords
- temperature
- water
- day
- hypersensitivity
- visceral hypersensitivity
- Prior art date
Links
- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 10
- 208000026935 allergic disease Diseases 0.000 title claims abstract description 10
- 230000009610 hypersensitivity Effects 0.000 title claims abstract description 10
- 238000000034 method Methods 0.000 title claims abstract description 8
- 230000009278 visceral effect Effects 0.000 title claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims abstract description 6
- 239000003651 drinking water Substances 0.000 claims abstract description 5
- 235000020188 drinking water Nutrition 0.000 claims abstract description 5
- 201000006549 dyspepsia Diseases 0.000 claims abstract description 5
- 208000024891 symptom Diseases 0.000 claims abstract description 5
- 230000035622 drinking Effects 0.000 claims abstract description 4
- 239000012530 fluid Substances 0.000 abstract description 4
- 210000002784 stomach Anatomy 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract 2
- 206010000060 Abdominal distension Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 230000000291 postprandial effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Задачей заявленного изобретения является разработка метода оценки висцеральной гиперчувствительности более простым, неинвазивным и доступным способом. Решением вышеуказанной задачи оказалось проведение питьевого теста с использованием негазированной питьевой воды разной температуры до чувства полного насыщения. Уменьшение объема выпитой жидкости при увеличении температуры принимаемой воды на 50% и более свидетельствует о наличии температурной гиперчувствительности.The objective of the claimed invention is to develop a method for assessing visceral hypersensitivity in a simpler, non-invasive and affordable way. The solution to the above problem was to conduct a drinking test using non-carbonated drinking water of different temperatures to a feeling of full saturation. A decrease in the volume of fluid drunk with an increase in the temperature of the intake water by 50% or more indicates the presence of temperature hypersensitivity.
Предложенный нами метод осуществляется следующим образом. Утром, натощак, в течение 2-х дней исследуемый употребляет негазированную питьевую воду разной температуры (1-й день - 25°С, 2-й день 40°С) до чувства полного насыщения с последующей фиксацией объема выпитой жидкости. Уменьшение объема выпитой жидкости при увеличении температуры принимаемой воды на 50 и более процентов свидетельствует о наличии температурной гиперчувствительности.Our proposed method is as follows. In the morning, on an empty stomach, for 2 days, the researched consumes non-carbonated drinking water of different temperatures (1st day - 25 ° C, 2nd day 40 ° C) until a feeling of full saturation with subsequent fixation of the volume of liquid drunk. A decrease in the volume of fluid drunk with an increase in the temperature of the water taken by 50 percent or more indicates the presence of temperature hypersensitivity.
Преимуществами предложенного нами способа является одновременная оценка как механической (растяжение желудка водой), так и температурной (вода разной температуры) висцеральной гиперчувствительности. Поскольку исследование проводится с использованием обычной негазированной воды, то для его проведения не требуется дополнительного оборудования и специально обученного персонала. Также данный метод может использоваться как в стационарных, так и в амбулаторных условиях.The advantages of our proposed method is the simultaneous assessment of both mechanical (stretching of the stomach with water) and temperature (water of different temperatures) visceral hypersensitivity. Since the study is carried out using ordinary still water, it does not require additional equipment and specially trained personnel. Also, this method can be used both in inpatient and outpatient settings.
Пример 1. Нами было проведено исследование с использованием предложенного метода. Все обследуемые в течение двух дней употребляли негазированную питьевую воду (1-й день - 25°С, 2-й день – 40°С) до чувства полного насыщения с фиксированием выпитых объемов жидкости. Для проведения сравнительного анализа были сформированы 2 группы: 1-я группа пациенты с симптомами функциональной диспепсии, включающей синдром эпигастральной боли и постпрандиальный дистресс-синдром; 2-я группа – исследуемые, не имеющие симптомов функциональной диспепсии.Example 1. We conducted a study using the proposed method. All the subjects consumed non-carbonated drinking water (day 1 - 25 ° C, day 2 - 40 ° C) for two days until they felt completely saturated with a fixation of the amount of liquid drunk. To conduct a comparative analysis, 2 groups were formed: group 1 patients with symptoms of functional dyspepsia, including epigastric pain syndrome and postprandial distress syndrome; Group 2 - the study, without symptoms of functional dyspepsia.
В проведенном нами исследовании было выявлено снижение порога висцеральной чувствительности у обследуемых с симптомами функциональной диспепсии, о чем свидетельствует меньший объем выпитой жидкости в ходе всего эксперимента по сравнению со здоровыми. Также стоит отметить, что у данных пациентов более низкий порог температурной чувствительности, об этом говорит уменьшение объема выпитой жидкости при увеличении температуры воды почти на 60% по сравнению с исходной величиной (583,3 мл в 1-й день (температура воды 25°С) и 241,7 мл во 2-й день (температура воды 40°С).In our study, we revealed a decrease in the visceral sensitivity threshold in subjects with symptoms of functional dyspepsia, as evidenced by a smaller volume of fluid drunk during the entire experiment compared with healthy ones. It is also worth noting that these patients have a lower temperature sensitivity threshold, this is evidenced by a decrease in the volume of liquid drunk with an increase in water temperature by almost 60% compared to the initial value (583.3 ml on the 1st day (water temperature 25 ° C) ) and 241.7 ml on the 2nd day (water temperature 40 ° C).
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2020106681A RU2725197C1 (en) | 2020-02-12 | 2020-02-12 | Visceral hypersensitivity assessment method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2020106681A RU2725197C1 (en) | 2020-02-12 | 2020-02-12 | Visceral hypersensitivity assessment method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2725197C1 true RU2725197C1 (en) | 2020-06-30 |
Family
ID=71509886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020106681A RU2725197C1 (en) | 2020-02-12 | 2020-02-12 | Visceral hypersensitivity assessment method |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2725197C1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2774016C1 (en) * | 2021-06-28 | 2022-06-14 | федеральное государственное бюджетное образовательное учреждение высшего образования «Ижевская государственная медицинская академия» Министерства здравоохранения Российской Федерации | Method for diagnosing central sensitization in functional dyspepsia |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070082956A1 (en) * | 2003-07-28 | 2007-04-12 | Merz Pharma Gmbh & Co. Kgaa | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity. |
| RU2568850C2 (en) * | 2009-07-08 | 2015-11-20 | ГР ИНТЕЛЛЕКЧУАЛ РЕЗЕРВ, ЭлЭлСи | New gold nanocrystals for medical treatment and processes for electrochemical production thereof |
| RU2592283C2 (en) * | 2010-07-28 | 2016-07-20 | Грюненталь Гмбх | DERIVATIVES OF CIS-TETRAHYDRO-SPIRO(CYCLOHEXANE-1,1'-PYRIDO[3,4-b]INDOLE)-4-AMINE EFFECTIVE IN TREATING NEUROPATHIC AND/OR CHRONIC PAIN |
-
2020
- 2020-02-12 RU RU2020106681A patent/RU2725197C1/en active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070082956A1 (en) * | 2003-07-28 | 2007-04-12 | Merz Pharma Gmbh & Co. Kgaa | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity. |
| RU2568850C2 (en) * | 2009-07-08 | 2015-11-20 | ГР ИНТЕЛЛЕКЧУАЛ РЕЗЕРВ, ЭлЭлСи | New gold nanocrystals for medical treatment and processes for electrochemical production thereof |
| RU2592283C2 (en) * | 2010-07-28 | 2016-07-20 | Грюненталь Гмбх | DERIVATIVES OF CIS-TETRAHYDRO-SPIRO(CYCLOHEXANE-1,1'-PYRIDO[3,4-b]INDOLE)-4-AMINE EFFECTIVE IN TREATING NEUROPATHIC AND/OR CHRONIC PAIN |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2774016C1 (en) * | 2021-06-28 | 2022-06-14 | федеральное государственное бюджетное образовательное учреждение высшего образования «Ижевская государственная медицинская академия» Министерства здравоохранения Российской Федерации | Method for diagnosing central sensitization in functional dyspepsia |
| RU2804178C1 (en) * | 2023-01-13 | 2023-09-26 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ижевская государственная медицинская академия" Министерства здравоохранения Российской Федерации | Method for diagnosing delayed gastric evacuation in postprandial distress syndrome |
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