RU2677340C2 - Method of population recovery - Google Patents

Abstract

FIELD: medicine.SUBSTANCE: invention relates to preventive medicine and can be used for the recovery of the population. For this purpose, take the Living Chlorella microalgae concentrate in dose, depending on age, on an empty stomach 30 minutes before a meal, washing it down with water, or fresh juice, or dairy products, for 1–2 to 6 months.EFFECT: method allows to increase the health effect in treating patients with various diseases and reduce the risk of occurrence of mass-related diseases of the population due to the enhancement of the immune and protein-synthetic functions of the body.1 cl, 3 ex

Description

The invention relates to the field of food industry, in particular to the prevention and prevention of mass-related diseases using biologically active additives (BAA) as an additional special nutrition.

Food supplements from aquatic organisms are widespread. For example, the known preparation from the tissues of marine hydrobionts "Orbitar", used to increase human resistance to adverse environmental factors. (RF patent 2053779 A61K 35 \ 56)). Its disadvantage is the complexity of the composition and method of use.

Known dietary supplement containing soluble dietary fiber and biologically active substances of the sea urchin. (RF patent 2165719 A23L 1 \ 30).

Its disadvantage is the complexity of the composition and method of application.

A mass of biologically active additives based on microalgae is known, mainly chlorella and spirulina. For the first time, he proposed the use of water-soluble derivatives of chlorophyll for medical purposes for oral and intravenous administration of chlorine mixtures. At the same time, low toxicity of the drug, its hypotensive, antisclerotic, antispasmodic, analgesic, antirheumatoid effects were noted, which served as the basis for the use of water-soluble chlorins for the prevention and treatment of cardiovascular diseases, atherosclerosis, rheumatoid arthritis. (Pat 222742101 (02 \ 1942) USA \ E.G / Snyder \ Preparation of chlorine \}.

The disadvantage of the method of applying this method in its high cost.

A known technology for extracting from plant raw materials, in particular from Spirulina microalgae, a complex of biologically active chlorins containing chlorin e6 as a main component, the effect of which on the tumor is enhanced, and general pharmacological parameters are improved due to the natural chlorins contained in the complex, in particular chlorin with the ability to accumulate with high selectivity in neoplastic formations and abscesses. Taken together, this is the active substance of chlorins, which in the form of a 7% aqueous solution is the substance "Radachlorin" used for the preparation of various dosage forms, including dadachlorin solution for intravenous administration and radachlorin gel for external use.

(Reshetnikov A.V. “Photoimmunotherapy (FIT) as a direction of photodynamic therapy (PDT) \\ Advances in modern natural sciences. - 2007. - No. 6. - P. 93-98)

The disadvantage of the method of application of this dietary supplement in its high cost and complexity of use.

The objective of the invention is to increase the healing effect in patients with various diseases and reduce the risk of mass-related diseases of the population.

The problem is solved by clinical trials and experiments with patients with different pathological changes in clinical blood tests when they take the food concentrate "Living Chlorella" (strain IFRS No. 111).

Chlorella (lat. Chlorella vulgaris) is a unique unicellular green microalgae that has existed on Earth since ancient times and has survived major natural disasters. It was first discovered in 1890 by the Danish microbiologist M. Beyzhernik and began to be cultivated at the beginning of the last century as a rich source of protein. Chlorella is a biogenic immunostimulating drug, as well as a natural antibiotic that fights infectious, bacterial and other diseases. The immunostimulating properties of chlorella help restore, maintain and enhance the innate immunity of a person.

The composition of the algae contains a huge amount of chlorophyll - the green pigment of plants, with which they absorb the energy of sunlight and carry out photosynthesis. Chlorophyll enhances the body's immune function, accelerating photosynthesis. In addition, chlorophyll promotes the production of proteins that fight viruses, and also participates in the process of hematopoiesis.

In addition to chlorophyll, chlorella also contains vitamins C, E and beta-carotene, which is especially effective in enhancing immunity. Scientists have proven that chlorella contains at least 13 vitamins. Moreover, chlorella, in the amount of synthesized vitamins, surpasses all plant foods and crops, and even yeast. So, for example, vitamin B12, which is necessary for blood formation and DNA formation, is not found in yeast or in higher plants, and chlorella produces it.

Example 1 of the work of chlorella is one of the clinical trials conducted in 2003. In the course of these tests, chlorella was recommended for patients receiving the flu shot. Thus, the doctors wanted to make sure that taking this algae affects the improvement of the immune system functions. All patients older than 50 years were divided into two groups. Each of the groups, for one week before vaccination and three weeks after vaccination was given a means of immunity. In the first group, this was a placebo (a harmless substance prepared as a medicinal product that does not have any medicinal properties and has the effect of self-hypnosis of the patient). In the second, this tool was chlorella. After conducting clinical trials, doctors found that the patients of the second group of antibodies had 2 times or even 4 times more than the patients of the first.

The use of chlorella for the elimination of toxins, poisons, poisons, which lead to various types of intoxication, gave excellent results. Immediately after taking chlorella, a powerful cleansing of the body of toxins begins. Chlorophyll is one of the most effective means of cleansing the body.

In Japan, studies were carried out that revealed the amazing properties of chlorella: this algae removes heavy metals from the body, such as mercury, cadmium, lead and arsenic.

In Russia, the only product based on a living plant cell of chlorella microalgae in the form of a concentrate has been created; industrial biotechnology for the production of Living Chlorella concentrate for humans has been developed. As a result of initial studies (2008), the immunomodulating effect of the microalgae Chlorella vulgaris (strain IFRS No. 111) on the immunocompetent cells of all people participating in the experiment was established. Improving visual functions, neurophysiological and electrophysiological indicators by an average of 15-25% (Tumanova A.L. Experimental studies to study the effect of food suspension on the human body. \ International Journal of Applied and Basic Research. - 2011. - No. 9. - P. 85-88 \). A clinical blood test revealed an improvement in the blood picture by the following indicators: color indicator, platelets, lymphocytes, segmented, eosinophils, ESR in 68% of cases.

Food concentrate "Living Chlorella" was produced by Delo LLC, has a certificate of state registration of the Russian Federation. 77.99.88003.U.010343.11.15. dated November 24, 2015. In the process of photosynthesis, chlorella produces and releases more than 650 precious biologically active substances into its growth environment. When drying, a significant amount is lost, depriving the known dry chlorella of the most valuable. The created and patented technology allows you to grow and store living chlorella cells in the form of a saturated living concentrate.

The composition of the food concentrate "Living Chlorella" (No. 04-13 \ 16 Center for Chemical Research in Moscow on 04/04/16) (content in 100 g of dry matter) includes:

= Amino acids: lysine (5.31 g), arginine (7.95 g). histiline (1.5 g), alanine (4.61 g), isoleucine (2.16 g), leucine (4.48 g), serine (2.1 g), threonine (1.88 g.), glycine (3.74 g.), aspartic acid (4, No. g.), glutamic acid (5.13 g.), tyrosine (0.53 g.), methionine (0.96 g.) , proline (3.03 g), valine (3.4 g), cystine (0.49 g);

- Polyunsaturated fatty acids: linoleic (omega-6) (659.3 mg), linolenic (3042 mg, palmitic (612 mg), hexadecadiene (301.2 mg), hexadecatrienic (Omega-3) (166 mg);

- Fat-soluble vitamins: tocopherol (E) (5.1351 mg);

- Water-soluble vitamins: riboflavin B2 (1.1145 mg), pyridoxine B6 (0.0542 mg), ascorbic acid C (, 3675 mg), nicotinamide PP (0.2199 mg), folic acid B9 (0.5422 mg), pantothenic acid B5 (2.5 mg);

- Chemical elements: lithium, boron, sodium, magnesium, phosphorus, potassium, calcium, manganese, cobalt iron, chromium, nickel, etc.

Carry out the proposed method as follows. Take orally (adults from 16 years), 1 tablespoon on an empty stomach 1 time per day 30 minutes before meals in the first week, then 2 tablespoons of the concentrate from the second week. The concentrate is washed down with water or added to freshly squeezed juice or fermented milk products.

Children and adolescents (5 to 10 years old) take 1 teaspoon of the concentrate in the same way, and 11 to 15 years old take 1 dessert spoon of the concentrate in the first week and 1 tablespoon of the concentrate from the second week.

They take the concentrate seasonally from 1-2 to 6 months. Receptions can be repeated 2-3 times a year.

In 2016, an experiment with the intake of “Live Chlorella” food concentrate was carried out at the Department of Physiology, SIRUDN, NIMC “Ecology and Human Health”, Scientific Research Institute of Medical Primatology, Scientific Research Center for the Prevention and Control of AIDS in the city of Sochi, GBUZ AIDS Prevention and Control Center in Sochi.

We observed 40 patients with various pathologies who underwent the following examinations before taking the Living Chlorella concentrate before and after completing the intake of this microalgae. According to the already existing references in the world literature on the effectiveness of the use of chlorella-based products, the list of studies included: immunological blood tests - general immunogram, cellular immunity, total IgE indicator, general diagnostic biochemical analysis. Additionally, the group analyzed: bioelectrography (assessment of autonomic functions), endoecological assessment of the degree of contamination of the body based on the specialized iris-prediction study “Iris-sigma”, assessment of visual functions and neurophysiological parameters using color campimetry, data from electrophysiological studies, subjective sensations and data from objective examinations.

An intermediate analysis of the patient’s condition by deviations from the norm showed a tendency to improve after 15 days of taking a prophylactic dose of the Living Chlorella concentrate. (1 tablespoon on an empty stomach). Given the absence of complaints of any food discomfort when taking the concentrate, for patients with a significant deviation of diagnostic parameters from the norm, the dose of a single dose was increased to 40 ml. It was noted that all patients felt a “surge of energy”, increased performance, including intellectual, stabilization of blood glucose, blood pressure (with daily measurement using the express method with a glucometer and tonometer at home), increased appetite, but at the same time, satiety smaller amounts of food, in two cases, a weight loss of 3-4 kg in two weeks was noted.

Example No. 2: volunteer 1. - HIV infection stage 4B of secondary diseases during ART: fibrocavernous pulmonary tuberculosis in the phase of infiltration and decay of MDR, MBT +, candidiasis of the mucous membranes of the oropharynx, weight loss of more than 20%, moderate moderate clinical chronic hepatitis activity.

As a result of taking the “Live Chlorella” food concentrate (30 days), an increase in the parameters of cellular immunity to the norm or norm (T-lymphocytes, T-suppressors, T-helpers) was obtained, as well as parameters such as: platelets, monocytes, fasting sugar, such as creatinine, hemoglobin, ESR, segmented, total bilirubin decreased or increased to normal.

Example 3: volunteer 3. - recurrent herpetic infection (H. Simplecs 1-2). Result: hemoglobin returned to normal, such parameters as ACT, total cholesterol, alkaline phosphatase decreased to normal.

Already at the intermediate stage of evaluating diagnostic parameters, a rather high healing effect was obtained (in 78% of patients from the experimental group), confirming the available information on the effect of the food microalga Chlorella vulgaris on the human body. Confirmation of the improvement of the blood picture in biochemical studies in 93% of patients was normalized by most of the indicators according to the following indicators: color indicator, platelets, lymphocytes, segmented, eosinophils, ESR, cholesterol, blood sugar. However, it was noted that in isolated cases in 4 people (1%), against the background of an improvement in most indicators, some deterioration was noted (bilirubin, ACT, ALT). This group includes patients older than 55 years long suffering from diabetes mellitus and atherosclerosis. For example, indicators of total cholesterol from 8.7 mmol / L to 5.8 mmol after a monthly intake of Live Chlorella concentrate, blood sugar 10.4 mmol / L to 6.4 mmol / L after.

It was also noted that the additional methods analyzed in the group of examinees - bioelectrography (assessment of vegetative functions), endoecological assessment of the degree of (lymphatic and subcutaneous fat) contamination of the body, the degree of viral and infectious load based on specialized irido-diagnostic studies “Iris-sigma” and “Iridoscrin” , assessment of visual functions and neurophysiological indicators - by the method of color campimetry, data of electrophysiological studies showed a higher percentage of clinical ffektivnosti (improvement to 78-93%) compared to previous studies (2008 - improvement of 15-25%).

The obtained rather high healing effect, proved by the assessment of diagnostic indicators before and after taking the Live Chlorella concentrate, allows us to recommend this food product (BAA) for the prevention and reduction of the risk of mass-related diseases, especially for people who are prone to occupational hazards and have long been under difficult conditions (astronauts, submariners, polar explorers, athletes during training, etc.), as well as people living in environmental risk zones who have suffered spontaneous, in ennye action and manmade disasters after a special additional clinical nutrition.

It is also advisable to use this product in the diet to support the health of animals that are kept in nurseries and are subjected to experimental tests.

Claims (1)

A way to improve public health, including as a dietary supplement a product containing chlorin, characterized in that the patient takes on an empty stomach 30 minutes before a meal dosed, depending on age, a concentrate of microalgae “Live Chlorella”, washed down with water, or freshly squeezed juice, or sour milk products for 1-2 to 6 months seasonally.