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RU2507212C3 - Способ получения рекомбинантного пептида и полученный пептид - Google Patents

Способ получения рекомбинантного пептида и полученный пептид

Info

Publication number
RU2507212C3
RU2507212C3 RU2012111965A RU2012111965A RU2507212C3 RU 2507212 C3 RU2507212 C3 RU 2507212C3 RU 2012111965 A RU2012111965 A RU 2012111965A RU 2012111965 A RU2012111965 A RU 2012111965A RU 2507212 C3 RU2507212 C3 RU 2507212C3
Authority
RU
Russia
Prior art keywords
peptide
producing recombinant
produced
pro
recombinant peptide
Prior art date
Application number
RU2012111965A
Other languages
English (en)
Other versions
RU2507212C2 (ru
RU2012111965A (ru
Original Assignee
Общество С Ограниченной Ответственностью "Айвикс"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to RU2012111965A priority Critical patent/RU2507212C3/ru
Application filed by Общество С Ограниченной Ответственностью "Айвикс" filed Critical Общество С Ограниченной Ответственностью "Айвикс"
Priority to CA2868820A priority patent/CA2868820C/en
Priority to PCT/RU2013/000433 priority patent/WO2013151467A2/ru
Priority to PT137727764T priority patent/PT2876113T/pt
Priority to PL13772776T priority patent/PL2876113T3/pl
Priority to EP13772776.4A priority patent/EP2876113B1/en
Priority to DK13772776.4T priority patent/DK2876113T3/da
Priority to ES13772776T priority patent/ES2768300T3/es
Priority to BR112014023888-0A priority patent/BR112014023888B1/pt
Priority to US14/388,080 priority patent/US9409947B2/en
Priority to EP19206860.9A priority patent/EP3650457B1/en
Priority to IN8984DEN2014 priority patent/IN2014DN08984A/en
Publication of RU2012111965A publication Critical patent/RU2012111965A/ru
Publication of RU2507212C2 publication Critical patent/RU2507212C2/ru
Priority to IL234753A priority patent/IL234753B/en
Priority to US15/213,039 priority patent/US20170158735A1/en
Application granted granted Critical
Publication of RU2507212C3 publication Critical patent/RU2507212C3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (1)

  1. Пептид общей формулы A-Thr-Lys-Pro-Б-В-Г-Х, где А - 0, Б - Arg, В - Pro, Г - 0, X - ОН, где 0 - отсутствие аминокислотного остатка, со стимулирующей половую и сексуальную функции активностью.
RU2012111965A 2012-03-28 2012-03-28 Способ получения рекомбинантного пептида и полученный пептид RU2507212C3 (ru)

Priority Applications (14)

Application Number Priority Date Filing Date Title
RU2012111965A RU2507212C3 (ru) 2012-03-28 2012-03-28 Способ получения рекомбинантного пептида и полученный пептид
EP19206860.9A EP3650457B1 (en) 2012-03-28 2013-05-28 Method for producing a recombinant peptide and resultant peptide
PT137727764T PT2876113T (pt) 2012-03-28 2013-05-28 Método de produção de um peptídeo recombinante e do peptídeo resultante
PL13772776T PL2876113T3 (pl) 2012-03-28 2013-05-28 Sposób wytwarzania rekombinowanego peptydu i uzyskany peptyd
EP13772776.4A EP2876113B1 (en) 2012-03-28 2013-05-28 Method for producing a recombinant peptide and resultant peptide
DK13772776.4T DK2876113T3 (da) 2012-03-28 2013-05-28 Fremgangsmåde til fremstilling af et rekombinant peptid og resulterende peptid
CA2868820A CA2868820C (en) 2012-03-28 2013-05-28 Method for producing recombinant peptides and resultant peptides with sexual-function stimulating activity
BR112014023888-0A BR112014023888B1 (pt) 2012-03-28 2013-05-28 Composições farmacêuticas compreendendo peptídeos recombinantes, usos de peptídeos recombinantes para estimular a função sexual e reprodutiva e para o tratamento curativo ou profilático de uma disfunção reprodutiva ou sexual e métodos não terapêuticos para estimular a função sexual ou reprodutiva
US14/388,080 US9409947B2 (en) 2012-03-28 2013-05-28 Method for producing a recombinant peptide and resultant peptide
PCT/RU2013/000433 WO2013151467A2 (ru) 2012-03-28 2013-05-28 Способ получения рекомбинантного пептида и полученный пептид
IN8984DEN2014 IN2014DN08984A (ru) 2012-03-28 2013-05-28
ES13772776T ES2768300T3 (es) 2012-03-28 2013-05-28 Método para producir un péptido recombinante y péptido resultante
IL234753A IL234753B (en) 2012-03-28 2014-09-21 A method for preparing a recombinant peptide and the prepared peptide
US15/213,039 US20170158735A1 (en) 2012-03-28 2016-07-18 Method for producing a recombinant peptide and resultant peptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2012111965A RU2507212C3 (ru) 2012-03-28 2012-03-28 Способ получения рекомбинантного пептида и полученный пептид

Publications (3)

Publication Number Publication Date
RU2012111965A RU2012111965A (ru) 2013-10-10
RU2507212C2 RU2507212C2 (ru) 2014-02-20
RU2507212C3 true RU2507212C3 (ru) 2022-05-04

Family

ID=49301137

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2012111965A RU2507212C3 (ru) 2012-03-28 2012-03-28 Способ получения рекомбинантного пептида и полученный пептид

Country Status (12)

Country Link
US (2) US9409947B2 (ru)
EP (2) EP2876113B1 (ru)
BR (1) BR112014023888B1 (ru)
CA (1) CA2868820C (ru)
DK (1) DK2876113T3 (ru)
ES (1) ES2768300T3 (ru)
IL (1) IL234753B (ru)
IN (1) IN2014DN08984A (ru)
PL (1) PL2876113T3 (ru)
PT (1) PT2876113T (ru)
RU (1) RU2507212C3 (ru)
WO (1) WO2013151467A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2507212C3 (ru) * 2012-03-28 2022-05-04 Общество С Ограниченной Ответственностью "Айвикс" Способ получения рекомбинантного пептида и полученный пептид
RU2626002C1 (ru) * 2016-10-24 2017-07-21 Общество С Ограниченной Ответственностью "Айвикс" Новая группа пептидов для лечения женской сексуальной дисфункции
RU2655763C2 (ru) 2016-10-24 2018-05-29 Общество С Ограниченной Ответственностью "Айвикс" Фармацевтическая композиция и способ лечения женских сексуальных дисфункций
RU2709503C1 (ru) * 2019-05-23 2019-12-18 Акционерное общество "Инновационный научно-производственный центр "Пептоген" (АО "ИНПЦ "Пептоген") Применение пептида thr-lys-pro-arg-pro-gly-pro (селанк) для повышения резистентности организма к острой гипотермии

Family Cites Families (17)

* Cited by examiner, † Cited by third party
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US3778426A (en) * 1970-12-16 1973-12-11 Research Corp Therapeutically useful polypeptides
RU1124544C (ru) * 1983-06-30 1995-01-09 Институт молекулярной генетики РАН Гептапептид, обладающий свойствами психостимулятора пролонгированного действия с иммунотропной активность
RU2058791C1 (ru) 1989-01-11 1996-04-27 Государственное предприятие "Элер-микро" Стимулятор репродуктивной способности у теплокровных животных
US5872100A (en) 1990-05-11 1999-02-16 Deghenghi; Romano Peptides containing D-2-Alkyl-Tryptophan
WO1994022460A1 (en) 1993-04-05 1994-10-13 University Patents, Inc. Diagnosis and treatment of erectile dysfunction
US5932548A (en) 1998-06-03 1999-08-03 Deghenghi; Romano Lysine containing peptides for treatment of heart disease
RU2155065C1 (ru) 1999-04-23 2000-08-27 Институт молекулярной генетики РАН Анксиолитическое средство и фармацевтическая композиция анксиолитического действия
US6211156B1 (en) 1999-11-10 2001-04-03 Asta Medica A.G. Peptides for treatment of erectile dysfunction
RU2252779C1 (ru) 2003-09-23 2005-05-27 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Способ профилактики и лечения язв желудочно-кишечного тракта
RU2290195C1 (ru) 2005-04-21 2006-12-27 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Средство с антикоагулянтной, антитромбоцитарной, антитромботической, фибриндеполимеризационной и фибринолитической активностями
CN101302246B (zh) 2007-05-09 2011-05-11 中国人民解放军军事医学科学院毒物药物研究所 黑色素皮质激素受体七肽类激动剂及其制备方法和用途
RU2010114001A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение пептида в качестве терапевтического средства
US7618801B2 (en) 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
RU2411249C2 (ru) * 2008-12-11 2011-02-10 Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН) Средство против вирусов: энцефаломиокардита, гриппа а, простого герпеса 2
RU2404793C1 (ru) * 2009-06-04 2010-11-27 Общество с ограниченной ответственностью Био Пептид Стимулятор половой, сексуальной и репродуктивной функции
EA200900804A1 (ru) * 2009-06-08 2010-08-30 Общество С Ограниченной Ответственностью "Витанта" Средство, активирующее половую функцию
RU2507212C3 (ru) * 2012-03-28 2022-05-04 Общество С Ограниченной Ответственностью "Айвикс" Способ получения рекомбинантного пептида и полученный пептид

Also Published As

Publication number Publication date
PL2876113T3 (pl) 2020-06-15
CA2868820A1 (en) 2013-10-10
IL234753B (en) 2018-11-29
EP2876113B1 (en) 2019-11-06
US20170158735A1 (en) 2017-06-08
IN2014DN08984A (ru) 2015-05-22
PT2876113T (pt) 2020-02-03
DK2876113T3 (da) 2020-02-03
WO2013151467A3 (ru) 2014-01-09
ES2768300T3 (es) 2020-06-22
BR112014023888A2 (pt) 2018-05-29
WO2013151467A2 (ru) 2013-10-10
US9409947B2 (en) 2016-08-09
RU2507212C2 (ru) 2014-02-20
RU2012111965A (ru) 2013-10-10
US20150111837A1 (en) 2015-04-23
BR112014023888B1 (pt) 2021-12-07
EP3650457B1 (en) 2021-03-17
EP2876113A2 (en) 2015-05-27
CA2868820C (en) 2021-09-21
EP3650457A1 (en) 2020-05-13
EP2876113A4 (en) 2017-03-01

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Legal Events

Date Code Title Description
HE9A Changing address for correspondence with an applicant
MM4A The patent is invalid due to non-payment of fees

Effective date: 20150329

NF4A Reinstatement of patent

Effective date: 20151220