RU2407682C2 - One-way valve system sealed over entire surface and fluid feed system - Google Patents

Abstract

FIELD: transport, package. ^ SUBSTANCE: proposed valve system comprises fluid source with bore and valve system communicated with said bore. Note here that valve system consists of inner core, tubular flexible membrane and casing. Note also that said core has fluid substance inlet bore and at least one outlet bore. Tubular flexible membrane has first and second ends, the former being thicker than the latter. Besides, said tubular flexible membrane is arranged above the inner core outer surface. Pressure acts on fluid to force it out through outlet bore to expand membrane outward from inner core outer surface. Casing covers flexible membrane and has outlet bore to feed fluid from valve system when pressure acts to fluid. Note here that with pressure released, first end of tubular flexible membrane comes in close contact with inner core outer surface before tubular membrane remaining part returns to close contact with inner core outer surface. ^ EFFECT: preventing oxygen passage or other impurities from ambient air into container via valve. ^ 42 cl, 11 dwg

Description

FIELD OF TECHNOLOGY

This invention relates to a distribution system and a supply system, and includes a single-acting, hermetically sealed valve, for supplying a sterile fluid substance, which may include a protective agent or be without a protective agent to prevent contaminants from entering the fluid substance. The distribution and supply system includes, for example, a valve that is surrounded by an elastic element that can carry pressure, or an elastomeric element to supply a fluid substance to the outlet, while at the same time preventing back flow into the source of the fluid substance after extruding the necessary portion of the fluid substance .

BACKGROUND OF THE INVENTION

Previously, to squeeze out a fluid substance without contaminants, anticoagulants were mixed with a fluid substance in a reservoir from which it was subsequently squeezed. The use of anticoagulants harms those who use the drug and often limits the effectiveness of the ingestion of a fluid substance, especially when the substance is a pharmaceutical substance, such as eye drops, intranasal preparations, cosmetic substances or skin care products. This group of drugs and other drugs is often sold with protective agents in many doses. The fluid substance may also be food, drinks, nutraceuticals and medicinal products.

Another characteristic feature is the ability of the valve to pass a certain amount of fluid substance into the outlet, while not causing any harm to the user, for example, when applying eye drops.

Flexible membranes used to be used to control the flow of fluid substance to the valve outlet, while preventing any other substances from returning to the vessel from which the fluid substance was discharged. However, valves such as those described in the proposed US patent number RE34,243 describe the use of gaskets together with a flexible membrane of uniform thickness for complete sealing. Other valve devices were used in the form of cylindrical parts, for example, when a flexible membrane slid under pressure along the straight side of the core while passing fluid, while preventing rapid ejection. Therefore, such a mechanism as an efficiently designed valve, through a high-performance process and the ability to reduce the manufacturing price by reducing the number of components and the possibility of using huge manufacturing capacities, was not previously provided.

SUMMARY OF THE INVENTION

According to an example of the present invention, the supply system accompanies a fluid substance from a sealed source, such as a flattenable container, and at the same time prevents any return of oxygen or other contaminants from the surrounding atmosphere through the valve and directly into the source with the fluid substance after a portion this substance has been issued.

A collapsible container may be of the type bellows, tube, inner pouch, or any other shape designed to provide almost all of its contents. Referring to an example of the present invention, the distribution exhaust system has a normal outlet for ejecting the required amount of fluid from the valve. The tank is carefully sealed with a valve so that no foreign substances get into it during the extrusion of the liquid.

The delivery of fluid substance occurs after pressure is applied to the reservoir so that the contents of the reservoir exit through the valve. The contents of the reservoir may be a pharmaceutical substance, such as eye drops, or another substance that other substances must not enter during the substance leaving the reservoir. Referring to an example of the present invention, a plurality of discharged liquid can be achieved by holding the reservoir of fluid substance in a compressed position. Other fluid substances without the use of preservatives include food, water, juices, cosmetics, or other fluid substance, which is supposed to be stored without foreign particles, despite repeated use of the product. The reservoir with fluid substance is protected by the housing so that it cannot be accidentally pressed.

The valve consists of an axially elongated inner core, which is located opposite the opening of the container with a fluid substance and is made of liquid plastic. The inner walls may have a connecting tube for the passage of fluid substance from the reservoir. At least one hole that passes through the connecting tube can provide a flow of substance from the inner core. The inner core may have a shape tapered at the end or a cone shape.

The axially elongated flexible membrane adheres tightly to the inner core and completely closes the passage at the end of the reservoir, which passes through the inner core. The flexible membrane ejects the contents from the inner core to the outside when pressure is applied to the fluid substance and it passes through the tube to the exit of the flexible membrane. The flexible membrane is designed in such a way that it is thicker at the end that is closer to the tank, since the flexible membrane is not the same thickness over the entire surface. This thickness allows the valve to be sealed with the side that will be thicker. As an alternative, even if the membrane was the same thickness, the elasticity of the membrane can change, since the outlet on the valve is less elastic, which allows the outlet on the valve to close first.

In the application, the flexible membrane and the inner core have a shape that tapers at the end into a conical shape, which allows a quick discharge function or holding the flexible membrane around the inner core.

The valve housing is located on the outside, at the end of the flexible membrane, near the adjustable outlet. A fluid substance that lends itself to pressure passes through the outer walls of an elongated flexible membrane and flows directly to the outlet through the outer surface of the inner core. The outlet adjusts the amount of fluid flow through. The top cap covers the valve cover to protect the valve during extrusion. The sleeve can be attached to the valve and reservoir to provide greater sealing, and to make sure that no foreign particles get inside. The sleeve and part of the neck of the tank are made with a closing mechanism so that the sleeve can be adjusted during the passage of fluid, and at the same time prevent opening and depressurization of the tank, which can lead to contamination of the tank.

Various signs of novelty that characterize the invention are described in detail in the claims, which is attached and is part of the description. For a better understanding of the invention, its work, advantages and special tasks that are achieved when using it, reference should be made to the accompanying drawings and a descriptive part, which illustrates and describes the best use of the invention.

BRIEF DESCRIPTION OF THE DRAWINGS

Figure 1 is an axially-elongated view of the feed system according to this invention.

FIG. 2A is a view of the supply system shown in FIG. 1 according to the present invention.

FIG. 2B is a view of the delivery system shown in FIG. 1 according to the present invention, which also includes a pump for supplying a fluid substance.

Figure 3 is a view of the soft end and the outlet according to this invention, where the outlet is shown in longitudinal section.

Fig. 4A is an enlarged axially-elongated partial view of a sealed over the entire surface of a one-way valve with a flat end according to this invention.

Fig. 4B is an enlarged partial axial-elongated view of an all-surface sealed one-way valve with a rounded soft end according to this invention, where the one-way valve system is inoperative.

Fig. 4C is an enlarged partial axial-elongated view of the entire surface of a one-way valve with a rounded end according to this invention, where the one-way valve system is operational.

Fig. 4D is an enlarged partial axial-elongated view of an all-surface sealed one-way valve, in which the inlet at the soft end comprises a flexible membrane and an inner valve core according to this invention.

Fig. 5 is an enlarged partial axial-elongated view of a one-way valve sealed over the entire surface, as shown in Fig. 4B and Fig. 4C according to an example of the present invention.

6A is an axially-elongated partial view of a one-way valve sealed over the entire surface with an inlet and an outlet in accordance with an example of the present invention.

6B is an enlarged partial axial-elongated view of a one-way valve sealed over the entire surface with an inlet and an outlet in accordance with an example of the present invention.

DETAILED DESCRIPTION OF THE INVENTION

As shown in FIGS. 1, 2A and 2B, the distribution and exhaust system 1 in this example of the invention consists of a reservoir or source, such as a bellows 2, which is located inside the housing 6. The housing 6 for the fluid substance that was originally sterilized, and the valve 3 (which 2A, 2B and 4A-D) are intended to supply fluid substance from a reservoir 2 to an outlet when pressure is applied to the reservoir 2 or to the outlet mechanism 2a that is connected to the reservoir 2. The cap 15 closes the valve 3 in order to prevent contaminants 3 from entering the valve and to store the tank. The housing 6 has a surface 6a for holding the drug. The sleeve 8 is attached to the valve 3 and to the tank 2, while providing a hermetic closure, and eliminates the possibility of contaminants entering the tank 2.

As shown in FIGS. 1, 2A and 2B, reservoir 2 is long enough to allow several doses of a substance to pass directly from the reservoir, and this occurs when pressure is applied to the reservoir. Other reservoirs, such as soft tubes or spray cans, that hold a certain amount of fluid substance can also be used. Valve 3 and sleeve 8 initially prevent air or other substances from entering the reservoir, which may interfere with the passage of the substance.

As shown in FIGS. 1, 2A and 2B, a reservoir or bellows type source 2 is laterally connected by an axially elongated housing 6 to prevent possible compression of the reservoir with the liquid. An axially elongated recess 6b in the housing 6 allows the user to access the trigger mechanism 2a of the reservoir in which the fluid substance is under pressure. The housing 6 has a surface 6a so that the housing opens when the fluid exits under pressure.

As shown in FIGS. 2A and 2B, the valve system 3 has a valve case 14 that covers the flexible membrane 13. The valve system 3 consists of an inner core 10, an axially elongated closed passage 11, an inlet / outlet 12, a flexible membrane 13, a casing 14 a flange valve 14a and a soft cap 7 with an outlet 7a (described in more detail below with reference to FIGS. 4A-D). While the flexible membrane 13 is in the position of contact with the inner shell 10, then, when a certain fluid passes, it is filled together with the inner shell 10 with this substance, so that there is not a single empty space when the valve system is completely extruded.

The axially directed valve housing 14, which is adjacent to the tank 2, has a circular outwardly directed flange 14a, which is opposite the flange at the end of the flexible membrane, providing sealing for the valve body at the outlet of the container 2. The lateral neck of the tank 2 is secured by a flange 14a, for example, sleeve 8 with a screw thread on their respective sides. Alternatively or in addition to this, the sleeve 8 and the opening side neck of the tank 2 are connected to a mechanism that is capable of loosening to pass fluid substance, while at the same time preventing the sleeve 8 from unscrewing and opening the system. This prevents unintended contamination and prevents the tank from being refilled with consistency.

As shown in FIG. 2B, in a suitable structure for pumping a fluid substance, the pumping system 16 is connected to the valve 3a, to the tank 2 and to the vessel 6b. A sleeve 8 connects the pumping system 16 and the valve 3a. The pumping system 16 is connected to the vessel 6b using a screw thread. The neck of the vessel 6b closes the pumping system 16 with a screw thread, which compresses the pumping system 16 with a sealing flange 2c of the tank 2 between the vessel 6b and the pumping system 16. Alternatively or in addition, the sleeve 8 and the opening neck of the vessel 6b are designed to be closed, which allows hold down the pumping system 16 and exit to the system. This prevents unintended contamination and prevents the tank from being refilled with consistency.

The pumping system 16 is connected to the valve system 3a, which has a trigger 17, an inner shell 10, an axially elongated closed passage 11, an inlet / outlet 12, a flexible membrane 13, a valve housing 14 with a sleeve 14a, and a soft cap 7 with an outlet 7a ( described in more detail below with reference to FIGS. 4A-D). The trigger 17 may be attached or include a spray. In operation, the nebulizer 17 serves to directly discharge a fluid substance from the reservoir 2 directly through a valve of a one-way type pumping system 16, causing the required amount of a certain liquid to come out. For example, conventional pumps can thus be used.

Moreover, the reservoir 2 can be connected from the inside of the vessel 6b, the end of which is clamped by a sleeve 2c. The sleeve 2c serves to protect the tank 2 from the possibility of damage, breaks or the unforeseen possibility of applying force to the tank 2.

As shown in FIG. 3, the adjustable outlet 7a is a mechanism of intersecting slots, which basically allows fluid substance to be sprayed from the reservoir in which it is located. This mechanism causes the outlet 7a to close independently after the pressure on the reservoir of fluid substance has ceased.

The adjustable outlet 7a can be made as necessary in order to bring the flow of fluid substance from the reservoir in which it is located to the outside. Alternatively, when selecting the required power to be applied to the outlet 7a, it is possible to pass the necessary amount of fluid substance, for example, if it is an eye drop. If it is necessary to release more fluid substance, the outlet 7a may be designed in such a way as to allow the release of more liquid matter.

4A-D, the valve 3 initially has an inner core 10, an axially elongated passage 11, an inlet / outlet 12, a flexible membrane 13, a valve housing 14 with a gasket 14a, and a soft end 7 with an outlet 7a. The cover 15 is located on top of the valve system 3 when it is not used, performing the function of protecting against possible contaminants.

Inside the valve 3, the axially elongated inner shell 10 fits snugly against the reservoir 2 so that the flow from the reservoir enters the axially elongated passage 11 in the inner core. This passage 11 is located along the entire axial surface of the inner core. About halfway through this passage 11, the inner core has two outlets 12 that are transverse to the tube from its inner surface to the outer surface of the inner core 10. The inner core 10 is made of liquid plastic and terminates inside the valve outlet. Moreover, in these exemplary embodiments, no air is present inside the container inside the closed passage 11 and the outlets 12. Additional outlets 12 may be located on the surface of the inner core 10.

Moreover, in these examples, the inner core 10 and the flexible membrane 13 are made in such a way that they fit snugly against each other, for example, their tight fit is ensured by an air-tight plug located between the flexible membrane 13 and the inner core 10. In the following the examples shown, the method of forming a flexible membrane 13 and the inner core 10 as well as other devices that are necessary to seal one element with another is an asymmetric process, which One creates a perfectly flat surface at the contact points where it is necessary that one element is adjacent to another. Accordingly, in this example, the location of the parts too close, for example the outer core 10, the flexible membrane 13 and other parts, is used for sealing and further functioning of the valve.

A flexible membrane 13, which has high elasticity, fits snugly against the outer surface of the inner core and extends from the beginning of the reservoir 2 to the opposite side of the inner core 10. As shown in FIGS. 4A-D, the thickness of the membrane is different along the axial passage. In the area of the inner core exit, the axial extension is much wider than in the remaining part of the membrane 13. This is because the rim is not axially separated by axial incisions. The thicker end, after the valve discharges the liquid, closes the valve on the side closer to the opening 7a, while preventing any backflow. All this is done with thick walls that provide more pressure. As a result, the flexible membrane 13 has an uneven pressure.

In one embodiment, the thickness of the membrane can vary along the surface of the axis, and the place that surrounds the exit side of the inner core is much thicker than the rest of the membrane. 13. Moreover, in some designs, the rim is not separated from the axial passage by notches. The elasticity of the end of the flexible membrane, which is closer to the valve, may vary, for example, may decrease so that the end that is closer to the valve closes first after the pressure on the vessel has ceased.

In other embodiments, the flexible membrane 13 and the inner core 10 are significantly narrowed and tapered at the end of the outlet 7a so that the inner core 10 is pressed against the flexible membrane 13 during rapid assembly using automated equipment.

At the end, which is adjacent to the outlet of the reservoir 2, the flexible membrane 13 has an outwardly directed flange, which is located opposite the flange of the inner core located at the outlet of the reservoir.

An axially directed valve housing 14 covers the flexible membrane 13 and, as shown in the rest position in FIG. 2A, is located around the outer circumference of the flexible membrane. The end of the valve casing 14, which is adjacent to the tank 2, has a round outwardly directed flange 14a, which is opposite the flange at the end of the flexible membrane, providing sealing for the valve body at the outlet of the container 2.

The valve housing 14 is formed from an inner layer of plastic material that extends from its flange 14a and around the outlet side of the valve 3. The plastic material forms a soft end 7 around the exit side of the valve housing 14, which is a great advantage when the valve is used for eye drops . Such a soft end 7 prevents possible but undesirable damage to the sensitive retina or other tissues of the eyeball. The soft end 7 has an outlet 7a for passing fluid substance. The outlet is in the closed position, except for those moments when it is necessary to release a fluid substance.

As shown in FIGS. 4A-D and FIG. 5, various designs of the valves 3 also have different designs of the soft end 7, as described below.

As shown in FIG. 4A, a valve is created that has a smooth soft end 7. The soft end 7 has a smooth surface that allows less fluid substance to pass to the outlet 7a, since the smooth surface ends at the outlet 7a, which is shorter. The soft end 7 has an outlet 7a, which is designed so that it is possible to withdraw a stream of fluid substance from the reservoir. Moreover, the outlet 7a may have a cross sectional shape, as shown in FIG. 3. When selecting the outlet 7a, the desired amount of fluid substance should be sprayed out, for example, when eye drops or other drops need to be released in a certain dose. If more fluid substance needs to be discharged, then the outlet 7a may be formed so as to discharge a larger amount of the necessary liquid, which can be achieved with a larger diameter of the opening.

As shown in FIGS. 4B-C, a valve is created that has a round soft end 7. The soft end 7 has a rounded end, which is especially effective when it is necessary to instill fluid substance into the eyes and surrounding soft tissue or other sensitive areas of the body. Since there are no sharp corners in the rounded-off device, any possibility of harming the eye or other sensitive parts is excluded, which can happen if the fluid is handled carelessly. The soft end 7 has an outlet 7a, which is designed to squeeze a certain amount of fluid substance. Moreover, the outlet 7a may have transverse cuts, as shown in FIG. 3. When selecting the outlet 7a, the desired amount of fluid substance should be sprayed out, for example, when eye drops or other drops need to be released in a certain dose. If you want to release a larger amount of fluid substance, then the outlet 7a can be formed so as to release a larger amount of the required fluid, which can be achieved with a larger opening diameter.

As shown in FIG. 4D, a valve is created that has a soft end 7 with an elongated version of the outlet 7a. An elongated version of the outlet 7a has the ability to fit the inner core 10 and the flexible membrane 13, and is used to pass a viscous substance, such as lotion, cream and emollients, but can also be used for ordinary fluid substance. An elongated version of the outlet 7a allows you to squeeze out a fluid substance without having to pass through two holes, namely the holes at the end of the flexible elastomer 13 and the outlet 7a.

As shown in FIG. 5, where it is easier to see the gap that is formed between the inner core 10 and the flexible membrane 13 under fluid pressure that passes through the outlet 12. The outlet 7a of the soft end 7 can evenly pass fluid or be used as described above.

As shown in FIGS. 6A-B, in another design, the fluid substance passes through one outlet 12 in the inner core 10 and expands the flexible membrane 13, circulating around the outer part of the inner core 10, and exits through the outlet 12a, as shown in FIG. 6A and 6B. This leads to the need for less pressure to squeeze out the fluid substance and is particularly advantageous for using the fluid substance in a viscous form, such as lotions, creams or moisturizers. It should be noted that additional outputs 12 can be located on the entire surface of the inner core 10.

In this example, when it is necessary to squeeze out the required amount of fluid substance, it is necessary to remove the outer end 15 and press on the actuation device 2a of the tank 2 so that the required amount of fluid substance leaves the tank and enters the passage 11 in the inner core 10. The substance flows through passages 12 and expands the flexible membrane 13 along its circumference and flows directly to the exit of the flexible membrane and then enters the outlet 7a, where it is extruded at the end.

When the extruded fluid substance passes the end of the flexible membrane, it flows directly over the entire surface to the outlet 7a, which then opens and passes the substance through the valve. When the fluid substance is squeezed out and pressure is no longer applied to the vessel, the outlet 7a closes, blocking any return to the valve. The top cover 15 is located on the valve system 3 when not in use, while preventing any contact with surrounding contaminants.

In another design, as shown in FIGS. 6A and 6B, for example, a fluid substance passes through one outlet 12 in the inner core 10 and expands the flexible membrane 13, circulating on the outside of the inner core 10 and exiting through the outlet 12a, as shown in 6A and 6B. This leads to the need for less pressure to squeeze out the fluid substance and is especially beneficial when using the fluid substance in a viscous form, such as lotions, creams or moisturizers.

By stopping the pressure on the acting device of the tank 2a, the liquid exit function is completed, and the flexible membrane 13 returns to its previous position and abuts against the outer surface of the inner core 10. The reverse movement of the flexible membrane begins near the external outlet due to its increased thickness and allows smooth joining with the external the surface of the inner shell, while returning the fluid substance through the outlets back into the tank, while preventing the ingress of contaminants. Squeezing out the necessary portion of fluid substance can continue until the reservoir is completely empty. As a result of the structure and operation of the valve, as shown in this example, the valve provides constant pressure on the contained components by sealing a fluid substance.

In yet another example, for example, in a spray can, as shown in the example of FIG. 2B, the drive device 17 serves to transmit force to the pump device 16 when it is necessary to squeeze out the substance. This in turn compresses the reservoir 2, thereby exposing the necessary efforts to open the valve 7a, for the exit of the fluid substance.

Elastomers that are capable of forming a soft end 7, a flexible membrane 13, and a valve cover 14 in this example include heat-resistant elastomers such as Dinaflex, which is manufactured by GLS, C-Flex, which is manufactured by CPT, or Santopren, which is manufactured by " Advanced Elastomer Systems, Inc. " . Elastomers or materials that contain other similar substances may have substances designed to protect against bacteria; it can be silver ions contained within the ceramic carrier, supplied, for example, by AgION, or slowly released silver ion compounds, supplied, for example, by Westlake Plastic Technologies, which are used to create antimicrobial components. Moreover, other antimicrobial components may also be used. Moreover, the soft end 7, or the flexible membrane 13, or both elements together could be positively charged in order to protect the fluid substance, and be covered, for example, with Teflon plastic, or have a moisture resistant coating or other other system for keeping the fluid substances.

In other designs, including those described above, the elastomer durometer may have a different shape depending on the varying viscosity of the fluid substance. For example, vessels containing drugs that have a relatively high viscosity will be used more gently to reduce the force required to squeeze out a fluid substance, while vessels containing drugs that have a relatively low viscosity will be used more heavily for in order to increase the force required to squeeze out a fluid substance. Similarly, fluid substances that contain lubricants will also be used more strongly to ensure that the substance passes through the hole normally.

As mentioned above, parts of the dispensing and discharging device, including, including the valve, can be assembled to ensure reliable hermetic isolation, and thereby providing optimal sealing and operation of the device.

A variety of pharmaceutical, cosmetic, nutritious and other liquid preparations can be used when they need to be protected from surrounding pollutants. The flow characteristics of the preparation to be squeezed out determine, or at least can affect, the selection of the desired valve.

In this example, the material of the outlet 7a does not absorb fluid substance. As a result, the substance, falling into the outlet 7, leaves the dispenser and does not fall back into the space between the inner core and the flexible membrane, thereby ensuring the purity and sterility of the substance remaining in the vessel.

It should be understood that the various valve designs described above can only be used individually to completely release the required fluid substance.

As mentioned above, the flowing substances may be pharmaceutical, cosmetic, nutraceuticals, eye drops or other ophthalmic substances, dermatological and gynecological preparations, as well as preparations for treating dermatological and pulmonary diseases or preparations related to the mucous membrane; food products such as daily foods, water and juices; cosmetic preparations, such as cream for skin care or toiletries; liquid vitamins - all of them must be protected from the possibility of the ingress of surrounding pollutants when consumed, as well as when storing them in a tank 2.

According to exemplary constructions of the present invention, many existing products for sale that contain anticoagulants can be reformulated to those that do not contain them and used for multiple use with the valve and outlet of the present invention. For example, conventional creams, emollients, eye drops, nasal sprays, cosmetic creams that need anticoagulants, para-aminobenzoic acids and benzalkonium chloride, which are harmful substances, can be reformulated as those that do not include anticoagulants needed for storage and the use of a one-way valve system according to the invention. This can be achieved by changing the formulation of the product relative to its natural formulation, without adding other means to the formulation by changing the shape of the filler. Therefore, such natural products are adapted for storage and consumption using the one-way valve system according to the invention, since their formulation is completely pure from additives.

The following examples provide structures that describe the category of medications that are suitable for storage and use with this one-way valve system. This kind of storage and use can also be provided for natural products for multiple use, as disclosed in US patent No. RE 34243, and US patent No. 5092855; 5,305,783; 5,279,447; 5,305,786; and 5353961, which are incorporated by reference.

EXAMPLES

Example 1

In this example, ophthalmic preparations that do not contain antiseptics are adapted for storage and use with a one-way valve system with a delivery system. For example, drops for the eyes, and especially those drops that are necessary for chronic eye diseases, such as glaucoma, allergies or inflammation, and those medicines that are simply needed during, for example, eye operations, they are suitable for storage and use with one-way valve system with feed system. In a further example, those preparations for the eyes that are used to alleviate visual fatigue, or to eliminate pain caused by prolonged exposure to a computer or television or simply fatigue, are adapted for storage and use using a one-way valve system with a delivery system.

Examples of preparations for eliminating dryness in an eyeball may include methyl cellulose, hyaluronic acid, polyethylene ethylene glycol 400 0.4%, propylene glycol 0.3%, glycerin, or mineral oils. Glaucoma preparations contain timolol maleate 0.25% / 0.50%, essential acids 0.1%, bimatoprost 0.03% and grass simple 0.004%. Allergy medications contain 0.1% hydrochloride and 1% prednisoline ether. Anti-inflammatory drugs contain ketorolac 0.5% and diclofenac 0.1%.

Example 2

In this example, otolaryngological preparations that do not contain antiseptics are adapted for storage and use with a one-way valve system with a delivery system. For example, nasal preparations and necessary nasal sprays, ear care cream, ear drops, hormonal ear drops, antibiotics, nose drops, and nose drops that contain 0.25% phenylephrine and 30 mg pseudoephedrine are suitable for storage and use with a one-way valve system with a feed system.

Example 3

In this example, dermatological preparations that do not contain antiseptics are adapted for storage and use using a one-way valve system with a delivery system. For example, natural preparations; preparations for the care of the scalp; corticosteroid creams, lotions and ointments; basic antibiotics and antifungal drugs, adapted for storage and use with a one-way valve system with a feed system. They are adapted for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

Example 4

In this example, preparations intended for the treatment of dermatological diseases that do not contain antiseptics are adapted for storage and use with a one-way valve system with a delivery system. For example, natural preparations for the skin; preparations for the scalp; corticosteroid creams, lotions and ointments; basic antibiotics and antifungal drugs; therapeutic skin creams that contain antibacterial, antiparasitic substances, creams that prevent dermatitis, as well as moisturizers, are suitable for storage and use with a one-way valve system with a delivery system, because they are prepared on a natural basis.

Example 5

In this example, preparations intended for the treatment of anorectal diseases that do not contain antiseptics are adapted for storage and use using a one-way valve system with a delivery system. For example, natural creams, painkillers, helium lubricants or other drugs for the treatment of hemorrhoids, are adapted for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

Example 6

In this example, preparations intended for the treatment of pulmonary diseases that do not contain antiseptics are adapted for storage and consumption using a one-way valve system with a delivery system. For example, natural-based drugs to prevent airway difficulties, such as nebulizers that contain an adrenaline-like substance, an anticholinergic, a corticosteroid hormone, and a reusable theophylline drug, are suitable for storage and use with a one-way valve system with a delivery system, because they are cooked on a natural basis.

Example 7

In this example, gynecological preparations that do not contain antiseptics are adapted for storage and use with a one-way valve system with a delivery system. For example, vulvovaginal preparations, such as those with an anti-irritant base or for allergic vulvitis, painful feelings, bacterial vaginosis, treatment of vaginal inflammation, containing all azoles and nystatin, butoconazole 2%, clotrimazole 1%, metronidazole and a drug against trichomonas colpitis, are suitable for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

Example 8

In this example, lens preparations that do not contain antiseptics are adapted for storage and use with a one-way valve system with a feed system. For example, a contact lens rinse, a cleaning disinfector and preparations for storage and reusable use, are adapted for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

Example 9

In this example, eye wash preparations that do not contain antiseptics are adapted for storage and use with a one-way valve system with a delivery system. For example, preparations that are intended for washing eyes from surrounding pollutants are adapted for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

As an example, preparations that are intended for washing the eyes from surrounding pollutants, dust or specks are adapted for storage and use with a one-way valve system with a feed system, because they are prepared on a natural basis.

Despite the fact that the system was created for use with various natural preparations (without preservatives), this system can also be used with non-natural substances (with the addition of preservatives).

Claims (42)

1. Sealed on the entire surface of the one-way valve system with a fluid supply system, which includes
a source for storing a fluid substance in which an opening is made;
a valve system connected to the source opening, which includes
(i) an inner core that has an inlet for receiving fluid substance into the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core, and when pressure is applied to the fluid substance, the fluid substance passes through at least , one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance from the valve system, when pressure is applied to the fluid substance, and when pressure on the fluid substance is stopped, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core, before than the remainder of the tubular flexible membrane will return in tight contact with the outer surface of the inner core. 2. A one-way valve system sealed over the entire surface with a supply system according to claim 1, characterized in that the tubular flexible membrane has an axially elongated continuous collar at its one end, which is adjacent to the outlet in the casing, which completely covers the core. 3. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 1, characterized in that said membrane has an elongated flange radially outward at its second end, which borders the passage of the inner core, and the casing has an elongated radially outward flange that compresses said flange on the membrane is in fluid-tight contact with a radially outwardly extended flange at the passage opening into said inner core. 4. Sealed on the entire surface of the one-way valve system with a feed system according to claim 3, characterized in that the sleeve and connector on the source are configured to connect the valve system to the source. 5. Sealed on the entire surface of the one-way valve system with a feed system according to claim 4, characterized in that the connector is made in the form of a screw with a thread that engages with the sleeve. 6. Sealed on the entire surface of the one-way valve system with a supply system according to claim 4, characterized in that the sleeve and connector at the source protect the valve at the source and provide reliable locking fastening, which prevents the source from opening. 7. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 1, characterized in that the outlet in the casing is designed in such a way that it can deliver a given amount of fluid substance. 8. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that the outlet in the casing is formed of soft material. 9. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that the outlet in the casing is formed of a flexible material. 10. Sealed over the entire surface of a one-way valve system with a delivery system according to claim 1, characterized in that the casing is formed of an internal axially elongated flexible component surrounded by an axially elongated hard plastic shell. 11. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that it includes an external end for closing and creating a tightness with the specified valve system, sufficient to prevent external contamination from coming into contact with the valve system during storage. 12. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that at least two outlet exits pass from the passage through the inner core to the inner surface of the flexible membrane. 13. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that the source includes a reservoir capable of flattening, the volume of which decreases in proportion to the amount of fluid substance that is squeezed out of the reservoir. 14. Sealed on the entire surface of the one-way valve system with a delivery system according to item 13, wherein the said collapsible reservoir is selected from a bellows, a tube and an inner bag. 15. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that the axially elongated housing on the sides closes the source. 16. A one-way valve system sealed over the entire surface with a supply system according to claim 1, characterized in that the housing has a recess that extends axially to apply pressure to the starter to unload the collapsible reservoir. 17. A one-way valve system sealed over the entire surface with a supply system according to claim 1, characterized in that the casing has a closed outlet that opens slightly to supply fluid substance from the casing when pressure is applied to the source for discharge. 18. Sealed on the entire surface of the one-way valve system with a delivery system according to 17, characterized in that the outlet in the casing is impervious to fluid substance and does not allow fluid substance back into the outlet. 19. A one-way valve system with a supply system sealed over the entire surface of claim 1, characterized in that the inner core is connected to the pumping device and to the starter in such a way that the fluid substance leaves the outlet when the pressure on the starter decreases. 20. Sealed on the entire surface of the one-way valve system with a supply system according to claim 1, characterized in that the source is filled with a product that does not contain preservatives. 21. The one-way valve system sealed on the entire surface with the delivery system according to claim 20, characterized in that the products that do not contain preservatives include ophthalmology, otolaryngology, dermatology, gynecology products, as well as products intended for the treatment of anorectal, dermatological, pulmonary problems, and products that can be applied to the mucous membrane of the body. 22. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that the products that do not contain preservatives include products that are selected from one of the substances, such as methyl cellulose, hyaluronic acid, polyethylene glycol 400 0, 4%, propylene glycol 0.3%, glycerin and mineral oils. 23. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that the products that do not contain preservatives include products that are selected from one of the substances, such as timolol maleate 0.25% / 0, 50%, brimodenine ester 0.1%, bimatoprost 0.03% and grass simple 0.004%. 24. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that products that do not contain preservatives include products that are selected from one of the substances, such as olopatodine hydrochloride 0.1% and prednisolone ester one%. 25. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that products that do not contain preservatives include products that are selected from one of the substances, such as ketorolac 0.5% and diclofenac 0.1 % 26. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that the products that do not contain preservatives include products that are selected from one of the substances, such as phenylephrine 0.25% and pseudoephedrine 30 mg . 27. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that products that do not contain preservatives include products such as skin preparations; preparations for the scalp; corticosteroid creams, lotions and ointments; basic antibiotics and basic antifungal drugs. 28. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that products that do not contain preservatives include products such as skin preparations; preparations for the scalp; corticosteroid creams, lotions and ointments; basic antibiotics and basic antifungal drugs; therapeutic creams, including antibacterial, antiparasitic substances, creams for allergies and dermatitis, as well as moisturizers and dermatological compounds for dermatological problems. 29. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that products that do not contain preservatives include products such as creams, painkillers, helium lubricants and other drugs for the treatment of hemorrhoids. 30. A one-way valve system sealed over the entire surface with the delivery system according to claim 20, characterized in that products that do not contain preservatives include products that excrete adrenaline, an anticholinergic agent, corticosteroid hormone, and theopheline drugs. 31. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 20, characterized in that the products that do not contain preservatives include products that are selected from one of the substances, such as azoles, nystatin, butaconazole, butaconazole 2% , clotrimazole, clotrimazole 1%, metronidazole and trichomonas colpitis drug. 32. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 19, characterized in that the products may include preparations for the care of contact lenses. 33. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 19, characterized in that the products may include herbal products, cosmetic preparations, eye wash drops or skin care preparations. 34. Sealed on the entire surface of the one-way valve system with a delivery system according to claim 1, characterized in that the sealed on the entire surface of the one-way valve system with a delivery system can pass many doses of preservative-free preparation. 35. Sealed over the entire surface of a one-way valve system with a feed system for supplying a fluid substance without the addition of preservatives, which includes
a source for storing a fluid substance without the addition of preservatives in which an opening is made;
a valve system connected to the source opening, where said valve system includes
(i) an inner core that has an inlet for receiving fluid substance into the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core, and when pressure is applied to the fluid substance, the fluid substance passes without adding preservatives through at least one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance without adding preservatives from the valve system when pressure is applied to the fluid substance without adding preservatives, and
when the pressure on the fluid substance ceases, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core, before the remainder of the tubular flexible membrane returns to close contact with the outer surface of the inner core. 36. Sealed over the entire surface of a one-way valve system with a supply system for supplying a fluid substance without the addition of preservatives with multiple doses, which
a source for storing a fluid substance without the addition of preservatives, wherein said source has an opening;
a valve system connected to the source opening, which includes
(i) an inner core that has an inlet for receiving a fluid substance without adding preservatives to the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core and when pressure is applied to the fluid substance, the fluid substance passes without adding preservatives through at least one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance without adding preservatives from the valve system when pressure is applied to the fluid substance without adding preservatives, and
when the pressure on the fluid substance ceases, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core, before the remainder of the tubular flexible membrane returns to close contact with the outer surface of the inner core. 37. A feed system that includes
a source for storing a fluid substance that has an opening;
a valve system connected to the source opening, which includes
(i) an inner core that has an inlet for receiving fluid substance into the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core, and when pressure is applied to the fluid substance, the fluid substance passes through at least one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance from the valve system when pressure is applied to the fluid substance, and
when the pressure on the fluid substance ceases, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core before the remainder of the tubular flexible membrane returns to close contact with the outer surface of the inner core. 38. Sealed on the entire surface of the one-way valve system with a supply system, which includes
a source for storing a fluid substance that has an opening;
a valve system connected to the source opening, which includes
(i) an inner core that has an inlet for receiving fluid substance into the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core, and when pressure is applied to the fluid substance, the fluid substance passes through at least one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance from the valve system when pressure is applied to the fluid substance, and
when the pressure on the fluid substance ceases, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core before the remainder of the tubular flexible membrane returns to close contact with the outer surface of the inner core;
wherein at least one element from the inner shell, flexible membrane or casing contains an antibacterial substance. 39. A one-way valve system sealed over the entire surface with a delivery system according to claim 38, characterized in that the antimicrobial substance is selected either from silver ions contained within the ceramic carrier or from slowly released silver ion compounds. 40. Sealed over the entire surface of a one-way valve system with a supply system that includes
a source for storing a fluid substance that has an opening;
a valve system connected to the source opening, which includes
(i) an inner core that has an inlet for receiving fluid substance into the passage and at least one outlet from the passage,
(ii) a tubular flexible membrane that has a first end and a second end, the first end being thicker than the second end, the tubular flexible membrane being placed above the outer surface of the inner core, and when pressure is applied to the fluid substance, the fluid substance passes through at least one outlet and expands the specified membrane outward from the specified outer surface of the inner core;
a casing that closes the flexible membrane and has an outlet for supplying fluid substance from the valve system, when pressure is applied to the fluid substance, and when pressure on the fluid substance is stopped, the first end of the tubular flexible membrane returns to close contact with the outer surface of the inner core before, than the remainder of the tubular flexible membrane will return in tight contact with the outer surface of the inner core;
wherein at least one element from the inner shell, flexible membrane or casing contains a hydrostatic substance. 41. A one-way valve system with a delivery system according to claim 40, characterized in that the hydrostatic substance is selected from one of the substances: a positively charged substance, a low-viscosity substance or a substance with an elastic surface or with a waterproof coating. 42. A one-way valve system with a delivery system according to claim 41, characterized in that the low-viscosity material is a Teflon coating.

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