RU2147607C1 - Antibacterial toilet soap (variants) - Google Patents

Abstract

FIELD: fat and oil industry. SUBSTANCE: invention relates to production of cheap antibacterial toilet soap. Soap has saturated acid sodium salts of food fats or palm oil saturated acid sodium salts, or coconut saturated acid sodium salts, classic soap additions and triclozan. Ratio of components ensures to obtain good foaming soap exhibiting disinfecting and deodorizing effects. EFFECT: improved quality of soap. 2 cl, 4 tbl

Description

 The invention relates to the production of fat-based detergents, namely the production of antibacterial toilet soap designed to cleanse, deodorize and disinfect skin of the hands, face and body.

 Widely advertised is the Safeguard soap produced by Procter & Gamble. Soap that provides protection against bacteria, contains sodium salts of fatty acids (soap itself): sodium tallovat, sodium palmkernelate (sodium salt of fatty acids of palm kernel oil), sodium cocoate; as a neutralizing and overdosing additive - coconut acid; water, triclocarban (triclosan), aromatic additive, glycerin, sodium chloride, as complexone - tetrasodium salt of EDTA (ethylenediamine-tetraacetic acid); as a preservative antioxidant - BHT (butylhydroxytoluene), dyes.

 However, Safeguard soap swells quickly and is quickly consumed. Soap is uneconomical in use due to the low content of sodium salts of fatty acids - 70%.

 It is due to the selected optimal ratio of sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil and sodium salts of fatty acids of coconut oil 56-65 / 18-11% or 63-60 / 15-20% of the claimed soap has a higher hardness, less consumption rate, resistant to deformation, has an increased foaming and washing ability. The soap according to the invention is much cheaper compared to foreign samples.

 Any deviation from the found ratios of the components does not provide the above technical result.

Swelling as well as solubility of soap depends on the fatty acid composition. When soap interacts with water (at 18-23 ^o C), it first swells and then dissolves. In most cases, anhydrous soaps swell more slowly than 80%, and 73% much faster than 78%. When swelling, an increase in the volume of soap occurs, but in a smaller size than the volume of absorbed water. Soap swelling is accompanied by heat [1] and soap dissolution.

 The domestic industry does not produce antibacterial soap.

 The objective of the invention was the creation of high-quality, inexpensive antibacterial toilet soap, which effectively destroys harmful bacteria, disinfects cuts and scratches on the skin, has a deodorizing effect and foams well.

 The classic basis of toilet soap is sodium salts of aliphatic acids of coconut oil and beef fat, taken in the ratio of (15-25) / (75-85). The fatty acid composition of the soap is crucial in ensuring the required quality and physico-chemical parameters, the main of which are: hardness, uniformity, solubility, swelling, consumption rate, foaming and washing ability, level of skin irritation, color and aroma stability. An active search for equivalent, cheaper sources of raw materials continues, but the basis for high-quality toilet soaps is provided by this optimal combination of coconut and beef acids. Many recipes are known with the partial replacement of coconut aliphatic acids with bleached palm kernel and synthetic, and beef with acid of animal and vegetable salomas, palm, peanut and olive oils, lard, and different trends in composition prevail in different countries. Supplements of these fats usually do not exceed 10 - 20%.

 Increased attention to the cosmetic condition of the skin after washing determines a higher level of content in the modern toilet soap of dehydrating, softening and hydrating substances. Often supplements are administered in combination with glycerin. At the same time, rechargers perform a plasticizing function in concentrated soaps, which improves uniformity and facilitates mechanical processing.

 The rate of consumption, the consistency, as well as the technological properties of the soap largely depend on the moisture content, titer and iodine number of acids used. Maintaining high oleic fractions increases the ductility and solubility of soap, but contributes to its rapid rancidity. Therefore, antioxidants are added to soaps with a high content of unsaturated aliphatic acids. These are: polyatomic and spatially-hindered phenols, o-tolylbiguanidine, quercetin, lecithin, propolis, tocopherols, carotenoids and extracts containing them. Synergists of antioxidants are many complexones (in particular, EDTA and citric acid), amino acids, ascorbic acid, sorbic acid and their salts.

 When deviating from typical soap formulations, one often has to deal with changes in color and aroma, with cracking, deformation of the form with increased stickiness and soaking. Nevertheless, many soap manufacturers make such deviations, being guided mainly by economic considerations, compensating for the shortcomings by the introduction of stabilizers and fillers.

 As filler pigments, up to 1-2% of titanium dioxide or zinc oxide is introduced into the toilet soap. In addition, soap may include up to 4-6% glycerol [2].

 The difference of the claimed soap toilet antibacterial from soap Safeguard are presented in table. 1.

 A higher fat content of 74-80% is characterized by a qualitative number indicator (mass fraction of fatty acids in terms of the nominal mass of a piece of 100 g) g.

 Compared to Safeguard soap (with a quality number of 70) containing sodium salts of fatty acids: tall, palm kernel, coconut, the claimed antibacterial toilet soap (with a quality number of 74 - 80), contains sodium salts of edible fatty acids or palm sodium fatty acids and sodium salts of fatty acids of coconut oils. Mostly used cheap edible fats, so the cost of the claimed soap is much lower than Safeguard soap (2-3 times).

 Coconut acid is used in the Safeguard soap as an extinguishing agent, and the inventive toilet soap antibacterial uses cheaper vegetable oils (mostly sunflower oil), which also reduces the cost of domestic antibacterial soap.

 Liquid vegetable oils are composed mainly of unsaturated fatty acids: oleic and linoleic. Linoleic acid, like linolenic acid, is provitamin F and has moisturizing, regenerating and regenerating properties [3, 4].

Sunflower oil
Linoleic - 70%
Oleic - 16%
Palmitic - 7%
Stearin - 4%
Unsaponifiable fats (steroids: campesterol, β-sitosterol, stigmasterol) - 1%
Due to the high content of essential fatty acids, it has moisturizing, regenerating, regenerating properties.

Olive oil
Oleic - 3-81%
Linoleic - 5-15%
Palmitic - 7-14%
Stearin - 3-5%
Unsaponifiable fats (β-sitosterol, squalene) - 0.5-1%
The unsaponifiable fraction of olive oil is a famous emollient that is used to treat skin diseases. Olive oil itself has regenerating and moisturizing properties.

Cottonseed oil
Oleic - 29-44%
Linoleic - 33-50%
Palmitic, stearic - 29-33%
Fruit Seed Oil
Linoleic - 15-35%
Oleic - 55-75%
Palmitic - 5-8%
Unsaponifiable fats - 0.5%
It has moisturizing, regenerating, softening properties.

Soybean oil
Linoleic - 46.2-52.6%
Oleic - 21.9-26.6%
Palmitic - 9.5-12.5%
α-Linolenic - 7.9-8.5%
Stearin - 4.9-6.1%
Unsaponifiable fats (mainly β-sitosterol and tocopherols) - 0.5-1.6%
It has moisturizing and regenerating properties.

Coconut oil
Laurilova - 39-54%
Myristic - 15-23%
Caprylic - 5-10%
Oleic - 4-11%
Stearin - 1-4%
γ-Linolenic - 1-2%
It has emollient and moisturizing properties.

 The introduction of Antala P-2 allows us to ensure the operational properties of soap and reduce its cost.

 Instead of two components used in Safeguard soap: complexone - the tetrasodium salt of ethylenediamine-tetraacetic acid and the preservative-antioxidant - butylhydroxytoluene, the inventive soap uses Antal P-2, a multifunctional composition that simultaneously contains active ingredients: plasticizers, antioxidants, preservatives and complexones. Plasticizers affect the hardness and soakability of pieces of soap.

 As a pigment filler, titanium dioxide pigment is introduced into the toilet soap.

 The soap foams well, is resistant to deformation and has an increased foaming and washing ability. The presence of gloss, smoothness, as well as the "creaking" of hands after washing are inalienable qualities when using antibacterial toilet soap.

The essence of the invention (option N1) is that the claimed antibacterial toilet soap, consisting of sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil and sodium salts of fatty acids of coconut oil, sodium chloride, pigment, antioxidant complexone, glycerin, Triclosan, an over-spraying additive, perfume composition and water, is characterized in that it contains pigment titanium dioxide as a pigment, Antal P-2 as an antioxidant complexon, and Perv-2 as an antioxidant conductive agent - High oleic sunflower oil, refined, deodorized or refined olive or deodorized cottonseed salad, fruit or seeds and almonds, or soybean refined deodorized in the following ratio, wt.%:
Sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil - 56.00-65.00
Sodium salts of fatty acids of coconut oil - 18.00-11.00
Sodium chloride - 0.40-0.70
Pigment titanium dioxide - 0.10-0.30
Antal P-2 - 0.30-0.50
Glycerin - 2.00-2.50
Triclosan - 0.20-0.30
High oleic deodorized refined sunflower oil or olive oil, or deodorized cotton lettuce, or from fruit seeds and almonds, or deodorized soybean refined - 0.20-0.30
Perfume composition - 6.40-0.60
Drinking Water - Else
The essence of the invention (option N 2) is that the claimed antibacterial toilet soap, consisting of sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil and sodium salts of fatty acids of coconut oil, sodium chloride, pigment, antioxidant complexone, glycerin , a neutralizing agent, triclosan, an overwhelming additive, perfume composition and water, characterized in that it contains pigment titanium dioxide as a pigment, and Antal contains antioxidant complexon -2, citric acid as a neutralizing agent, deodorized refined sunflower oil or deodorized olive oil, or deodorized cotton lettuce, or from fruit seeds and almonds, or deodorized soybean, in the following ratio, wt. %:
Sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil - 63.00-60.00
Sodium salts of fatty acids of coconut oil - 15.00-20.00
Sodium chloride - 0.37-0.40
Pigment titanium dioxide - 0.10-0.30
Antal P-2 - 0.30-0.50
Glycerin - 2.00-2.50
Citric acid - 0.30-0.40
Triclosan - 0.30 - 0.50
High oleic deodorized sunflower oil, refined or olive oil, or deodorized cotton lettuce, or from fruit seeds and almonds, or deodorized soybean refined - 0.30 - 0.50
Perfume composition - 1.30-1.50
Drinking Water - Else
Triclosan - C ₁₂ H ₁₇ Cl ₃ O ₂
2,4,4'-trichloro-2'-hydroxy-diphenyl ether
Powder with a pleasant faint odor. It has a wide range of antimicrobial effects on gram-positive and gram-negative bacteria, and is also effective against mold (or microscopic fungi) and yeast.

 Triclosan acts on bacteria that cause unpleasant body odors (for example, representatives of Micrococcus and Corynebacteria) on pathogenic and pathogenic bacteria (for example, Enterobacteriaeceae class, including pathogenic Echeriebia coli type 0157: H7, Staphylococcus, Streptococcus microflora, and representatives of the yeast Candida) and antibiotic-resistant bacteria (e.g., methicillin-resistant Staphylococcus and vancumucin-resistant bacteria). Triclosan has high remanent effectiveness when applied to the skin, is stable to hydrolysis [5, 6, 7, 8]. Passed rigorous tests for toxicity and environmental friendliness. It is recommended for use mainly for deodorant soap. Water soluble.

 Triclosan is stable with respect to all ingredients commonly found in soaps. Soap containing triclosan can be stored for several years at room temperature without losing its active antimicrobial effect.

 The compositions of toilet soap for several examples are given in table. 2 and 3.

 Antibacterial toilet soap (Option 1 Example 1) with a content of sodium salts of fatty acids - 70% quickly swells and is quickly consumed.

 Reducing the input of Antal P-2 to 0.2% (Option 1 - Example 3 and Option 2 - Example 3) reduces the plasticizing properties and can cause rancidity of soap.

 A decrease in the administration of triclosan to 0.10% (Option 1 - Example 1) does not provide a given antibacterial effect.

 Thus, studies have shown that going beyond the stated amounts of ingredients in the direction of increasing leads to a rise in price of soap, and in the direction of decreasing, causes a deterioration in the operational properties of soap, or does not provide a given antibacterial effect.

 Antibacterial toilet soap option 2 is prepared as follows: the base of soap is prepared from neutral fats in an indirect way step by step [9]: the first saponification of fats with sodium hydroxide solution, the first salting out of soap glue with sodium chloride solution, the second saponification, the second salting out with sodium hydroxide solution, washing and the third salting out, grinding, settling and draining the base into the converter. Here, the neutralization of the soap base with citric acid is carried out. Thanks to neutralization, free alkali and soda products are removed, the soap becomes softer, gently and gently cleanses the skin.

 After drying and preliminary mechanical treatment, additives are introduced into the toilet base: antioxidant, triclosan (previously dissolved in vegetable oil), pigment titanium dioxide, perfume composition. Then the soap mass is subjected to additional mechanical processing (sawing), followed by molding, cutting the obtained pieces, stamping soap, wrapping in labels and packaging.

 Option 1. The technology for preparing toilet antibacterial soap differs from option 2 in the absence of a neutralization stage.

 As a result of the above technological operations of step-by-step saponification, salting out, grinding and settling in a soap base, up to 2.00 - 2.50% glycerol remains, which helps to retain moisture in the skin after washing.

 The finished antibacterial toilet soap has an aroma of fantasy direction with floral and citrus notes.

 An experimental batch of antibacterial toilet soap has been developed.

 The finished soap meets the requirements of GOST 28546-90.

 Physico-chemical properties of the claimed soap antibacterial toilet according to examples are given in table. 4.

 Tests were conducted at the Center for Cosmetic Correction of the Central Clinical Hospital of the Medical Association of the Russian Academy of Sciences (Central Clinical Hospital of the Russian Academy of Sciences). According to the results of experimental clinical trials of toilet soap antibacterial, a conclusion is obtained.

 Experimental studies were carried out on white rats, females, weighing 210-220 g. The results of the studies showed that with prolonged skin application (14 applications) of toilet soap, it does not have a general toxic, irritating and allergenic effect on the skin of animals: skin condition, coat, appetite, behavioral reactions, weight gain in experimental animals did not differ from the control.

 The degree of microbial contamination and the antimicrobial effect of toilet antibacterial soap were evaluated by laboratory tests. The following indicators were determined: total number of microorganisms in 1 g; the presence of bacteria of the families: Enterobacteriacea, Ps.aeruginosa, St.aureus; mold fungi, Candida fungi.

 Conclusion: toilet soap antibacterial meets the requirements of microbial purity. It has a pronounced antimicrobial effect against E. coli, St.aureus, Ps.aeruginosa, B. subtilis.

 In terms of the content of salts of heavy metals and pH, the soap meets the norms and requirements of regulatory documentation.

 Clinical trials were conducted on 25 probants for 2 weeks. Prior to the start of clinical testing, patchwork was made on the skin of the forearm to assess the local irritating effect, in no case were signs of irritation observed.

 Evaluation of toilet antibacterial soap was carried out subjectively with an emphasis on the presence of irritating and allergenic effects during clinical examination.

 The results of clinical testing did not reveal pathological reactions of the patient’s body to the soap being studied. Throughout the test period, there were no signs of irritating and allergenic effects.

List of references
1. Handbook of soap production, ed. THEM. Tovbin. M .: Food industry, 1974, 186-187 p.

 2. M. Yu. Pletnev. Cosmetic and hygienic detergents, M .: Chemistry, 1990, 233-245 p.

 3. B.N. Tyutyunnikov, Chemistry of fats, M., Food industry, 1968, 10 pp.

 4. The lipid barrier of the skin and cosmetics: Sat./Art. A.A. Margolina, E.I. Hernandez - M., 1998, 150-158 s. - (Ser. "Theoretical cosmetology").

 5. G. Schlegel. General microbiology. M .: Mir, 1987, 563 p.

 6. Z.A. Arkadyev, A.M. Bezborodov, I.N. Blokhin et al. Industrial Microbiology, ed. Egorova N.S. M .: Higher school, 1989, 687 p.

 7. A. R. Cox Efficacy of the antimicrobial agent triclosan in topical deodorant products: recent developments in vivo. J. Soc. Cosmet. Chem., 1987, 38, 223-231.

 8. J. Regos, H.R. Hitz Antimicrobial spectrum of triclosan, a broad spectrum antimicrobial agent for topical application, Zbl.Bakt. Hyd., 1. Abt. Orig., 1974, A226, 376-389.

 9. N.S. Harutyunyan et al. Fats Processing Technology, Moscow: Pishchepromizdat, 1998, p. 394, 401-402.

Claims (1)

1. Antibacterial toilet soap, consisting of sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil and sodium salts of fatty acids of coconut oil, sodium chloride, pigment, antioxidant complexone, glycerin, triclosan, an extinguishing additive, perfume composition and water, characterized in that it contains pigment titanium dioxide as a pigment, Antal P-2 as antioxidant complexon, and high-oleic sunflower oil deodor deodorizing agent anced refined or refined olive or deodorized cottonseed salad, fruit or seeds and almonds, or soybean refined deodorized, with the following component ratio, wt.%:
Fatty acid sodium salts of edible fats or palm oil fatty acids - 56.00 - 65.00
Coconut oil fatty acid sodium salts - 18.00 - 11.00
Sodium chloride - 0.40 - 0.70
Pigment titanium dioxide - 0.10 - 0.30
Antal P-2 - 0.30 - 0.50
Glycerin - 2.00 - 2.50
Triclosan - 0.20 - 0.30
High oleic deodorized sunflower oil, refined or olive oil, or deodorized cotton lettuce, or from fruit seeds and almonds, or deodorized soybean refined - 0.20 - 0.30
Perfume composition - 0.40 - 0.60
Drinking Water - Else
2. Antibacterial toilet soap, consisting of sodium salts of fatty acids of edible fats, sodium salts of fatty acids of palm oil and sodium salts of fatty acids of coconut oil, sodium chloride, pigment, antioxidant complex, glycerin, a neutralizing agent, triclosan, an extinguishing agent, perfume composition and water, characterized in that it contains pigment titanium dioxide as a pigment, Antal P-2 as antioxidant complexon, and citric acid as a neutralizing agent, in quality TBE superfatting additives - High oleic sunflower oil, refined, deodorized or refined olive or deodorized cottonseed salad, fruit or seeds and almonds, or soybean refined deodorized, with the following component ratio, wt.%:
Sodium salts of fatty acids of edible fats or sodium salts of fatty acids of palm oil - 63.00 - 60.00
Coconut oil fatty acid sodium salts - 15.00 - 20.00
Sodium chloride - 0.37 - 0.40
Pigment titanium dioxide - 0.10 - 0.30
Antal P-2 - 0.30 - 0.50
Glycerin - 2.00 - 2.50
Citric acid - 0.30 - 0.40
Triclosan - 0.30 - 0.50
High oleic deodorized sunflower oil, refined or olive oil, or deodorized cotton lettuce, or from fruit seeds and almonds, or deodorized soybean refined - 0.30 - 0.50
Perfume composition - 1.30 - 1.50
Drinking Water - Else

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