RS58188B2 - Postupci za tretiranje osteogeneze imperfekta - Google Patents

Postupci za tretiranje osteogeneze imperfekta

Info

Publication number: RS58188B2
Authority: RS; Serbia
Prior art keywords: methods; osteogenesis imperfecta; treating osteogenesis; treating; imperfecta
Prior art date: 2013-03-20

Application number

RS20181438A

Other languages

English (en)

Inventor

Brendan Lee

Kuber T Sampath

Original Assignee

Genzyme Corp

Baylor College Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-20

Filing date

2014-03-20

Publication date

2022-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50483613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS58188(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-03-20 Application filed by Genzyme Corp, Baylor College Medicine filed Critical Genzyme Corp

2019-03-29 Publication of RS58188B1 publication Critical patent/RS58188B1/sr

2022-06-30 Publication of RS58188B2 publication Critical patent/RS58188B2/sr

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Mycology (AREA)
Microbiology (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Inorganic Chemistry (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)

RS20181438A 2013-03-20 2014-03-20 Postupci za tretiranje osteogeneze imperfekta RS58188B2 (sr)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201361803647P	2013-03-20	2013-03-20
US201361875399P	2013-09-09	2013-09-09
US201361883151P	2013-09-26	2013-09-26
EP14717386.8A EP2976359B2 (en)	2013-03-20	2014-03-20	Methods for treating osteogenesis imperfecta
PCT/US2014/031279 WO2014153435A1 (en)	2013-03-20	2014-03-20	Methods for treating osteogenesis imperfecta

Publications (2)

Publication Number	Publication Date
RS58188B1 RS58188B1 (sr)	2019-03-29
RS58188B2 true RS58188B2 (sr)	2022-06-30

Family

ID=50483613

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
RS20191624A RS59673B1 (sr)	2013-03-20	2014-03-20	Postupci za tretiranje osteogeneze imperfekta
RS20181438A RS58188B2 (sr)	2013-03-20	2014-03-20	Postupci za tretiranje osteogeneze imperfekta

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
RS20191624A RS59673B1 (sr)	2013-03-20	2014-03-20	Postupci za tretiranje osteogeneze imperfekta

Country Status (27)

Country	Link
US (4)	US9598486B2 (sr)
EP (3)	EP3312195B1 (sr)
JP (3)	JP6483086B2 (sr)
KR (1)	KR102257138B1 (sr)
CN (2)	CN111000997A (sr)
AU (1)	AU2014235933B2 (sr)
CA (1)	CA2907422C (sr)
CL (1)	CL2015002801A1 (sr)
DK (2)	DK2976359T4 (sr)
EA (1)	EA032327B1 (sr)
ES (2)	ES2700238T5 (sr)
HK (2)	HK1213576A1 (sr)
HR (2)	HRP20181939T4 (sr)
HU (1)	HUE046702T2 (sr)
IL (2)	IL241461B (sr)
LT (2)	LT3312195T (sr)
MX (2)	MX369360B (sr)
MY (1)	MY172324A (sr)
PH (2)	PH12015501864B1 (sr)
PL (2)	PL2976359T5 (sr)
PT (2)	PT3312195T (sr)
RS (2)	RS59673B1 (sr)
SG (2)	SG10201701985YA (sr)
SI (2)	SI2976359T2 (sr)
TW (1)	TWI629995B (sr)
UY (1)	UY35493A (sr)
WO (1)	WO2014153435A1 (sr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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RS59673B1 (sr) *	2013-03-20	2020-01-31	Genzyme Corp	Postupci za tretiranje osteogeneze imperfekta
CA3033614A1 (en) *	2016-08-11	2018-02-15	Precithera, Inc.	Tgf-.beta. antagonist conjugates
CN106755395B (zh) *	2016-12-16	2020-05-12	山东第一医科大学(山东省医学科学院)	Xi型成骨不全致病基因fkbp10的突变位点及其应用
TWI832600B (zh) *	2017-01-20	2024-02-11	美商健臻公司	骨靶向抗體
EP3571227A1 (en) *	2017-01-20	2019-11-27	Sanofi	Anti-tgf-beta antibodies and their use
TWI787230B (zh)	2017-01-20	2022-12-21	法商賽諾菲公司	抗ＴＧＦ-β抗體及其用途
AR110904A1 (es) *	2017-01-20	2019-05-15	Sanofi Sa	ANTICUERPOS ANTI-TGF-b Y SU USO
WO2019113123A1 (en) *	2017-12-04	2019-06-13	Precithera, Inc.	TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING
AU2019301283B2 (en)	2018-07-10	2024-12-19	Sanofi	Combination therapies against cancer targeting CD38 and TGF-beta
MX2023004725A (es) *	2020-10-23	2024-02-23	Hq Han	Antagonistas bifuncionales del factor de necrosis tumoral alfa y del factor de crecimiento transformante beta y usos de los mismos.
MX2023013184A (es) *	2021-05-07	2023-12-05	Baylor College Medicine	Tratamiento de la osteogenesis imperfecta de moderada a grave.
CN113501879B (zh) *	2021-06-30	2022-09-06	拜盖特生物科技(上海)有限公司	一种解除肿瘤免疫微环境中免疫抑制的双功能抗体及其应用和制备方法
IL312489A (en) *	2021-11-01	2024-07-01	Genzyme Corp	Treatment of defective bone formation
WO2024149381A1 (en) *	2023-01-13	2024-07-18	Shanghai Kaijin Biotechnology, Ltd	Multi-specific polypeptide complexes

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US7368111B2 (en) *	1995-10-06	2008-05-06	Cambridge Antibody Technology Limited	Human antibodies specific for TGFβ2
DE19742706B4 (de)	1997-09-26	2013-07-25	Pieris Proteolab Ag	Lipocalinmuteine
AU1525700A (en) *	1998-11-19	2000-06-05	Board Of Trustees Of The University Of Arkansas, The	Increasing bone strength with selected bisphosphonates
US20040009535A1 (en)	1998-11-27	2004-01-15	Celltech R&D, Inc.	Compositions and methods for increasing bone mineralization
EP1721979B1 (en) *	1998-11-27	2010-09-15	Ucb, S.A.	Compositions and methods for increasing bone mineralisation
US6492497B1 (en) *	1999-04-30	2002-12-10	Cambridge Antibody Technology Limited	Specific binding members for TGFbeta1
CA2308532C (en) *	1999-05-12	2005-11-29	Gador S.A.	Use of bisphosphonates for the treatment of osteogenesis imperfecta
US6629949B1 (en)	2000-05-08	2003-10-07	Sterling Medivations, Inc.	Micro infusion drug delivery device
US6659982B2 (en)	2000-05-08	2003-12-09	Sterling Medivations, Inc.	Micro infusion drug delivery device
AU2006213875B2 (en)	2005-02-08	2010-08-19	Genzyme Corporation	Antibodies to TGFBETA
TW200714289A (en) *	2005-02-28	2007-04-16	Genentech Inc	Treatment of bone disorders
US7592429B2 (en) *	2005-05-03	2009-09-22	Ucb Sa	Sclerostin-binding antibody
ATE545657T1 (de) *	2005-12-23	2012-03-15	Lilly Co Eli	Tgf-beta antikörper
WO2008022182A1 (en) *	2006-08-16	2008-02-21	The Uab Research Foundation	Methods for promoting coupling between bone formation and resorption
KR20190026047A (ko) *	2007-02-09	2019-03-12	악셀레론 파마 인코포레이티드	액티빈-ＡｃｔＲⅡＡ 길항제 및 암 환자에서 골 생장을 촉진시키기 위한 이의 용도
CA2683816A1 (en) *	2007-04-26	2008-11-06	President And Fellows Of Harvard College	Assays for the identification of compounds that modulate bone formation and mineralization
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ES2598006T3 (es) *	2009-04-24	2017-01-24	Vanderbilt University	Anticuerpos anti-TGF-beta para la inducción del crecimiento óseo
RS59673B1 (sr) *	2013-03-20	2020-01-31	Genzyme Corp	Postupci za tretiranje osteogeneze imperfekta

2014
- 2014-03-20 RS RS20191624A patent/RS59673B1/sr unknown
- 2014-03-20 EP EP17206987.4A patent/EP3312195B1/en active Active
- 2014-03-20 CA CA2907422A patent/CA2907422C/en active Active
- 2014-03-20 EA EA201591843A patent/EA032327B1/ru not_active IP Right Cessation
- 2014-03-20 SG SG10201701985YA patent/SG10201701985YA/en unknown
- 2014-03-20 MX MX2015013402A patent/MX369360B/es active IP Right Grant
- 2014-03-20 PT PT172069874T patent/PT3312195T/pt unknown
- 2014-03-20 MY MYPI2015702733A patent/MY172324A/en unknown
- 2014-03-20 CN CN201910988588.9A patent/CN111000997A/zh active Pending
- 2014-03-20 PL PL14717386.8T patent/PL2976359T5/pl unknown
- 2014-03-20 EP EP14717386.8A patent/EP2976359B2/en active Active
- 2014-03-20 HR HRP20181939TT patent/HRP20181939T4/hr unknown
- 2014-03-20 TW TW103110468A patent/TWI629995B/zh active
- 2014-03-20 DK DK14717386.8T patent/DK2976359T4/da active
- 2014-03-20 PL PL17206987T patent/PL3312195T3/pl unknown
- 2014-03-20 SI SI201430985T patent/SI2976359T2/sl unknown
- 2014-03-20 SG SG11201506683XA patent/SG11201506683XA/en unknown
- 2014-03-20 ES ES14717386T patent/ES2700238T5/es active Active
- 2014-03-20 SI SI201431435T patent/SI3312195T1/sl unknown
- 2014-03-20 KR KR1020157028130A patent/KR102257138B1/ko active IP Right Grant
- 2014-03-20 ES ES17206987T patent/ES2763869T3/es active Active
- 2014-03-20 DK DK17206987.4T patent/DK3312195T3/da active
- 2014-03-20 CN CN201480028990.8A patent/CN105229028B/zh active Active
- 2014-03-20 LT LTEP17206987.4T patent/LT3312195T/lt unknown
- 2014-03-20 AU AU2014235933A patent/AU2014235933B2/en active Active
- 2014-03-20 JP JP2016504355A patent/JP6483086B2/ja active Active
- 2014-03-20 EP EP19194235.8A patent/EP3640260A1/en active Pending
- 2014-03-20 PT PT14717386T patent/PT2976359T/pt unknown
- 2014-03-20 HU HUE17206987A patent/HUE046702T2/hu unknown
- 2014-03-20 WO PCT/US2014/031279 patent/WO2014153435A1/en active Application Filing
- 2014-03-20 RS RS20181438A patent/RS58188B2/sr unknown
- 2014-03-20 LT LTEP14717386.8T patent/LT2976359T/lt unknown
- 2014-03-20 UY UY0001035493A patent/UY35493A/es not_active Application Discontinuation
- 2014-03-20 US US14/772,708 patent/US9598486B2/en active Active
2015
- 2015-08-25 PH PH12015501864A patent/PH12015501864B1/en unknown
- 2015-09-10 IL IL241461A patent/IL241461B/en unknown
- 2015-09-17 CL CL2015002801A patent/CL2015002801A1/es unknown
- 2015-09-18 MX MX2019009122A patent/MX2019009122A/es unknown
2016
- 2016-02-11 HK HK16101478.1A patent/HK1213576A1/zh unknown
- 2016-02-11 HK HK18112865.7A patent/HK1253717A1/zh unknown
2017
- 2017-02-08 US US15/427,920 patent/US10377819B2/en active Active
2019
- 2019-02-06 PH PH12019500261A patent/PH12019500261A1/en unknown
- 2019-02-12 JP JP2019022397A patent/JP6677837B2/ja active Active
- 2019-07-01 US US16/459,023 patent/US11230595B2/en active Active
- 2019-12-17 HR HRP20192277TT patent/HRP20192277T1/hr unknown
2020
- 2020-03-12 JP JP2020042524A patent/JP7016113B2/ja active Active
2021
- 2021-11-08 IL IL287915A patent/IL287915A/en unknown
- 2021-12-09 US US17/547,069 patent/US20220195025A1/en active Pending

Also Published As

Publication number	Publication date
ES2700238T3 (es)	2019-02-14
HRP20181939T4 (hr)	2022-05-13
RS58188B1 (sr)	2019-03-29
IL241461B (en)	2021-12-01
IL287915A (en)	2022-01-01
EA201591843A1 (ru)	2016-01-29
EP3312195A1 (en)	2018-04-25
HRP20192277T1 (hr)	2020-03-06
WO2014153435A1 (en)	2014-09-25
CA2907422C (en)	2021-08-31
CL2015002801A1 (es)	2016-08-12
NZ712353A (en)	2021-04-30
KR102257138B1 (ko)	2021-05-26
SG10201701985YA (en)	2017-04-27
US20220195025A1 (en)	2022-06-23
HUE046702T2 (hu)	2020-03-30
US9598486B2 (en)	2017-03-21
SI2976359T2 (sl)	2022-05-31
BR112015023905A2 (pt)	2017-10-24
AU2014235933B2 (en)	2019-01-24
PL2976359T3 (pl)	2019-03-29
AU2014235933A1 (en)	2015-10-01
PH12019500261B1 (en)	2020-07-20
MX2019009122A (es)	2019-09-16
ES2700238T5 (es)	2022-05-20
PT2976359T (pt)	2018-12-05
LT2976359T (lt)	2018-12-27
EP2976359A1 (en)	2016-01-27
MY172324A (en)	2019-11-21
LT3312195T (lt)	2020-01-10
SI2976359T1 (sl)	2019-03-29
JP6483086B2 (ja)	2019-03-13
EP2976359B2 (en)	2022-03-23
PH12019500261A1 (en)	2020-07-20
HK1253717A1 (zh)	2019-06-28
JP7016113B2 (ja)	2022-02-04
MX369360B (es)	2019-11-06
SG11201506683XA (en)	2015-09-29
DK2976359T3 (da)	2019-01-02
KR20150132262A (ko)	2015-11-25
US20160031979A1 (en)	2016-02-04
JP6677837B2 (ja)	2020-04-08
CN105229028B (zh)	2019-11-08
RS59673B1 (sr)	2020-01-31
US20190389943A1 (en)	2019-12-26
US10377819B2 (en)	2019-08-13
US11230595B2 (en)	2022-01-25
PH12015501864A1 (en)	2015-12-07
TW201524515A (zh)	2015-07-01
PH12015501864B1 (en)	2015-12-07
HK1213576A1 (zh)	2016-07-08
HRP20181939T1 (hr)	2019-01-25
CN111000997A (zh)	2020-04-14
EP3312195B1 (en)	2019-10-09
PL3312195T3 (pl)	2020-04-30
PL2976359T5 (pl)	2022-07-18
SI3312195T1 (sl)	2020-02-28
JP2016519093A (ja)	2016-06-30
EA032327B1 (ru)	2019-05-31
CA2907422A1 (en)	2014-09-25
US20170247439A1 (en)	2017-08-31
MX2015013402A (es)	2016-01-08
ES2763869T3 (es)	2020-06-01
UY35493A (es)	2014-11-28
JP2020109110A (ja)	2020-07-16
EP2976359B1 (en)	2018-08-29
IL241461A0 (en)	2015-11-30
DK2976359T4 (da)	2022-06-13
CN105229028A (zh)	2016-01-06
DK3312195T3 (da)	2020-01-06
EP3640260A1 (en)	2020-04-22
TWI629995B (zh)	2018-07-21
PT3312195T (pt)	2019-12-23
JP2019089826A (ja)	2019-06-13

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