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RS51146B - Novi difenil-azetidinon sa poboljšanim fiziološkim osobinama postupak za njegovu proizvodnju,lekovi koji sadrže ovo jedinjenje i njihova upotreba - Google Patents

Novi difenil-azetidinon sa poboljšanim fiziološkim osobinama postupak za njegovu proizvodnju,lekovi koji sadrže ovo jedinjenje i njihova upotreba

Info

Publication number
RS51146B
RS51146B YUP-2005/0719A YUP20050719A RS51146B RS 51146 B RS51146 B RS 51146B YU P20050719 A YUP20050719 A YU P20050719A RS 51146 B RS51146 B RS 51146B
Authority
RS
Serbia
Prior art keywords
compound
phzsiological
improved
production method
corresponding production
Prior art date
Application number
YUP-2005/0719A
Other languages
English (en)
Inventor
Andreas Lindenschmidt
Gerhard Jaehne
Wendelin Frick
Heiner Glombik
Werner Kramer
Hubert Heuer
Stefanie Flohr
Hans-Ludwig Schaefer
Eric Galia
Original Assignee
Sanofi-Aventis Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh. filed Critical Sanofi-Aventis Deutschland Gmbh.
Publication of RS20050719A publication Critical patent/RS20050719A/sr
Publication of RS51146B publication Critical patent/RS51146B/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Jedinjenje formule I,kao i njegove farmaceutski prihvatljive soli.Prijava sadrži još 13 patentnih zahteva.
YUP-2005/0719A 2003-04-01 2004-03-16 Novi difenil-azetidinon sa poboljšanim fiziološkim osobinama postupak za njegovu proizvodnju,lekovi koji sadrže ovo jedinjenje i njihova upotreba RS51146B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
PCT/EP2004/002690 WO2004087655A1 (de) 2003-04-01 2004-03-16 Neues diphenylazetidinon mit verbesserten physiologischen eigenschaften, verfahren zu dessen herstellung, diese verbindungen enthaltende arzneimittel und dessen verwendung

Publications (2)

Publication Number Publication Date
RS20050719A RS20050719A (en) 2008-04-04
RS51146B true RS51146B (sr) 2010-10-31

Family

ID=33103147

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0719A RS51146B (sr) 2003-04-01 2004-03-16 Novi difenil-azetidinon sa poboljšanim fiziološkim osobinama postupak za njegovu proizvodnju,lekovi koji sadrže ovo jedinjenje i njihova upotreba

Country Status (44)

Country Link
US (2) US7205290B2 (sr)
EP (2) EP1862455B1 (sr)
JP (1) JP2006522040A (sr)
KR (1) KR20050119180A (sr)
CN (2) CN100361970C (sr)
AR (1) AR043783A1 (sr)
AT (2) ATE423766T1 (sr)
AU (1) AU2004226287B2 (sr)
BR (1) BRPI0408920A (sr)
CA (1) CA2520689A1 (sr)
CL (1) CL43489B (sr)
CR (1) CR7995A (sr)
CY (2) CY1107398T1 (sr)
DE (3) DE10314610A1 (sr)
DK (2) DK1613589T3 (sr)
EC (1) ECSP056071A (sr)
ES (2) ES2322876T3 (sr)
GT (1) GT200400058A (sr)
HK (1) HK1087697A1 (sr)
HN (1) HN2004000109A (sr)
HR (1) HRP20050870A2 (sr)
JO (1) JO2493B1 (sr)
MA (1) MA27753A1 (sr)
ME (1) MEP41408A (sr)
MX (1) MXPA05010128A (sr)
MY (1) MY136269A (sr)
NI (1) NI200500164A (sr)
NO (1) NO20055001L (sr)
NZ (1) NZ542751A (sr)
PA (1) PA8599401A1 (sr)
PE (1) PE20050011A1 (sr)
PL (2) PL1862455T3 (sr)
PT (2) PT1613589E (sr)
RS (1) RS51146B (sr)
RU (1) RU2334737C2 (sr)
SA (1) SA04250154B1 (sr)
SI (2) SI1862455T1 (sr)
SV (1) SV2004001756A (sr)
TN (1) TNSN05244A1 (sr)
TW (1) TW200504009A (sr)
UA (1) UA80754C2 (sr)
UY (1) UY28253A1 (sr)
WO (1) WO2004087655A1 (sr)
ZA (1) ZA200506708B (sr)

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DE102007029612A1 (de) * 2007-06-27 2009-01-08 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester
US20080319218A1 (en) * 2007-06-22 2008-12-25 Andreas Haubrich Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
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DE102008059772A1 (de) 2008-12-01 2010-06-02 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung eines Diphenylazetidinons
WO2009112203A1 (de) * 2008-03-14 2009-09-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur herstellung eines diphenylazetidinons
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
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Also Published As

Publication number Publication date
CR7995A (es) 2006-09-22
CL43489B (es) 2005-01-21
ES2298731T3 (es) 2008-05-16
US7205290B2 (en) 2007-04-17
DK1862455T3 (da) 2009-06-02
TW200504009A (en) 2005-02-01
SI1862455T1 (sl) 2009-06-30
EP1862455A3 (de) 2007-12-12
JP2006522040A (ja) 2006-09-28
EP1862455A2 (de) 2007-12-05
PL1613589T3 (pl) 2008-07-31
EP1613589A1 (de) 2006-01-11
JO2493B1 (en) 2009-10-05
ATE423766T1 (de) 2009-03-15
RU2005133631A (ru) 2006-03-10
NO20055001L (no) 2005-10-27
AU2004226287B2 (en) 2010-03-18
CN100361970C (zh) 2008-01-16
AU2004226287A1 (en) 2004-10-14
CA2520689A1 (en) 2004-10-14
PE20050011A1 (es) 2005-02-28
DE502004006195D1 (de) 2008-03-27
MY136269A (en) 2008-09-30
ATE386020T1 (de) 2008-03-15
DE502004009059D1 (de) 2009-04-09
HN2004000109A (es) 2008-02-21
KR20050119180A (ko) 2005-12-20
WO2004087655A1 (de) 2004-10-14
PT1862455E (pt) 2009-04-23
PT1613589E (pt) 2008-03-27
ECSP056071A (es) 2006-01-27
SV2004001756A (es) 2004-11-18
EP1613589B1 (de) 2008-02-13
MEP41408A (en) 2011-02-10
NI200500164A (es) 2006-01-11
RS20050719A (en) 2008-04-04
DK1613589T3 (da) 2008-06-09
MA27753A1 (fr) 2006-02-01
RU2334737C2 (ru) 2008-09-27
DE10314610A1 (de) 2004-11-04
SA04250154B1 (ar) 2007-10-29
HRP20050870A2 (en) 2006-10-31
HK1087697A1 (en) 2006-10-20
ES2322876T3 (es) 2009-06-30
CN101139306A (zh) 2008-03-12
UA80754C2 (en) 2007-10-25
CN1768034A (zh) 2006-05-03
PA8599401A1 (es) 2004-10-08
NZ542751A (en) 2007-05-31
UY28253A1 (es) 2004-11-08
CY1109055T1 (el) 2014-07-02
AR043783A1 (es) 2005-08-10
PL1862455T3 (pl) 2009-07-31
GT200400058A (es) 2004-11-10
EP1862455B1 (de) 2009-02-25
SI1613589T1 (sl) 2008-06-30
CY1107398T1 (el) 2012-12-19
US20070197498A1 (en) 2007-08-23
US20050020563A1 (en) 2005-01-27
BRPI0408920A (pt) 2006-03-28
US7772429B2 (en) 2010-08-10
TNSN05244A1 (en) 2007-06-11
MXPA05010128A (es) 2005-11-16
ZA200506708B (en) 2007-01-31

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