Nothing Special   »   [go: up one dir, main page]

PT87105A - Process for preparing a synthetic resin based on a polystyrene - Google Patents

Process for preparing a synthetic resin based on a polystyrene

Info

Publication number
PT87105A
PT87105A PT87105A PT8710588A PT87105A PT 87105 A PT87105 A PT 87105A PT 87105 A PT87105 A PT 87105A PT 8710588 A PT8710588 A PT 8710588A PT 87105 A PT87105 A PT 87105A
Authority
PT
Portugal
Prior art keywords
polystyrene
synthetic resin
resin based
solid phase
support
Prior art date
Application number
PT87105A
Other languages
English (en)
Other versions
PT87105B (pt
Inventor
Hans Rink
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT87105A publication Critical patent/PT87105A/pt
Publication of PT87105B publication Critical patent/PT87105B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/50—Partial depolymerisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glass Compositions (AREA)
  • Polyamides (AREA)
  • Working-Up Tar And Pitch (AREA)
  • Paper (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)
PT87105A 1987-03-30 1988-03-28 Processo para a preparacao de uma resina sintetica a base de um poli-estireno PT87105B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH121487 1987-03-30

Publications (2)

Publication Number Publication Date
PT87105A true PT87105A (pt) 1988-04-01
PT87105B PT87105B (pt) 1992-07-31

Family

ID=4205167

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87105A PT87105B (pt) 1987-03-30 1988-03-28 Processo para a preparacao de uma resina sintetica a base de um poli-estireno

Country Status (19)

Country Link
US (3) US4859736A (pt)
EP (1) EP0285562B1 (pt)
JP (1) JP2513775B2 (pt)
KR (1) KR950013679B1 (pt)
AT (1) ATE88726T1 (pt)
AU (1) AU615181B2 (pt)
CA (1) CA1318462C (pt)
DD (3) DD284031A5 (pt)
DE (1) DE3880541D1 (pt)
DK (1) DK175042B1 (pt)
ES (1) ES2054863T3 (pt)
FI (1) FI90780C (pt)
GR (1) GR3007996T3 (pt)
HU (1) HU208155B (pt)
IE (1) IE61485B1 (pt)
IL (1) IL85884A (pt)
MX (1) MX10917A (pt)
PT (1) PT87105B (pt)
YU (1) YU62588A (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5212288A (en) * 1990-02-20 1993-05-18 Syntex (U.S.A.) Inc. Temporary minimal protection synthesis of serine-containing polypeptides
US5155166A (en) * 1990-06-18 1992-10-13 Eastman Kodak Company Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to carboxylated particles and a kit containing same
US5071565A (en) * 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
US5550215A (en) * 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
IE921942A1 (en) * 1992-06-16 1993-12-29 Gary A Siwruk John S Eynon Liquid phase synthesis of peptides and peptide derivatives
US5516891A (en) * 1992-06-16 1996-05-14 Kinerton, Ltd. Liquid phase synthesis of peptides and peptide derivatives
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
IL129728A0 (en) * 1996-11-04 2000-02-29 Dimensional Pharm Inc System method and computer program product for the visualization and interactive processing and analysis of chemical data
US6571227B1 (en) * 1996-11-04 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Method, system and computer program product for non-linear mapping of multi-dimensional data
US6453246B1 (en) 1996-11-04 2002-09-17 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing proximity data in a multi-dimensional space
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
GB9717173D0 (en) * 1997-08-13 1997-10-22 Akzo Nobel Nv Solid phase supports
US6114468A (en) * 1998-06-01 2000-09-05 Novartis Ag Synthetic resins for use in solid phase synthesis
US7416524B1 (en) 2000-02-18 2008-08-26 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method and computer program product for fast and efficient searching of large chemical libraries
WO2001065462A2 (en) 2000-02-29 2001-09-07 3-Dimensional Pharmaceuticals, Inc. Method and computer program product for designing combinatorial arrays
AU2001247627A1 (en) 2000-03-22 2001-10-03 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing object relationships in a multidimensional space
WO2001075790A2 (en) 2000-04-03 2001-10-11 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for representing object relationships in a multidimensional space
AU2001286601A1 (en) * 2000-08-22 2002-03-04 Dimitris K. Agrafiotis Method, system, and computer program product for determining properties of combinatorial library products from features of library building blocks
US6678619B2 (en) * 2000-09-20 2004-01-13 Victor S. Lobanov Method, system, and computer program product for encoding and building products of a virtual combinatorial library
WO2002061419A1 (en) * 2001-01-29 2002-08-08 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for analyzing combinatorial libraries
WO2002083606A1 (en) * 2001-04-17 2002-10-24 University Of Alberta A linker system for the synthesis and screening of combinatorial libraries of polyamine derivatives on water compatible supports
ATE321078T1 (de) * 2002-01-25 2006-04-15 Phenomenex Inc Oberflächenpfropfmodifizierte harze und deren herstellung
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
DE602004031736D1 (de) * 2003-07-04 2011-04-21 Lonza Ag Verbessertes verfahren für festphasensynthese
EP1630600A3 (en) * 2004-07-29 2006-03-22 Rohm and Haas Electronic Materials, L.L.C. Hot melt composition and method involving forming a masking pattern
US20060128939A1 (en) * 2004-12-03 2006-06-15 Vijayendra Kumar One pot process for making polymeric antioxidants
CA2761265C (en) * 2009-05-06 2017-12-19 Mallinckrodt Llc Solid support for fmoc-solid phase synthesis of peptide acids
TWI787670B (zh) 2011-12-28 2022-12-21 日商中外製藥股份有限公司 具有環狀部之胜肽化合物及其醫藥組成物
WO2015077635A2 (en) 2013-11-22 2015-05-28 Polnox Corporation Macromolecular antioxidants based on dual type moiety per molecule: structures methods of making and using the same
US20180251695A1 (en) 2017-03-01 2018-09-06 Polnox Corporation Macromolecular Corrosion (McIn) Inhibitors: Structures, Methods Of Making And Using The Same
KR20230169447A (ko) 2017-06-09 2023-12-15 추가이 세이야쿠 가부시키가이샤 N-치환 아미노산을 포함하는 펩타이드의 합성 방법
JP7411414B2 (ja) * 2017-12-15 2024-01-11 中外製薬株式会社 ペプチドの製造方法、及び塩基の処理方法
WO2020111238A1 (ja) 2018-11-30 2020-06-04 中外製薬株式会社 ペプチド化合物、またはアミド化合物の脱保護法および固相反応における脱樹脂方法、並びにペプチド化合物の製造方法
CN113692401A (zh) 2019-03-15 2021-11-23 中外制药株式会社 芳香族氨基酸衍生物的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE141977C (pt) *
GB1406611A (en) * 1971-08-17 1975-09-17 Leo Ab Pharmaceutically active secondary phosphoric acid esters
DD141977A3 (de) * 1975-07-11 1980-06-04 Jens Fischer Verfahren zur herstellung wasserunloeslicher enzym-polystyrol-komplexe
US4301045A (en) * 1977-05-02 1981-11-17 Armour Pharmaceutical Company Synthesis of peptides
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4569967A (en) * 1983-10-24 1986-02-11 The Salk Institute For Biological Studies Synthesis of N-substituted peptide amides
US4623484A (en) * 1984-05-24 1986-11-18 Research Corporation Process for peptide synthesis
GB2169901A (en) * 1984-12-11 1986-07-23 Lkb Biochrom Ltd method for a solid phase synthesis of a linear combination of amino acid residues.
US4731412A (en) * 1984-12-28 1988-03-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptide esters
US4716147A (en) * 1986-03-27 1987-12-29 Monsanto Company Synthetic airial peptides
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis

Also Published As

Publication number Publication date
ATE88726T1 (de) 1993-05-15
AU615181B2 (en) 1991-09-26
FI881451A0 (fi) 1988-03-28
FI90780C (fi) 1994-03-25
HUT46713A (en) 1988-11-28
FI881451A (fi) 1988-10-01
DK175042B1 (da) 2004-05-10
IE61485B1 (en) 1994-11-02
DE3880541D1 (de) 1993-06-03
US4859736A (en) 1989-08-22
DD284031A5 (de) 1990-10-31
KR950013679B1 (ko) 1995-11-13
PT87105B (pt) 1992-07-31
JPS63260946A (ja) 1988-10-27
HU208155B (en) 1993-08-30
US5004781A (en) 1991-04-02
YU62588A (en) 1990-10-31
DD274033A5 (de) 1989-12-06
US5093530A (en) 1992-03-03
GR3007996T3 (pt) 1993-08-31
CA1318462C (en) 1993-05-25
EP0285562B1 (de) 1993-04-28
AU1381488A (en) 1988-09-29
DD296087A5 (de) 1991-11-21
DK173088A (da) 1988-10-01
EP0285562A3 (en) 1990-01-10
EP0285562A2 (de) 1988-10-05
ES2054863T3 (es) 1994-08-16
IL85884A (en) 1992-01-15
MX10917A (es) 1993-12-01
DK173088D0 (da) 1988-03-29
KR880011210A (ko) 1988-10-27
JP2513775B2 (ja) 1996-07-03
IE880940L (en) 1988-09-30
FI90780B (fi) 1993-12-15

Similar Documents

Publication Publication Date Title
PT87105A (pt) Process for preparing a synthetic resin based on a polystyrene
DE68911280D1 (de) Flüssigphaseverfahren zur Herstellung von Methanol aus Synthesegas.
DE69133235D1 (de) Verfahren zur Herstellung von Harzen für die Feststoff-Peptidsynthese
DE69732640D1 (de) Festphasen-peptidsynthese
DE69118806D1 (de) Katalysator zur Synthese von kristallinem 3,4-Polyisopren
ATE2512T1 (de) Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung.
DE59409672D1 (de) Festphasensynthese von Oligoribonucleotiden
EP0292729A3 (en) Process for solid phase peptide synthesis
DE69205623D1 (de) Verfahren zur Herstellung von Amid durch Oximumlagerung in flüssiger Phase.
DE59105904D1 (de) Verfahren zur glycosidasekatalysierten Synthese von Glycokonjugaten.
DE69011719D1 (de) Verfahren zur Synthese von Acylamino-organosilicium-Verbindungen.
PT87749A (pt) Procede pour l'obtention de composes guanidiniques comprenant un ion tetraphenylborate substitue utilisables dans la synthese peptidique
DE69010956D1 (de) Verfahren zur Synthese von Acylaminogruppen enthaltenden Siliziumverbindungen.
DE59104538D1 (de) Verfahren zur Herstellung von Peptiden mittels Festphasensynthese.
DE69006888D1 (de) Verfahren zur Synthese von Acylamino-Organosilicon-Verbindungen.
DE59009951D1 (de) Verfahren zur Herstellung von Zwischenprodukten und zur Synthese von N-(2-Hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine.
KR840002346A (ko) 펩타이드의 제조방법
FR2616784B1 (fr) Composes guanidiniques comprenant un ion tetraphenylborate, procede d'obtention de ces composes et utilisation des composes lors de la synthese peptidique
DE69007577D1 (de) Verfahren zur Synthese von niedrigen Olefinen aus Methanol.
DE68915810D1 (de) Verfahren zur Synthese von Carboxamiden.
JPS5239670A (en) Process for synthesizing motilin
MX9207372A (es) Sal hidrocloruro de un ester alquilico de un oligopeptido o de un aminoacido y procedimiento para su preparacion.
IT1240610B (it) Nuovo derivato del 9h-xantene utile per la sintesi in fase solida di peptidi in forma di ammidi c-terminali
ES2052447A1 (es) Peptidos hemorreguladores.
ES457069A1 (es) Un metodo mejorado para preparar un polipeptido.

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920110

PC3A Transfer or assignment

Free format text: 970603 NOVARTIS AG CH

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20080328