US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
US6685940B2
(en)
*
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
US5783186A
(en)
*
|
1995-12-05 |
1998-07-21 |
Amgen Inc. |
Antibody-induced apoptosis
|
CA2246429C
(en)
*
|
1996-03-27 |
2007-07-24 |
Genentech, Inc. |
Erbb3 antibodies
|
US5968511A
(en)
*
|
1996-03-27 |
1999-10-19 |
Genentech, Inc. |
ErbB3 antibodies
|
US8038994B2
(en)
*
|
1996-05-15 |
2011-10-18 |
Quest Pharmatech Inc. |
Combination therapy for treating disease
|
BR9612619A
(pt)
*
|
1996-05-15 |
1999-07-20 |
Altarex Inc |
Método e composição para reconformar antígenos multiepitópicos para iniciar uma resposta imunológica
|
US20060159688A1
(en)
*
|
1996-05-15 |
2006-07-20 |
Ragupathy Madiyalakan |
Method for diagnosing efficacy of xenotypic antibody therapy
|
US20080220012A1
(en)
*
|
1996-05-15 |
2008-09-11 |
Ragupathy Madiyalakan |
Therapeutic Compositions that alter the immune response
|
US7371376B1
(en)
*
|
1996-10-18 |
2008-05-13 |
Genentech, Inc. |
Anti-ErbB2 antibodies
|
NZ519191A
(en)
*
|
1996-10-18 |
2005-04-29 |
Univ Texas |
Antibodies that bind to domain 1 of ErbB2 useful for inducing cell death via apoptosis, and nucleic acids encoding such antibodies
|
US6270980B1
(en)
|
1997-06-05 |
2001-08-07 |
Idun Pharmaceuticals, Inc. |
Rapid methods for identifying modifiers of cellular apoptosis activity
|
ZA9811162B
(en)
*
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
AU765003B2
(en)
*
|
1998-03-27 |
2003-09-04 |
Genentech Inc. |
Apo-2 ligand-anti-her-2 antibody synergism
|
FR2780062B1
(fr)
*
|
1998-06-17 |
2000-07-28 |
Rhone Poulenc Rorer Sa |
Anticorps monoclonaux diriges contre la proteine g3bp, et leurs utilisations
|
US7625859B1
(en)
*
|
2000-02-16 |
2009-12-01 |
Oregon Health & Science University |
HER-2 binding antagonists
|
US7393823B1
(en)
*
|
1999-01-20 |
2008-07-01 |
Oregon Health And Science University |
HER-2 binding antagonists
|
US7396810B1
(en)
*
|
2000-08-14 |
2008-07-08 |
Oregon Health Sciences University |
Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
|
ATE425749T1
(de)
|
1999-01-27 |
2009-04-15 |
Cornell Res Foundation Inc |
Behandlung von mit her-2/neu-uberexprimierung einhergehendem krebs
|
DE60039160D1
(de)
*
|
1999-04-06 |
2008-07-24 |
Genentech Inc |
Verwendung von erbb-rezeptorliganden zur behandlung von diabetes
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
EP2803367B1
(en)
|
1999-06-25 |
2018-01-31 |
ImmunoGen, Inc. |
Methods of treatment using anti-ERBB antibody-maytansinoid conjugates
|
US7041292B1
(en)
*
|
1999-06-25 |
2006-05-09 |
Genentech, Inc. |
Treating prostate cancer with anti-ErbB2 antibodies
|
EP1189634B1
(en)
*
|
1999-06-25 |
2007-02-28 |
Genentech, Inc. |
Treating prostate cancer with anti-erbb2 antibodies
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
DE60042648D1
(de)
|
1999-06-25 |
2009-09-10 |
Genentech Inc |
Humanisierte anti-erbb2 antikörper und behandlung mit anti-erbb2 antikörper
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
WO2001015730A1
(en)
*
|
1999-08-27 |
2001-03-08 |
Genentech, Inc. |
DOSAGES FOR TREATMENT WITH ANTI-ErbB2 ANTIBODIES
|
EP1229934B1
(en)
|
1999-10-01 |
2014-03-05 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
US20080124327A1
(en)
*
|
1999-10-08 |
2008-05-29 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US8048416B2
(en)
|
1999-10-08 |
2011-11-01 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US7252821B2
(en)
*
|
1999-10-08 |
2007-08-07 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US7256271B2
(en)
|
2003-01-21 |
2007-08-14 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US7442776B2
(en)
*
|
1999-10-08 |
2008-10-28 |
Young David S F |
Cancerous disease modifying antibodies
|
US20040001789A1
(en)
*
|
1999-10-08 |
2004-01-01 |
Young David S. F. |
Cytotoxicity mediation of cells evidencing surface expression of gp96 or precursors thereof
|
US7419792B2
(en)
*
|
1999-10-08 |
2008-09-02 |
Arius Research Inc. |
Laminin Receptor 1 Precursor Protein (37LRP) epitope delineated by an Hepatocellular carcinoma specific antibody
|
US7189397B2
(en)
*
|
1999-10-08 |
2007-03-13 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US6794494B1
(en)
|
2003-04-14 |
2004-09-21 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
US20040105816A1
(en)
*
|
1999-10-08 |
2004-06-03 |
Young David S. F. |
Cancerous disease modifying antibodies
|
US6180357B1
(en)
|
1999-10-08 |
2001-01-30 |
Arius Research, Inc. |
Individualized patient-specific anti-cancer antibodies
|
US7947496B2
(en)
*
|
1999-10-08 |
2011-05-24 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US20050100542A1
(en)
*
|
1999-10-08 |
2005-05-12 |
Young David S. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US6657048B2
(en)
*
|
1999-10-08 |
2003-12-02 |
Arius Research, Inc. |
Individualized anti-cancer antibodies
|
US8071072B2
(en)
*
|
1999-10-08 |
2011-12-06 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
US20090004103A1
(en)
*
|
1999-10-08 |
2009-01-01 |
Young David S F |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
EP1118334A1
(en)
*
|
2000-01-11 |
2001-07-25 |
Aventis Behring Gesellschaft mit beschränkter Haftung |
Method for the production of conjugates and uses thereof for the prevention and treatment of allergic reactions and autoimmune diseases
|
US6632979B2
(en)
|
2000-03-16 |
2003-10-14 |
Genentech, Inc. |
Rodent HER2 tumor model
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
EP1280923A2
(en)
*
|
2000-04-28 |
2003-02-05 |
Millennium Pharmaceuticals, Inc. |
14094, a human trypsin family member and uses thereof
|
KR20080038458A
(ko)
|
2000-05-19 |
2008-05-06 |
제넨테크, 인크. |
ErbB 길항제에 의한 암 치료요법에 대한 효과적인반응의 가능성을 개선시키기 위한 유전자 검출 분석
|
US7358353B2
(en)
|
2000-08-22 |
2008-04-15 |
Agensys, Inc. |
Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers
|
DK1854809T3
(da)
*
|
2000-08-22 |
2013-01-21 |
Agensys Inc |
Nukleinsyre og tilsvarende protein betegnet 158P1D7, der er anvendelig i behandling og påvisning af blærecancer og andre cancere
|
US7009040B2
(en)
*
|
2003-01-21 |
2006-03-07 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
US7442777B2
(en)
*
|
2000-11-29 |
2008-10-28 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
US7534429B2
(en)
*
|
2000-11-29 |
2009-05-19 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
US7431923B2
(en)
*
|
2005-01-03 |
2008-10-07 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
US7361343B2
(en)
*
|
2003-01-21 |
2008-04-22 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
US20060210474A1
(en)
*
|
2000-11-29 |
2006-09-21 |
Young David S |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
EP1364066A2
(en)
*
|
2001-02-02 |
2003-11-26 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Method for identifying functional nucleic acids
|
EP2075256A2
(en)
|
2002-01-14 |
2009-07-01 |
William Herman |
Multispecific binding molecules
|
WO2003074662A2
(en)
*
|
2002-03-01 |
2003-09-12 |
Exelixis, Inc. |
SCDs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
SI2289942T1
(sl)
|
2002-04-10 |
2013-11-29 |
Genentech, Inc. |
Variante protitelesa proti HER2
|
AU2003223600A1
(en)
*
|
2002-04-11 |
2003-10-27 |
Altarex Medical Corporation |
Binding agents and their use in targeting tumor cells
|
PL214010B1
(pl)
*
|
2002-07-15 |
2013-06-28 |
Genentech Inc |
Rekombinowane humanizowane przeciwcialo 2C4 i zastosowanie tego przeciwciala
|
JP4836451B2
(ja)
|
2002-07-18 |
2011-12-14 |
メルス ベー ヴェー |
抗体混合物の組換え生産
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
CA2506320A1
(en)
*
|
2002-11-21 |
2004-06-10 |
Genentech, Inc. |
Therapy of non-malignant diseases or disorders with anti-erbb2 antibodies
|
US7488475B2
(en)
|
2003-01-21 |
2009-02-10 |
Arius Research, Inc. |
Antibody therapy of tumors
|
US7361342B2
(en)
*
|
2003-01-21 |
2008-04-22 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US7468254B2
(en)
*
|
2003-01-21 |
2008-12-23 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of MCSP
|
US7175846B2
(en)
*
|
2003-01-21 |
2007-02-13 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US7393531B2
(en)
*
|
2003-01-21 |
2008-07-01 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of MCSP
|
US7195764B2
(en)
|
2003-04-14 |
2007-03-27 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US20080025977A1
(en)
*
|
2003-04-14 |
2008-01-31 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD59
|
US7399835B2
(en)
*
|
2004-02-26 |
2008-07-15 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US20060140963A1
(en)
*
|
2003-04-14 |
2006-06-29 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD59
|
US20080213169A1
(en)
*
|
2003-04-14 |
2008-09-04 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD59
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
WO2005021710A2
(en)
*
|
2003-06-02 |
2005-03-10 |
University Of Miami |
Chimeric molecules and methods of use
|
US20050232931A1
(en)
*
|
2003-06-13 |
2005-10-20 |
Oncomax Acquisition Corp. |
Preparation and application of anti-tumor bifunctional fusion proteins
|
US20040254108A1
(en)
*
|
2003-06-13 |
2004-12-16 |
Jing Ma |
Preparation and application of anti-tumor bifunctional fusion proteins
|
PT1648998E
(pt)
|
2003-07-18 |
2014-11-04 |
Amgen Inc |
Agentes de ligação específica ao factor de crescimento do hepatócito
|
US20050027106A1
(en)
*
|
2003-07-28 |
2005-02-03 |
Young David S. F. |
Cancerous disease modifying antibodies
|
US20050079184A1
(en)
*
|
2003-08-08 |
2005-04-14 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
AU2004316290C1
(en)
|
2003-11-06 |
2012-02-02 |
Seagen Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
EP1737971B1
(en)
|
2004-01-20 |
2017-08-16 |
Merus N.V. |
Mixtures of binding proteins
|
US7348413B2
(en)
*
|
2004-02-26 |
2008-03-25 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US20050255041A1
(en)
*
|
2004-05-13 |
2005-11-17 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
EP2286844A3
(en)
|
2004-06-01 |
2012-08-22 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
SV2006002143A
(es)
*
|
2004-06-16 |
2006-01-26 |
Genentech Inc |
Uso de un anticuerpo para el tratamiento del cancer resistente al platino
|
CA2568952C
(en)
|
2004-06-18 |
2019-05-21 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
KR20180091967A
(ko)
*
|
2004-07-22 |
2018-08-16 |
제넨테크, 인크. |
Her2 항체 조성물
|
CN101052654A
(zh)
*
|
2004-08-19 |
2007-10-10 |
健泰科生物技术公司 |
具有改变的效应子功能的多肽变体
|
CA2521973C
(en)
*
|
2004-09-29 |
2013-12-10 |
Tir Systems Ltd. |
System and method for controlling luminaires
|
EP1807106A2
(en)
*
|
2004-10-05 |
2007-07-18 |
Oregon Health and Science University |
Compositions and methods for treating disease
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
AU2005314127A1
(en)
*
|
2004-12-07 |
2006-06-15 |
Genentech, Inc. |
Selecting patients for therapy with a HER inhibitor
|
CN101098891B
(zh)
|
2005-01-05 |
2014-05-21 |
F-星生物技术研究与开发有限公司 |
分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域
|
KR20150083139A
(ko)
*
|
2005-01-21 |
2015-07-16 |
제넨테크, 인크. |
Her 항체의 고정 용량 투여법
|
ZA200706247B
(en)
*
|
2005-02-09 |
2008-11-26 |
Genentech Inc |
Inhibiting HER2 shedding with matrix metalloprotease antagonists
|
RS53128B
(en)
*
|
2005-02-23 |
2014-06-30 |
Genentech Inc. |
Extending the time of disease progression or survival in patients with ovarian cancers using PERTUZUMAB
|
US20060204505A1
(en)
*
|
2005-03-08 |
2006-09-14 |
Sliwkowski Mark X |
Methods for identifying tumors responsive to treatment with HER dimerization inhibitors (HDIs)
|
JP2006316040A
(ja)
|
2005-05-13 |
2006-11-24 |
Genentech Inc |
Herceptin(登録商標)補助療法
|
US7452979B2
(en)
|
2005-08-02 |
2008-11-18 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
US7494648B2
(en)
*
|
2005-08-02 |
2009-02-24 |
Hoffmann-La Roche Inc. |
Cancerous disease modifying antibodies
|
US7411046B2
(en)
|
2005-08-02 |
2008-08-12 |
Arius Research Inc |
Cancerous disease modifying antibodies
|
US7456258B2
(en)
|
2005-08-02 |
2008-11-25 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
US7456259B2
(en)
|
2005-08-02 |
2008-11-25 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
US7452978B2
(en)
|
2005-08-02 |
2008-11-18 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
FR2895086B1
(fr)
*
|
2005-12-16 |
2012-10-05 |
Lab Francais Du Fractionnement |
Potentialisation de l'apoptose par des anticorps monoclonaux
|
US20080305104A1
(en)
*
|
2006-02-24 |
2008-12-11 |
Young David S F |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
US20080213267A1
(en)
*
|
2006-02-24 |
2008-09-04 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
WO2007095745A1
(en)
*
|
2006-02-24 |
2007-08-30 |
Arius Research Inc. |
Cancerous disease modifying antibody 141205-02
|
WO2007095746A1
(en)
|
2006-02-24 |
2007-08-30 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
US7420041B2
(en)
*
|
2006-02-24 |
2008-09-02 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
US20080089891A1
(en)
*
|
2006-07-26 |
2008-04-17 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
PL2511301T3
(pl)
|
2006-08-04 |
2018-05-30 |
Medimmune Limited |
Ludzkie przeciwciała do ErbB2
|
KR20090101885A
(ko)
*
|
2006-11-13 |
2009-09-29 |
에프. 호프만-라 로슈 아게 |
암 질환 조절 항체
|
EP2089514A1
(en)
*
|
2006-11-13 |
2009-08-19 |
Arius Research Inc. |
Cancerous disease modifying antibodies
|
BRPI0718644A2
(pt)
*
|
2006-11-13 |
2013-11-26 |
Arius Res Inc |
Anticorpo monoclonal isolado, anticorpos humanizado e quimérico do anticorpo monoclonal isolado, linha de célula hibridoma isolada, método para iniciar a citotoxidez induzida por anticorpo de células cancerosas em uma amostra de tecido selecionada de um tumor humano, cdmab do anticorpo monoclonal isolado ou seu cdmab e usos de um anticorpo monoclonal ou seu cdmab, sozinho ou em conjução com pelo menos um agente quimioterapêutico, e composição
|
US8003761B2
(en)
|
2007-01-23 |
2011-08-23 |
Hoffmann-La Roche Inc. |
Cancerous disease modifying antibodies
|
US20080206133A1
(en)
*
|
2007-01-23 |
2008-08-28 |
Young David S F |
Cancerous Disease Modifying Antibodies
|
AU2008223069B2
(en)
|
2007-03-02 |
2012-12-13 |
F. Hoffmann-La Roche Ag |
Predicting response to a HER dimerisation inhibitor based on low HER3 expression
|
CA2681144A1
(en)
*
|
2007-03-26 |
2008-10-02 |
F. Hoffmann-La Roche Ag |
Cancer disease modifying antibody 010207-01 produced by hybridoma cell line ar51a630.3.
|
CN101688183A
(zh)
*
|
2007-05-07 |
2010-03-31 |
霍夫曼-拉罗奇有限公司 |
减轻癌性疾病的抗体
|
US20090258005A1
(en)
*
|
2007-05-29 |
2009-10-15 |
Trubion Pharmaceuticals Inc. |
Therapeutic compositions and methods
|
US20090304590A1
(en)
*
|
2007-05-29 |
2009-12-10 |
Wyeth |
Therapeutic compositions and methods
|
US9551033B2
(en)
*
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
EP2592156B1
(en)
|
2007-06-08 |
2016-04-20 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
CN101802006B
(zh)
|
2007-06-26 |
2013-08-14 |
F-星生物技术研究与开发有限公司 |
展示结合剂
|
DK3597659T5
(da)
|
2007-07-09 |
2024-09-02 |
Genentech Inc |
Forhindring af disulfidbindingsreduktion under rekombinant produktion af polypeptider
|
CN101802013B
(zh)
|
2007-07-16 |
2014-07-02 |
健泰科生物技术公司 |
人源化抗cd79b抗体和免疫偶联物及使用方法
|
SI2474557T1
(sl)
|
2007-07-16 |
2014-12-31 |
Genentech, Inc. |
Protiteles proti CD79b in imunokonjugati in postopki za uporabo
|
NZ586544A
(en)
*
|
2007-12-26 |
2012-07-27 |
Vaccinex Inc |
Anti-c35 antibody in combination with an ani-her2 antibody in cancer therapies and methods
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
EP2237797A4
(en)
|
2008-01-03 |
2012-11-07 |
Scripps Research Inst |
ANTIBODY TARGETING BY MODULAR DETECTION DOMAIN
|
US20090191197A1
(en)
*
|
2008-01-28 |
2009-07-30 |
Young David S F |
Cancerous disease modifying antibodies
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
EP2247620B1
(en)
|
2008-01-31 |
2016-05-18 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
CA2716592C
(en)
|
2008-03-18 |
2018-02-27 |
Genentech, Inc. |
Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
|
WO2009124381A1
(en)
*
|
2008-04-10 |
2009-10-15 |
F. Hoffmann-La Roche Ag |
An anti-cancer cytotoxic monoclonal antibody
|
PL3514180T3
(pl)
|
2008-04-11 |
2024-08-12 |
Chugai Seiyaku Kabushiki Kaisha |
Cząsteczka wiążąca antygen zdolna do wiązania dwóch lub więcej cząsteczek antygenu w sposób powtarzalny
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
JP2011520923A
(ja)
*
|
2008-05-19 |
2011-07-21 |
武田薬品工業株式会社 |
細胞傷害性抗癌モノクローナル抗体
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
CA2731129A1
(en)
*
|
2008-07-17 |
2010-01-21 |
Helen P. Findlay |
Cancerous disease modifying antibodies
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
CN102753193A
(zh)
*
|
2008-10-31 |
2012-10-24 |
比奥根艾迪克Ma公司 |
Light靶向分子及其用途
|
HUE060624T2
(hu)
|
2009-02-13 |
2023-04-28 |
Immunomedics Inc |
Sejten belüli hasítható kötést tartalmazó immunkonjugátumok
|
PE20120539A1
(es)
|
2009-03-20 |
2012-05-12 |
Genentech Inc |
Anticuerpos anti-her biespecifico
|
SG176073A1
(en)
|
2009-05-29 |
2011-12-29 |
Hoffmann La Roche |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
WO2011004899A1
(en)
|
2009-07-06 |
2011-01-13 |
Takeda Pharmaceutical Company Limited |
Cancerous disease modifying antibodies
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
MX2012001742A
(es)
|
2009-08-11 |
2012-03-21 |
Genentech Inc |
Produccion de proteinas en medios de cultivo de celulas libres de glutamina.
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
US8287865B2
(en)
|
2009-09-16 |
2012-10-16 |
Immunomedics, Inc. |
Class I anti-CEA antibodies and uses thereof
|
WO2011068845A1
(en)
|
2009-12-02 |
2011-06-09 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
AU2011218125A1
(en)
|
2010-02-18 |
2012-07-19 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
KR20130108069A
(ko)
|
2010-04-15 |
2013-10-02 |
알퍼 바이오테크, 엘엘씨 |
Her2 항원에 대한 모노클로날 항체 및 그를 위한 용도
|
US9328024B2
(en)
|
2010-04-29 |
2016-05-03 |
The Regents Of The University Of California |
Application of high toughness, low viscosity nano-molecular resin for reinforcing pothole patching materials in asphalt and concrete base pavement
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
EP2407487A1
(en)
|
2010-07-14 |
2012-01-18 |
F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. |
Multispecific modular antibody
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
US20130245233A1
(en)
|
2010-11-24 |
2013-09-19 |
Ming Lei |
Multispecific Molecules
|
TWI812066B
(zh)
|
2010-11-30 |
2023-08-11 |
日商中外製藥股份有限公司 |
具有鈣依存性的抗原結合能力之抗體
|
CA2820095C
(en)
|
2010-12-21 |
2019-02-26 |
F. Hoffmann-La Roche Ag |
Isoform enriched antibody preparation and method for obtaining it
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
WO2012115241A1
(ja)
|
2011-02-25 |
2012-08-30 |
中外製薬株式会社 |
FcγRIIb特異的Fc抗体
|
WO2012122512A1
(en)
|
2011-03-10 |
2012-09-13 |
Hco Antibody, Inc. |
Recombinant production of mixtures of single chain antibodies
|
EP2704751B1
(en)
|
2011-05-02 |
2019-04-17 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
CN106432506A
(zh)
|
2011-05-24 |
2017-02-22 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
EP2546268A1
(en)
|
2011-07-13 |
2013-01-16 |
F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. |
Internalising immunoglobulin
|
KR20140057326A
(ko)
|
2011-08-17 |
2014-05-12 |
제넨테크, 인크. |
뉴레귤린 항체 및 그의 용도
|
EP2751285B2
(en)
|
2011-08-31 |
2020-04-01 |
Genentech, Inc. |
Method for sensitivity testing of a tumour for a egfr kinase inhibitor
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
WO2013063229A1
(en)
*
|
2011-10-25 |
2013-05-02 |
The Regents Of The University Of Michigan |
Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
|
CA2857114A1
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
EP2788500A1
(en)
|
2011-12-09 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
AU2013240261A1
(en)
|
2012-03-27 |
2014-09-18 |
Genentech, Inc. |
Diagnosis and treatments relating to HER3 inhibitors
|
CA2871068C
(en)
|
2012-04-20 |
2022-06-14 |
Merus B.V. |
Methods and means for the production of ig-like molecules
|
EP2885002A4
(en)
|
2012-08-14 |
2016-04-20 |
Ibc Pharmaceuticals Inc |
BISPECIFIC ANTIBODIES REDIRECTED AGAINST T CELLS FOR THE TREATMENT OF DISEASES
|
PT2887959T
(pt)
|
2012-08-23 |
2019-02-01 |
Seattle Genetics Inc |
Conjugados anticorpo-fármaco (adc) que se ligam a proteínas 158p1d7
|
AU2013337926B2
(en)
|
2012-10-30 |
2017-12-21 |
Esperance Pharmaceuticals, Inc. |
Antibody/drug conjugates and methods of use
|
BR112015012644A2
(pt)
|
2012-11-30 |
2017-12-19 |
Hoffmann La Roche |
método para determinar a necessidade de um paciente com câncer, método de tratamento do câncer, composição farmacêutica, uso de um ácido nucleico ou anticorpo e kit;
|
CN118001422A
(zh)
|
2012-12-13 |
2024-05-10 |
免疫医疗公司 |
功效改进且毒性降低的抗体与sn-38的免疫缀合物的剂量
|
CN105451767B
(zh)
|
2013-03-15 |
2019-10-18 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
KR101453462B1
(ko)
|
2013-05-16 |
2014-10-23 |
앱클론(주) |
Her2에 특이적으로 결합하는 항체
|
CN106132436B
(zh)
|
2014-02-21 |
2021-06-15 |
Ibc药品公司 |
通过诱导对trop-2表达细胞的免疫应答的疾病疗法
|
WO2015130416A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
WO2015157399A1
(en)
|
2014-04-10 |
2015-10-15 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Transgene genetic tags and methods of use
|
CA2943299A1
(en)
|
2014-04-11 |
2015-10-15 |
Medimmune, Llc |
Bispecific her2 antibodies
|
CN106456784A
(zh)
|
2014-04-16 |
2017-02-22 |
拜康有限公司 |
包含摩尔过量的山梨醇的稳定蛋白质制剂
|
US9580495B2
(en)
|
2014-06-24 |
2017-02-28 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
US20160082120A1
(en)
|
2014-09-23 |
2016-03-24 |
Genentech, Inc. |
METHODS OF USING ANTI-CD79b IMMUNOCONJUGATES
|
EP3954373A1
(en)
|
2014-10-07 |
2022-02-16 |
Immunomedics, Inc. |
Neoadjuvant use of antibody-drug conjugates
|
SG11201607165YA
(en)
|
2014-12-19 |
2016-09-29 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
AR103161A1
(es)
|
2014-12-19 |
2017-04-19 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos antimiostatina y regiones fc variantes así como métodos de uso
|
AU2016216079A1
(en)
|
2015-02-05 |
2017-07-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antibodies comprising an ion concentration dependent antigen-binding domain, Fc region variants, IL-8-binding antibodies, and uses therof
|
CA2972393A1
(en)
|
2015-02-27 |
2016-09-01 |
Chugai Seiyaku Kabushiki Kaisha |
Composition for treating il-6-related diseases
|
WO2016172427A1
(en)
|
2015-04-22 |
2016-10-27 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
SMT202000226T1
(it)
|
2015-05-30 |
2020-05-08 |
Molecular Templates Inc |
Impalcatura di subunita' a della tossina shiga de-immunizzate e molecole di targeting cellulare comprendenti la stessa
|
KR20180012859A
(ko)
*
|
2015-06-17 |
2018-02-06 |
제넨테크, 인크. |
항-her2 항체 및 이용 방법
|
AU2016281622C1
(en)
|
2015-06-25 |
2021-11-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
SI3316885T1
(sl)
|
2015-07-01 |
2021-09-30 |
Immunomedics, Inc. |
Imunokonjugati protitelo-SN-38 z linkerjem CL2A
|
US11458167B2
(en)
|
2015-08-07 |
2022-10-04 |
Seattle Children's Hospital |
Bispecific CAR T-cells for solid tumor targeting
|
US11359009B2
(en)
|
2015-12-25 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
US20190151346A1
(en)
|
2016-05-10 |
2019-05-23 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
TW202300168A
(zh)
|
2016-08-05 |
2023-01-01 |
日商中外製藥股份有限公司 |
Il-8相關疾病之治療用或預防用組成物
|
MX2019006631A
(es)
|
2016-12-12 |
2019-11-12 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Variantes quimericas de factores de transcripcion con sensibilidad aumentada a induccion por ligando de farmaco de expresion transgenica en celulas mamiferas.
|
SMT202000640T1
(it)
|
2017-01-17 |
2021-01-05 |
Hoffmann La Roche |
Formulazioni sottocutanee di anticorpo her2
|
JP7191833B2
(ja)
|
2017-01-30 |
2022-12-19 |
中外製薬株式会社 |
抗スクレロスチン抗体およびその使用
|
WO2018158716A1
(en)
|
2017-03-02 |
2018-09-07 |
Cadila Healthcare Limited |
Novel protein drug conjugate formulation
|
EP3589661B1
(en)
|
2017-03-02 |
2023-11-01 |
Genentech, Inc. |
Adjuvant treatment of her2-positive breast cancer
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
EP3712178A4
(en)
|
2017-11-14 |
2021-08-11 |
Green Cross Lab Cell Corporation |
ANTI-HER2 ANTIBODIES OR ANTIGIBODY FRAGMENT THEREOF AND CHIMERAIR ANTIGEN RECEPTOR WITH IT
|
SG10201801219VA
(en)
|
2018-02-13 |
2019-09-27 |
Agency Science Tech & Res |
Anti-HER2 Antibodies
|
CN110612117B
(zh)
|
2018-04-17 |
2024-04-12 |
分子模板公司 |
包含去免疫化的志贺毒素a亚基支架的her2靶向分子
|
EP3560945A1
(en)
|
2018-04-27 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Methods for purification of polypeptides using polysorbates
|
CA3187272A1
(en)
|
2020-10-08 |
2022-04-14 |
Thorsten Ross |
Trispecific binders
|
JPWO2022239720A1
(pt)
|
2021-05-10 |
2022-11-17 |
|
|
IL308154A
(en)
|
2021-07-30 |
2023-12-01 |
Affimed Gmbh |
Double structure antibodies
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
MX2024005106A
(es)
|
2021-11-03 |
2024-07-02 |
Affimed Gmbh |
Ligandos biespecificos de cd16a.
|
GB202309703D0
(en)
|
2023-06-27 |
2023-08-09 |
Epsilogen Ltd |
Composition
|