PT845032E - Moleculas isoladas de acidos nucleicos peptidos que formam complexos com a molecula a2-alh do cph e suas aplicacoes - Google Patents
Moleculas isoladas de acidos nucleicos peptidos que formam complexos com a molecula a2-alh do cph e suas aplicacoesInfo
- Publication number
- PT845032E PT845032E PT96913954T PT96913954T PT845032E PT 845032 E PT845032 E PT 845032E PT 96913954 T PT96913954 T PT 96913954T PT 96913954 T PT96913954 T PT 96913954T PT 845032 E PT845032 E PT 845032E
- Authority
- PT
- Portugal
- Prior art keywords
- molecula
- cph
- alh
- applications
- nucleic acids
- Prior art date
Links
- 108091093037 Peptide nucleic acid Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 4
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 239000002243 precursor Substances 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/487,135 US5821122A (en) | 1995-06-07 | 1995-06-07 | Isolated nucleic acid molecules, peptides which form complexes with MHC molecule HLA-A2 and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PT845032E true PT845032E (pt) | 2002-05-31 |
Family
ID=23934549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96913954T PT845032E (pt) | 1995-06-07 | 1996-05-07 | Moleculas isoladas de acidos nucleicos peptidos que formam complexos com a molecula a2-alh do cph e suas aplicacoes |
Country Status (12)
Country | Link |
---|---|
US (3) | US5821122A (pt) |
EP (1) | EP0845032B1 (pt) |
JP (1) | JP3849102B2 (pt) |
AT (1) | ATE209680T1 (pt) |
AU (1) | AU704934B2 (pt) |
CA (1) | CA2223694C (pt) |
DE (1) | DE69617440T2 (pt) |
DK (1) | DK0845032T3 (pt) |
ES (1) | ES2167561T3 (pt) |
PT (1) | PT845032E (pt) |
WO (1) | WO1996040039A2 (pt) |
ZA (1) | ZA963907B (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6042198A (en) | 1997-01-27 | 1998-08-18 | Ludwig Institute For Cancer Research | Lage-1 tumor associated nucleic acids |
US6680191B1 (en) | 1997-04-25 | 2004-01-20 | Ludwig Institute For Cancer | Isolated nucleic acid molecules coding for tumor rejection antigen precursors of members of the MAGE-C and MAGE-B FAMILIES and uses thereof |
US6734172B2 (en) | 1998-11-18 | 2004-05-11 | Pacific Northwest Research Institute | Surface receptor antigen vaccines |
US20020164654A1 (en) * | 2000-01-20 | 2002-11-07 | Rosalie Luiten | MAGE antigenic peptides which bind HLA-B35 and HLA-B44 |
ES2331348T3 (es) | 2000-09-15 | 2009-12-30 | Pasteur Institut | Vectores proteinicos para el suministro de moleculas a las celulas que expresan cd11b. |
US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
IL156955A0 (en) | 2001-01-17 | 2004-02-08 | Genecraft Inc | Binding domain-immunoglobulin fusion proteins |
US6607151B2 (en) * | 2001-08-16 | 2003-08-19 | Morris Samelson | Ultra fine dead sea mineral compound and method of manufacture |
WO2003063792A2 (en) | 2002-01-30 | 2003-08-07 | The Brigham And Women's Hospital, Inc. | Compositions and methods related to tim-3, a th1-specific cell surface molecule |
US20070026022A1 (en) * | 2004-11-19 | 2007-02-01 | Gilles Dadaglio | Recombinant adenylate cyclase toxin of Bordetella induces T cell responses against tumoral antigens |
EP1684801B1 (en) * | 2003-11-21 | 2009-12-02 | Institut Pasteur | Recombinant adenylate cyclase toxin of bordetella induces t cell responses against tumoral antigens |
KR20070056042A (ko) * | 2004-06-17 | 2007-05-31 | 맨카인드 코포레이션 | 에피토프 유사체 |
WO2006083305A2 (en) | 2004-06-23 | 2006-08-10 | University Of Texas System | Methods and compositions for the detection of biological molecules using a two particle complex |
US8481297B2 (en) | 2009-01-08 | 2013-07-09 | Yale University | Compositions and methods of use of an oncolytic vesicular stomatitis virus |
WO2011032003A1 (en) | 2009-09-10 | 2011-03-17 | Yale University | Immunization to reduce neurotoxicity during treatment with cytolytic viruses |
WO2011056993A1 (en) | 2009-11-04 | 2011-05-12 | Yale University | Compositions and methods for treating cancer with attenuated oncolytic viruses |
JP2015519909A (ja) | 2012-06-15 | 2015-07-16 | アダプティブ バイオテクノロジーズ コーポレイション | 複合遺伝子セットにおける固有にタグ付加された再構成適応性免疫受容体遺伝子 |
CA2906218A1 (en) | 2013-03-15 | 2014-09-18 | Adaptive Biotechnologies Corporation | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
US10874621B2 (en) | 2013-10-17 | 2020-12-29 | The Brigham And Women's Hospital, Inc. | Cationic nanoparticles for co-delivery of nucleic acids and therapeutic agents |
WO2015172153A1 (en) | 2014-05-09 | 2015-11-12 | Yale University | Topical formulation of hyperbranched polyglycerol-coated particles thereof |
US20180126014A1 (en) | 2015-04-15 | 2018-05-10 | Yale University | Compositions for enhancing delivery of agents across the blood brain barrier and methods of use thereof |
WO2017095751A1 (en) | 2015-12-02 | 2017-06-08 | Partikula Llc | Compositions and methods for modulating cancer cell metabolism |
US20190117799A1 (en) | 2016-04-01 | 2019-04-25 | The Brigham And Women's Hospital, Inc. | Stimuli-responsive nanoparticles for biomedical applications |
JP2019533645A (ja) | 2016-09-16 | 2019-11-21 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 標的組織および細胞内送達のための増大した粘膜浸透のタンパク質ナノケージ |
WO2018112470A1 (en) | 2016-12-16 | 2018-06-21 | The Brigham And Women's Hospital, Inc. | Co-delivery of nucleic acids for simultaneous suppression and expression of target genes |
US20230140818A1 (en) | 2017-04-27 | 2023-05-04 | The University Of Hong Kong | Use of hcn inhibitors for treatment of cancer |
US11478433B2 (en) | 2017-06-23 | 2022-10-25 | Yale University | Nanomaterials with enhanced drug delivery efficiency |
EP4377338A2 (en) | 2021-07-27 | 2024-06-05 | Novab, Inc. | Engineered vlrb antibodies with immune effector functions |
EP4444358A1 (en) | 2021-12-08 | 2024-10-16 | Yale University | Surface conjugation to poly(amine-co-ester) nanoparticles for targeting to cells and tissues |
KR20240145481A (ko) | 2022-01-28 | 2024-10-07 | 유니버시티 오브 조지아 리서치 파운데이션, 인코포레이티드 | 방사선 민감화 조성물 및 이의 사용 방법 |
WO2024050524A1 (en) | 2022-09-01 | 2024-03-07 | University Of Georgia Research Foundation, Inc. | Compositions and methods for directing apolipoprotein l1 to induce mammalian cell death |
WO2024112867A1 (en) | 2022-11-23 | 2024-05-30 | University Of Georgia Research Foundation, Inc. | Compositions and methods of use thereof for increasing immune responses |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5342774A (en) * | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
DE69329656T2 (de) * | 1992-12-22 | 2001-06-28 | Ludwig Institute For Cancer Research, New York | Methoden zur detektion und behandlung von individuen mit abnormalen hla-a2/tyrosinase-peptidantigenen exprimierenden zellen |
US5620886A (en) * | 1993-03-18 | 1997-04-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5856091A (en) * | 1993-03-18 | 1999-01-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5554724A (en) * | 1994-03-24 | 1996-09-10 | University Of Leiden | Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof |
US5851523A (en) * | 1994-03-24 | 1998-12-22 | Ludwig Institute For Cancer Research. | Isolated, peptides derived from MAGE tumor rejection antigen precursors which complex with HLA-A2 molecules and uses thereof |
US5997870A (en) * | 1994-06-03 | 1999-12-07 | Ludwig Institute For Cancer Research | Isolated peptides which bind to HLA-B44 Molecules |
-
1995
- 1995-06-07 US US08/487,135 patent/US5821122A/en not_active Expired - Lifetime
-
1996
- 1996-05-07 PT PT96913954T patent/PT845032E/pt unknown
- 1996-05-07 WO PCT/US1996/006409 patent/WO1996040039A2/en active IP Right Grant
- 1996-05-07 AT AT96913954T patent/ATE209680T1/de active
- 1996-05-07 DK DK96913954T patent/DK0845032T3/da active
- 1996-05-07 AU AU56769/96A patent/AU704934B2/en not_active Expired
- 1996-05-07 CA CA002223694A patent/CA2223694C/en not_active Expired - Lifetime
- 1996-05-07 EP EP96913954A patent/EP0845032B1/en not_active Expired - Lifetime
- 1996-05-07 DE DE69617440T patent/DE69617440T2/de not_active Expired - Lifetime
- 1996-05-07 JP JP50052197A patent/JP3849102B2/ja not_active Expired - Lifetime
- 1996-05-07 ES ES96913954T patent/ES2167561T3/es not_active Expired - Lifetime
- 1996-05-16 ZA ZA963907A patent/ZA963907B/xx unknown
-
1997
- 1997-08-21 US US08/915,972 patent/US5886145A/en not_active Expired - Lifetime
-
1998
- 1998-10-23 US US09/177,909 patent/US5958711A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0845032B1 (en) | 2001-11-28 |
JP3849102B2 (ja) | 2006-11-22 |
AU5676996A (en) | 1996-12-30 |
ZA963907B (en) | 1997-03-11 |
DK0845032T3 (da) | 2002-05-06 |
ES2167561T3 (es) | 2002-05-16 |
US5886145A (en) | 1999-03-23 |
US5958711A (en) | 1999-09-28 |
CA2223694C (en) | 2003-06-24 |
EP0845032A4 (en) | 2000-05-10 |
ATE209680T1 (de) | 2001-12-15 |
US5821122A (en) | 1998-10-13 |
DE69617440D1 (de) | 2002-01-10 |
DE69617440T2 (de) | 2002-08-08 |
EP0845032A2 (en) | 1998-06-03 |
JP2001520506A (ja) | 2001-10-30 |
CA2223694A1 (en) | 1996-12-19 |
WO1996040039A2 (en) | 1996-12-19 |
AU704934B2 (en) | 1999-05-06 |
WO1996040039A3 (en) | 2000-03-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT845032E (pt) | Moleculas isoladas de acidos nucleicos peptidos que formam complexos com a molecula a2-alh do cph e suas aplicacoes | |
FI956019A0 (fi) | Eristettyjä peptidejä, jotka muodostavat komplekseja MHC-molekyyli HLA-C-klooni-10:n kanssa, ja niiden käyttö | |
ZA958039B (en) | Isolated nucleic acid molecule coding for tumor rejection antigen precursor dage and uses thereof | |
FI960268A (fi) | Menetelmä sairauden diagnosoimiseksi määrittämällä GAGE-tuumorihyljintäantigeenin prekursorien ilmentymistä | |
ATE258379T1 (de) | Nukleinsäure, die für einen tumor abstossungsantigenvorläufer kodiert | |
ES2192602T3 (es) | Molecula de acido nucleico aislada y truncada, que codifica el antigeno de rechazo tumurall gage. | |
NZ332369A (en) | Isolated nucleic acid molecules which code for GAGE tumor rejection antigen, the tumor rejection antigen, and uses thereof | |
TW372973B (en) | Isolated, truncated nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof | |
HUP0004739A1 (hu) | Presenilinekkel kölcsönhatásra képes fehérjéket kódoló nukleinsavak | |
PT914417E (pt) | Dnase ii humana | |
CA2213001A1 (en) | Isolated nucleic acid molecule encoding peptides which form complexes with mhc molecule hla-cw*1601 and uses thereof |