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PT3720879T - Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro - Google Patents

Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro

Info

Publication number
PT3720879T
PT3720879T PT188297428T PT18829742T PT3720879T PT 3720879 T PT3720879 T PT 3720879T PT 188297428 T PT188297428 T PT 188297428T PT 18829742 T PT18829742 T PT 18829742T PT 3720879 T PT3720879 T PT 3720879T
Authority
PT
Portugal
Prior art keywords
immunotherapy
combination therapy
treat cancer
progastrin antibody
progastrin
Prior art date
Application number
PT188297428T
Other languages
English (en)
Original Assignee
Progastrine Et Cancers S A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progastrine Et Cancers S A R L filed Critical Progastrine Et Cancers S A R L
Publication of PT3720879T publication Critical patent/PT3720879T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT188297428T 2017-12-05 2018-12-05 Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro PT3720879T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762594755P 2017-12-05 2017-12-05

Publications (1)

Publication Number Publication Date
PT3720879T true PT3720879T (pt) 2022-07-13

Family

ID=64949216

Family Applications (1)

Application Number Title Priority Date Filing Date
PT188297428T PT3720879T (pt) 2017-12-05 2018-12-05 Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro

Country Status (14)

Country Link
US (2) US11046758B2 (pt)
EP (1) EP3720879B1 (pt)
JP (1) JP7104153B2 (pt)
KR (1) KR102461238B1 (pt)
CN (1) CN111670197A (pt)
AU (1) AU2018379320B2 (pt)
CA (1) CA3084687C (pt)
DK (1) DK3720879T3 (pt)
ES (1) ES2920283T3 (pt)
PL (1) PL3720879T3 (pt)
PT (1) PT3720879T (pt)
SG (1) SG11202005296SA (pt)
TW (1) TWI763956B (pt)
WO (1) WO2019110662A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111670197A (zh) * 2017-12-05 2020-09-15 普莱戈斯瑞恩癌症有限责任公司 治疗癌症的抗前胃泌激素抗体与免疫疗法的组合疗法
JP7485274B2 (ja) * 2018-02-27 2024-05-16 イー、シー、エス、プロガストリン、エス、エー 免疫療法のためのバイオマーカーとしてのプロガストリン
CN111171146B (zh) * 2020-02-20 2022-03-04 西北农林科技大学 抗h9n2亚型禽流感病毒的纳米抗体、制备方法和应用
US20240287184A1 (en) * 2021-06-11 2024-08-29 Guangdong Fapon Biopharma Inc. Anti-pd-1 humanized antibody or antigen-binding fragment thereof and application thereof

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4716111A (en) 1982-08-11 1987-12-29 Trustees Of Boston University Process for producing human antibodies
US4975278A (en) 1988-02-26 1990-12-04 Bristol-Myers Company Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
GB8924581D0 (en) 1989-11-01 1989-12-20 Pa Consulting Services Bleaching of hair
DK0463151T3 (da) 1990-01-12 1996-07-01 Cell Genesys Inc Frembringelse af xenogene antistoffer
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5546806A (en) 1991-10-17 1996-08-20 Kain; Aron Z. Microwave vector displacement and acceleration transducer
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化ｂ−ｂ１０
ZA932522B (en) 1992-04-10 1993-12-20 Res Dev Foundation Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5474896A (en) 1992-05-05 1995-12-12 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
RU2139731C1 (ru) 1992-11-13 1999-10-20 Айдек Фармасьютикалс Корпорейшн (US Способ лечения, антитела, гибридома
CA2761116A1 (en) 1995-04-27 1996-10-31 Amgen Fremont Inc. Human antibodies derived from immunized xenomice
CA2219486A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5830729A (en) 1996-04-18 1998-11-03 Institut Pasteur I Sce I-induced gene replacement and gene conversion in embryonic stem cells
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
DK0942968T3 (da) 1996-12-03 2008-06-23 Amgen Fremont Inc Fuldt humane antistoffer, der binder EGFR
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
EP0970126B1 (en) 1997-04-14 2001-04-18 Micromet AG Novel method for the production of antihuman antigen receptors and uses thereof
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
JP4436130B2 (ja) 2001-09-14 2010-03-24 セレクティス インビトロ直鎖化によるポリヌクレオチドのランダム組込
EP1391213A1 (en) 2002-08-21 2004-02-25 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
EP2522723B1 (en) 2003-01-28 2014-12-03 Cellectis Custom-made meganuclease and use thereof
DK1794586T3 (da) 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
US8936936B2 (en) 2007-10-25 2015-01-20 Sangamo Biosciences, Inc. Methods and compositions for targeted integration
KR101640520B1 (ko) * 2009-10-16 2016-07-19 르 라보레또레 쎄르비에르 프로가스트린에 대한 모노클로날 항체 및 이들의 용도
US9487582B2 (en) 2010-01-08 2016-11-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for treating pancreatic cancer
US9217032B2 (en) 2010-01-08 2015-12-22 Les Laboratoires Servier Methods for treating colorectal cancer
WO2011116954A2 (en) 2010-03-24 2011-09-29 Bioréalités S.A.S. Prophylaxis of colorectal and gastrointestinal cancer
KR101576174B1 (ko) 2010-07-26 2015-12-09 르 라보레또레 쎄르비에르 간암 요법을 위한 방법 및 조성물
JOP20200094A1 (ar) * 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
CN107567336B (zh) 2014-10-29 2021-12-31 戊瑞治疗有限公司 癌症的联合治疗
KR102197478B1 (ko) * 2015-12-31 2021-01-04 프로가스트린 에 캔서스 에스.에이 알.엘. 식도암을 검출 및 치료하기 위한 조성물 및 방법
EP3397966B1 (en) * 2015-12-31 2021-09-29 Progastrine et Cancers S.à r.l. Compositions and methods for detecting and treating gastric cancer
JP6962920B2 (ja) * 2015-12-31 2021-11-05 プロガストリン、エ、カンセル、エス、アー エル、エルProgastrine Et Cancers S.A R.L. 卵巣癌の検出および治療のための組成物および方法
WO2018178364A1 (en) * 2017-03-30 2018-10-04 Progastrine Et Cancers S.À R.L. Compositions and methods for treating lung cancer
CA3058263C (en) * 2017-03-30 2023-08-01 Ecs-Progastrin Sa Compositions and methods for detecting prostate cancer
KR20200015943A (ko) * 2017-06-15 2020-02-13 캔설 어드밴스 아이엔씨 종양 및 암에 대한 체액성 및 세포 면역을 유도하기 위한 조성물 및 방법
CN111670197A (zh) * 2017-12-05 2020-09-15 普莱戈斯瑞恩癌症有限责任公司 治疗癌症的抗前胃泌激素抗体与免疫疗法的组合疗法
JP7485274B2 (ja) * 2018-02-27 2024-05-16 イー、シー、エス、プロガストリン、エス、エー 免疫療法のためのバイオマーカーとしてのプロガストリン

Also Published As

Publication number Publication date
ES2920283T3 (es) 2022-08-02
CA3084687C (en) 2024-01-02
CN111670197A (zh) 2020-09-15
CA3084687A1 (en) 2019-06-13
WO2019110662A1 (en) 2019-06-13
JP2021505576A (ja) 2021-02-18
TWI763956B (zh) 2022-05-11
AU2018379320B2 (en) 2023-06-15
EP3720879B1 (en) 2022-05-11
PL3720879T3 (pl) 2022-09-12
US20210324069A1 (en) 2021-10-21
AU2018379320A1 (en) 2020-07-02
US11046758B2 (en) 2021-06-29
KR102461238B1 (ko) 2022-11-01
RU2020121176A (ru) 2022-01-10
TW201927805A (zh) 2019-07-16
US20210009680A1 (en) 2021-01-14
EP3720879A1 (en) 2020-10-14
KR20200118409A (ko) 2020-10-15
JP7104153B2 (ja) 2022-07-20
SG11202005296SA (en) 2020-07-29
RU2020121176A3 (pt) 2022-04-27
DK3720879T3 (da) 2022-06-20

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