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PT2540820T - Meios e métodos para influenciar a establidade de células produtoras de anticorpos - Google Patents

Meios e métodos para influenciar a establidade de células produtoras de anticorpos

Info

Publication number
PT2540820T
PT2540820T PT121751986T PT12175198T PT2540820T PT 2540820 T PT2540820 T PT 2540820T PT 121751986 T PT121751986 T PT 121751986T PT 12175198 T PT12175198 T PT 12175198T PT 2540820 T PT2540820 T PT 2540820T
Authority
PT
Portugal
Prior art keywords
influencing
stability
methods
producing cells
antibody producing
Prior art date
Application number
PT121751986T
Other languages
English (en)
Inventor
Beaumont Tim
Spits Hergen
Alexander Scheeren Ferenc
Andrew Diehl Sean
Original Assignee
Academisch Medisch Centrum Bij De Univ Van Amsterdam
Aimm Therapeutics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37714656&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2540820(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/NL2005/000848 external-priority patent/WO2007067032A1/en
Application filed by Academisch Medisch Centrum Bij De Univ Van Amsterdam, Aimm Therapeutics Bv filed Critical Academisch Medisch Centrum Bij De Univ Van Amsterdam
Publication of PT2540820T publication Critical patent/PT2540820T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0635—B lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/231—Interleukin-10 (IL-10)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2321—Interleukin-21 (IL-21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/52—CD40, CD40-ligand (CD154)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT121751986T 2005-12-09 2006-12-08 Meios e métodos para influenciar a establidade de células produtoras de anticorpos PT2540820T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/NL2005/000848 WO2007067032A1 (en) 2005-12-09 2005-12-09 Means and methods for influencing the stability of cells
EP06076211 2006-06-12

Publications (1)

Publication Number Publication Date
PT2540820T true PT2540820T (pt) 2018-03-02

Family

ID=37714656

Family Applications (2)

Application Number Title Priority Date Filing Date
PT121751986T PT2540820T (pt) 2005-12-09 2006-12-08 Meios e métodos para influenciar a establidade de células produtoras de anticorpos
PT06824300T PT1974017E (pt) 2005-12-09 2006-12-08 Meios e métodos para influenciar a estabilidade de células produtoras de anticorpo

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT06824300T PT1974017E (pt) 2005-12-09 2006-12-08 Meios e métodos para influenciar a estabilidade de células produtoras de anticorpo

Country Status (14)

Country Link
US (3) US9127251B2 (pt)
EP (3) EP2540820B1 (pt)
JP (2) JP5753339B2 (pt)
AU (2) AU2006323315B2 (pt)
BR (2) BR122021001906B1 (pt)
CA (2) CA3015416C (pt)
DK (2) DK2540820T3 (pt)
ES (2) ES2444465T5 (pt)
FI (1) FI1974017T4 (pt)
HU (1) HUE037580T2 (pt)
NZ (3) NZ569543A (pt)
PL (2) PL1974017T5 (pt)
PT (2) PT2540820T (pt)
WO (1) WO2007067046A1 (pt)

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WO2007067032A1 (en) 2005-12-09 2007-06-14 Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of cells
BR122021001906B1 (pt) 2005-12-09 2022-03-29 Kling Biotherapeutics B.V. Método para aumentar a estabilidade de uma célula produtora de anticorpo, método para produzir uma célula produtora de anticorpo que é estável durante pelo menos uma semana, método para produzir linhagem de células b, e método ex vivo para produzir anticorpos capazes de especificamente ligar um antígeno de interesse
EP1997830A1 (en) * 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
JP5205597B2 (ja) * 2007-06-01 2013-06-05 静岡県 １細胞レベルでの抗体遺伝子の解析・同定方法
US8715743B2 (en) 2007-08-03 2014-05-06 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
WO2010003529A1 (en) * 2008-06-16 2010-01-14 University Of Zurich Method of providing immunoglobulin secreting b lymphocytes and human antibodies
CA2761648C (en) 2009-05-11 2019-03-12 Crucell Holland B.V. Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
DK2454283T3 (en) 2009-07-15 2018-05-07 Aimm Therapeutics Bv METHODS AND PROCEDURES FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
EP3037435B1 (en) 2009-11-17 2019-08-07 MUSC Foundation for Research Development Human monoclonal antibodies to human nucleolin
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CA2819070C (en) 2010-12-02 2020-03-10 Aimm Therapeutics B.V. Means and methods for producing high affinity antibodies
WO2013081463A2 (en) 2011-12-02 2013-06-06 Aimm Therapeutics B.V. Influenza a virus specific antibodies
US10017739B2 (en) 2012-09-06 2018-07-10 Duke University Methods of expanding and assessing B cells and using expanded B cells to treat disease
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CA2934660C (en) 2013-12-24 2023-03-14 Aimm Therapeutics B.V. Ex vivo antibody production
CA2938193C (en) 2014-01-31 2023-05-02 Aimm Therapeutics B.V. Means and methods for producing stable antibodies
EP3152569B1 (en) * 2014-06-05 2020-06-10 AIMM Therapeutics B.V. Means and methods for determining t cell recognition
US10428304B2 (en) 2014-07-02 2019-10-01 Tokyo University Of Science Foundation Method for producing B cell population
EP3234107B1 (en) * 2014-12-19 2022-09-14 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
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EP3400245A1 (en) 2016-01-08 2018-11-14 Aimm Therapeutics B.V. Therapeutic anti-cd9 antibody
AU2017367695A1 (en) 2016-12-02 2019-06-13 Juno Therapeutics, Inc. Engineered B cells and related compositions and methods
US10908168B2 (en) 2017-01-31 2021-02-02 Vanderbilt University Generation of human allergen- and helminth-specific IgE monoclonal antibodies for diagnostic and therapeutic use
US11125757B2 (en) 2017-05-26 2021-09-21 Emory University Methods of culturing and characterizing antibody secreting cells
CN111683964A (zh) * 2017-12-05 2020-09-18 Sqz生物技术公司 细胞内递送生物分子来调节抗体产生

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WO2013081463A2 (en) 2011-12-02 2013-06-06 Aimm Therapeutics B.V. Influenza a virus specific antibodies

Also Published As

Publication number Publication date
EP1974017B2 (en) 2023-06-21
EP3327117A1 (en) 2018-05-30
US20100113745A1 (en) 2010-05-06
US9822339B2 (en) 2017-11-21
EP2540820B1 (en) 2018-01-10
JP2013099358A (ja) 2013-05-23
NZ600075A (en) 2013-12-20
ES2660899T3 (es) 2018-03-26
US9127251B2 (en) 2015-09-08
PT1974017E (pt) 2014-02-11
AU2006323315B2 (en) 2014-02-20
DK1974017T4 (da) 2023-09-25
PL2540820T3 (pl) 2018-05-30
BRPI0619579B1 (pt) 2021-07-20
WO2007067046A1 (en) 2007-06-14
US20160060598A1 (en) 2016-03-03
PL1974017T5 (pl) 2023-10-23
NZ592159A (en) 2012-12-21
ES2444465T3 (es) 2014-02-25
ES2444465T5 (es) 2023-11-30
JP5753339B2 (ja) 2015-07-22
CA2633157A1 (en) 2007-06-14
CA2633157C (en) 2018-10-09
EP2540820A1 (en) 2013-01-02
US10273454B2 (en) 2019-04-30
FI1974017T4 (fi) 2023-09-14
HUE037580T2 (hu) 2018-09-28
NZ569543A (en) 2012-12-21
DK1974017T3 (da) 2014-02-10
BR122021001906B1 (pt) 2022-03-29
AU2014202709A1 (en) 2014-06-12
BRPI0619579A2 (pt) 2011-10-04
CA3015416A1 (en) 2007-06-14
US20170306293A1 (en) 2017-10-26
DK2540820T3 (en) 2018-03-12
EP1974017B1 (en) 2013-11-06
JP2009518033A (ja) 2009-05-07
PL1974017T3 (pl) 2014-04-30
CA3015416C (en) 2022-10-11
BRPI0619579B8 (pt) 2022-01-25
AU2006323315A1 (en) 2007-06-14
AU2014202709B2 (en) 2016-09-08
JP5753547B2 (ja) 2015-07-22
EP1974017A1 (en) 2008-10-01

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