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PL406149A1 - Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications - Google Patents

Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications

Info

Publication number
PL406149A1
PL406149A1 PL406149A PL40614913A PL406149A1 PL 406149 A1 PL406149 A1 PL 406149A1 PL 406149 A PL406149 A PL 406149A PL 40614913 A PL40614913 A PL 40614913A PL 406149 A1 PL406149 A1 PL 406149A1
Authority
PL
Poland
Prior art keywords
compounds
derivatives
dimethyl
amino
triazoles
Prior art date
Application number
PL406149A
Other languages
Polish (pl)
Inventor
Leszek Ciunik
Damian Pieniążczak
Bogumiła Szponar
Katarzyna Wajda-Hermanowicz
Aleksandra Zatajska
Original Assignee
Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością filed Critical Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością
Priority to PL406149A priority Critical patent/PL406149A1/en
Priority to PCT/PL2014/000132 priority patent/WO2015076684A1/en
Publication of PL406149A1 publication Critical patent/PL406149A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem wynalazku są nowe pochodne 4-amino-3,5-dimetylo-4H-1,2,4-triazoli, sposób ich otrzymywania, środek farmaceutyczny zawierający nowe związki oraz ich zastosowanie. Są to związki powstałe w wyniku reakcji 4-amino-3,5-dimetylo-4H-l,2,4-triazolu z pochodnymi benzaldehydów. Związki te charakteryzują się centrami chiralności i wynikającymi z nich właściwościami chemicznymi i biologicznymi. Nowe pochodne triazolu znajdują zastosowanie jako substancje aktywne stosowanych w profilaktyce i leczeniu infekcji wywołanych obecnością grzybów lub bakterii.The subject of the invention are new 4-amino-3,5-dimethyl-4H-1,2,4-triazoles derivatives, their preparation, pharmaceutical agent containing new compounds and their use. These are compounds resulting from the reaction of 4-amino-3,5-dimethyl-4H-1,2,4-triazole with benzaldehyde derivatives. These compounds are characterized by centers of chirality and the resulting chemical and biological properties. New triazole derivatives are used as active substances used in the prevention and treatment of infections caused by the presence of fungi or bacteria.

PL406149A 2013-11-20 2013-11-20 Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications PL406149A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL406149A PL406149A1 (en) 2013-11-20 2013-11-20 Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications
PCT/PL2014/000132 WO2015076684A1 (en) 2013-11-20 2014-11-18 4-amino-3,5-dimethyl-4h-1,2,4-triazole derivatives, method of preparation thereof, a pharmaceutical compound containing the same and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL406149A PL406149A1 (en) 2013-11-20 2013-11-20 Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications

Publications (1)

Publication Number Publication Date
PL406149A1 true PL406149A1 (en) 2015-05-25

Family

ID=52232378

Family Applications (1)

Application Number Title Priority Date Filing Date
PL406149A PL406149A1 (en) 2013-11-20 2013-11-20 Derivatives of 4-amino-3, 5-dimethyl-4H-1, 2,4-triazoles, method for obtaining them, pharmaceutical containing these compounds and their applications

Country Status (2)

Country Link
PL (1) PL406149A1 (en)
WO (1) WO2015076684A1 (en)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147791A (en) 1972-01-11 1979-04-03 Bayer Aktiengesellschaft 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants
US4048318A (en) 1972-01-11 1977-09-13 Bayer Aktiengesellschaft 1-Substituted-1,2,4-triazole fungicides
US4038406A (en) 1972-09-26 1977-07-26 Bayer Aktiengesellschaft 1,2,4-triazole antimycotic compositions and use thereof
DE2552967A1 (en) 1975-11-26 1977-06-08 Bayer Ag FUNGICIDALS
PL120261B1 (en) 1979-03-20 1982-02-27 Polska Akademia Nauk Instytut Method of manufacture of the element from copper alloy exhibiting effect of elastic memoryhhego ehffektom pamjati formy
US6914058B2 (en) 2002-01-18 2005-07-05 Dr. Reddy's Laboratories, Limited Antibacterial compounds: process for their preparation and pharmaceutical compositions containing them
MY130685A (en) 2002-02-05 2007-07-31 Janssen Pharmaceutica Nv Formulations comprising triazoles and alkoxylated amines
US20060270628A1 (en) 2003-04-29 2006-11-30 Jagattaran Das Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them
JP5055263B2 (en) 2005-03-30 2012-10-24 ダエウン ファーマシューティカル カンパニー リミテッド Antifungal triazole derivatives
PL214249B1 (en) * 2007-06-29 2013-07-31 Inst Immunologii I Terapii Doswiadczalnej Polska Akademia Nauk New derivatives of triazoles, the manner of obtaining them and their application

Also Published As

Publication number Publication date
WO2015076684A1 (en) 2015-05-28

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