PL380414A1 - 4-Diarylo-1- fenyloazetydyn-2-ony - Google Patents

4-Diarylo-1- fenyloazetydyn-2-ony

Info

Publication number: PL380414A1
Authority: PL; Poland
Prior art keywords: biarylyl; phenylazetidin; img; ones; tif
Prior art date: 2003-11-10

Application number

PL380414A

Other languages

English (en)

Inventor

Eduardo Martinez

John J. Talley

Stephen Antonelli

Timothy C. Barden

Regina Lundrigan-Soucy

Wayne C. Schairer

Jing-Jing Yang

Daniel P. Zimmer

Mark G. Currie

Peter S. Yorgey

Brian Cali

Original Assignee

Microbia, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-10

Filing date

2004-11-10

Publication date

2007-01-22

2004-11-10 Application filed by Microbia, Inc. filed Critical Microbia, Inc.

2007-01-22 Publication of PL380414A1 publication Critical patent/PL380414A1/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL380414A 2003-11-10 2004-11-10 4-Diarylo-1- fenyloazetydyn-2-ony PL380414A1 (pl)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US51869803P	2003-11-10	2003-11-10
US54957704P	2004-03-03	2004-03-03
US59252904P	2004-07-30	2004-07-30
US61400504P	2004-09-28	2004-09-28
PCT/US2004/037715 WO2005047248A1 (en)	2003-11-10	2004-11-10	4-biarylyl-1-phenylazetidin-2-ones

Publications (1)

Publication Number	Publication Date
PL380414A1 true PL380414A1 (pl)	2007-01-22

Family

ID=34596124

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL380414A PL380414A1 (pl)	2003-11-10	2004-11-10	4-Diarylo-1- fenyloazetydyn-2-ony
PL04810780T PL1682499T3 (pl)	2003-11-10	2004-11-10	4-Biarylilo-1-fenyloazetydyn-2-ony

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL04810780T PL1682499T3 (pl)	2003-11-10	2004-11-10	4-Biarylilo-1-fenyloazetydyn-2-ony

Country Status (22)

Country	Link
US (2)	US7320972B2 (pl)
EP (1)	EP1682499B1 (pl)
JP (1)	JP2007520453A (pl)
KR (1)	KR20070050861A (pl)
AT (1)	ATE369335T1 (pl)
AU (1)	AU2004288822A1 (pl)
BR (1)	BRPI0416361A (pl)
CA (1)	CA2545058A1 (pl)
CY (1)	CY1106982T1 (pl)
DE (1)	DE602004008100T2 (pl)
DK (1)	DK1682499T3 (pl)
EA (1)	EA010026B1 (pl)
ES (1)	ES2291974T3 (pl)
HK (1)	HK1093974A1 (pl)
IL (1)	IL175414A0 (pl)
MA (1)	MA28216A1 (pl)
MX (1)	MXPA06005106A (pl)
NO (1)	NO20062665L (pl)
NZ (1)	NZ546940A (pl)
PL (2)	PL380414A1 (pl)
PT (1)	PT1682499E (pl)
WO (1)	WO2005047248A1 (pl)

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PL380414A1 (pl) *	2003-11-10	2007-01-22	Microbia, Inc.	4-Diarylo-1- fenyloazetydyn-2-ony
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2004
- 2004-11-10 PL PL380414A patent/PL380414A1/pl not_active Application Discontinuation
- 2004-11-10 BR BRPI0416361-3A patent/BRPI0416361A/pt not_active IP Right Cessation
- 2004-11-10 CA CA002545058A patent/CA2545058A1/en not_active Abandoned
- 2004-11-10 PL PL04810780T patent/PL1682499T3/pl unknown
- 2004-11-10 PT PT04810780T patent/PT1682499E/pt unknown
- 2004-11-10 US US10/986,570 patent/US7320972B2/en not_active Expired - Fee Related
- 2004-11-10 EP EP04810780A patent/EP1682499B1/en not_active Expired - Lifetime
- 2004-11-10 ES ES04810780T patent/ES2291974T3/es not_active Expired - Lifetime
- 2004-11-10 KR KR1020067011344A patent/KR20070050861A/ko not_active Application Discontinuation
- 2004-11-10 WO PCT/US2004/037715 patent/WO2005047248A1/en active IP Right Grant
- 2004-11-10 AU AU2004288822A patent/AU2004288822A1/en not_active Abandoned
- 2004-11-10 EA EA200600950A patent/EA010026B1/ru not_active IP Right Cessation
- 2004-11-10 JP JP2006539874A patent/JP2007520453A/ja active Pending
- 2004-11-10 NZ NZ546940A patent/NZ546940A/en unknown
- 2004-11-10 AT AT04810780T patent/ATE369335T1/de not_active IP Right Cessation
- 2004-11-10 DE DE602004008100T patent/DE602004008100T2/de not_active Expired - Lifetime
- 2004-11-10 MX MXPA06005106A patent/MXPA06005106A/es active IP Right Grant
- 2004-11-10 DK DK04810780T patent/DK1682499T3/da active
2006
- 2006-05-04 IL IL175414A patent/IL175414A0/en unknown
- 2006-05-05 MA MA29006A patent/MA28216A1/fr unknown
- 2006-06-09 NO NO20062665A patent/NO20062665L/no not_active Application Discontinuation
- 2006-12-22 HK HK06114125A patent/HK1093974A1/xx not_active IP Right Cessation
2007
- 2007-11-08 CY CY20071101429T patent/CY1106982T1/el unknown
- 2007-12-11 US US11/954,170 patent/US20080167255A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PL1682499T3 (pl)	2008-01-31
ATE369335T1 (de)	2007-08-15
MA28216A1 (fr)	2006-10-02
NZ546940A (en)	2008-11-28
US20050209165A1 (en)	2005-09-22
US20080167255A1 (en)	2008-07-10
EA200600950A1 (ru)	2006-10-27
EP1682499A1 (en)	2006-07-26
DE602004008100D1 (de)	2007-09-20
EP1682499B1 (en)	2007-08-08
IL175414A0 (en)	2006-09-05
DE602004008100T2 (de)	2008-04-30
ES2291974T3 (es)	2008-03-01
HK1093974A1 (en)	2007-03-16
MXPA06005106A (es)	2007-01-25
US7320972B2 (en)	2008-01-22
JP2007520453A (ja)	2007-07-26
DK1682499T3 (da)	2008-01-02
CY1106982T1 (el)	2012-09-26
BRPI0416361A (pt)	2007-05-08
WO2005047248A1 (en)	2005-05-26
PT1682499E (pt)	2007-11-05
AU2004288822A1 (en)	2005-05-26
KR20070050861A (ko)	2007-05-16
NO20062665L (no)	2006-08-09
EA010026B1 (ru)	2008-06-30
CA2545058A1 (en)	2005-05-26

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ZA200405322B (en)	2005-07-27	Process for the manufacture of hmg-coa reductase inhibitors
EP1604980A8 (en)	2006-03-15	DPP-IV inhibitors
ATE482933T1 (de)	2010-10-15	Sulfopyrrolderivate
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SI1377574T1 (pl)	2005-08-31
WO2005025492A3 (en)	2005-08-11	Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease
ATE301655T1 (de)	2005-08-15	Triazatrinaphthyrinen und ihre verwendung
RS20050181A (en)	2007-06-04	Novel benzonaphthyridines
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2013-12-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)