PL310386A1 - Antagonists of factor i receptors - Google Patents

Antagonists of factor i receptors

Info

Publication number: PL310386A1
Authority: PL; Poland
Prior art keywords: antagonists; receptors; factor
Prior art date: 1993-02-22

Application number

PL94310386A

Inventor

David Alan Claremon

John J Baldwin

Nigel Liverton

Ben Askew

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-22

Filing date

1994-02-22

Publication date

1995-12-11

1994-02-22 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1995-12-11 Publication of PL310386A1 publication Critical patent/PL310386A1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)

PL94310386A 1993-02-22 1994-02-22 Antagonists of factor i receptors PL310386A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2051793A	1993-02-22	1993-02-22
PCT/US1994/001881 WO1994018981A1 (en)	1993-02-22	1994-02-22	Fibrinogen receptor antagonists

Publications (1)

Publication Number	Publication Date
PL310386A1 true PL310386A1 (en)	1995-12-11

Family

ID=21799049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL94310386A PL310386A1 (en)	1993-02-22	1994-02-22	Antagonists of factor i receptors

Country Status (15)

Country	Link
EP (1)	EP0684823A4 (en)
JP (1)	JP3173792B2 (en)
KR (1)	KR960700722A (en)
CN (1)	CN1118139A (en)
AU (1)	AU680240B2 (en)
BG (1)	BG99863A (en)
CA (1)	CA2155123A1 (en)
CZ (1)	CZ210895A3 (en)
FI (1)	FI953916A (en)
HU (1)	HUT71796A (en)
NO (1)	NO953270L (en)
NZ (1)	NZ262664A (en)
PL (1)	PL310386A1 (en)
SK (1)	SK102495A3 (en)
WO (1)	WO1994018981A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5849736A (en) *	1993-11-24	1998-12-15	The Dupont Merck Pharmaceutical Company	Isoxazoline and isoxazole fibrinogen receptor antagonists
US5494921A (en) *	1994-09-16	1996-02-27	Merck & Co., Inc.	Fibrinogen receptor antagonists
ZA963391B (en) *	1995-05-24	1997-10-29	Du Pont Merck Pharma	Isoxazoline fibrinogen receptor antagonists.
US6100423A (en) *	1995-08-30	2000-08-08	G. D. Searle & Co.	Amino benzenepropanoic acid compounds and derivatives thereof
AU702487B2 (en)	1995-08-30	1999-02-25	G.D. Searle & Co.	Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists
ES2227612T3 (en)	1995-09-29	2005-04-01	Eli Lilly And Company	ESPIRO COMPOUNDS AS FIBRINOGEN DEPENDENT PLAQUETARY AGGREGATION INHIBITORS.
CA2240439A1 (en) *	1995-12-22	1997-07-03	The Dupont Merck Pharmaceutical Company	Novel integrin receptor antagonists
AU2340997A (en) *	1996-03-27	1997-10-17	Merck & Co., Inc.	A method for inhibiting clot formation
WO1998004247A1 (en) *	1996-07-25	1998-02-05	Biogen, Inc.	Cell adhesion inhibitors
US5900414A (en) *	1996-08-29	1999-05-04	Merck & Co., Inc.	Methods for administering integrin receptor antagonists
DE19653647A1 (en) *	1996-12-20	1998-06-25	Hoechst Ag	Vitronectin receptor antagonists, their preparation and their use
WO1998034935A1 (en) *	1997-02-06	1998-08-13	Merck & Co., Inc.	Fibrinogen receptor antagonist prodrugs
WO1998043962A1 (en) *	1997-03-28	1998-10-08	Du Pont Pharmaceuticals Company	Heterocyclic integrin inhibitor prodrugs
US6303625B1 (en) *	1998-07-27	2001-10-16	Ortho-Mcneil Pharmaceutical, Inc.	Triazolopyridines for the treatment of thrombosis disorders
RU2002105011A (en) *	1999-07-28	2004-01-20	Авентис Фармасьютикалз Инк. (Us)	Substituted oxoazheterocyclic derivatives
CA2509565A1 (en) *	2002-12-20	2004-07-15	Pharmacia Corporation	Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds
US20100035756A1 (en) *	2006-07-12	2010-02-11	Syngenta Limited	Triazolophyridine derivatives as herbicides
CA2719288A1 (en) *	2008-04-04	2009-11-12	Gilead Sciences, Inc.	Triazolopyridinone derivatives for use as stearoyl coa desaturase inhibitors
WO2010096722A1 (en) *	2009-02-20	2010-08-26	Takeda Pharmaceutical Company Limited	3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5084466A (en) *	1989-01-31	1992-01-28	Hoffmann-La Roche Inc.	Novel carboxamide pyridine compounds which have useful pharmaceutical utility
GB8913011D0 (en) *	1989-06-06	1989-07-26	Wellcome Found	Anticonvulsant pyrazines
US5166154A (en) *	1989-10-17	1992-11-24	Boehringer Ingelheim Pharmaceuticals, Inc.	Imidazo[1,2-a]piperazines
US5278161A (en) *	1990-06-28	1994-01-11	Hoffmann-La Roche Inc.	Amino acid derivatives useful as renin inhibitors

1994
- 1994-02-22 JP JP51922094A patent/JP3173792B2/en not_active Expired - Fee Related
- 1994-02-22 EP EP94909745A patent/EP0684823A4/en not_active Withdrawn
- 1994-02-22 AU AU62465/94A patent/AU680240B2/en not_active Ceased
- 1994-02-22 PL PL94310386A patent/PL310386A1/en unknown
- 1994-02-22 NZ NZ262664A patent/NZ262664A/en unknown
- 1994-02-22 CN CN94191248A patent/CN1118139A/en active Pending
- 1994-02-22 HU HU9502028A patent/HUT71796A/en unknown
- 1994-02-22 CA CA002155123A patent/CA2155123A1/en not_active Abandoned
- 1994-02-22 WO PCT/US1994/001881 patent/WO1994018981A1/en not_active Application Discontinuation
- 1994-02-22 SK SK1024-95A patent/SK102495A3/en unknown
- 1994-02-22 CZ CZ952108A patent/CZ210895A3/en unknown
1995
- 1995-08-15 BG BG99863A patent/BG99863A/en unknown
- 1995-08-21 KR KR1019950703563A patent/KR960700722A/en not_active Application Discontinuation
- 1995-08-21 NO NO953270A patent/NO953270L/en unknown
- 1995-08-21 FI FI953916A patent/FI953916A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI953916A0 (en)	1995-08-21
JPH08507072A (en)	1996-07-30
NZ262664A (en)	1997-04-24
HU9502028D0 (en)	1995-09-28
NO953270L (en)	1995-10-19
NO953270D0 (en)	1995-08-21
CN1118139A (en)	1996-03-06
JP3173792B2 (en)	2001-06-04
FI953916A (en)	1995-08-21
CA2155123A1 (en)	1994-09-01
AU6246594A (en)	1994-09-14
EP0684823A1 (en)	1995-12-06
HUT71796A (en)	1996-02-28
SK102495A3 (en)	1997-01-08
AU680240B2 (en)	1997-07-24
CZ210895A3 (en)	1996-02-14
WO1994018981A1 (en)	1994-09-01
BG99863A (en)	1996-02-29
KR960700722A (en)	1996-02-24
EP0684823A4 (en)	1997-07-09

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PL330850A1 (en)	1999-06-07	Antagonists of il-8 receptors
PL330849A1 (en)	1999-06-07	Antagonists of il-8 receptors
AU3665793A (en)	1993-09-13	Fibrinogen receptor antagonists
GR3036881T3 (en)	2002-01-31	Benzamide derivatives and their use as vasopressin antagonists
PL310386A1 (en)	1995-12-11	Antagonists of factor i receptors
GB9405317D0 (en)	1994-04-27	Fibrinogen receptor antagonists
HU9301603D0 (en)	1993-09-28	Angiotensine 11 antagonists
HU9601529D0 (en)	1996-07-29	Pyrimidinedion-, pyrimidinetrion-, triazinedion-, tetrahydro-quinazolinedion- derivatives as alpha-adrenerg receptor antagonists
IL115613A0 (en)	1996-01-19	Bicyclic neuropeptide y receptor antagonists
EP0810994A4 (en)	1998-05-06	Fibrinogen receptor antagonists
EP0866705A4 (en)	1999-03-03	Fibrinogen receptor antagonists
PL334499A1 (en)	2000-02-28	Antagonists of vitronectin receptors
PL341114A1 (en)	2001-03-26	Antagonists of thrombosin receptors
EP0796098A4 (en)	1998-04-29	Fibrinogen receptor antagonists
IL113050A0 (en)	1995-06-29	Antagonists of endothelin receptors
EP0801650A4 (en)	1998-05-06	Fibrinogen receptor antagonists
PL328633A1 (en)	1999-02-15	Oxazolic and thiadizolic antagonists of muscarinic receptors
GB9217475D0 (en)	1992-09-30	Nauroprotective use cck antagonists
AU5322994A (en)	1994-05-09	Fibrinogen receptor antagonists
HU9503191D0 (en)	1996-01-29	Adhesion-receptor antagonists