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PL2558854T3 - Biomarkery będące krążącymi kwasami nukleinowymi związanymi z rakiem piersi - Google Patents

Biomarkery będące krążącymi kwasami nukleinowymi związanymi z rakiem piersi

Info

Publication number
PL2558854T3
PL2558854T3 PL11769758T PL11769758T PL2558854T3 PL 2558854 T3 PL2558854 T3 PL 2558854T3 PL 11769758 T PL11769758 T PL 11769758T PL 11769758 T PL11769758 T PL 11769758T PL 2558854 T3 PL2558854 T3 PL 2558854T3
Authority
PL
Poland
Prior art keywords
nucleic acid
breast cancer
cancer associated
circulating nucleic
acid biomarkers
Prior art date
Application number
PL11769758T
Other languages
English (en)
Inventor
Ekkehard Schütz
Julia Beck
Howard Urnovitz
Original Assignee
Chronix Biomedical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chronix Biomedical filed Critical Chronix Biomedical
Publication of PL2558854T3 publication Critical patent/PL2558854T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL11769758T 2010-04-16 2011-04-18 Biomarkery będące krążącymi kwasami nukleinowymi związanymi z rakiem piersi PL2558854T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32492710P 2010-04-16 2010-04-16
EP11769758.1A EP2558854B1 (en) 2010-04-16 2011-04-18 Breast cancer associated circulating nucleic acid biomarkers
PCT/US2011/032931 WO2011130751A1 (en) 2010-04-16 2011-04-18 Breast cancer associated circulating nucleic acid biomarkers

Publications (1)

Publication Number Publication Date
PL2558854T3 true PL2558854T3 (pl) 2019-04-30

Family

ID=44799071

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11769758T PL2558854T3 (pl) 2010-04-16 2011-04-18 Biomarkery będące krążącymi kwasami nukleinowymi związanymi z rakiem piersi

Country Status (6)

Country Link
US (3) US10047397B2 (pl)
EP (1) EP2558854B1 (pl)
CA (1) CA2796578C (pl)
ES (1) ES2703769T3 (pl)
PL (1) PL2558854T3 (pl)
WO (1) WO2011130751A1 (pl)

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US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US10179937B2 (en) 2014-04-21 2019-01-15 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
KR102040307B1 (ko) * 2010-11-30 2019-11-27 더 차이니즈 유니버시티 오브 홍콩 암과 연관된 유전적 또는 분자적 이상들의 검출
US9260753B2 (en) 2011-03-24 2016-02-16 President And Fellows Of Harvard College Single cell nucleic acid detection and analysis
WO2013066641A1 (en) * 2011-10-21 2013-05-10 Chronix Biomedical Colorectal cancer associated circulating nucleic acid biomarkers
US10214775B2 (en) 2011-12-07 2019-02-26 Chronix Biomedical Prostate cancer associated circulating nucleic acid biomarkers
CN104685064A (zh) * 2012-07-24 2015-06-03 纳特拉公司 高度复合pcr方法和组合物
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
ES2906714T3 (es) 2012-09-04 2022-04-20 Guardant Health Inc Métodos para detectar mutaciones raras y variación en el número de copias
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
US9732390B2 (en) 2012-09-20 2017-08-15 The Chinese University Of Hong Kong Non-invasive determination of methylome of fetus or tumor from plasma
US10706957B2 (en) 2012-09-20 2020-07-07 The Chinese University Of Hong Kong Non-invasive determination of methylome of tumor from plasma
JP6571665B2 (ja) 2013-12-28 2019-09-04 ガーダント ヘルス, インコーポレイテッド 遺伝的バリアントを検出するための方法およびシステム
EP3543356B1 (en) 2014-07-18 2021-06-30 The Chinese University of Hong Kong Methylation pattern analysis of tissues in dna mixture
DK3294906T3 (en) 2015-05-11 2024-08-05 Natera Inc Methods for determining ploidy
CN117174167A (zh) 2015-12-17 2023-12-05 夸登特健康公司 通过分析无细胞dna确定肿瘤基因拷贝数的方法
CN109477138A (zh) 2016-04-15 2019-03-15 纳特拉公司 肺癌检测方法
SG11201810544WA (en) 2016-05-30 2018-12-28 Univ Hong Kong Chinese Detecting hematological disorders using cell-free dna in blood
TWI797095B (zh) 2016-10-24 2023-04-01 美商格瑞爾有限責任公司 腫瘤檢測之方法及系統
IL315032A (en) 2016-11-30 2024-10-01 Univ Hong Kong Chinese Analysis of cell-free dna in urine and other samples
US10633713B2 (en) 2017-01-25 2020-04-28 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments
JP2020527958A (ja) 2017-07-26 2020-09-17 ザ チャイニーズ ユニバーシティー オブ ホンコンThe Chinese University Of Hongkong 無細胞ウイルス核酸を用いる癌スクリーニングの強化
WO2019118926A1 (en) 2017-12-14 2019-06-20 Tai Diagnostics, Inc. Assessing graft suitability for transplantation
CA3092998A1 (en) 2018-03-13 2019-09-19 Grail, Inc. Anomalous fragment detection and classification
AU2019251504A1 (en) 2018-04-14 2020-08-13 Natera, Inc. Methods for cancer detection and monitoring by means of personalized detection of circulating tumor DNA
WO2020132572A1 (en) 2018-12-21 2020-06-25 Grail, Inc. Source of origin deconvolution based on methylation fragments in cell-free-dna samples
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
CN114107510B (zh) * 2021-12-10 2023-10-03 湖南工程学院 基于dna三链介导构建多维dna酶矩阵的超灵敏循环核酸检测体系、试剂盒和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100776214B1 (ko) * 2004-08-23 2008-01-17 주식회사 마크로젠 염색체 이상 검정방법 및 마이크로어레이 칩
WO2007061876A2 (en) 2005-11-23 2007-05-31 University Of Utah Research Foundation Methods and compositions involving intrinsic genes
EP2092322B1 (en) 2006-12-14 2016-02-17 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale fet arrays
US12180549B2 (en) 2007-07-23 2024-12-31 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using genomic sequencing
US8682597B2 (en) 2007-10-16 2014-03-25 Exxonmobil Research And Engineering Company Estimating detailed compositional information from limited analytical data
WO2009051842A2 (en) * 2007-10-18 2009-04-23 The Johns Hopkins University Detection of cancer by measuring genomic copy number and strand length in cell-free dna
US20100035252A1 (en) 2008-08-08 2010-02-11 Ion Torrent Systems Incorporated Methods for sequencing individual nucleic acids under tension

Also Published As

Publication number Publication date
US20220333213A1 (en) 2022-10-20
EP2558854A4 (en) 2014-03-05
EP2558854A1 (en) 2013-02-20
CA2796578C (en) 2021-11-23
ES2703769T3 (es) 2019-03-12
EP2558854B1 (en) 2018-10-10
US11377695B2 (en) 2022-07-05
US20130116127A1 (en) 2013-05-09
US20190078165A1 (en) 2019-03-14
WO2011130751A1 (en) 2011-10-20
US10047397B2 (en) 2018-08-14
CA2796578A1 (en) 2011-10-20

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