PL1756086T3 - Pirydyn-4-ylo-etynylo-imidazole i pirazole jako antagoniści receptora mGlu5 - Google Patents

Pirydyn-4-ylo-etynylo-imidazole i pirazole jako antagoniści receptora mGlu5

Info

Publication number: PL1756086T3
Authority: PL; Poland
Prior art keywords: pyrazoles; imidazoles; ethynyl; pyridin; receptor antagonists
Prior art date: 2004-06-01

Application number

PL05744719T

Other languages

English (en)

Inventor

Bernd Buettelmann

Simona Maria Ceccarelli

Georg Jaeschke

Sabine Kolczewski

Richard Hugh Philip Porter

Eric Vieira

Paul Spurr

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-01

Filing date

2005-05-23

Publication date

2008-11-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34968402&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1756086(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-06-01 Priority claimed from PCT/EP2004/005881 external-priority patent/WO2004108701A1/en

2005-05-23 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2008-11-28 Publication of PL1756086T3 publication Critical patent/PL1756086T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL05744719T 2004-06-01 2005-05-23 Pirydyn-4-ylo-etynylo-imidazole i pirazole jako antagoniści receptora mGlu5 PL1756086T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
PCT/EP2004/005881 WO2004108701A1 (en)	2003-06-05	2004-06-01	Imidazole derivatives as glutmate receptor antagonists
EP04021216		2004-09-07
EP05744719A EP1756086B1 (en)	2004-06-01	2005-05-23	Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as mglu5 receptor antagonists
PCT/EP2005/005559 WO2005118568A1 (en)	2004-06-01	2005-05-23	Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as mglu5 receptor antagonists

Publications (1)

Publication Number	Publication Date
PL1756086T3 true PL1756086T3 (pl)	2008-11-28

Family

ID=34968402

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL05744719T PL1756086T3 (pl)	2004-06-01	2005-05-23	Pirydyn-4-ylo-etynylo-imidazole i pirazole jako antagoniści receptora mGlu5

Country Status (10)

Country	Link
EP (1)	EP1756086B1 (pl)
CN (1)	CN1960984B (pl)
AT (1)	ATE397601T1 (pl)
AU (1)	AU2005250101B2 (pl)
CA (1)	CA2568725C (pl)
DE (1)	DE602005007350D1 (pl)
MX (1)	MXPA06013603A (pl)
PL (1)	PL1756086T3 (pl)
RS (1)	RS50603B (pl)
WO (1)	WO2005118568A1 (pl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102006011574A1 (de) *	2006-03-10	2007-10-31	Grünenthal GmbH	Substituierte Imidazo[2,1-b]thiazol-Verbindungen und ihre Verwendung zur Herstellung von Arzneimitteln
AU2007267183B2 (en)	2006-05-31	2011-10-20	F. Hoffmann-La Roche Ag	Aryl-4-ethynyl-isoxazole derivatives
JP5405311B2 (ja) *	2006-12-21	2014-02-05	エフ．ホフマン−ラロシュアーゲー	ｍＧｌｕＲ５受容体アンタゴニストの多形
CN101965344B (zh)	2007-06-22	2013-03-06	弗·哈夫曼-拉罗切有限公司	异*唑-咪唑衍生物
WO2009024491A1 (en) *	2007-08-20	2009-02-26	F. Hoffmann-La Roche Ag	Use of mglur5 antagonists for the treatment of gerd
US7618973B2 (en)	2007-12-04	2009-11-17	Hoffmann-La Roche Inc.	Isoxazolo-pyrazine derivatives
US7902201B2 (en)	2007-12-04	2011-03-08	Hoffmann-La Roche Inc.	Isoxazolo-pyrazine derivatives
US7943619B2 (en)	2007-12-04	2011-05-17	Hoffmann-La Roche Inc.	Isoxazolo-pyridazine derivatives
TW201033201A (en)	2009-02-19	2010-09-16	Hoffmann La Roche	Isoxazole-isoxazole and isoxazole-isothiazole derivatives
US8389550B2 (en)	2009-02-25	2013-03-05	Hoffmann-La Roche Inc.	Isoxazoles / O-pyridines with ethyl and ethenyl linker
US8222246B2 (en)	2009-04-02	2012-07-17	Hoffmann-La Roche Inc.	Substituted isoxazoles
US8227461B2 (en)	2009-04-30	2012-07-24	Hoffmann-La Roche Inc.	Isoxazoles
CA2760166C (en)	2009-05-05	2017-07-18	F. Hoffmann-La Roche Ag	Isoxazole-pyridine derivatives
BRPI1014454A2 (pt)	2009-05-05	2016-04-05	Hoffmann La Roche	derivados de isoxazol-pirazol
WO2010127968A1 (en)	2009-05-05	2010-11-11	F. Hoffmann-La Roche Ag	Isoxazole-pyridazine derivatives
CN102414208B (zh)	2009-05-05	2014-11-05	霍夫曼-拉罗奇有限公司	作为用于认知性障碍的治疗中的gaba a受体逆激动剂的异*唑-噻唑衍生物
AU2010244555A1 (en)	2009-05-07	2011-11-03	F. Hoffmann-La Roche Ag	Isoxazole-pyridine derivatives as GABA modulators
US8334287B2 (en) *	2009-07-17	2012-12-18	Hoffmann-La Roche Inc.	Imidazoles
US20120040008A1 (en) *	2010-08-11	2012-02-16	Ashish Chatterji	Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20120039999A1 (en) *	2010-08-11	2012-02-16	Ashish Chatterji	Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20140228398A1 (en)	2011-03-18	2014-08-14	Novartis Ag	COMBINATIONS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATORS AND mGluR5 ANTAGONISTS FOR USE IN DOPAMINE INDUCED DYSKINESIA IN PARKINSON'S DISEASE
US8785435B2 (en)	2011-10-20	2014-07-22	Hoffmann-La Roche Inc.	Solid forms
WO2013163402A1 (en) *	2012-04-26	2013-10-31	Massachusetts Institute Of Technology	Methods for treatment of 16p11.2 microdeletion syndrome
UA113223C2 (xx) *	2012-08-13	2016-12-26		Арилетинілпіримідини

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2383524C (en) *	1999-08-31	2010-09-28	Merck & Co., Inc.	Thiazolyl alkynyl compounds and methods of use thereof
KR100515549B1 (ko) *	2000-12-04	2005-09-20	에프. 호프만-라 로슈 아게	글루타메이트 수용체 길항제로서의 페닐에테닐 또는페닐에티닐 유도체
TWI292318B (en) *	2003-03-10	2008-01-11	Hoffmann La Roche	Imidazol-4-yl-ethynyl-pyridine derivatives
US7091222B2 (en) *	2003-07-03	2006-08-15	Hoffmann-La Roche Inc.	Imidazole derivatives
US7452909B2 (en) *	2003-09-04	2008-11-18	Hoffman-La Roche Inc.	Imidazole derivatives

2005
- 2005-05-23 PL PL05744719T patent/PL1756086T3/pl unknown
- 2005-05-23 WO PCT/EP2005/005559 patent/WO2005118568A1/en active Application Filing
- 2005-05-23 CA CA2568725A patent/CA2568725C/en not_active Expired - Fee Related
- 2005-05-23 AT AT05744719T patent/ATE397601T1/de active
- 2005-05-23 EP EP05744719A patent/EP1756086B1/en active Active
- 2005-05-23 CN CN200580017893XA patent/CN1960984B/zh not_active Expired - Fee Related
- 2005-05-23 AU AU2005250101A patent/AU2005250101B2/en not_active Ceased
- 2005-05-23 DE DE602005007350T patent/DE602005007350D1/de active Active
- 2005-05-23 RS RSP-2008/0394A patent/RS50603B/sr unknown
- 2005-05-23 MX MXPA06013603A patent/MXPA06013603A/es active IP Right Grant

Also Published As

Publication number	Publication date
AU2005250101A1 (en)	2005-12-15
AU2005250101B2 (en)	2011-08-25
EP1756086A1 (en)	2007-02-28
CA2568725C (en)	2012-11-27
RS50603B (sr)	2010-05-07
CN1960984B (zh)	2010-05-12
ATE397601T1 (de)	2008-06-15
CA2568725A1 (en)	2005-12-15
WO2005118568A1 (en)	2005-12-15
MXPA06013603A (es)	2007-02-08
DE602005007350D1 (de)	2008-07-17
EP1756086B1 (en)	2008-06-04
CN1960984A (zh)	2007-05-09

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