PH25902A - 1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics - Google Patents

1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics

Info

Publication number: PH25902A
Authority: PH; Philippines
Prior art keywords: indoles; analgesics; morpholinyl; alkyl; useful
Prior art date: 1987-02-11

Application number

PH36317A

Other languages

English (en)

Inventor

Thomas Edward D Ambra

Malcolm Rice Bell

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-11

Filing date

1988-01-04

Publication date

1991-12-19

1988-01-04 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1991-12-19 Publication of PH25902A publication Critical patent/PH25902A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PH36317A 1987-02-11 1988-01-04 1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics PH25902A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/013,313 US4840950A (en)	1987-02-11	1987-02-11	4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles

Publications (1)

Publication Number	Publication Date
PH25902A true PH25902A (en)	1991-12-19

Family

ID=21759325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH36317A PH25902A (en)	1987-02-11	1988-01-04	1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics

Country Status (21)

Country	Link
US (1)	US4840950A (fr)
EP (1)	EP0278265B1 (fr)
JP (1)	JP2561939B2 (fr)
KR (1)	KR960007523B1 (fr)
AR (1)	AR243184A1 (fr)
AT (1)	ATE80386T1 (fr)
AU (1)	AU596494B2 (fr)
CA (1)	CA1299180C (fr)
DE (1)	DE3874361T2 (fr)
DK (1)	DK167921B1 (fr)
ES (1)	ES2052608T3 (fr)
FI (1)	FI88152C (fr)
GR (1)	GR3005855T3 (fr)
IE (1)	IE63264B1 (fr)
IL (1)	IL84922A (fr)
MX (1)	MX174421B (fr)
NO (1)	NO169713C (fr)
NZ (1)	NZ223146A (fr)
PH (1)	PH25902A (fr)
PT (1)	PT86527B (fr)
ZA (1)	ZA879723B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5081122A (en) *	1990-03-05	1992-01-14	Sterling Drug Inc.	Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
CA2651732C (fr)	2006-05-18	2014-10-14	Mannkind Corporation	Inhibiteurs de kinases intracellulaires

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3182071A (en) *	1961-06-27	1965-05-04	Warner Lambert Pharmaceutical	Acylated indole derivatives
US3215699A (en) *	1961-06-27	1965-11-02	Warner Lambert Pharmaceutical	Substituted acetylphenyl hydrazones of 2,3-piperidine diones
US3494920A (en) *	1967-12-18	1970-02-10	American Home Prod	1-di(lower)alkylamino(lower)alkyl-3-(2-substituted ethyl) indoles
GB1374414A (en) *	1972-06-12	1974-11-20	Sterling Drug Inc	1-acyl-3-amino-alkyl-indoles and their preparation
GB1436771A (en) *	1973-02-16	1976-05-26	Labaz	Indole derivatives and process for preparing the same
US4581354A (en) *	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
PH23498A (en) *	1984-08-06	1989-08-16	Sterling Drug Inc	3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof

1987
- 1987-02-11 US US07/013,313 patent/US4840950A/en not_active Expired - Lifetime
- 1987-12-22 IL IL84922A patent/IL84922A/xx not_active IP Right Cessation
- 1987-12-29 ZA ZA879723A patent/ZA879723B/xx unknown
1988
- 1988-01-04 PH PH36317A patent/PH25902A/en unknown
- 1988-01-08 IE IE4788A patent/IE63264B1/en not_active IP Right Cessation
- 1988-01-11 NZ NZ223146A patent/NZ223146A/en unknown
- 1988-01-12 PT PT86527A patent/PT86527B/pt not_active IP Right Cessation
- 1988-01-12 FI FI880117A patent/FI88152C/fi not_active IP Right Cessation
- 1988-01-13 MX MX010085A patent/MX174421B/es unknown
- 1988-01-19 KR KR1019880000361A patent/KR960007523B1/ko not_active IP Right Cessation
- 1988-01-19 AU AU10387/88A patent/AU596494B2/en not_active Expired
- 1988-01-19 NO NO880206A patent/NO169713C/no not_active IP Right Cessation
- 1988-01-19 EP EP88100694A patent/EP0278265B1/fr not_active Expired - Lifetime
- 1988-01-19 DK DK021588A patent/DK167921B1/da not_active IP Right Cessation
- 1988-01-19 DE DE8888100694T patent/DE3874361T2/de not_active Expired - Lifetime
- 1988-01-19 AT AT88100694T patent/ATE80386T1/de not_active IP Right Cessation
- 1988-01-19 ES ES88100694T patent/ES2052608T3/es not_active Expired - Lifetime
- 1988-01-20 AR AR88309876A patent/AR243184A1/es active
- 1988-01-20 JP JP63010552A patent/JP2561939B2/ja not_active Expired - Lifetime
- 1988-01-26 CA CA000557313A patent/CA1299180C/fr not_active Expired - Lifetime
1992
- 1992-10-01 GR GR920401725T patent/GR3005855T3/el unknown

Also Published As

Publication number	Publication date
GR3005855T3 (fr)	1993-06-07
EP0278265A1 (fr)	1988-08-17
JP2561939B2 (ja)	1996-12-11
JPS63216865A (ja)	1988-09-09
PT86527A (en)	1988-02-01
FI880117A0 (fi)	1988-01-12
IE880047L (en)	1988-08-11
IE63264B1 (en)	1995-04-05
IL84922A (en)	1992-03-29
KR960007523B1 (ko)	1996-06-05
NO169713C (no)	1992-07-29
ES2052608T3 (es)	1994-07-16
DK167921B1 (da)	1994-01-03
AU596494B2 (en)	1990-05-03
DK21588D0 (da)	1988-01-19
ATE80386T1 (de)	1992-09-15
NO880206D0 (no)	1988-01-19
KR880009962A (ko)	1988-10-06
EP0278265B1 (fr)	1992-09-09
US4840950A (en)	1989-06-20
NO880206L (no)	1988-08-12
PT86527B (pt)	1991-12-31
DE3874361D1 (de)	1992-10-15
FI88152B (fi)	1992-12-31
MX10085A (es)	1993-09-01
NO169713B (no)	1992-04-21
DK21588A (da)	1988-08-12
DE3874361T2 (de)	1993-03-25
CA1299180C (fr)	1992-04-21
FI88152C (fi)	1993-04-13
MX174421B (es)	1994-05-16
ZA879723B (en)	1988-06-23
NZ223146A (en)	1990-01-29
FI880117A (fi)	1988-08-12
IL84922A0 (en)	1988-06-30
AR243184A1 (es)	1993-07-30
AU1038788A (en)	1988-08-18

Publication	Publication Date	Title
HK54592A (en)	1992-07-30	Shuttering
EP0277794A3 (en)	1989-10-25	N-heterocyclic-n-(4-piperidyl) amides
EP0320983A3 (en)	1990-10-10	Piperidinyl compounds
GB8712635D0 (en)	1987-07-01	Tools
GB2201104B (en)	1991-08-21	Concrete units
GB8721872D0 (en)	1987-10-21	Tombstones
GB8715178D0 (en)	1987-08-05	Shuttering
PH25902A (en)	1991-12-19	1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics
GB2201416B (en)	1990-06-20	Piperidine compounds
GB8717569D0 (en)	1987-09-03	Block
GB8712923D0 (en)	1987-10-21	Partitions
GB8701286D0 (en)	1987-02-25	Formwork
GB8709235D0 (en)	1987-05-20	Partitions
ZA888010B (en)	1989-06-28	New pyrrolidines
GB8704666D0 (en)	1987-04-01	Ties
GB2209664B (en)	1991-11-06	Trestles
GB8709238D0 (en)	1987-05-20	Partitions
GB8715028D0 (en)	1987-08-05	Corner block unit
ZA889281B (en)	1989-09-27	Piperidinyl compounds
ZA885289B (en)	1989-08-30	Blocks
GB8722671D0 (en)	1987-11-04	Trestles
AU101538S (en)	1988-10-06	Brochure unit
PL268745A1 (en)	1989-05-16	Upholstery staples block
HUT47670A (en)	1989-03-28	Space limiting structure
IE883506L (en)	1989-05-24	Piperidines