LT3380487T - Priedų sistemos, skirtos panaudoti baltymo pegilinime - Google Patents
Priedų sistemos, skirtos panaudoti baltymo pegilinimeInfo
- Publication number
- LT3380487T LT3380487T LTEP16816042.2T LT16816042T LT3380487T LT 3380487 T LT3380487 T LT 3380487T LT 16816042 T LT16816042 T LT 16816042T LT 3380487 T LT3380487 T LT 3380487T
- Authority
- LT
- Lithuania
- Prior art keywords
- additive systems
- protein pegylation
- pegylation
- protein
- additive
- Prior art date
Links
- 239000000654 additive Substances 0.000 title 1
- 230000000996 additive effect Effects 0.000 title 1
- 230000006320 pegylation Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562258644P | 2015-11-23 | 2015-11-23 | |
PCT/US2016/063313 WO2017091568A1 (en) | 2015-11-23 | 2016-11-22 | Additive systems for use in protein pegylation |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3380487T true LT3380487T (lt) | 2020-12-28 |
Family
ID=57589163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP16816042.2T LT3380487T (lt) | 2015-11-23 | 2016-11-22 | Priedų sistemos, skirtos panaudoti baltymo pegilinime |
Country Status (16)
Country | Link |
---|---|
US (3) | US10617765B2 (lt) |
EP (2) | EP3380487B1 (lt) |
JP (2) | JP6921821B2 (lt) |
KR (1) | KR102688003B1 (lt) |
CN (2) | CN108350025B (lt) |
CY (1) | CY1123699T1 (lt) |
DK (1) | DK3380487T3 (lt) |
ES (1) | ES2827776T3 (lt) |
HR (1) | HRP20201832T1 (lt) |
HU (1) | HUE052634T2 (lt) |
LT (1) | LT3380487T (lt) |
PL (1) | PL3380487T3 (lt) |
PT (1) | PT3380487T (lt) |
RS (1) | RS61072B1 (lt) |
SI (1) | SI3380487T1 (lt) |
WO (1) | WO2017091568A1 (lt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3380487B1 (en) * | 2015-11-23 | 2020-09-02 | Bristol-Myers Squibb Company | Additive systems for use in protein pegylation |
JP7441826B2 (ja) * | 2018-09-11 | 2024-03-01 | アンブルックス,インコーポレイテッド | インターロイキン-2ポリペプチド抱合物およびその使用 |
CN111484551B (zh) * | 2020-03-19 | 2022-02-11 | 北京翼方生物科技有限责任公司 | 一种聚乙二醇修饰的重组人碱性成纤维细胞生长因子 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19535571A1 (de) | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
TW518219B (en) | 1996-04-26 | 2003-01-21 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
EP0885613A1 (de) | 1997-06-21 | 1998-12-23 | Roche Diagnostics GmbH | Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin |
DE19734293A1 (de) | 1997-08-08 | 1999-02-11 | Boehringer Mannheim Gmbh | Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen |
JP5460958B2 (ja) * | 2004-03-17 | 2014-04-02 | アンチキャンサー インコーポレーテッド | タンパク質ポリエチレングリコール(peg)複合体形成を増大させる方法 |
EP1885404A2 (en) * | 2005-06-01 | 2008-02-13 | Alza Corporation | Bioconjugation reactions for acylating polyethlene glycol reagents |
CA2625540C (en) * | 2005-11-08 | 2017-03-21 | Ambrx, Inc. | Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides |
ATE554785T1 (de) * | 2007-03-30 | 2012-05-15 | Ambrx Inc | Modifizierte fgf-21 polypeptide und ihre verwendung |
KR102278630B1 (ko) | 2013-01-30 | 2021-07-16 | 아벨라스 바이오사이언시즈 인코포레이티드 | 선택적 전달 분자 및 사용 방법 |
WO2014176284A1 (en) | 2013-04-22 | 2014-10-30 | Avelas Biosciences, Inc. | Selective drug delivery compositions and methods of use |
PT3412302T (pt) | 2014-10-24 | 2021-06-09 | Bristol Myers Squibb Co | Polipéptidos de fgf-21 modificados e utilizações dos mesmos |
EP3380487B1 (en) * | 2015-11-23 | 2020-09-02 | Bristol-Myers Squibb Company | Additive systems for use in protein pegylation |
-
2016
- 2016-11-22 EP EP16816042.2A patent/EP3380487B1/en active Active
- 2016-11-22 PT PT168160422T patent/PT3380487T/pt unknown
- 2016-11-22 JP JP2018526713A patent/JP6921821B2/ja active Active
- 2016-11-22 DK DK16816042.2T patent/DK3380487T3/da active
- 2016-11-22 ES ES16816042T patent/ES2827776T3/es active Active
- 2016-11-22 CN CN201680067897.7A patent/CN108350025B/zh active Active
- 2016-11-22 LT LTEP16816042.2T patent/LT3380487T/lt unknown
- 2016-11-22 SI SI201630957T patent/SI3380487T1/sl unknown
- 2016-11-22 US US15/776,923 patent/US10617765B2/en active Active
- 2016-11-22 RS RS20201382A patent/RS61072B1/sr unknown
- 2016-11-22 HU HUE16816042A patent/HUE052634T2/hu unknown
- 2016-11-22 WO PCT/US2016/063313 patent/WO2017091568A1/en active Application Filing
- 2016-11-22 EP EP20189107.4A patent/EP3789395A1/en active Pending
- 2016-11-22 CN CN202211743414.4A patent/CN115819494A/zh active Pending
- 2016-11-22 PL PL16816042T patent/PL3380487T3/pl unknown
- 2016-11-22 KR KR1020187017508A patent/KR102688003B1/ko active IP Right Grant
-
2020
- 2020-02-21 US US16/797,361 patent/US11213589B2/en active Active
- 2020-11-19 HR HRP20201832TT patent/HRP20201832T1/hr unknown
- 2020-11-20 CY CY20201101102T patent/CY1123699T1/el unknown
-
2021
- 2021-07-28 JP JP2021123154A patent/JP7257457B2/ja active Active
- 2021-12-03 US US17/541,636 patent/US20220160883A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP7257457B2 (ja) | 2023-04-13 |
EP3380487B1 (en) | 2020-09-02 |
US20200276319A1 (en) | 2020-09-03 |
US11213589B2 (en) | 2022-01-04 |
CY1123699T1 (el) | 2022-03-24 |
WO2017091568A8 (en) | 2018-01-04 |
KR102688003B1 (ko) | 2024-07-23 |
EP3789395A1 (en) | 2021-03-10 |
US20220160883A1 (en) | 2022-05-26 |
DK3380487T3 (da) | 2020-12-07 |
CN108350025B (zh) | 2023-02-21 |
JP2019503994A (ja) | 2019-02-14 |
ES2827776T3 (es) | 2021-05-24 |
CN115819494A (zh) | 2023-03-21 |
US10617765B2 (en) | 2020-04-14 |
JP6921821B2 (ja) | 2021-08-18 |
WO2017091568A1 (en) | 2017-06-01 |
US20190351065A1 (en) | 2019-11-21 |
PT3380487T (pt) | 2020-10-29 |
RS61072B1 (sr) | 2020-12-31 |
JP2021176890A (ja) | 2021-11-11 |
KR20180081610A (ko) | 2018-07-16 |
SI3380487T1 (sl) | 2020-11-30 |
HRP20201832T1 (hr) | 2021-01-08 |
PL3380487T3 (pl) | 2020-12-28 |
EP3380487A1 (en) | 2018-10-03 |
HUE052634T2 (hu) | 2021-05-28 |
CN108350025A (zh) | 2018-07-31 |
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