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LT3380487T - Priedų sistemos, skirtos panaudoti baltymo pegilinime - Google Patents

Priedų sistemos, skirtos panaudoti baltymo pegilinime

Info

Publication number
LT3380487T
LT3380487T LTEP16816042.2T LT16816042T LT3380487T LT 3380487 T LT3380487 T LT 3380487T LT 16816042 T LT16816042 T LT 16816042T LT 3380487 T LT3380487 T LT 3380487T
Authority
LT
Lithuania
Prior art keywords
additive systems
protein pegylation
pegylation
protein
additive
Prior art date
Application number
LTEP16816042.2T
Other languages
English (en)
Inventor
Matthew R. Hickey
Antonio Ramirez
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of LT3380487T publication Critical patent/LT3380487T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/64Relaxins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LTEP16816042.2T 2015-11-23 2016-11-22 Priedų sistemos, skirtos panaudoti baltymo pegilinime LT3380487T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562258644P 2015-11-23 2015-11-23
PCT/US2016/063313 WO2017091568A1 (en) 2015-11-23 2016-11-22 Additive systems for use in protein pegylation

Publications (1)

Publication Number Publication Date
LT3380487T true LT3380487T (lt) 2020-12-28

Family

ID=57589163

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP16816042.2T LT3380487T (lt) 2015-11-23 2016-11-22 Priedų sistemos, skirtos panaudoti baltymo pegilinime

Country Status (16)

Country Link
US (3) US10617765B2 (lt)
EP (2) EP3380487B1 (lt)
JP (2) JP6921821B2 (lt)
KR (1) KR102688003B1 (lt)
CN (2) CN108350025B (lt)
CY (1) CY1123699T1 (lt)
DK (1) DK3380487T3 (lt)
ES (1) ES2827776T3 (lt)
HR (1) HRP20201832T1 (lt)
HU (1) HUE052634T2 (lt)
LT (1) LT3380487T (lt)
PL (1) PL3380487T3 (lt)
PT (1) PT3380487T (lt)
RS (1) RS61072B1 (lt)
SI (1) SI3380487T1 (lt)
WO (1) WO2017091568A1 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3380487B1 (en) * 2015-11-23 2020-09-02 Bristol-Myers Squibb Company Additive systems for use in protein pegylation
JP7441826B2 (ja) * 2018-09-11 2024-03-01 アンブルックス,インコーポレイテッド インターロイキン-2ポリペプチド抱合物およびその使用
CN111484551B (zh) * 2020-03-19 2022-02-11 北京翼方生物科技有限责任公司 一种聚乙二醇修饰的重组人碱性成纤维细胞生长因子

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19535571A1 (de) 1995-09-14 1997-03-20 Boehringer Mannheim Gmbh Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten
TW518219B (en) 1996-04-26 2003-01-21 Chugai Pharmaceutical Co Ltd Erythropoietin solution preparation
EP0885613A1 (de) 1997-06-21 1998-12-23 Roche Diagnostics GmbH Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin
DE19734293A1 (de) 1997-08-08 1999-02-11 Boehringer Mannheim Gmbh Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen
JP5460958B2 (ja) * 2004-03-17 2014-04-02 アンチキャンサー インコーポレーテッド タンパク質ポリエチレングリコール(peg)複合体形成を増大させる方法
EP1885404A2 (en) * 2005-06-01 2008-02-13 Alza Corporation Bioconjugation reactions for acylating polyethlene glycol reagents
CA2625540C (en) * 2005-11-08 2017-03-21 Ambrx, Inc. Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
ATE554785T1 (de) * 2007-03-30 2012-05-15 Ambrx Inc Modifizierte fgf-21 polypeptide und ihre verwendung
KR102278630B1 (ko) 2013-01-30 2021-07-16 아벨라스 바이오사이언시즈 인코포레이티드 선택적 전달 분자 및 사용 방법
WO2014176284A1 (en) 2013-04-22 2014-10-30 Avelas Biosciences, Inc. Selective drug delivery compositions and methods of use
PT3412302T (pt) 2014-10-24 2021-06-09 Bristol Myers Squibb Co Polipéptidos de fgf-21 modificados e utilizações dos mesmos
EP3380487B1 (en) * 2015-11-23 2020-09-02 Bristol-Myers Squibb Company Additive systems for use in protein pegylation

Also Published As

Publication number Publication date
JP7257457B2 (ja) 2023-04-13
EP3380487B1 (en) 2020-09-02
US20200276319A1 (en) 2020-09-03
US11213589B2 (en) 2022-01-04
CY1123699T1 (el) 2022-03-24
WO2017091568A8 (en) 2018-01-04
KR102688003B1 (ko) 2024-07-23
EP3789395A1 (en) 2021-03-10
US20220160883A1 (en) 2022-05-26
DK3380487T3 (da) 2020-12-07
CN108350025B (zh) 2023-02-21
JP2019503994A (ja) 2019-02-14
ES2827776T3 (es) 2021-05-24
CN115819494A (zh) 2023-03-21
US10617765B2 (en) 2020-04-14
JP6921821B2 (ja) 2021-08-18
WO2017091568A1 (en) 2017-06-01
US20190351065A1 (en) 2019-11-21
PT3380487T (pt) 2020-10-29
RS61072B1 (sr) 2020-12-31
JP2021176890A (ja) 2021-11-11
KR20180081610A (ko) 2018-07-16
SI3380487T1 (sl) 2020-11-30
HRP20201832T1 (hr) 2021-01-08
PL3380487T3 (pl) 2020-12-28
EP3380487A1 (en) 2018-10-03
HUE052634T2 (hu) 2021-05-28
CN108350025A (zh) 2018-07-31

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