LT2805731T - Stabilios polipeptidų kompozicijos ir jų panaudojimas - Google Patents
Stabilios polipeptidų kompozicijos ir jų panaudojimasInfo
- Publication number
- LT2805731T LT2805731T LTEP14171120.0T LT14171120T LT2805731T LT 2805731 T LT2805731 T LT 2805731T LT 14171120 T LT14171120 T LT 14171120T LT 2805731 T LT2805731 T LT 2805731T
- Authority
- LT
- Lithuania
- Prior art keywords
- polypeptides
- stable formulations
- formulations
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27581609P | 2009-09-03 | 2009-09-03 | |
US28450209P | 2009-12-18 | 2009-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2805731T true LT2805731T (lt) | 2019-02-11 |
Family
ID=42797362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP14171120.0T LT2805731T (lt) | 2009-09-03 | 2010-09-03 | Stabilios polipeptidų kompozicijos ir jų panaudojimas |
Country Status (12)
Country | Link |
---|---|
US (2) | US20120244158A1 (lt) |
EP (5) | EP3725330A1 (lt) |
CY (1) | CY1121411T1 (lt) |
DK (2) | DK2473527T3 (lt) |
ES (3) | ES2617180T3 (lt) |
HK (1) | HK1204284A1 (lt) |
HR (1) | HRP20190137T1 (lt) |
LT (1) | LT2805731T (lt) |
PL (2) | PL3438126T3 (lt) |
PT (3) | PT2473528E (lt) |
SI (1) | SI2805731T1 (lt) |
WO (2) | WO2011026945A1 (lt) |
Families Citing this family (29)
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AU2008252853B2 (en) | 2007-05-24 | 2011-12-01 | Ablynx N.V. | Amino acid sequences directed against RANK-L and polypeptides comprising the same for the treatment of bone diseases and disorders |
RU2481824C2 (ru) | 2008-10-29 | 2013-05-20 | Аблинкс Н.В | Препараты однодоменных антигенсвязывающих молекул |
AU2009314311B2 (en) | 2008-10-29 | 2013-01-10 | Ablynx N.V. | Methods for purification of single domain antigen binding molecules |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
US10005830B2 (en) | 2009-03-05 | 2018-06-26 | Ablynx N.V. | Antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
WO2010115995A2 (en) | 2009-04-10 | 2010-10-14 | Ablynx Nv | Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders |
JP5647222B2 (ja) | 2009-04-10 | 2014-12-24 | アブリンクス エン.ヴェー. | Il−6r関連疾患及び障害の治療のためのil−6rに指向性を有する改善されたアミノ酸配列及びこれを含むポリペプチド |
LT2805731T (lt) * | 2009-09-03 | 2019-02-11 | Ablynx N.V. | Stabilios polipeptidų kompozicijos ir jų panaudojimas |
EP2473191B1 (en) * | 2009-09-04 | 2017-08-23 | XOMA Technology Ltd. | Antibody coformulations |
PL2533761T3 (pl) | 2010-02-11 | 2019-09-30 | Ablynx N.V. | Sposoby i kompozycje do wytwarzania aerozoli |
DK2542257T3 (en) | 2010-03-01 | 2017-10-16 | Bayer Healthcare Llc | OPTIMIZED MONOCLONAL ANTIBODIES AGAINST Tissue FACTOR ROAD INHIBITOR (TFPI) |
WO2011161263A1 (en) | 2010-06-25 | 2011-12-29 | Ablynx Nv | Pharmaceutical compositions for cutaneous administration |
US9044498B2 (en) * | 2010-12-02 | 2015-06-02 | Oncolytics Biotech Inc. | Lyophilized viral formulations |
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CA2835340A1 (en) * | 2011-05-27 | 2012-12-06 | Ablynx Nv | Inhibition of bone resorption with rankl binding peptides |
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EP2747782B1 (en) * | 2011-09-23 | 2018-01-17 | Ablynx NV | Prolonged inhibition of interleukin-6 mediated signaling |
US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
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AU2015334984A1 (en) | 2014-10-21 | 2017-04-13 | Ablynx Nv | Treatment of IL-6R related diseases |
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WO2018007442A1 (en) | 2016-07-06 | 2018-01-11 | Ablynx N.V. | Treatment of il-6r related diseases |
WO2018029182A1 (en) | 2016-08-08 | 2018-02-15 | Ablynx N.V. | Il-6r single variable domain antibodies for treatment of il-6r related diseases |
KR102616335B1 (ko) * | 2017-02-28 | 2023-12-21 | 브이아이비 브이지더블유 | 경구 단백질 전달을 위한 수단 및 방법 |
CN118894939A (zh) | 2017-06-02 | 2024-11-05 | 默克专利股份有限公司 | 结合adamts的免疫球蛋白 |
WO2020185479A1 (en) * | 2019-03-08 | 2020-09-17 | Boehringer Ingelheim International Gmbh | Anti-il-36r antibody formulations |
BR112022026999A2 (pt) | 2020-07-17 | 2023-01-24 | Boehringer Ingelheim Int | Anticorpos anti-il-36r para tratamento de dermatoses neutrofílicas |
CN114681592A (zh) * | 2020-12-31 | 2022-07-01 | 天境生物科技(杭州)有限公司 | 包含可溶性gp130二聚体的制剂和使用方法 |
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SG10201704214VA (en) * | 2009-01-29 | 2017-06-29 | Medimmune Llc | Human anti-il-6 antibodies with extended in vivo half-life and their use in treatment of oncology, autoimmune diseases and inflammatory diseases |
US10005830B2 (en) * | 2009-03-05 | 2018-06-26 | Ablynx N.V. | Antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
LT2805731T (lt) * | 2009-09-03 | 2019-02-11 | Ablynx N.V. | Stabilios polipeptidų kompozicijos ir jų panaudojimas |
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2010
- 2010-09-03 LT LTEP14171120.0T patent/LT2805731T/lt unknown
- 2010-09-03 PL PL18185772T patent/PL3438126T3/pl unknown
- 2010-09-03 DK DK10747895.0T patent/DK2473527T3/en active
- 2010-09-03 ES ES10747895.0T patent/ES2617180T3/es active Active
- 2010-09-03 PL PL10747896T patent/PL2473528T3/pl unknown
- 2010-09-03 US US13/393,636 patent/US20120244158A1/en not_active Abandoned
- 2010-09-03 EP EP20176028.7A patent/EP3725330A1/en active Pending
- 2010-09-03 EP EP14171120.0A patent/EP2805731B1/en active Active
- 2010-09-03 PT PT10747896T patent/PT2473528E/pt unknown
- 2010-09-03 PT PT181857723T patent/PT3438126T/pt unknown
- 2010-09-03 EP EP10747895.0A patent/EP2473527B1/en active Active
- 2010-09-03 EP EP18185772.3A patent/EP3438126B1/en active Active
- 2010-09-03 SI SI201031846T patent/SI2805731T1/sl unknown
- 2010-09-03 EP EP10747896.8A patent/EP2473528B1/en active Active
- 2010-09-03 ES ES10747896T patent/ES2531083T3/es active Active
- 2010-09-03 ES ES18185772T patent/ES2831323T3/es active Active
- 2010-09-03 PT PT107478950T patent/PT2473527T/pt unknown
- 2010-09-03 WO PCT/EP2010/062972 patent/WO2011026945A1/en active Application Filing
- 2010-09-03 US US13/393,679 patent/US9884117B2/en active Active
- 2010-09-03 WO PCT/EP2010/062975 patent/WO2011026948A1/en active Application Filing
- 2010-09-03 DK DK10747896T patent/DK2473528T3/en active
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2015
- 2015-05-22 HK HK15104885.3A patent/HK1204284A1/xx not_active IP Right Cessation
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2019
- 2019-01-21 HR HRP20190137TT patent/HRP20190137T1/hr unknown
- 2019-01-31 CY CY20191100137T patent/CY1121411T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL3438126T3 (pl) | 2021-03-08 |
WO2011026948A1 (en) | 2011-03-10 |
DK2473528T3 (en) | 2015-03-02 |
ES2617180T3 (es) | 2017-06-15 |
US20120244158A1 (en) | 2012-09-27 |
ES2531083T3 (es) | 2015-03-10 |
PL2473528T3 (pl) | 2015-05-29 |
EP2473527A1 (en) | 2012-07-11 |
PT3438126T (pt) | 2020-11-09 |
HK1204284A1 (en) | 2015-11-13 |
EP2805731B1 (en) | 2018-10-31 |
WO2011026945A1 (en) | 2011-03-10 |
PT2473527T (pt) | 2017-02-27 |
PT2473528E (pt) | 2015-03-04 |
EP2473528B1 (en) | 2014-12-03 |
US9884117B2 (en) | 2018-02-06 |
ES2831323T3 (es) | 2021-06-08 |
EP3438126A1 (en) | 2019-02-06 |
EP3438126B1 (en) | 2020-08-19 |
EP2473528A1 (en) | 2012-07-11 |
US20120201812A1 (en) | 2012-08-09 |
HRP20190137T1 (hr) | 2019-03-22 |
EP2805731A3 (en) | 2015-04-01 |
CY1121411T1 (el) | 2020-05-29 |
DK2473527T3 (en) | 2017-03-06 |
EP2805731A2 (en) | 2014-11-26 |
EP2473527B1 (en) | 2016-11-30 |
EP3725330A1 (en) | 2020-10-21 |
SI2805731T1 (sl) | 2019-02-28 |
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