Nothing Special   »   [go: up one dir, main page]

KR930702514A - 리파제 변체 - Google Patents

리파제 변체

Info

Publication number
KR930702514A
KR930702514A KR1019930700773A KR930700773A KR930702514A KR 930702514 A KR930702514 A KR 930702514A KR 1019930700773 A KR1019930700773 A KR 1019930700773A KR 930700773 A KR930700773 A KR 930700773A KR 930702514 A KR930702514 A KR 930702514A
Authority
KR
South Korea
Prior art keywords
lipase
lipase variant
amino acid
variant
porridge
Prior art date
Application number
KR1019930700773A
Other languages
English (en)
Inventor
알란 스벤드센
입 그로트 클라우젠
샴칸트 아난트 파트카아
에릭 고름센
Original Assignee
안네 제케르
노보 노르디스크 아크티에 셀스카브
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK219490A external-priority patent/DK219490D0/da
Priority claimed from DK219590A external-priority patent/DK219590D0/da
Priority claimed from DK219690A external-priority patent/DK219690D0/da
Application filed by 안네 제케르, 노보 노르디스크 아크티에 셀스카브 filed Critical 안네 제케르
Publication of KR930702514A publication Critical patent/KR930702514A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Seal Device For Vehicle (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

포켓이 지질접촉 부위의 부분을 형성하고 지절접촉부에 의해 둘러싸인 리파제 분자의 우세하게 소수성인 연장된 결합포켓내에 위치된 활성세린을 포함하는 트립신-같은 촉매 3체를 함유하는 리파제가 지질접촉부의 정전기적 전하 및/또는 소수성을 변화시키기 위해서 또는 리파제의 지질접촉부의 표면형태를 변화시키기 위해서 지질접촉부내의 하나 이상의 아미노산 잔기의 삭제 또는 치환에 의해 돌연변이 되었다.

Description

리파제 변체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1A 및 B도는 리파제가 각기 불활성(A) 및 활성(B)형태일때 H·lanuginosa 리파제의 지질접촉부의 3-차원 구조를 나타내는 컴퓨터 모델이다, 제2A 및 2B도는 리파제가 각기 불황성(A) 및 활성(B)형태일때 Rh·miehei 리파제의 지질접촉부의 3-차원 구조를 나타내는 컴퓨터 모델이다.

Claims (161)

  1. 리파제 분자의 우세하게 소수성인 연장된 결합포켓내에 위치된 활성세린을 포함하는 트립신-같은 촉매 3체를 함유하는 모(母) 리파제의 리파제 변체에 있어서, 가수분해시 또는 가수분해 동안 기질과의 상호작용에 참여할 수 있는 활성세린 잔기를 포함하는 리파제 구조부내에 위치된 잔기들을 함유하는 지질 접촉부의 정전기적 전하 및/또는 소수성이 하나 이상의 음전하 아미노산잔기를 중성의 또는 양전하의 아미노산잔기(들)에 의해 치환 또는 삭제함에 의하여, 및/또는 하나 이상의 중성의 아미노산 잔기를 양전하 잔기를 소수성 아미노산잔기(들)에 의해 치환 또는 삭제함에 의하여 변화되는 것을 특징으로 하는 리파제 변체.
  2. 제1항에 있어서, 상기의 지질 접촉부의 하나 이상의 글루탐산, 아스파르트산 잔기가 글루타민, 아스파라긴, 알라닌, 류신, 발린, 세린, 트레오닌, 리신, 또는 아르기닌에 의해 치환되는 것을 특징으로 하는 리파제 변체.
  3. 제1항 내지 제2항중 어느 하나에 있어서, 모 리파제가 미생물의 리파제인 것을 특징으로 하는 리파제 변체.
  4. 제3항에 있어서, 모 리파제가 곰팡이의 리파제인 것을 특징으로 하는 리파제 변체.
  5. 제4항에 있어서, 모 리파제가 Humicola, 또는 Rhizomucor 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  6. 제5항에 있어서, 모 리파제가 Rhizomucor miehei 리파제인 것을 특징으로 하는 리파제 변체.
  7. 제6항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이, 치환되는 것을 특징으로 하는 리파제 변체 :
  8. D 91N, K, R, A, V, L, S, T,
  9. D256N, K, R, A, V, L, S, T,
  10. D226N, K, R, A, V, L, S, T,
  11. D 61N, K, R, A, V, L, S, T,
  12. D113N, K, R, A, V, L, S, T,
  13. E201Q, K, R, A, V, L, S, T,
  14. D243N, K, R, A, V, L, S, T.
  15. 제5항에 있어서, 모 리파제가Humicola Rhizomucor리파제인 것을 특징으로 하는 리파제 변체.
  16. 제8항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  17. E 87Q, K, R, A, N, T, S, L, V,
  18. D254N, K, R, A, N, T, S, L, V,
  19. D242N, K, R, A, N, T, S, L, V,
  20. E210Q, K, R, A, N, T, S, L, V,
  21. E 56Q, K, R, A, N, T, S, L, V,
  22. D 96N, K, R, A, N, T, S, L, V,
  23. D111N, K, R, A, N, T, S, L, V,
  24. D 62A, Q, N, T, S, K, R, L, V,
  25. E219A, Q, N, T, S, K, R, L, V,
  26. E234A, Q, N, T, S, K, R, L, V,
  27. E 57A, Q, N, T, S, K, R, L, V,
  28. E 99A, Q, N, T, S, K, R, L, V,
  29. D 27A, Q, N, T, S, K, R, L, V, 또는
  30. E239A, Q, N, T, S, K, R, L, V.
  31. 제9항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  32. E87Q+D254N+D242N+E210Q,
  33. E87Q+D254N+E210Q,
  34. E96N+E87Q+D254N,
  35. R209A+E210A.
  36. 제8항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  37. T267K, R,
  38. S 85K, R,
  39. T226K, R,
  40. N 88K, R,
  41. N 92K, R,
  42. I255K, R,
  43. I202K, R,
  44. L206K, R,
  45. L259K, R,
  46. V202K, R, 또는
  47. L227K, R
  48. 제4항에 있어서, 모 리파제가 효모 리파제인 것을 특징으로 하는 리파제 변체.
  49. 제12항에 있어서, 모 리파제가 Candida 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  50. 제3항에 있어서, 모 리파제가 세균의 리파제인 것을 특징으로 하는 리파제 변체.
  51. 제14항에 있어서, 모 리파제가 Pseudomonas 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  52. 리파제 분자의 우세하게 소수성인 연장된 결합포켓내에 위치된 활성세린을 포함하는 트립신-같은 촉매 3체를 함유하는 리파제 변체에 있어서, 상기의 리파제 변체가 지질 접촉부의 표면형태를 변화시키기 위해서 가수분해시 또는 가수분해 동안 기질과의 상호작용에 참여하는 활성세린 잔기를 포함하는 리파제 구조부내에 위치된 잔가딜을 함유하는 지질 접촉부의 서열을 구성하는 하나 이상의 아미노산 잔기의 위치에 하나 이상의 아미노산 잔기가 치환, 삭제, 또는 삽입된 것을 특징으로 하는 리파제 변체.
  53. 제16항에 있어서, 하나 이상의 아미노산 잔기가 하나 이상의 다른 덜 부피있는 아미노산 잔기에 의하여 치환된 것을 특징으로 하는 리파제 변체.
  54. 제17항에 있어서, 하나 이상의 아미노산 잔기가 발린, 트레오닌, 세린, 글리신, 또는 알라닌에 의해 치환된 것을 특징으로 하는 리파제 변체.
  55. 제16항에 있어서, 지질 접촉부내의 고리서열부를 형성하는 하나 이상의 아미노산 잔기가 삭제된 것을 특징으로 하는 리파제 변체.
  56. 제19항에 있어서, 2-8, 특히 2-6 아미노산 잔기가 지질 접촉부내의 하나 이상의 고리서열로 부터 삭제된 것을 특징으로 하는 리파제 변체.
  57. 제16항 내지 제20항중 어느 하나에 있어서, 모 리파제가 미생물의 리파제인 것을 특징으로 하는 리파제 변체.
  58. 제21항에 있어서, 모 리파제가 곰팡이의 리파제인 것을 특징으로 하는 리파제 변체.
  59. 제22항에 있어서, 모 리파제가 Humicola 또는 Rhizomucor 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  60. 제23항에 있어서, 모 리파제가 Rhizomucor miehei 리파제인 것을 특징으로 하는 리파제 변체.
  61. 제24항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  62. I204V, A, T, S, G,
  63. L208V, A, T, S, G,
  64. F213V, A, T, S, G, 또는
  65. I254V, A, T, S, G.
  66. 제24항에 있어서, 하나 이상의 아미노산 잔기가 하기의 위치중 하나 이상에서 삭제된 것을 특징으로 하는 리파제 변체 :
  67. 82-113, 211-215, 235-243, 245-269 또는 264-269
  68. 제26항에 있어서, 하기와 같이 변형된 것을 특징으로 하는 리파제 변체 :
  69. N264*+T265*+G266*+L267*+C268*+T269*+C22T.
  70. 제26항에 있어서, 하기의 아미노산 잔기가 삭제된 것을 특징으로 하는 리파제 변체 :
  71. F213*+F215*
  72. D238*+L239*+E240*+D243*, 또는
  73. F251*+T252*+S247*
  74. 제23항에 있어서, 모 리파제가Humicola lanuginosa리파제인 것을 특징으로 하는 리파제 변체.
  75. 제29항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  76. I202V, A, T, S, G,
  77. L206V, A, T, S, G,
  78. F211V, A, T, S, G, 또는
  79. I255V, A, T, S, G.
  80. 제29항에 있어서, 하나 이상의 아미노산 잔기가 하기의 위치중 하나 이상에서 삭제된 것을 특징으로 하는 리파제 변체 :
  81. 82-112, 209-213, 238-245, 247-254 또는 264-269.
  82. 제31항에 있어서, 하기와 같이 변형된 것을 특징으로 하는 리파제 변체 :
  83. N264*+T265*+G266*+L267*+C268*+T269*+C22T.
  84. 제31항에 있어서, 하기의 아미노산 잔기가 삭제된 것을 특징으로 하는 리파제 변체 :
  85. R209*+E210*
  86. F211*+Y213*
  87. D242*+E239*+I241, 또는
  88. N247*+D254*
  89. 제21항에 있어서, 모 리파제가 효모 리파제인 것을 특징으로 하는 리파제 변체.
  90. 제34항에 있어서, 모 리파제가 Candida 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  91. 제21항에 있어서, 모 리파제가 세균의 리파제인 것을 특징으로 하는 리파제 변체.
  92. 제36항에 있어서, 모 리파제가Pseudomonas균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  93. (i)리파제 분자의 우세하게 소수성인 연장된 결합포켓내에 위치된 활성세린을 포함하는 트립신-같은 촉매 3체 및 (ii)리파제가 불활성 형태일때 활성세린을 덮고 리파제가 활성세린을 지질 기질에 접근가능하게 만들기 위해 활성화될때 그것의 형태를 변화시키는 표면고리구조, 여기서 고리구조는 결합포켓에 면한 우세하게 소수성인 안쪽 표면과 우세하게 친수성인 바깥쪽 표면을 가지는 것을 함유하는 유형의 리파제 변체에 있어서, 상기의 리파제 변체가 가수분해시 또는 가수분해 동안 기질과의 상호작용 또는 표면고리구조를 이동시키는 것에 참여하는 활성세린 잔기를 포함하는 리파제 구조부내에 위치된 잔기들을 함유하는 지질 접촉부 서열을 구성하는 및/또는 고리구조의 서열을 구성하는 하나 이상의 아미노산 잔기의 위치에 하나 이상의 아미노산 잔기가 치환, 삭제, 또는 삽입된 것을 특징으로 하는 리파제 변체.
  94. 제38항에 있어서, 고리구조의 적어도 하나의 아미노산 잔기가 시스테인에 의해 치환되고, 및 적어도 하나의 다른 아미노산 잔기가 시스테인에 의해 치환되고, 두시스테인 잔기가 서로서로에 대해 이황화물 결합을 형성하도록 위치되는 것을 특징으로 하는 라파제 변체.
  95. 제38항 내지 제39항중 있어서, 모 리파제가 미생물의 리파제인 것을 특징으로 하는 리파제 변체.
  96. 제38항 내지 제40항중 어느 하나에 있어서, 모 리파제가 곰팡이의 리파제인 것을 특징으로 하는 리파제 변체.
  97. 제41항에 있어서, 모 리파제가 Humicola, 또는 Rhizomucor 균주로 부터 추출되는 것을 특징으로 하는 리파제 변체.
  98. 제42항에 있어서, 모 리파제가 Rhizomucor miehei 리파제인 것을 특징으로 하는 리파제 변체.
  99. 제43항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  100. S114C+A90C
  101. R 86C+D61C,
  102. S 84C+D61C,
  103. N 74C+D61C,
  104. Y 60C+R78C, 또는
  105. Y 60C+B87C,
  106. 제43항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이 치환되는 것을 특징으로 하는 리파제 변체 :
  107. I240V, T, S, A, G,
  108. L208V, T, S, A, G,
  109. V254V, T, S, A, G,
  110. L255V, T, S, A, G,
  111. L258V, T, S, A, G,
  112. L267V, T, S, A, G,
  113. F 94L, T, K, 또는
  114. F213L, T, K
  115. 제43항에 있어서, 하기의 아미노산 치환을 포함하는 것을 특징으로 하는 리파제 변체 :
  116. I204T+ :255T+L257T, 또는
  117. L208T+ V254T+L258T
  118. 제42항에 있어서, 모 리파제가 Humicola, 또는 lanuginosa 리파제인 것을 특징으로 하는 리파제 변체.
  119. 제47항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이, 치환되는 것을 특징으로 하는 리파제 변체:
  120. G 61C+N88C,
  121. G 61C+E87C,
  122. D 62C+E87C,
  123. D 62C+S85C,
  124. D 62C+N88C, 또는
  125. S116C+G91C
  126. 제47항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이, 치환되는 것을 특징으로 하는 리파제 변체:
  127. L 93V, T, S, A, G,
  128. I 90V, T, S, A, G,
  129. I 86V, T, S, A, G,
  130. I202V, T, S, A, G,
  131. I206V, T, S, A, G,
  132. I255V, T, S, A, G,
  133. L259V, T, S, A, G,
  134. I265V, T, S, A, G,
  135. F 95L, T, K, 또는
  136. F211L, T, K,
  137. 제49항에 있어서, 하나 이상의 아미노산 잔기가 하기와 같이, 치환되는 것을 특징으로 하는 리파제 변체:
  138. F 95K,
  139. I 86T,
  140. I 90T,
  141. I255T,
  142. L259T,
  143. L206T, 또는
  144. L206T+I255T+L259T
  145. 제40항에 있어서, 모 리파제가 효모 리파제인 것을 특징으로 하는 리파제 변체.
  146. 제51항에 있어서, 모 리파제가Candida균주로 부터 추출되는 것을 특징으로 하는 리파제 변체:
  147. 제40항에 있어서, 모 리파제가 세균의 리파제인 것을 특징으로 하는 리파제 변체:
  148. 제53항에 있어서, 모 리파제가Pseudomonas균주로 부터 추출되는 것을 특징으로 하는 리파제 변체:
  149. 제1항 내지 제54항중 어느 하나에 따른 리파제 변체를 암호화하는 DNA 서열을 포함하는 DNA 구조체.
  150. 제55항에 따른 DNA 구조체를 운반하는 재조합 발현벡터.
  151. 제55항에 따른 DNA 구조체를 운반하는 재조합 발현벡터.
  152. 제57항에 있어서, 곰팡이, 세포, 예컨대,A.niger,A.oryzae또는A.nidulans따위의 속Aspergillus에 속하는 곰팡이세포, 효모세포, 예컨대S.cerevisiae따위의Saccharomyces균주에 속하는 효모세포, 또는H.polymorpha따위의 속Hansenula의 또는P.pastoris따위의 속Phichia의 메틸로트로픽 효모(methylotrophic yeast), 또는 세균세포, 예컨대B.subtilis,B.lentus따위의Bacillus균주에 속하는 세균 세포인 것을 특징으로 하는 세포.
  153. 제57항에 있어서, 식물세포, 예컨대Solamun tuberosum, 또는Nicotiana tabacum따위의Solanaceae에 속하는 식물세포인 것을 특징으로 하는 세포.
  154. 제59항에 따른 세포를 함유하는 식물.
  155. 제1항 내지 제54항중 어느 하나에 따른 리파제 변체의 제조방법에서, 제57항 내지 제59항중 어느 하나에 따른 세포, 또는 제60항에 따른 식물이 리파제 변체의 제조에 도움이 되는 조건하에서 배양 또는 생장되고 그 다음에 리파제 변체가 배양물 또는 식물체로 부터 회수되는 것을 특징으로 하는 리파제 변체 제조방법.
  156. 제1항 내지 제54항중 어느 하나에 따른 리파제 변체를 포함하는 세정제 첨가물에서, 선택적으로 비-살포성 과립, 안정화된 액체 또는 보호된 효소의 형태의 세정제 첨가물.
  157. 제62항에 있어서, 첨가물 g당 효소 단백질을 0.02-200mg 포함하는 것을 특징으로 하는 세정제 첨가물.
  158. 제62항 또는 제63항에 있어서, 부가적으로 프로테아제, 아밀라제, 퍼옥시다제 및/또는 셀룰라제 따위의 다른 효소를 포함하는 것을 특징으로 하는 세정제 첨가물.
  159. 제1항 내지 54항중 어느 하나에 따른 리파제 변체를 함유하는 세정제 조성물.
  160. 제65항에 있어서, 부가적으로 프로테아제, 아밀라제, 퍼옥시다제 및/또는 셀룰라제 따위의 다른 효소를 포함하는 것을 특징으로 하는 세정제 조성물.
  161. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930700773A 1990-09-13 1991-09-13 리파제 변체 KR930702514A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DK219490A DK219490D0 (da) 1990-09-13 1990-09-13 Enzymmutanter
DK2194/90 1990-09-13
DK2196/92 1990-09-13
DK2195/90 1990-09-13
DK219590A DK219590D0 (da) 1990-09-13 1990-09-13 Lipasemutanter
DK219690A DK219690D0 (da) 1990-09-13 1990-09-13 Lipasevarianter
PCT/DK1991/000271 WO1992005249A1 (en) 1990-09-13 1991-09-13 Lipase variants

Publications (1)

Publication Number Publication Date
KR930702514A true KR930702514A (ko) 1993-09-09

Family

ID=27221523

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930700773A KR930702514A (ko) 1990-09-13 1991-09-13 리파제 변체

Country Status (12)

Country Link
EP (1) EP0548228B1 (ko)
JP (1) JP3469234B2 (ko)
KR (1) KR930702514A (ko)
AT (1) ATE169671T1 (ko)
AU (1) AU657278B2 (ko)
BR (1) BR9106839A (ko)
CA (1) CA2092615A1 (ko)
DE (1) DE69129988T2 (ko)
DK (1) DK0548228T3 (ko)
ES (1) ES2121786T3 (ko)
FI (1) FI120044B (ko)
WO (1) WO1992005249A1 (ko)

Families Citing this family (671)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK46693D0 (ko) * 1993-04-23 1993-04-23 Novo Nordisk As
US5892013A (en) * 1990-09-13 1999-04-06 Novo Nordisk A/S Lipase variants
EP0599859A1 (en) * 1991-06-25 1994-06-08 Novo Nordisk A/S Mammalian pancreatic lipase and variant thereof
DK88892D0 (da) * 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
SK79595A3 (en) * 1992-12-18 1995-11-08 Unilever Nv Method of production of modified cutinases, dna vector and host
JPH08504589A (ja) * 1992-12-23 1996-05-21 ユニリーバー・ナームローゼ・ベンノートシヤープ 改変クチナーゼ、ｄｎａ、ベクター及び宿主
AU7807394A (en) * 1993-10-04 1995-05-01 Novo Nordisk A/S An enzyme preparation comprising a modified enzyme
WO1995022615A1 (en) * 1994-02-22 1995-08-24 Novo Nordisk A/S A method of preparing a variant of a lipolytic enzyme
AU2884595A (en) * 1994-06-20 1996-01-15 Unilever Plc Modified pseudomonas lipases and their use
FR2722798B1 (fr) * 1994-07-25 1996-09-13 Toulouse Inst Nat Polytech 1procede de production d'acides gras2plantes oleagineuses
US5935271A (en) * 1994-10-13 1999-08-10 Procter & Gamble Company Laundry detergent compositions containing lipolytic enzyme and amines
WO1997000929A1 (en) * 1994-10-13 1997-01-09 The Procter & Gamble Company Detergent compositions containing amines and anionic surfactants
MX9703716A (es) * 1994-11-18 1997-08-30 Procter & Gamble Composiciones detergentes que contienen enzimas lipoliticas especificas.
JPH10509203A (ja) * 1994-11-18 1998-09-08 ザ、プロクター、エンド、ギャンブル、カンパニー リパーゼ及びプロテアーゼを含有した洗剤組成物
GB2297979A (en) * 1995-02-15 1996-08-21 Procter & Gamble Detergent compositions containing a lipase enzyme
BR9607920A (pt) * 1995-03-23 1998-06-09 Astra Ab Molécula de dna vetor de expressão replicável células hospedeiras do gênero pichia e processo para a produção de um polipeptídeo que é uma bssl humana
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
ATE282087T1 (de) * 1995-07-14 2004-11-15 Novozymes As Modifiziertes enzym mit lipolytischer aktivität
US6495357B1 (en) 1995-07-14 2002-12-17 Novozyme A/S Lipolytic enzymes
EP0851913B1 (en) * 1995-08-11 2004-05-19 Novozymes A/S Novel lipolytic enzymes
DK0854933T3 (da) * 1995-09-07 2003-07-21 Novozymes As Fagfremvisning for detergentenzym aktivitet
EP0873387A1 (en) * 1995-09-29 1998-10-28 The Procter & Gamble Company Liquid laundry detergents containing selected quaternary ammonium compounds
JPH11500180A (ja) * 1995-11-17 1999-01-06 ザ、プロクター、エンド、ギャンブル、カンパニー 脂肪分解酵素と選ばれた第四アンモニウム化合物とを含有する洗濯洗剤組成物
EP0866853B1 (en) * 1995-12-07 2004-03-03 Diversa Corporation Method of screening for enzyme activity
AU5861896A (en) * 1996-05-15 1997-12-05 Procter & Gamble Company, The Detergent compositions comprising specific lipolytic enzyme and alkyl poly glucoside surfactant
CA2254781A1 (en) * 1996-05-15 1997-11-20 The Procter & Gamble Company Detergent compositions comprising specific lipolytic enzyme and a specific surfactant system
CA2254919A1 (en) * 1996-05-15 1997-11-20 The Procter & Gamble Company Detergent compositions comprising specific lipolytic enzyme and a soil release polymer
EP0912684A1 (en) * 1996-05-15 1999-05-06 The Procter & Gamble Company Detergent compositions comprising specific lipolytic enzyme and zeolite map
CA2254942A1 (en) * 1996-05-15 1997-11-20 Andre Cesar Baeck Detergent compositions comprising lipolytic enzymes
AU3247699A (en) 1998-02-17 1999-09-06 Novo Nordisk A/S Lipase variant
US6156552A (en) * 1998-02-18 2000-12-05 Novo Nordisk A/S Lipase variants
EP1058724B1 (en) 1998-02-27 2010-12-01 Novozymes A/S Maltogenic alpha-amylase variants
DE69904941T3 (de) 1998-07-21 2008-01-31 Danisco A/S Lebensmittel
AU6188599A (en) 1998-10-26 2000-05-15 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
EP2290059B1 (en) 1998-11-27 2015-11-25 Novozymes A/S Lipolytic enzyme variants
US7312062B2 (en) 1998-11-27 2007-12-25 Novozymes A/S Lipolytic enzyme variants
DK1131416T3 (da) * 1998-11-27 2009-10-26 Novozymes As Lipolytiske enzymvarianter
DE69943346D1 (de) 1998-12-18 2011-05-19 Novozymes As Subtilase Enzyme der I-S1- und I-S2-Untergruppen mit einem zusätzlichen Aminosäurerest in einer aktiven Schleifenregion
EP1194572A2 (en) 1999-03-22 2002-04-10 Novozymes Biotech, Inc. Promoter sequences derived from fusarium venenatum and uses thereof
CA2366843A1 (en) 1999-03-31 2000-10-12 Jesper Vind Lipase variant
WO2000060060A2 (en) 1999-03-31 2000-10-12 Novozymes A/S Polypeptides having alkaline alpha-amylase activity and nucleic acids encoding same
JP4750284B2 (ja) 1999-03-31 2011-08-17 ノボザイムス アクティーゼルスカブ アルカリα−アミラーゼ活性を有するポリペプチド及びそれらをコードする核酸
KR20010108379A (ko) 1999-03-31 2001-12-07 피아 스타르 리파제 변이체
ATE407201T1 (de) 1999-05-20 2008-09-15 Novozymes As Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 126 und 127
ATE408678T1 (de) 1999-05-20 2008-10-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 129 und 130
EP1183342B2 (en) 1999-05-20 2012-06-13 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 128 and 129
DE60040282D1 (de) 1999-05-20 2008-10-30 Novozymes As SUBTILASE ENZYME DER I-S1 UND I-S2 UNTERGRUPPEN MIT MINDESTENS EINER ZUSäTZLICHEN AMINOSäURE ZWISCHEN POSITION 132 UND 133
DE60039693D1 (de) 1999-05-20 2008-09-11 Novozymes As Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 125 und 126
WO2000071689A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 127 and 128
AU5060900A (en) 1999-06-02 2000-12-28 Novozymes A/S Chemically modified lipolytic enzyme
EP2336331A1 (en) 1999-08-31 2011-06-22 Novozymes A/S Novel proteases and variants thereof
EP1248736A1 (en) 1999-09-22 2002-10-16 The Procter & Gamble Company Hand-held liquid container
US6677139B1 (en) 1999-12-23 2004-01-13 Genecor International, Inc. Methods for production of proteins in host cells
US6350599B1 (en) 2000-01-12 2002-02-26 Novozymes A/S Pullulanase variants and methods for preparing such variants with predetermined properties
WO2001083761A1 (en) 2000-04-28 2001-11-08 Novozymes A/S Laccase mutants
DK1307547T3 (da) 2000-07-28 2006-03-20 Henkel Kgaa Hidtil ukendt amylolytisk enzym fra Bacillus sp. A 7-7 (DSM 12368) samt vaske- og rengöringsmidler med dette hidtil ukendte amylolytiske enzym
CA2419896C (en) 2000-08-21 2014-12-09 Novozymes A/S Subtilase enzymes
EP1975229A3 (en) 2000-10-13 2009-03-18 Novozymes A/S Alpha-amylase variant with altered properties
CN101538563A (zh) 2000-10-13 2009-09-23 诺维信公司 枯草杆菌酶变体
DK1352057T3 (da) 2001-01-10 2009-07-20 Novozymes As Upolytisk enzymvariant
EP1360278B1 (en) 2001-02-07 2009-09-23 Novozymes A/S Lipase variants
DE60234523D1 (de) 2001-05-15 2010-01-07 Novozymes As Alpha-amylasevariante mit veränderten eigenschaften
BR0209154A (pt) 2001-05-18 2004-07-20 Danisco Processo de preparação de uma massa com uma enzima
EP2298868B1 (en) 2001-06-26 2015-01-07 Novozymes A/S Polypeptides having cellobiohydrolase I activity and polynucleotides encoding same
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
US7153820B2 (en) 2001-08-13 2006-12-26 Ecolab Inc. Solid detergent composition and method for solidifying a detergent composition
WO2003035878A2 (de) * 2001-10-22 2003-05-01 Basf Aktiengesellschaft Lipase-varianten
US20050255544A1 (en) 2002-01-16 2005-11-17 Novozymes A/S Lipolytic enzyme variants and method for their production
AU2003214037A1 (en) 2002-03-27 2003-10-08 Novozymes A/S Granules with filamentous coatings
US20060127974A1 (en) 2002-07-01 2006-06-15 Novozymes A/S Mpg added to fermentation
EP2302046B1 (en) 2002-10-01 2012-01-04 Novozymes A/S Family GH 61 polypeptides
TWI319007B (en) 2002-11-06 2010-01-01 Novozymes As Subtilase variants
EP1578964B2 (en) 2002-12-20 2013-09-04 Novozymes A/S Polypeptides having cellobiohydrolase ii activity and polynucleotides encoding same
DE602004030000D1 (de) 2003-01-17 2010-12-23 Danisco Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
WO2004067739A2 (en) 2003-01-27 2004-08-12 Novozymes A/S Stabilization of granules
WO2004074419A2 (en) 2003-02-18 2004-09-02 Novozymes A/S Detergent compositions
US7413888B2 (en) 2003-05-02 2008-08-19 Novozymes, Inc. Variants of beta-glucosidases
AU2004252572B2 (en) 2003-06-25 2011-09-08 Novozymes A/S Polypeptides having alpha-amylase activity and polypeptides encoding same
EP2377931B1 (en) 2003-08-25 2013-05-08 Novozymes Inc. Variants of glycoside hydrolases
US7892808B2 (en) 2003-10-10 2011-02-22 Norozymes A/S Protease variants
WO2005040372A1 (en) 2003-10-23 2005-05-06 Novozymes A/S Protease with improved stability in detergents
WO2005047499A1 (en) 2003-10-28 2005-05-26 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US7985569B2 (en) 2003-11-19 2011-07-26 Danisco Us Inc. Cellulomonas 69B4 serine protease variants
CA2546451A1 (en) 2003-11-19 2005-06-09 Genencor International, Inc. Serine proteases, nucleic acids encoding serine enzymes and vectors and host cells incorporating same
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
US7906307B2 (en) 2003-12-24 2011-03-15 Danisco A/S Variant lipid acyltransferases and methods of making
WO2005066339A2 (en) 2004-01-06 2005-07-21 Novozymes A/S Polypeptides of alicyclobacillus sp.
CN1980953B (zh) 2004-01-30 2014-12-24 诺维信股份有限公司 具有分解纤维增强活性的多肽及其编码多核苷酸
US20070281332A1 (en) 2004-02-13 2007-12-06 Allan Svendsen Protease Variants
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
US7148404B2 (en) 2004-05-04 2006-12-12 Novozymes A/S Antimicrobial polypeptides
AU2005254611B2 (en) 2004-06-21 2010-09-23 Novozymes A/S Proteases
ES2554635T3 (es) 2004-07-05 2015-12-22 Novozymes A/S Variantes de alfa-amilasa con propiedades alteradas
BRPI0513438A2 (pt) 2004-07-16 2011-01-04 Danisco método enzimático para degomagem de óleo
DK2258836T3 (en) 2004-09-10 2016-07-25 Novozymes North America Inc Methods for the prevention, elimination, reduction or destruction of biofilms
WO2006032279A1 (en) 2004-09-21 2006-03-30 Novozymes A/S Subtilases
EP1794295B1 (en) 2004-09-21 2011-11-16 Novozymes A/S Subtilases
US7816115B2 (en) 2004-09-21 2010-10-19 Novozymes A/S Subtilases
CN102212510A (zh) 2004-09-30 2011-10-12 诺维信股份有限公司 具有脂肪酶活性的多肽和编码其的多核苷酸
EP1700907A1 (en) 2005-03-11 2006-09-13 Unilever N.V. Liquid bleaching composition
EP1700904A1 (en) 2005-03-11 2006-09-13 Unilever N.V. Liquid detergent composition
BRPI0610031A2 (pt) 2005-04-27 2010-05-18 Novozymes Inc polipeptìdeo isolado, polinucleotìdeo isolado, construção de ácido nucleico, célula hospedeira recombinante, métodos para produzir o polipeptìdeo e para produzir um mutante de uma célula precursora, célula mutante, métodos para produzir uma proteìna, e para produzir um polinucleotìdeo, polinucleotìdeo, mutante, composição detergente, e, método para degradar biomassa contendo celulose e hemi-celulose
EP2385111B1 (en) 2005-07-08 2016-09-07 Novozymes A/S Subtilase variants
ATE530642T1 (de) 2005-08-16 2011-11-15 Novozymes As Subtilasen
US8119387B2 (en) 2005-08-16 2012-02-21 Novozymes A/S Polypeptides of strain Bacillus sp. P203
ES2415872T3 (es) 2005-08-19 2013-07-29 The Procter & Gamble Company Composición detergente para lavado de ropa, sólida que comprende un tensioactivo detersivo aniónico y una tecnología de potenciación del calcio
WO2007036235A1 (en) 2005-09-30 2007-04-05 Novozymes A/S Immobilization of enzymes
EP2385110A3 (en) 2005-09-30 2011-11-16 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
AR059157A1 (es) 2006-01-23 2008-03-12 Procter & Gamble Composiciones detergentes
DK2371948T5 (da) * 2006-01-23 2017-07-24 Novozymes As Lipasevarianter
WO2007087242A2 (en) 2006-01-23 2007-08-02 The Procter & Gamble Company A composition comprising a lipase and a bleach catalyst
WO2007098756A1 (en) 2006-03-02 2007-09-07 Novozymes A/S High capacity encapsulation process
EP1998793A1 (en) 2006-03-22 2008-12-10 Novozymes A/S Use of polypeptides having antimicrobial activity
WO2007113241A1 (en) 2006-03-31 2007-10-11 Novozymes A/S A stabilized liquid enzyme composition
BRPI0709978A2 (pt) 2006-04-14 2011-08-02 Genencor Int tratamento em etapa única de produtos têxteis
WO2008006781A2 (en) 2006-07-14 2008-01-17 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
ES2538360T3 (es) 2006-07-21 2015-06-19 Novozymes, Inc. Métodos para aumentar la secreción de polipéptidos que tienen actividad biológica
CN103122327B (zh) 2006-08-11 2015-11-18 诺维信生物股份有限公司 细菌培养物和包含细菌培养物的组合物
DK2074205T4 (en) 2006-10-06 2017-02-06 Novozymes As CELLULOTIC ENZYME COMPOSITIONS AND APPLICATIONS THEREOF
CN101743308B (zh) * 2006-12-21 2015-09-16 诺维信公司 用于药物用途的脂肪酶变体
US8097444B2 (en) 2006-12-21 2012-01-17 Danisco Us Inc. Compositions and uses for an alpha-amylase polypeptide of bacillus species 195
AU2007344910B2 (en) 2007-01-25 2013-03-28 Dupont Nutrition Biosciences Aps Production of a lipid acyltransferase from transformed Bacillus licheniformis cells
US8093200B2 (en) 2007-02-15 2012-01-10 Ecolab Usa Inc. Fast dissolving solid detergent
EP2126089A2 (en) 2007-03-09 2009-12-02 Danisco US, INC., Genencor Division Alkaliphilic bacillus species a-amylase variants, compositions comprising a-amylase variants, and methods of use
CN101641439B (zh) 2007-03-09 2016-05-25 诺维信公司 天冬酰胺酶
AU2008231038B2 (en) 2007-03-23 2013-07-11 Novozymes Biologicals, Inc. Preventing and reducing biofilm formation and planktonic proliferation
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
WO2008122640A2 (en) 2007-04-09 2008-10-16 Novozymes A/S An enzymatic treatment of skin and hide degreasing
AU2008313267B2 (en) 2007-10-18 2013-09-19 Ecolab Inc. Pressed, waxy, solid cleaning compositions and methods of making them
US7618801B2 (en) 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
DK2215202T3 (da) 2007-11-05 2017-11-27 Danisco Us Inc VARIANTER AF BACILLUS sp. TS-23 ALPHA-AMYLASE MED ÆNDREDE EGENSKABER
EP2215110A2 (en) 2007-11-05 2010-08-11 Danisco US, Inc., Genencor Division Alpha-amylase variants with altered properties
US20100267067A1 (en) 2007-11-29 2010-10-21 Novozymes A/S Synthase Inhibitor Screening Method
US7879790B2 (en) 2008-01-22 2011-02-01 Stepan Company Mixed salts of sulfonated estolides and other derivatives of fatty acids, and methods of making them
US7998920B2 (en) 2008-01-22 2011-08-16 Stepan Company Sulfonated estolide compositions containing magnesium sulfate and processes employing them
US7666828B2 (en) 2008-01-22 2010-02-23 Stepan Company Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them
AU2009212526A1 (en) 2008-02-04 2009-08-13 Danisco Us Inc. TS23 alpha-amylase variants with altered properties
MX2010009077A (es) * 2008-02-29 2010-09-24 Novozymes As Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma.
JP2011513539A (ja) * 2008-02-29 2011-04-28 ザ プロクター アンド ギャンブル カンパニー リパーゼを含む洗剤組成物
WO2009134670A2 (en) 2008-04-30 2009-11-05 Danisco Us Inc., Genencor Division New chimeric alpha-amylase variants
CA2726274C (en) 2008-06-06 2018-11-20 Danisco Us Inc. Variant alpha-amylases from bacillus subtilis and methods of use, thereof
MX2010013122A (es) 2008-06-06 2011-01-21 Danisco Inc Composicion de enzima de sacarificacion y metodo de sacarificacion de la misma.
WO2009149271A2 (en) 2008-06-06 2009-12-10 Danisco Us Inc. Production of glucose from starch using alpha-amylases from bacillus subtilis
CA2726265A1 (en) 2008-06-06 2009-12-10 Danisco Us Inc. Geobacillus stearothermophilus alpha-amylase (amys) variants with improved properties
GB0810881D0 (en) 2008-06-16 2008-07-23 Unilever Plc Improvements relating to fabric cleaning
EP2149786A1 (en) 2008-08-01 2010-02-03 Unilever PLC Improvements relating to detergent analysis
DE212009000119U1 (de) 2008-09-12 2011-12-30 Unilever N.V. Spender und Vorbehandlungsmittel für viskose Flüssigkeiten
MX2011003178A (es) 2008-09-25 2011-04-21 Danisco Inc Mezclas de alfa-amilasa y metodos para usar esas mezclas.
ES2526867T3 (es) 2008-11-20 2015-01-16 Novozymes Inc. Polipéptido que tiene actividad potenciadora amilolítica y polinucleótidos que codifican el mismo
WO2010065830A1 (en) 2008-12-04 2010-06-10 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
EP2202290A1 (en) 2008-12-23 2010-06-30 Unilever PLC A flowable laundry composition and packaging therefor
US7884064B2 (en) 2009-01-21 2011-02-08 Stepan Company Light duty liquid detergent compositions of sulfonated estolides and other derivatives of fatty acids
BRPI0924129B1 (pt) 2009-01-21 2019-09-17 Stepan Company Composição agrícola de estolides sulfonados e outros derivados de ácidos graxos
US8058223B2 (en) 2009-01-21 2011-11-15 Stepan Company Automatic or machine dishwashing compositions of sulfonated estolides and other derivatives of fatty acids and uses thereof
US8119588B2 (en) 2009-01-21 2012-02-21 Stepan Company Hard surface cleaner compositions of sulfonated estolides and other derivatives of fatty acids and uses thereof
US8124577B2 (en) 2009-01-21 2012-02-28 Stepan Company Personal care compositions of sulfonated estolides and other derivatives of fatty acids and uses thereof
EP2213723A1 (en) 2009-01-30 2010-08-04 Novozymes A/S Isomaltose for fungus fermentation
WO2010097436A1 (en) 2009-02-27 2010-09-02 Novozymes A/S Mutant cells having reduced expression of metallopeptidase, suitable for recombinant polypeptide production
BRPI1009263A2 (pt) 2009-03-10 2015-10-06 Danisco Us Inc alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas.
US8153574B2 (en) 2009-03-18 2012-04-10 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes
US8293697B2 (en) 2009-03-18 2012-10-23 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives
CN102378813B (zh) 2009-04-01 2014-05-14 丹尼斯科美国公司 包含具有改变的性质的α-淀粉酶变体的组合物和方法
BRPI1012590A2 (pt) 2009-04-08 2015-09-22 Danisco Us Inc Genencor Div alfa-amilases relacionadas à cepa wdg-195 de halomonas e métodos de uso das mesmas
WO2010127919A1 (en) 2009-05-05 2010-11-11 Unilever Plc Shading composition
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
EP2277860B1 (en) 2009-07-22 2015-08-19 Stepan Company Compositions comprising sulfonated estolides and alkyl ester sulfonates, methods of making them, and compositions and processes employing them
EP3269804B1 (en) 2009-09-17 2020-11-11 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2775045A1 (en) 2009-09-25 2011-03-31 Novozymes A/S Subtilase variants for use in detergent and cleaning compositions
EP2480663B1 (en) 2009-09-25 2017-11-15 Novozymes A/S Use of variants of the serin protease subtilisin
WO2011041397A1 (en) 2009-09-29 2011-04-07 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN102695720B (zh) 2009-09-30 2018-02-16 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
BR112012007390A2 (pt) 2009-09-30 2015-09-15 Novozymes As polipeptídeo isolado tendo atividade intensificadora celulolítica, polinucleotídeo isolado, métodos para produzir o polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degragar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada com um polinucleotídeo, molécula inibidora de filamento duplo, e, composição detergente
MX2012004091A (es) 2009-10-08 2012-04-20 Unilever Nv Composicion matizante.
WO2011045195A1 (en) 2009-10-13 2011-04-21 Unilever Plc Dye polymers
US20120276602A1 (en) 2009-10-21 2012-11-01 Novozymes A/S Method For Treatment of Oil
WO2011047987A1 (en) 2009-10-23 2011-04-28 Unilever Plc Dye polymers
IN2012DN02731A (ko) 2009-10-23 2015-09-11 Danisco Us Inc
CN102639687A (zh) 2009-11-13 2012-08-15 诺维信公司 酿造方法
EP2501792A2 (en) 2009-12-29 2012-09-26 Novozymes A/S Gh61 polypeptides having detergency enhancing effect
CN102753672B (zh) 2010-01-07 2014-11-12 荷兰联合利华有限公司 天然调色剂
EP2343310A1 (en) 2010-01-08 2011-07-13 Novozymes A/S Serine hydrolase formulation
CN102844324B (zh) 2010-01-22 2015-10-07 杜邦营养生物科学有限公司 制备氨基取代的糖脂化合物的方法
ZA201205562B (en) 2010-02-09 2013-09-25 Unilever Plc Dye polymers
ES2530522T3 (es) 2010-02-12 2015-03-03 Unilever Nv Composición de tratamiento para el lavado de ropa, que comprende colorantes de matizado bis-azoicos
US8859259B2 (en) 2010-02-14 2014-10-14 Ls9, Inc. Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols
WO2011102933A1 (en) 2010-02-18 2011-08-25 Danisco Us Inc. Amylase from nesterenkonia and methods of use, thereof
MX2012009705A (es) 2010-02-25 2012-12-17 Novozymes As Variantes de lisozima y polinucleotidos que codifican la misma.
MX349735B (es) 2010-04-26 2017-08-10 Novozymes As Granulos de enzima.
CN102892875A (zh) 2010-04-29 2013-01-23 荷兰联合利华有限公司 双杂环偶氮染料
DE102010028951A1 (de) 2010-05-12 2011-11-17 Henkel Ag & Co. Kgaa Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Lipase
WO2012010406A1 (en) 2010-07-22 2012-01-26 Unilever Plc Combinations of rhamnolipids and enzymes for improved cleaning
KR20130102536A (ko) 2010-08-30 2013-09-17 노보자임스 에이/에스 농축된 불림 세탁
CN103492545A (zh) 2010-08-30 2014-01-01 诺维信公司 两次浸泡洗涤
US20130266554A1 (en) 2010-09-16 2013-10-10 Novozymes A/S Lysozymes
GB201015672D0 (en) 2010-09-20 2010-10-27 Unilever Plc Improvements relating to fabric treatment compositions comprising targeted benefit agents
US10246691B2 (en) 2010-09-30 2019-04-02 Novozymes, Inc. Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
BR112013007699B1 (pt) 2010-09-30 2021-12-21 Novozymes, Inc. Variante, polinucleotídeo isolado, célula hospedeira microbiana recombinante, métodos para produzir uma variante, para degradar um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, e, composição enzimática, formulação do caldo completo ou composição de cultura de células
BR112013009133B1 (pt) 2010-10-14 2021-06-15 Unilever Ip Holdings B.V. Partícula de detergente revestida e pluralidade de partículas de detergente revestidas
MX340440B (es) 2010-10-14 2016-07-08 Unilever N V * Particula de detergente para lavanderia.
WO2012049034A1 (en) 2010-10-14 2012-04-19 Unilever Plc Packaging and dispensing of detergent compositions
WO2012049055A1 (en) 2010-10-14 2012-04-19 Unilever Plc Transparent packaging of detergent compositions
EP2627751B1 (en) 2010-10-14 2015-06-03 Unilever PLC Top-loading laundry vessel method
AU2011316077B2 (en) 2010-10-14 2014-01-23 Unilever Plc Packaged particulate detergent composition
EP2441825A1 (en) 2010-10-14 2012-04-18 Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House Process for preparing laundry detergent particles
EP2441820A1 (en) 2010-10-14 2012-04-18 Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House Laundry detergent particles
EP2627754B1 (en) 2010-10-14 2016-11-30 Unilever PLC Laundry detergent particles
ES2591003T3 (es) 2010-10-14 2016-11-24 Unilever N.V. Paquete que comprende una composición para lavado de ropa y procedimiento para lavar que utiliza dicho paquete
IN2013MN00626A (ko) 2010-10-14 2015-06-12 Unilever Plc
IN2013MN00624A (ko) 2010-10-14 2015-06-12 Unilever Plc
WO2012048950A1 (en) 2010-10-14 2012-04-19 Unilever Plc Laundry detergent particles
EP2441822A1 (en) 2010-10-14 2012-04-18 Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House Laundry detergent particles
WO2012048910A1 (en) 2010-10-14 2012-04-19 Unilever Plc Packaged particulate detergent composition
BR112013009129B1 (pt) 2010-10-14 2020-10-13 Unilever N.V. partícula de detergente revestida
PL2627748T3 (pl) 2010-10-14 2015-04-30 Unilever Nv Rozdrobnione detergentowe kompozycje zawierające fluorescer
WO2012049032A1 (en) 2010-10-14 2012-04-19 Unilever Plc Refill and refillable packages of concentrated particulate detergent compositions
BR112013009130B1 (pt) 2010-10-14 2021-10-26 Unilever Ip Holdings B.V. Partícula de detergente revestida e pluralidade de partícula de detergente revestida
BR112013009456B1 (pt) 2010-10-22 2021-11-30 Unilever Ip Holdings B.V. Composição líquida detergente aquosa estruturada e processo para fabricar um líquido detergente aquoso estruturado
CN103168095A (zh) 2010-11-01 2013-06-19 荷兰联合利华有限公司 具有遮蔽染料和脂肪酶的洗涤剂组合物
BR112013010129A2 (pt) 2010-11-18 2016-07-05 Novozymes Inc polipeptídeo gh61 quimérico isolado, polinucleotídeo isolado, célula hospedeira, métodos para produzir um polipeptídeo gh61 quimérico, para degradas ou converter um material celulóstico, para sintetizar um produto de fermentação, para fermentar um material celulósico e para limpar ou lavar uma superfície dura ou roupa para lavar, planta transgênica, parte da planta ou célula de planta, uso do polipeptídeo gh61 quimérico, composição detergente, e, formulação de caldo ou composição de cultura de células completas
WO2012098046A1 (en) 2011-01-17 2012-07-26 Unilever Plc Dye polymer for laundry treatment
EP2670839B1 (en) 2011-01-31 2017-11-08 Novozymes A/S Use of browned glucose for the fermentative production of thaxtomin.
AU2012213597B2 (en) 2011-01-31 2014-08-28 Unilever Plc Alkaline liquid detergent compositions
CN107815817A (zh) 2011-02-15 2018-03-20 诺维信生物股份有限公司 清洁机器及清洁方法中的气味的减轻
CN103476916A (zh) 2011-02-16 2013-12-25 诺维信公司 包含m7或m35金属蛋白酶的去污剂组合物
WO2012110562A2 (en) 2011-02-16 2012-08-23 Novozymes A/S Detergent compositions comprising metalloproteases
WO2012110563A1 (en) 2011-02-16 2012-08-23 Novozymes A/S Detergent compositions comprising metalloproteases
MX2013007997A (es) 2011-02-23 2013-08-21 Novozymes Inc Polipeptidos que tienen actividad de incremento celulolitico y polinucleotidos que codifican para los mismos.
WO2012119859A1 (en) 2011-03-10 2012-09-13 Unilever Plc Dye polymer
WO2012130492A1 (en) 2011-03-25 2012-10-04 Unilever Plc Dye polymer
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
ES2421162T3 (es) 2011-04-04 2013-08-29 Unilever Nv Procedimiento de lavado de telas
EP2702162B1 (en) 2011-04-29 2020-02-26 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
EP2522714A1 (en) 2011-05-13 2012-11-14 Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House Aqueous concentrated laundry detergent compositions
EP2522715A1 (en) 2011-05-13 2012-11-14 Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House Aqueous concentrated laundry detergent compositions
CA2856820C (en) 2011-05-20 2019-10-29 Ecolab Usa Inc. Acid formulations for use in a system for warewashing
EP2710105A4 (en) 2011-05-20 2015-03-25 Ecolab Usa Inc PHOSPHATE-FREE DETERGENTS AND NON-PHOSPHORIC ACIDS IN AN ALTERNATIVELY ALKALINE / ACID SYSTEM FOR CLEANING MANUFACTURED OBJECTS
WO2012159778A1 (en) 2011-05-26 2012-11-29 Unilever Plc Liquid laundry composition
EP2714985B1 (en) 2011-06-01 2018-02-28 Unilever PLC Liquid detergent composition containing dye polymer
US10829721B2 (en) 2011-06-20 2020-11-10 Novozymes A/S Particulate composition
JP6126086B2 (ja) 2011-06-24 2017-05-10 ノボザイムス アクティーゼルスカブ プロテアーゼ活性を有するポリペプチドおよびこれをコードするポリヌクレオチド
US9434932B2 (en) 2011-06-30 2016-09-06 Novozymes A/S Alpha-amylase variants
EP3543333B1 (en) 2011-06-30 2022-01-05 Novozymes A/S Method for screening alpha-amylases
EP2726590B1 (en) 2011-07-01 2017-10-18 Novozymes A/S Liquid detergent composition
CN103649292B (zh) 2011-07-01 2017-11-28 诺维信公司 稳定化的枯草杆菌蛋白酶组合物
CN107523441A (zh) 2011-07-12 2017-12-29 诺维信公司 储存稳定的酶颗粒
ES2550051T3 (es) 2011-07-21 2015-11-04 Unilever N.V. Composición líquida para el lavado de ropa
BR112013032861A2 (pt) 2011-07-22 2017-01-24 Novozymes North America Inc métodos para aumentar a atividade da enzima celulolítica durante a hidrólise do material celulósico, para hidrolisar um material celulósico pré-tratado, para a produção de um produto da fermentação, e para a fermentação de um material celulósico pré-tratado
US9000138B2 (en) 2011-08-15 2015-04-07 Novozymes A/S Expression constructs comprising a Terebella lapidaria nucleic acid encoding a cellulase, host cells, and methods of making the cellulase
CN103764822B (zh) 2011-08-19 2016-11-23 诺维信公司 具有蛋白酶活性的多肽
US20140227738A1 (en) 2011-09-22 2014-08-14 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
RU2014121491A (ru) 2011-10-28 2015-12-10 ДАНИСКО ЮЭс ИНК. Варианты вариантной альфа-амилазы, образующей мальтогексаозу
DK3219794T3 (da) 2011-11-21 2019-12-16 Novozymes Inc GH61-polypeptidvarianter og polynukleotider, som koder for dem
CN103958657A (zh) 2011-11-25 2014-07-30 诺维信公司 枯草杆菌酶变体以及编码该枯草杆菌酶变体的多核苷酸
US9701952B2 (en) 2011-11-25 2017-07-11 Novozymes A/S Polypeptides having lysozyme activity and polynucleotides encoding same
JP6014163B2 (ja) 2011-12-13 2016-10-25 エコラボ ユーエスエー インコーポレイティド 濃縮物品洗浄組成物及び方法
WO2013087027A1 (en) 2011-12-16 2013-06-20 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
EP2809762B1 (en) 2011-12-20 2016-03-23 Unilever Plc. Liquid detergents comprising lipase and bleach catalyst
EP2607468A1 (en) 2011-12-20 2013-06-26 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
WO2013092635A1 (en) 2011-12-20 2013-06-27 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2013092052A1 (en) 2011-12-20 2013-06-27 Unilever Plc Isotropic liquid detergents comprising soil release polymer
BR112014015421A2 (pt) 2011-12-22 2019-09-24 Danisco Us Inc alfa-amilases variantes e métodos de uso das mesmas
WO2013096653A1 (en) 2011-12-22 2013-06-27 Danisco Us Inc. Compositions and methods comprising a lipolytic enzyme variant
MX358963B (es) 2011-12-28 2018-09-11 Novozymes As Polipeptidos con actividad proteasa.
MX2014007612A (es) 2011-12-29 2014-09-15 Novozymes As Composiciones detergentes con variantes de lipasa.
CN104350149A (zh) 2012-01-26 2015-02-11 诺维信公司 具有蛋白酶活性的多肽在动物饲料和洗涤剂中的用途
JP2015512613A (ja) 2012-02-03 2015-04-30 ノボザイムス アクティーゼルスカブ リパーゼ変異体およびこれをコードするポリヌクレオチド
US10093911B2 (en) 2012-02-17 2018-10-09 Novozymes A/S Subtilisin variants and polynucleotides encoding same
EP2628785B1 (en) 2012-02-17 2016-05-18 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
CN104704102A (zh) 2012-03-07 2015-06-10 诺维信公司 洗涤剂组合物和洗涤剂组合物中光增亮剂的取代
EP2639291A1 (en) 2012-03-13 2013-09-18 Unilever PLC Packaged particulate detergent composition
US10087401B2 (en) 2012-03-16 2018-10-02 Monosol, Llc Water soluble compositions incorporating enzymes, and method of making same
WO2013139702A1 (en) 2012-03-21 2013-09-26 Unilever Plc Laundry detergent particles
EP2831215B1 (en) 2012-03-29 2018-08-08 Novozymes A/S Use of enzymes for preparing water soluble films
US9909109B2 (en) 2012-04-02 2018-03-06 Novozymes A/S Lipase variants and polynucleotides encoding same
BR112014021493B1 (pt) 2012-04-03 2021-05-11 Unilever Ip Holdings B.V partícula detergente revestida e formulação detergente embalada
MX2014011547A (es) 2012-04-03 2014-11-14 Unilever Nv Particulas de detergente para lavado de ropa.
WO2013149754A1 (en) 2012-04-03 2013-10-10 Unilever Plc Laundry detergent particle
WO2013149752A1 (en) 2012-04-03 2013-10-10 Unilever Plc Laundry detergent particles
US9394092B2 (en) 2012-04-16 2016-07-19 Monosol, Llc Powdered pouch and method of making same
EP2841547B1 (en) 2012-04-23 2016-07-13 Unilever PLC Structured aqueous liquid detergent
CN104245926B (zh) 2012-04-27 2021-05-07 诺维信股份有限公司 Gh61多肽变体以及编码其的多核苷酸
AR090971A1 (es) 2012-05-07 2014-12-17 Novozymes As Polipeptidos que tienen actividad de degradacion de xantano y polinucleotidos que los codifican
US8945889B2 (en) 2012-05-11 2015-02-03 Danisco Us Inc. Method of using alpha-amylase from Aspergillus clavatus for saccharification
MX2014013727A (es) 2012-05-16 2015-02-10 Novozymes As Composiciones que comprenden lipasa y metodos de utilizacion de estas.
DK2825643T3 (da) 2012-06-08 2021-11-08 Danisco Us Inc Variant-alfa-amylaser med forbedret aktivitet over for stivelsespolymerer
EP2861749A1 (en) 2012-06-19 2015-04-22 Novozymes Bioag A/S Enzymatic reduction of hydroperoxides
AU2013279440B2 (en) 2012-06-20 2016-10-06 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
US9663804B2 (en) 2012-07-18 2017-05-30 Novozymes A/S Method of treating polyester textile
CA2878988A1 (en) 2012-08-16 2014-02-20 Danisco Us Inc. Method of using alpha-amylase from aspergillus clavatus and pullulanase for saccharification
TR201909592T4 (tr) 2012-08-16 2019-07-22 Novozymes As Tekstili endoglukanazla işlemden geçirmek için usul.
CN104603266B (zh) 2012-08-22 2017-11-10 诺维信公司 来自脂环酸芽孢杆菌属的金属蛋白酶
BR112015003726A2 (pt) 2012-08-22 2019-09-24 Novozymes As composição detergente, uso de uma composição e de um polipeptídeo, e, método para remoção de uma nódoa de uma superfície.
WO2014029819A1 (en) 2012-08-22 2014-02-27 Novozymes A/S Metalloprotease from exiguobacterium
US9745543B2 (en) 2012-09-10 2017-08-29 Ecolab Usa Inc. Stable liquid manual dishwashing compositions containing enzymes
CN104662140B (zh) 2012-09-25 2018-07-31 荷兰联合利华有限公司 洗衣洗涤剂颗粒
CN104797590A (zh) 2012-11-01 2015-07-22 诺维信公司 用于去除dna的方法
EP2922951B1 (en) 2012-11-20 2017-08-23 Danisco US Inc. Amylase with maltogenic properties
TR201910918T4 (tr) 2012-12-07 2019-08-21 Novozymes As Bakterilerin yapışmasının önlenmesi.
EP2931872B1 (en) 2012-12-11 2018-01-17 Danisco US Inc. Trichoderma reesei host cells expressing a glucoamylase from aspergillus fumigatus and methods of use thereof
WO2014090940A1 (en) 2012-12-14 2014-06-19 Novozymes A/S Removal of skin-derived body soils
US9765374B2 (en) 2012-12-14 2017-09-19 Danisco Us Inc Method of using α-amylase from Aspergillus fumigatus and isoamylase for saccharification
WO2014099415A1 (en) 2012-12-20 2014-06-26 Danisco Us Inc. Method of using alpha-amylase from aspergillus terreus and pullulanase for saccharification
DK3354728T3 (da) 2012-12-21 2020-07-27 Danisco Us Inc Alpha-amylase-varianter
MX363360B (es) 2012-12-21 2019-03-21 Novozymes As Polipéptidos que poseen actividad proteasa y polinucleótidos que los codifican.
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
EP2941485B1 (en) 2013-01-03 2018-02-21 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
DK2970930T4 (da) 2013-03-11 2022-03-14 Danisco Us Inc Kombinatoriske alpha-amylasevarianter
US20160024440A1 (en) 2013-03-14 2016-01-28 Novozymes A/S Enzyme and Inhibitor Containing Water-Soluble Films
CN105051174B (zh) 2013-03-21 2018-04-03 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
CN111394202B (zh) 2013-04-23 2022-04-26 诺维信公司 具有稳定的枯草杆菌蛋白酶的液体自动餐具清洗洗涤剂组合物
CN105164244B (zh) 2013-05-03 2019-08-20 诺维信公司 洗涤剂酶的微囊化
RU2020101263A (ru) 2013-05-14 2020-02-17 Новозимс А/С Моющие композиции
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
CN118813589A (zh) 2013-06-06 2024-10-22 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
DE102013210506A1 (de) 2013-06-06 2014-12-11 Henkel Ag & Co. Kgaa Alkoholoxidase mit Aktivität für Glycerol
BR112015031099B1 (pt) 2013-06-12 2023-01-17 Earth Alive Clean Technologies Inc Composição de supressão de poeira, e método para redução ou supressão de poeira em uma estrada não pavimentada
WO2014200657A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces xiamenensis
WO2014200656A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces umbrinus
WO2014200658A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from promicromonospora vindobonensis
US20160130571A1 (en) 2013-06-17 2016-05-12 Danisco Us Inc. Alpha-Amylase from Bacillaceae Family Member
EP3013955A1 (en) 2013-06-27 2016-05-04 Novozymes A/S Subtilase variants and polynucleotides encoding same
FI3013956T3 (fi) 2013-06-27 2023-05-23 Novozymes As Subtilaasivariantteja ja niitä koodittavia polynukleotideja
JP2016523098A (ja) 2013-07-04 2016-08-08 ノボザイムス アクティーゼルスカブ 再付着防止効果を有するポリペプチドおよびそれをコードするポリヌクレオチド
US20160160196A1 (en) 2013-07-09 2016-06-09 Novozymes A/S Polypeptides with Lipase Activity And Polynucleotides Encoding Same
MX371497B (es) 2013-07-19 2020-01-31 Danisco Us Inc Composiciones y metodos que comprenden una variante de enzima lipolitica.
EP2832853A1 (en) 2013-07-29 2015-02-04 Henkel AG&Co. KGAA Detergent composition comprising protease variants
US9926550B2 (en) 2013-07-29 2018-03-27 Novozymes A/S Protease variants and polynucleotides encoding same
US10150957B2 (en) 2013-07-29 2018-12-11 Novozymes A/S Protease variants and polynucleotides encoding same
WO2015049370A1 (en) 2013-10-03 2015-04-09 Novozymes A/S Detergent composition and use of detergent composition
WO2015050723A1 (en) 2013-10-03 2015-04-09 Danisco Us Inc. Alpha-amylases from exiguobacterium, and methods of use, thereof
EP3052622B1 (en) 2013-10-03 2018-09-19 Danisco US Inc. Alpha-amylases from a subset of exiguobacterium, and methods of use, thereof
JP6560214B2 (ja) 2013-11-20 2019-08-14 ダニスコ・ユーエス・インク プロテアーゼ開裂に対する感受性を低減した変異体α−アミラーゼ、及びその使用方法
US10005850B2 (en) 2013-12-16 2018-06-26 E I Du Pont De Nemours And Company Use of poly alpha-1,3-glucan ethers as viscosity modifiers
EP3789407B1 (en) 2013-12-18 2024-07-24 Nutrition & Biosciences USA 4, Inc. Cationic poly alpha-1,3-glucan ethers
WO2015094809A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Chimeric fungal alpha-amylases comprising carbohydrate binding module and the use thereof
EP3453757B1 (en) 2013-12-20 2020-06-17 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
CN105849121B (zh) 2014-01-22 2020-12-29 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
US20150232785A1 (en) 2014-02-14 2015-08-20 E I Du Pont De Nemours And Company Polysaccharides for viscosity modification
US20160348035A1 (en) 2014-03-05 2016-12-01 Novozymes A/S Compositions and Methods for Improving Properties of Non-Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
US20160333292A1 (en) 2014-03-05 2016-11-17 Novozymes A/S Compositions and Methods for Improving Properties of Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
US9695253B2 (en) 2014-03-11 2017-07-04 E I Du Pont De Nemours And Company Oxidized poly alpha-1,3-glucan
EP3117001B1 (en) 2014-03-12 2019-02-20 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015150457A1 (en) 2014-04-01 2015-10-08 Novozymes A/S Polypeptides having alpha amylase activity
EP3722406A1 (en) 2014-04-11 2020-10-14 Novozymes A/S Detergent composition
WO2015158237A1 (en) 2014-04-15 2015-10-22 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
US10683489B2 (en) 2014-05-27 2020-06-16 Novozymes A/S Methods for producing lipases
EP3149178B1 (en) 2014-05-27 2020-07-15 Novozymes A/S Lipase variants and polynucleotides encoding same
JP6726626B2 (ja) 2014-06-09 2020-07-22 ステパン カンパニー 冷水洗浄用洗剤
CN106414729A (zh) 2014-06-12 2017-02-15 诺维信公司 α‑淀粉酶变体以及对其进行编码的多核苷酸
EP3158043B1 (en) 2014-06-19 2021-03-10 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
WO2016001319A1 (en) 2014-07-03 2016-01-07 Novozymes A/S Improved stabilization of non-protease enzyme
CN116240202A (zh) 2014-07-04 2023-06-09 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
EP3739029A1 (en) 2014-07-04 2020-11-18 Novozymes A/S Subtilase variants and polynucleotides encoding same
BR112017005495B1 (pt) 2014-09-18 2021-11-30 Unilever Ip Holdings B.V. Composição de detergente para lavagem de roupas e método doméstico de tratamento de um tecido
WO2016079110A2 (en) 2014-11-19 2016-05-26 Novozymes A/S Use of enzyme for cleaning
US10287562B2 (en) 2014-11-20 2019-05-14 Novoszymes A/S Alicyclobacillus variants and polynucleotides encoding same
EP3227444B1 (en) 2014-12-04 2020-02-12 Novozymes A/S Subtilase variants and polynucleotides encoding same
CA2965231A1 (en) 2014-12-05 2016-06-09 Novozymes A/S Lipase variants and polynucleotides encoding same
PL3399031T3 (pl) 2014-12-15 2020-05-18 Henkel Ag & Co. Kgaa Kompozycja detergentowa zawierająca odmiany subtylazy
EP3233894A1 (en) 2014-12-16 2017-10-25 Novozymes A/S Polypeptides having n-acetyl glucosamine oxidase activity
EP3234093B1 (en) 2014-12-19 2020-05-27 Novozymes A/S Protease variants and polynucleotides encoding same
EP3234123B1 (en) 2014-12-19 2020-06-03 Novozymes A/S Protease variants and polynucleotides encoding same
CN108064306B (zh) 2014-12-23 2022-11-01 营养与生物科学美国4公司 酶促产生的纤维素
EP3242925A2 (en) 2015-01-08 2017-11-15 Stepan Company Cold-water laundry detergents
TR201819563T4 (tr) 2015-01-09 2019-01-21 Unilever Nv Bir boya içeren çamaşır arıtma bileşimi.
CN107207998B (zh) 2015-02-13 2020-04-10 荷兰联合利华有限公司 液体洗衣组合物
WO2016133734A1 (en) 2015-02-18 2016-08-25 E. I. Du Pont De Nemours And Company Soy polysaccharide ethers
WO2016160407A1 (en) 2015-03-31 2016-10-06 Stepan Company Detergents based on alpha-sulfonated fatty ester surfactants
WO2016155993A1 (en) 2015-04-02 2016-10-06 Unilever Plc Composition
WO2016164596A2 (en) 2015-04-07 2016-10-13 Novozymes A/S Methods for selecting enzymes having lipase activity
WO2016162556A1 (en) 2015-04-10 2016-10-13 Novozymes A/S Laundry method, use of dnase and detergent composition
US20180105772A1 (en) 2015-04-10 2018-04-19 Novozymes A/S Detergent composition
EP3298121B1 (en) 2015-05-19 2019-03-20 Novozymes A/S Odor reduction
WO2016196555A1 (en) 2015-06-02 2016-12-08 Stepan Company Cold-water cleaning method
ES2665989T3 (es) 2015-06-04 2018-04-30 The Procter & Gamble Company Composición detergente líquida para lavado de vajillas a mano
ES2670044T3 (es) 2015-06-04 2018-05-29 The Procter & Gamble Company Composición detergente líquida para lavado de vajillas a mano
CN108012543B (zh) 2015-06-16 2022-01-04 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
CN107922095A (zh) 2015-06-17 2018-04-17 诺维信公司 容器
EP3106508B1 (en) 2015-06-18 2019-11-20 Henkel AG & Co. KGaA Detergent composition comprising subtilase variants
US11162089B2 (en) 2015-06-18 2021-11-02 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3317388B1 (en) 2015-06-30 2019-11-13 Novozymes A/S Laundry detergent composition, method for washing and use of composition
CA2987160C (en) 2015-07-01 2022-12-13 Novozymes A/S Methods of reducing odor
EP3950939A3 (en) 2015-07-06 2022-06-08 Novozymes A/S Lipase variants and polynucleotides encoding same
AU2016323412B2 (en) 2015-09-17 2021-04-01 Henkel Ag & Co. Kgaa Detergent compositions comprising polypeptides having xanthan degrading activity
US20180171315A1 (en) 2015-09-17 2018-06-21 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
WO2017060475A2 (en) 2015-10-07 2017-04-13 Novozymes A/S Polypeptides
EP4324919A3 (en) 2015-10-14 2024-05-29 Novozymes A/S Polypeptide variants
EP3362168A1 (en) 2015-10-14 2018-08-22 Novozymes A/S Cleaning of water filtration membranes
WO2017064253A1 (en) 2015-10-14 2017-04-20 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US11028346B2 (en) 2015-10-28 2021-06-08 Novozymes A/S Detergent composition comprising protease and amylase variants
US10844324B2 (en) 2015-11-13 2020-11-24 Dupont Industrial Biosciences Usa, Llc Glucan fiber compositions for use in laundry care and fabric care
WO2017083229A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
WO2017089366A1 (en) 2015-11-24 2017-06-01 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP3384019B1 (en) 2015-12-01 2020-06-24 Novozymes A/S Methods for producing lipases
CN108431220B (zh) 2015-12-07 2022-06-07 诺维信公司 具有β-葡聚糖酶活性的多肽、编码其的多核苷酸及其在清洁和洗涤剂组合物中的用途
WO2017100051A2 (en) 2015-12-07 2017-06-15 Stepan Comapny Cold-water cleaning compositions and methods
CA3005292A1 (en) 2015-12-09 2017-06-15 Basf Se Method of purifying a protein from fermentation solids under desorbing conditions
JP2019500058A (ja) 2015-12-09 2019-01-10 ダニスコ・ユーエス・インク α−アミラーゼ組み合わせ変異体
EP3397061A1 (en) 2015-12-28 2018-11-07 Novozymes BioAG A/S Heat priming of bacterial spores
EP3397761B1 (en) 2015-12-30 2022-11-09 Novozymes A/S Enzyme variants and polynucleotides encoding the same
TR201808208T4 (tr) 2016-01-07 2018-07-23 Unilever Nv Acı parçacık.
WO2017121714A1 (en) 2016-01-15 2017-07-20 Unilever Plc Dye
WO2017129754A1 (en) 2016-01-29 2017-08-03 Novozymes A/S Beta-glucanase variants and polynucleotides encoding same
WO2017133879A1 (en) 2016-02-04 2017-08-10 Unilever Plc Detergent liquid
WO2017140391A1 (en) 2016-02-17 2017-08-24 Unilever Plc Whitening composition
EP3417040B1 (en) 2016-02-17 2019-09-04 Unilever PLC Whitening composition
EP3433346B1 (en) 2016-03-21 2020-12-30 Unilever PLC Laundry detergent composition
CN109072133B (zh) 2016-03-23 2021-06-15 诺维信公司 具有dna酶活性的多肽用于处理织物的用途
WO2017173190A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
WO2017173324A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
BR112018070468B1 (pt) 2016-04-08 2022-07-12 Unilever Ip Holdings B.V Composição de detergente líquida aquosa para lavagem de roupas e método doméstico de tratamento de um tecido
CN114480035B (zh) 2016-04-08 2024-10-11 诺维信公司 洗涤剂组合物及其用途
CN109312271A (zh) 2016-04-29 2019-02-05 诺维信公司 洗涤剂组合物及其用途
CN109415421B (zh) 2016-05-03 2023-02-28 诺维信公司 α-淀粉酶变体以及编码它们的多核苷酸
JP6985295B2 (ja) 2016-05-09 2021-12-22 ノボザイムス アクティーゼルスカブ 向上した性能を有する変異体ポリペプチドおよびその使用
MX2018014247A (es) 2016-05-20 2019-08-12 Stepan Co Composiciones de polieteramina para detergentes para lavanderia.
CN109563450A (zh) 2016-05-31 2019-04-02 诺维信公司 稳定的液体过氧化物组合物
EP3464582A1 (en) 2016-06-03 2019-04-10 Novozymes A/S Subtilase variants and polynucleotides encoding same
US20190136162A1 (en) 2016-06-09 2019-05-09 Conopco, Inc., D/B/A Unilever Laundry products
CN109563449B (zh) 2016-06-23 2022-01-25 诺维信公司 酶的用途、组合物以及用于去除污垢的方法
WO2018001959A1 (en) 2016-06-30 2018-01-04 Novozymes A/S Lipase variants and compositions comprising surfactant and lipase variant
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
EP3485011B1 (en) 2016-07-13 2021-06-09 Novozymes A/S Bacillus cibi dnase variants
CN109477065A (zh) 2016-07-14 2019-03-15 巴斯夫欧洲公司 包含螯合剂的发酵培养基
EP4357453A2 (en) 2016-07-18 2024-04-24 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
EP3284805B1 (en) 2016-08-17 2020-02-19 The Procter & Gamble Company Cleaning composition comprising enzymes
CA3031609A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
WO2018037061A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
US11001827B2 (en) 2016-08-24 2021-05-11 Henkel Ag & Co. Kgaa Detergent compositions comprising xanthan lyase variants I
EP3504313A1 (en) 2016-08-24 2019-07-03 Henkel AG & Co. KGaA Detergent composition comprising gh9 endoglucanase variants i
US20190284647A1 (en) 2016-09-29 2019-09-19 Novozymes A/S Spore Containing Granule
EP3519548A1 (en) 2016-09-29 2019-08-07 Novozymes A/S Use of enzyme for washing, method for washing and warewashing composition
BR112019007851B1 (pt) 2016-10-18 2022-10-18 Unilever Ip Holdings B.V. Composição detergente para lavagem de roupas e método doméstico de tratamento de um tecido
WO2018077938A1 (en) 2016-10-25 2018-05-03 Novozymes A/S Detergent compositions
US11753605B2 (en) 2016-11-01 2023-09-12 Novozymes A/S Multi-core granules
JP2019536879A (ja) 2016-12-01 2019-12-19 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 組成物中の酵素の安定化
WO2018108865A1 (en) 2016-12-12 2018-06-21 Novozymes A/S Use of polypeptides
EP3555255B1 (en) 2016-12-15 2020-06-24 Unilever PLC Laundry detergent composition
US20210095268A1 (en) 2017-03-31 2021-04-01 Danisco Us Inc Alpha-amylase combinatorial variants
WO2018178061A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having rnase activity
CN110651041A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
WO2018177936A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
US20200109354A1 (en) 2017-04-04 2020-04-09 Novozymes A/S Polypeptides
CN114480034A (zh) 2017-04-04 2022-05-13 诺维信公司 糖基水解酶
EP3607040A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Polypeptide compositions and uses thereof
EP3385362A1 (en) 2017-04-05 2018-10-10 Henkel AG & Co. KGaA Detergent compositions comprising fungal mannanases
EP3385361B1 (en) 2017-04-05 2019-03-27 Henkel AG & Co. KGaA Detergent compositions comprising bacterial mannanases
WO2018185280A1 (en) 2017-04-06 2018-10-11 Novozymes A/S Cleaning compositions and uses thereof
JP7032430B2 (ja) 2017-04-06 2022-03-08 ノボザイムス アクティーゼルスカブ クリーニング組成物及びその使用
EP3626809A1 (en) 2017-04-06 2020-03-25 Novozymes A/S Cleaning compositions and uses thereof
EP3967756A1 (en) 2017-04-06 2022-03-16 Novozymes A/S Detergent compositions and uses thereof
WO2018184818A1 (en) 2017-04-06 2018-10-11 Novozymes A/S Cleaning compositions and uses thereof
EP3607037A1 (en) 2017-04-06 2020-02-12 Novozymes A/S Cleaning compositions and uses thereof
US20200032170A1 (en) 2017-04-06 2020-01-30 Novozymes A/S Cleaning compositions and uses thereof
US20200190437A1 (en) 2017-04-06 2020-06-18 Novozymes A/S Cleaning compositions and uses thereof
WO2018202846A1 (en) 2017-05-05 2018-11-08 Novozymes A/S Compositions comprising lipase and sulfite
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
US11492605B2 (en) 2017-05-08 2022-11-08 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
US12018235B2 (en) 2017-05-08 2024-06-25 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018224544A1 (en) 2017-06-08 2018-12-13 Novozymes A/S Compositions comprising polypeptides having cellulase activity and amylase activity, and uses thereof in cleaning and detergent compositions
WO2018234056A1 (en) 2017-06-20 2018-12-27 Unilever N.V. PARTICULATE DETERGENT COMPOSITION COMPRISING A FRAGRANCE
WO2018234003A1 (en) 2017-06-21 2018-12-27 Unilever Plc PACKAGING AND DISTRIBUTION OF DETERGENT COMPOSITIONS
CN111108183A (zh) 2017-06-30 2020-05-05 诺维信公司 酶浆液组合物
EP3649221B8 (en) 2017-07-07 2024-05-29 Unilever IP Holdings B.V. Laundry cleaning composition
CN110869480B (zh) 2017-07-07 2021-08-13 联合利华知识产权控股有限公司 增白组合物
EP3665267A1 (en) 2017-08-07 2020-06-17 Novozymes A/S Use of fca control based on ph
EP3668973A2 (en) 2017-08-18 2020-06-24 Danisco US Inc. Alpha-amylase variants
US11525128B2 (en) 2017-08-24 2022-12-13 Novozymes A/S GH9 endoglucanase variants and polynucleotides encoding same
US11359188B2 (en) 2017-08-24 2022-06-14 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
WO2019038187A1 (en) 2017-08-24 2019-02-28 Unilever Plc IMPROVEMENTS RELATING TO THE CLEANING OF FABRICS
WO2019038186A1 (en) 2017-08-24 2019-02-28 Unilever Plc IMPROVEMENTS RELATING TO THE CLEANING OF FABRICS
WO2019038060A1 (en) 2017-08-24 2019-02-28 Henkel Ag & Co. Kgaa DETERGENT COMPOSITION COMPRISING XANTHANE LYASE II VARIANTS
US11624059B2 (en) 2017-08-24 2023-04-11 Henkel Ag & Co. Kgaa Detergent compositions comprising GH9 endoglucanase variants II
CN111247235A (zh) 2017-09-20 2020-06-05 诺维信公司 酶改善吸水性和/或白度的用途
WO2019057902A1 (en) 2017-09-22 2019-03-28 Novozymes A/S NEW POLYPEPTIDES
EP3461892A3 (en) 2017-09-27 2019-06-12 The Procter & Gamble Company Detergent compositions comprising lipases
MX2020002964A (es) 2017-09-27 2020-07-22 Novozymes As Variantes de lipasa y composiciones de microcapsula que comprenden las variantes de lipasa.
BR112020006621A2 (pt) 2017-10-02 2020-10-06 Novozymes A/S polipeptídeos com atividade de mananase e polinucleotídeos codificando os mesmos
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
CN111448302A (zh) 2017-10-16 2020-07-24 诺维信公司 低粉化颗粒
WO2019076800A1 (en) 2017-10-16 2019-04-25 Novozymes A/S CLEANING COMPOSITIONS AND USES THEREOF
EP3697880B1 (en) 2017-10-16 2024-07-24 Novozymes A/S Low dusting granules
WO2019081515A1 (en) 2017-10-24 2019-05-02 Novozymes A/S COMPOSITIONS COMPRISING POLYPEPTIDES HAVING MANNANASE ACTIVITY
US11441136B2 (en) 2017-10-27 2022-09-13 Novozymes A/S DNase variants
ES2908667T3 (es) 2017-10-27 2022-05-03 Procter & Gamble Composiciones detergentes que comprenden variantes polipeptídicas
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
US11767492B2 (en) 2017-11-01 2023-09-26 Novozymes A/S Methods of treating fabric using a Lactobacillus hexosaminidase
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
BR112020008711A2 (pt) 2017-11-01 2020-11-10 Novozymes A/S polipeptídeos e composições que compreendem tais polipeptídeos
WO2019086532A1 (en) 2017-11-01 2019-05-09 Novozymes A/S Methods for cleaning medical devices
MX2020004831A (es) 2017-11-09 2020-10-16 Basf Se Recubrimientos de particulas de enzima que comprenden pigmentos blancos organicos.
EP3714049A1 (en) 2017-11-24 2020-09-30 Novozymes A/S Small enzyme particles for interesterification
EP3717611A1 (en) 2017-11-29 2020-10-07 Basf Se Compositions, their manufacture and use
BR112020010648A2 (pt) 2017-11-30 2021-02-02 Unilever N.V. composição detergente, composição detergente de lavanderia, método para aprimorar limpeza enzimática em água e uso de uma enzima protease
CN111670248A (zh) 2017-12-04 2020-09-15 诺维信公司 脂肪酶变体以及编码其的多核苷酸
JP7309718B2 (ja) 2017-12-20 2023-07-18 ビーエーエスエフ ソシエタス・ヨーロピア 繊維製品に付着した、融解温度が３０℃超のである脂肪化合物を除去するための洗濯用配合物
EP3749761A1 (en) 2018-02-08 2020-12-16 Novozymes A/S Lipases, lipase variants and compositions thereof
CN111801416A (zh) 2018-02-08 2020-10-20 诺维信公司 脂肪酶变体及其组合物
US20210102184A1 (en) 2018-02-23 2021-04-08 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase and endoglucanase variants
US20210002588A1 (en) 2018-03-13 2021-01-07 Novozymes A/S Microencapsulation Using Amino Sugar Oligomers
EP3768835A1 (en) 2018-03-23 2021-01-27 Novozymes A/S Subtilase variants and compositions comprising same
WO2019185726A1 (en) 2018-03-29 2019-10-03 Novozymes A/S Mannanase variants and polynucleotides encoding same
CN112262207B (zh) 2018-04-17 2024-01-23 诺维信公司 洗涤剂组合物中包含碳水化合物结合活性的多肽及其在减少纺织品或织物中的褶皱的用途
CN118530973A (zh) 2018-04-19 2024-08-23 诺维信公司 稳定化的纤维素酶变体
CN111989389A (zh) 2018-04-19 2020-11-24 巴斯夫欧洲公司 组合物以及可用于该组合物的聚合物
CN112272701B (zh) 2018-04-19 2024-05-14 诺维信公司 稳定化的纤维素酶变体
WO2019219531A1 (en) 2018-05-17 2019-11-21 Unilever Plc Cleaning composition
WO2019219302A1 (en) 2018-05-17 2019-11-21 Unilever Plc Cleaning composition comprising rhamnolipid and alkyl ether carboxylate surfactants
WO2019238761A1 (en) 2018-06-15 2019-12-19 Basf Se Water soluble multilayer films containing wash active chemicals and enzymes
CN112368363A (zh) 2018-06-28 2021-02-12 诺维信公司 洗涤剂组合物及其用途
WO2020002608A1 (en) 2018-06-29 2020-01-02 Novozymes A/S Detergent compositions and uses thereof
EP3814489A1 (en) 2018-06-29 2021-05-05 Novozymes A/S Subtilase variants and compositions comprising same
US12012573B2 (en) 2018-07-02 2024-06-18 Novozymes A/S Cleaning compositions and uses thereof
WO2020007875A1 (en) 2018-07-03 2020-01-09 Novozymes A/S Cleaning compositions and uses thereof
WO2020008024A1 (en) 2018-07-06 2020-01-09 Novozymes A/S Cleaning compositions and uses thereof
EP3818140A1 (en) 2018-07-06 2021-05-12 Novozymes A/S Cleaning compositions and uses thereof
EP3824057B1 (en) 2018-07-17 2023-10-18 Unilever Global IP Limited Use of a rhamnolipid in a surfactant system
CN112543801A (zh) 2018-07-27 2021-03-23 荷兰联合利华有限公司 洗衣洗涤剂
CA3108284A1 (en) 2018-07-31 2020-02-06 Danisco Us Inc Variant alpha-amylases having amino acid substitutions that lower the pka of the general acid
WO2020030623A1 (en) 2018-08-10 2020-02-13 Basf Se Packaging unit comprising a detergent composition containing an enzyme and at least one chelating agent
US20210340466A1 (en) 2018-10-01 2021-11-04 Novozymes A/S Detergent compositions and uses thereof
WO2020070014A1 (en) 2018-10-02 2020-04-09 Novozymes A/S Cleaning composition comprising anionic surfactant and a polypeptide having rnase activity
EP3861094A1 (en) 2018-10-02 2021-08-11 Novozymes A/S Cleaning composition
WO2020070209A1 (en) 2018-10-02 2020-04-09 Novozymes A/S Cleaning composition
EP3861008A1 (en) 2018-10-03 2021-08-11 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
WO2020070249A1 (en) 2018-10-03 2020-04-09 Novozymes A/S Cleaning compositions
EP3677676A1 (en) 2019-01-03 2020-07-08 Basf Se Compounds stabilizing amylases in liquids
MX2021003930A (es) 2018-10-05 2021-06-04 Basf Se Compuestos estabilizadores de hidrolasas en liquidos.
EP3861114A1 (en) 2018-10-05 2021-08-11 Basf Se Compounds stabilizing amylases in liquids
WO2020069913A1 (en) 2018-10-05 2020-04-09 Basf Se Compounds stabilizing hydrolases in liquids
EP3864124A1 (en) 2018-10-11 2021-08-18 Novozymes A/S Cleaning compositions and uses thereof
US20210355469A1 (en) 2018-10-12 2021-11-18 Danisco Us Inc Alpha-amylases with mutations that improve stability in the presence of chelants
ES2981999T3 (es) 2018-10-31 2024-10-14 Henkel Ag & Co Kgaa Composiciones limpiadoras que contienen dispersinas V
EP3647397A1 (en) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Cleaning compositions containing dispersins iv
WO2020104231A1 (en) 2018-11-19 2020-05-28 Basf Se Powders and granules containing a chelating agent and an enzyme
WO2020104155A1 (en) 2018-11-20 2020-05-28 Unilever Plc Detergent composition
WO2020104157A1 (en) 2018-11-20 2020-05-28 Unilever Plc Detergent composition
CN113056550B (zh) 2018-11-20 2022-10-28 联合利华知识产权控股有限公司 洗涤剂组合物
WO2020104156A1 (en) 2018-11-20 2020-05-28 Unilever Plc Detergent composition
EP3891277A1 (en) 2018-12-03 2021-10-13 Novozymes A/S Powder detergent compositions
EP3891264A1 (en) 2018-12-03 2021-10-13 Novozymes A/S LOW pH POWDER DETERGENT COMPOSITION
CN113330101A (zh) 2018-12-21 2021-08-31 诺维信公司 包含金属蛋白酶的洗涤剂袋
EP3898962A2 (en) 2018-12-21 2021-10-27 Novozymes A/S Polypeptides having peptidoglycan degrading activity and polynucleotides encoding same
WO2020151959A1 (en) 2019-01-22 2020-07-30 Unilever N.V. Laundry detergent
CN113330102B (zh) 2019-01-22 2023-06-02 联合利华知识产权控股有限公司 洗衣洗涤剂
EP3702452A1 (en) 2019-03-01 2020-09-02 Novozymes A/S Detergent compositions comprising two proteases
EP3935148A1 (en) 2019-03-08 2022-01-12 Basf Se Cationic surfactant and its use in laundry detergent compositions
WO2020188095A1 (en) 2019-03-21 2020-09-24 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
MX2021011981A (es) 2019-04-03 2021-11-03 Novozymes As Polipeptidos que tienen actividad de beta-glucanasa, polinucleotidos que los codifican y usos de los mismos en composiciones de limpieza y de detergente.
US20220364138A1 (en) 2019-04-10 2022-11-17 Novozymes A/S Polypeptide variants
BR112021020439A2 (pt) 2019-04-12 2022-05-24 Novozymes As Variantes estabilizadas de glicosídeo hidrolase
WO2020229480A1 (en) 2019-05-14 2020-11-19 Basf Se Compounds stabilizing hydrolases in liquids
US20220195337A1 (en) 2019-05-16 2022-06-23 Conopco, Inc., D/B/A Unilever Laundry composition
EP3744838A1 (en) 2019-05-29 2020-12-02 Novozymes A/S Lipolytic polymer particles for esterification and interesterification
WO2020260006A1 (en) 2019-06-28 2020-12-30 Unilever Plc Detergent compositions
EP3990599B1 (en) 2019-06-28 2023-01-18 Unilever Global Ip Limited Detergent composition
EP3990604B1 (en) 2019-06-28 2022-12-14 Unilever Global IP Limited Detergent composition
CN113891930A (zh) 2019-06-28 2022-01-04 联合利华知识产权控股有限公司 洗涤剂组合物
BR112021025399A2 (pt) 2019-06-28 2022-04-26 Unilever Ip Holdings B V Composição detergente e método doméstico para tratar um tecido
MX2021015894A (es) 2019-07-01 2022-02-03 Basf Se Peptidos acetales para estabilizar enzimas.
CN114207123A (zh) 2019-07-02 2022-03-18 诺维信公司 脂肪酶变体及其组合物
WO2021009067A1 (en) 2019-07-12 2021-01-21 Novozymes A/S Enzymatic emulsions for detergents
WO2021022045A1 (en) 2019-07-31 2021-02-04 Ecolab Usa Inc. Personal protective equipment free delimer compositions
US20220325204A1 (en) 2019-08-27 2022-10-13 Novozymes A/S Detergent composition
US20240294852A1 (en) 2019-08-27 2024-09-05 Novozymes A/S Composition comprising a lipase
BR112022003050A2 (pt) 2019-09-02 2022-05-17 Unilever Ip Holdings B V Composição detergente de lavagem de roupas aquosa e método doméstico para tratar um tecido
EP4031644A1 (en) 2019-09-19 2022-07-27 Novozymes A/S Detergent composition
EP4038170A1 (en) 2019-10-03 2022-08-10 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
AR120142A1 (es) 2019-10-07 2022-02-02 Unilever Nv Composición detergente
WO2021074430A1 (en) 2019-10-18 2021-04-22 Basf Se Storage-stable hydrolase containing liquids
EP4048683A2 (en) 2019-10-24 2022-08-31 Danisco US Inc Variant maltopentaose/maltohexaose-forming alpha-amylases
WO2021105336A1 (en) 2019-11-29 2021-06-03 Basf Se Compositions comprising polymer and enzyme
WO2021115912A1 (en) 2019-12-09 2021-06-17 Basf Se Formulations comprising a hydrophobically modified polyethyleneimine and one or more enzymes
WO2021121394A1 (en) 2019-12-20 2021-06-24 Novozymes A/S Stabilized liquid boron-free enzyme compositions
WO2021122117A1 (en) 2019-12-20 2021-06-24 Henkel Ag & Co. Kgaa Cleaning composition coprising a dispersin and a carbohydrase
US20220411773A1 (en) 2019-12-20 2022-12-29 Novozymes A/S Polypeptides having proteolytic activity and use thereof
EP4077618A1 (en) 2019-12-20 2022-10-26 Henkel AG & Co. KGaA Cleaning compositions comprising dispersins ix
AU2020404593A1 (en) 2019-12-20 2022-08-18 Henkel Ag & Co. Kgaa Cleaning compositions comprising dispersins VI
AU2020404594A1 (en) 2019-12-20 2022-08-18 Henkel Ag & Co. Kgaa Cleaning compositions comprising dispersins VIII
WO2021152120A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
BR112022014946A2 (pt) 2020-01-31 2022-10-04 Novozymes As Variantes de mananase e polinucleotídeos codificando as mesmas
EP3892708A1 (en) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Cleaning compositions comprising dispersin variants
EP4133066A1 (en) 2020-04-08 2023-02-15 Novozymes A/S Carbohydrate binding module variants
WO2021214059A1 (en) 2020-04-21 2021-10-28 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
EP3907271A1 (en) 2020-05-07 2021-11-10 Novozymes A/S Cleaning composition, use and method of cleaning
WO2021239818A1 (en) 2020-05-26 2021-12-02 Novozymes A/S Subtilase variants and compositions comprising same
CN115698246A (zh) 2020-06-08 2023-02-03 联合利华知识产权控股有限公司 提高蛋白酶活性的方法
BR112022025593A2 (pt) 2020-06-18 2023-01-03 Basf Se Composições e seu uso
EP4172298A1 (en) 2020-06-24 2023-05-03 Novozymes A/S Use of cellulases for removing dust mite from textile
EP3936593A1 (en) 2020-07-08 2022-01-12 Henkel AG & Co. KGaA Cleaning compositions and uses thereof
EP4179053B1 (en) 2020-07-09 2024-04-03 Basf Se Compositions and their applications
WO2022008732A1 (en) 2020-07-10 2022-01-13 Basf Se Enhancing the activity of antimicrobial preservatives
CN116057158A (zh) 2020-07-27 2023-05-02 联合利华知识产权控股有限公司 酶和表面活性剂用于抑制微生物的用途
JP2023538740A (ja) 2020-08-25 2023-09-11 ノボザイムス アクティーゼルスカブ ファミリー４４キシログルカナーゼの変異体
WO2022042977A1 (en) 2020-08-28 2022-03-03 Unilever Ip Holdings B.V. Detergent composition
MX2023002095A (es) 2020-08-28 2023-03-15 Novozymes As Variantes de proteasa con solubilidad mejorada.
WO2022043138A1 (en) 2020-08-28 2022-03-03 Unilever Ip Holdings B.V. Surfactant and detergent composition
WO2022043042A1 (en) 2020-08-28 2022-03-03 Unilever Ip Holdings B.V. Detergent composition
WO2022043045A1 (en) 2020-08-28 2022-03-03 Unilever Ip Holdings B.V. Detergent composition
BR112023001773A2 (pt) 2020-08-28 2023-03-28 Unilever Ip Holdings B V Composição detergente e método
EP4217368A1 (en) 2020-09-22 2023-08-02 Basf Se Improved combination of protease and protease inhibitor with secondary enzyme
WO2022074037A2 (en) 2020-10-07 2022-04-14 Novozymes A/S Alpha-amylase variants
WO2022083949A1 (en) 2020-10-20 2022-04-28 Basf Se Compositions and their use
EP4232539A2 (en) 2020-10-20 2023-08-30 Novozymes A/S Use of polypeptides having dnase activity
EP4237525A1 (en) 2020-10-28 2023-09-06 Novozymes A/S Use of lipoxygenase
JP2023547450A (ja) 2020-10-29 2023-11-10 ノボザイムス アクティーゼルスカブ リパーゼ変異体及びそのようなリパーゼ変異体を含む組成物
CN116670261A (zh) 2020-11-13 2023-08-29 诺维信公司 包含脂肪酶的洗涤剂组合物
WO2022106400A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of immunochemically different proteases
WO2022106404A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of proteases
CN116583583A (zh) 2020-12-17 2023-08-11 联合利华知识产权控股有限公司 用途和清洁组合物
WO2022128781A1 (en) 2020-12-17 2022-06-23 Unilever Ip Holdings B.V. Cleaning composition
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
EP4032966A1 (en) 2021-01-22 2022-07-27 Novozymes A/S Liquid enzyme composition with sulfite scavenger
EP4284905A1 (en) 2021-01-28 2023-12-06 Novozymes A/S Lipase with low malodor generation
EP4039806A1 (en) 2021-02-04 2022-08-10 Henkel AG & Co. KGaA Detergent composition comprising xanthan lyase and endoglucanase variants with im-proved stability
CN117015592A (zh) 2021-02-12 2023-11-07 诺维信公司 稳定的生物洗涤剂
CN116829709A (zh) 2021-02-12 2023-09-29 诺维信公司 α-淀粉酶变体
EP4047088A1 (en) 2021-02-22 2022-08-24 Basf Se Amylase variants
MX2023009756A (es) 2021-02-22 2023-09-04 Basf Se Variantes de amilasa.
WO2022189521A1 (en) 2021-03-12 2022-09-15 Novozymes A/S Polypeptide variants
WO2022194673A1 (en) 2021-03-15 2022-09-22 Novozymes A/S Dnase variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
US20240218300A1 (en) 2021-03-26 2024-07-04 Novozymes A/S Detergent composition with reduced polymer content
CN117120601A (zh) * 2021-03-30 2023-11-24 丰益国际有限公司 米黑根毛霉脂肪酶变体及其用途
WO2022268885A1 (en) 2021-06-23 2022-12-29 Novozymes A/S Alpha-amylase polypeptides
WO2023041694A1 (en) 2021-09-20 2023-03-23 Unilever Ip Holdings B.V. Detergent composition
EP4416256A1 (en) 2021-10-13 2024-08-21 Basf Se Compositions comprising polymers, polymers, and their use
WO2023088777A1 (en) 2021-11-22 2023-05-25 Basf Se Compositions comprising polymers, polymers, and their use
CN118647716A (zh) 2021-12-16 2024-09-13 丹尼斯科美国公司 成麦芽五糖/麦芽六糖变体α-淀粉酶
WO2023117957A1 (en) 2021-12-21 2023-06-29 Basf Se Battery passport
WO2023116569A1 (en) 2021-12-21 2023-06-29 Novozymes A/S Composition comprising a lipase and a booster
EP4206309A1 (en) 2021-12-30 2023-07-05 Novozymes A/S Protein particles with improved whiteness
MX2024009542A (es) 2022-02-04 2024-08-19 Basf Se Composiciones que comprenden polimeros, polimeros y su uso.
EP4234664A1 (en) 2022-02-24 2023-08-30 Evonik Operations GmbH Composition comprising glucolipids and enzymes
CN118660951A (zh) 2022-03-02 2024-09-17 诺维信公司 木葡聚糖酶用于改善洗涤剂的可持续性的用途
AU2023228020A1 (en) 2022-03-04 2024-07-11 Novozymes A/S Dnase variants and compositions
AU2023250091A1 (en) 2022-04-08 2024-10-03 Novozymes A/S Hexosaminidase variants and compositions
DE102022205593A1 (de) 2022-06-01 2023-12-07 Henkel Ag & Co. Kgaa Wasch- und reinigungsmittel mit verbesserter enzymstabilität
DE102022205588A1 (de) 2022-06-01 2023-12-07 Henkel Ag & Co. Kgaa Wasch- und reinigungsmittel mit verbesserter enzymstabilität
DE102022205591A1 (de) 2022-06-01 2023-12-07 Henkel Ag & Co. Kgaa Wasch- und reinigungsmittel mit verbesserter enzymstabilität
WO2023247348A1 (en) 2022-06-21 2023-12-28 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2023247664A2 (en) 2022-06-24 2023-12-28 Novozymes A/S Lipase variants and compositions comprising such lipase variants
WO2024033133A2 (en) 2022-08-11 2024-02-15 Basf Se Enzyme compositions comprising an amylase
WO2024033136A1 (en) 2022-08-11 2024-02-15 Basf Se Amylase variants
WO2024033134A1 (en) 2022-08-11 2024-02-15 Basf Se Enzyme compositions comprising protease, mannanase, and/or cellulase
WO2024033135A2 (en) 2022-08-11 2024-02-15 Basf Se Amylase variants
EP4324900A1 (en) 2022-08-17 2024-02-21 Henkel AG & Co. KGaA Detergent composition comprising enzymes
WO2024083589A1 (en) 2022-10-18 2024-04-25 Basf Se Detergent compositions, polymers and methods of manufacturing the same
WO2024094732A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2024094735A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2024094733A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
DE102022131732A1 (de) 2022-11-30 2024-06-06 Henkel Ag & Co. Kgaa Verbesserte Waschleistung durch den Einsatz einer Protease fusioniert mit speziellem Adhäsionsvermittlerpeptid
WO2024115754A1 (en) 2022-12-02 2024-06-06 Basf Se Aqueous compositions containing polyalkoxylates, polyalkoxylates, and use
WO2024121070A1 (en) 2022-12-05 2024-06-13 Novozymes A/S Protease variants and polynucleotides encoding same
WO2024121057A1 (en) 2022-12-05 2024-06-13 Novozymes A/S A composition for removing body grime
WO2024126483A1 (en) 2022-12-14 2024-06-20 Novozymes A/S Improved lipase (gcl1) variants
EP4389864A1 (en) 2022-12-20 2024-06-26 Basf Se Cutinases
WO2024131880A2 (en) 2022-12-23 2024-06-27 Novozymes A/S Detergent composition comprising catalase and amylase
WO2024156628A1 (en) 2023-01-23 2024-08-02 Novozymes A/S Cleaning compositions and uses thereof
WO2024183958A1 (en) 2023-03-09 2024-09-12 Norfalk Aps Use of mono-ester glycolipids in laundry detergents
WO2024194245A1 (en) 2023-03-21 2024-09-26 Novozymes A/S Detergent compositions based on biosurfactants
WO2024213513A1 (en) 2023-04-12 2024-10-17 Novozymes A/S Compositions comprising polypeptides having alkaline phosphatase activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108457A (en) * 1986-11-19 1992-04-28 The Clorox Company Enzymatic peracid bleaching system with modified enzyme
ATE125865T1 (de) * 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.
GB8915658D0 (en) * 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use

Also Published As

Publication number Publication date
EP0548228B1 (en) 1998-08-12
DE69129988T2 (de) 1999-03-18
JPH06501153A (ja) 1994-02-10
BR9106839A (pt) 1993-07-20
CA2092615A1 (en) 1992-03-14
AU657278B2 (en) 1995-03-09
ATE169671T1 (de) 1998-08-15
DK0548228T3 (da) 1999-05-10
DE69129988D1 (de) 1998-09-17
FI931124A (fi) 1993-05-12
AU8617291A (en) 1992-04-15
ES2121786T3 (es) 1998-12-16
WO1992005249A1 (en) 1992-04-02
JP3469234B2 (ja) 2003-11-25
FI931124A0 (fi) 1993-03-12
FI120044B (fi) 2009-06-15
EP0548228A1 (en) 1993-06-30

Similar Documents

Publication Publication Date Title
KR930702514A (ko) 리파제 변체
Schmidt-Dannert Recombinant microbial lipases for biotechnological applications
Sugihara et al. Purification and characterization of a novel thermostable lipase from Bacillus sp.
US5929017A (en) Enzymatic detergent composition
Shu et al. Purification and partial characterization of a lipase from Antrodia cinnamomea
US6350604B1 (en) Alkaline lipolytic enzyme
EP1032654B1 (en) Thermostable glucoamylase
KR950702623A (ko) 칸디다 안탁티카 리파아제 및 리파아제 변이체(c. antarctica lipase and lipase variants)
WO1990009446A1 (en) Cutinase
Turkiewicz et al. A cold-adapted extracellular serine proteinase of the yeast Leucosporidium antarcticum
Yamaguchi et al. Purification and characterization of mono-and diacylglycerol lipase isolated from Penicillium camembertii U-150
JPH06506353A (ja) 新規プロテアーゼ
KR970707275A (ko) 지질분해 활성을 갖는 효소(an enzyme with lipolytic activity)
WO2007087503A1 (en) Polypeptides having lipase activity and polynucleotides encoding same
US20040142441A1 (en) Enzymes with lipase/acyltransferase activity, nucleic acids encoding the same and methods of use thereof
EP0817838B1 (en) Alkaline lipolytic enzyme
US5919746A (en) Alkaline lipolytic enzyme
JP7063807B2 (ja) 安定性に優れたリパーゼ活性を有するポリペプチド
Dosanjh et al. Biochemical analysis of a native and proteolytic fragment of a high-molecular-weight thermostable lipase from a mesophilic Bacillus sp.
JP3126732B2 (ja) 新規プロテアーゼ
GB2401866A (en) Esterases with lipase activity
KR100245618B1 (ko) 새로운 프로테아제
Tulin et al. A Bacillus stearothermophilus esterase produced by a recombinant Bacillus brevis stabilized by sulfhydryl compounds
JPH06506352A (ja) 新規プロテアーゼ
Vakhlu et al. Purification and properties of enantioselective ester hydrolase from a strain of Trichosporon species (DSMZ 11829)

Legal Events

Date Code Title Description
A201 Request for examination
E801 Decision on dismissal of amendment
E902 Notification of reason for refusal
E601 Decision to refuse application