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KR930012045A - 분말 흡입기 - Google Patents

분말 흡입기 Download PDF

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Publication number
KR930012045A
KR930012045A KR1019920023658A KR920023658A KR930012045A KR 930012045 A KR930012045 A KR 930012045A KR 1019920023658 A KR1019920023658 A KR 1019920023658A KR 920023658 A KR920023658 A KR 920023658A KR 930012045 A KR930012045 A KR 930012045A
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South Korea
Prior art keywords
powder inhaler
cylinder
chamber
air
housing
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KR1019920023658A
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KR100218816B1 (ko
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레르크 코엔라트
데 뵈르 안네 하
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후베르트 봅; 라이너 토이브너
아스타 메디카 악티엔게젤샤프트
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Publication of KR930012045A publication Critical patent/KR930012045A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Basic Packing Technique (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Disintegrating Or Milling (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Materials For Photolithography (AREA)
  • Gyroscopes (AREA)
  • Steroid Compounds (AREA)

Abstract

분말 흡입기는 활성물질 혼합물로 충진된 챔버가 언제나 공기 입구 개구의 진압에 위치되는 식으로, 회전 및 변위에 의한 제어커브 매카니즘의 조력으로 이동되는 회진 및 변위가능한 활성물질 매거진을 가진다. 환자의 호흡공기 스트림은 공기 스트림이 활성물질 혼합물을 가진 챔버를 속을 비우게 하는 식으로, 장치를 통해 안내된다. 활성물질 혼합물은 사이클론 챔버에서 또는 출격판에 대해서 호흡가능한 입자로 쪼개져서, 순수공기의 재킷 스트림으로 덮혀져 흡입된다.

Description

분말 흡입기
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 제1실시예에 따른 흡입기의 전체 분해사시도,
제2도는 공기흐름을 갖는 제1실시예에 따른 흡입기의 종단면도,
제3도는 제2도의 Ⅲ-Ⅲ선을 따른 단면도.

Claims (19)

  1. 활성물로 채워진 공기에 의해 환자쪽으로 향한 하우징의 단부에 배치된 마우스피스 개구(10a)와, 하우징부가 서로에 대해 이동할 수 있게 설계되어 있고 이중 하나의 하우징부는 공기를 위한 입구 개구(23)를 갖는 흡입기를 통해 안내된 공기 흐름안으로 활성물을 합체시키기 위한 장치를 갖는 활성물 매거진(1,2)으로 이루어진 분말흡입기에 있어서, 하부 외경을 갖는 중공 원통형 하우징 하부 부분은 하우징이 하부 부분이 축방향에서 하우징의 상부부분 안으로 삽입되게 구비되어 있으며 하우징의 상부 부분에서 그의 종방향 축에 대해 회전가능하며, 실린더는 외부 중공 실린더(3)를 갖는 하우징의 하부에 동심적으로 구비되어 있고, 링 도관(53) 이 중공 활성물 매거진(1,2)을 수용할 수 있게 형성되도록 소경을 갖는 내부 중공 실린더(4)는 링 도관(53)에 대한 통로 개구(16)를 가지며, 하우징의 하부에 있는 입구 개구(23)는 내부 중공 실린더(4)의 내부 공간(43)을 갖는 직접 관통 연결부에 있고, 도관(43)의 상부 단부는 사이클론 챔버(41)애서 활성물로 채워진 공기를 위한 통로 개구(37)를 가지며, 사이클론 챔버(41)는 링도관에서 그의 종방향 축에 대해 활성물 매거진의 회전 또는 축방향 변위를 허용하도록 제공되며, 큰 외경을 갖는 가이드 실린더(7)는 종방향 채널(54)이 하단부로부터 중공 실린더의 중심에 대해 배치된 링 도관(53)에 있는 통로 개구(14)까지 외부 중공 실린더(3)의 외벽에 제공하며, 하우징(9)의 하부의 입구개구(23)는 내부 중공 실린더(4)의 내부 공간(43)을 가진 직접 관통 연결부에 있고, 챔버(41)에 대한 통로 개구(37)는 내부 공간의 상단부에 제공되며, 또한, 입구 개구로부터 외부 중공 실린더의 외측부상의 종방향 채널(15)까지의 관통 연결부가 제공되고, 링 도관의 구동축에 대한 활성물질 매거진의 축방향 변위 및 회전을 허용하는 장치가 제공된 것을 특징으로 하는 분말 흡입기.
  2. 제1항에 있어서, 링 도관(53)의 구동축(18,19)에 대한 활성물질 매거진(55)의 회전 및 축변위를 허용하는 장치는 래칫 퍼로우 실린더(8)의 내측부에 있는 홈(8a)은 물론, 래칫 퍼로우 실린더(8)의 캠 종동부(21) 및 안내실린더(7)의 외측부상의 제어 커브(18,19)로 구성된 것을 특징으로 하는 분말 흡입기.
  3. 제1항에 있어서, 제어 커브(19)는 일회용 투약 실린더(55)의 활성물질 챔버(12)가 비워진후, 하부(8,9)가 분말 흡입기의 상부(10,11)의 이동후 안내 실린더(7)로부터 축방향으로 분리될 수 있도록 설계된 것을 특징으로하는 분말 흡입기.
  4. 제1항에 있어서, 투약 디스크(1)에는 투약 디스크를 상호 구동시키는 수단이 제공된 것을 특징으로 하는 분말 흡입기.
  5. 제4항에 있어서, 투약 디스크(1)는 캠(45) 및 함몰부(46)에 의해 서로 구동되어, 개구(52)의 전방으로 안내되는 것을 특징으로 하는 분말 흡입기.
  6. 제1항에 있어서, 각 투약 디스크(1)는 디스크의 핀(47) 침투가능한 보링(48)에 의해 이동되는 것을 특징으로 하는 분말 흡입기.
  7. 제6항에 있어서, 투약 디스크(1)의 투약실(12)을 내부 투약 실린더의 방향으로 보다 커진 단면을 갖는 것을 특징으로 하는 분말 흡입기.
  8. 제1항에 있어서, 공기는 흡입기로부터 투약실(12)로 축방향 이송되어, 그후 분출실(91)로 축방향 이송되는것을 특징으로 하는 분말 흡입기.
  9. 제1항에 있어서, 공기는 흡입기로부터 투약실(12,104)을 통해 분출실(89)로 축방향 이송되는 것을 특징으로하는 분말 흡입기.
  10. 제1항 내지 제9항중 어느 한 항에 있어서, 마우스피스(11)는 사이클론 챔버(41)와 마우스피스 개구(10a)사이의 하우징 상부에 위치되고, 마우스피스(11)는 활성물질을 가진 공기를 위한 유출 실린더(29)를 포함하고, 재킷 스트림 공기를 위한 링 도관(58)은 유출 실린더(29)에 대해 동심 배열된 것을 특징으로 하는 분말 흡입기.
  11. 제1항 내지 제9항중 어느 한 항에 있어서, 마우스피스 실린더(29)는 공기 스트림의 방향으로 증가된 직경의 도관(57)을 가진 것을 특징으로 하는 분말 흡입기.
  12. 제1항 내지 제9항중 어느 한 항에 있어서, 사이클론 챔버(41)는 활성물질 혼합물 또는 활성물질 및 보조물질의 혼합체를 분할시키는 작용을 하는 것을 특징으로 하는 분말 흡입기.
  13. 제1항 내지 제9항중 어느 한 항에 있어서, 투약을 위한 활성물질 챔버(12)의 보조 물질과 생물학적 활성물질의 물질 혼합물의 양은 0.05mg 내지 50mg인 것을 특징으로 하는 분말 흡입기.
  14. 제1항 내지 제9항중 어느 한 항애 있어서, 투약을 위한 활성물질 챔버(12)의 생물학적 활성물질의 양은 0.025mg 내지 50mg인 것을 특징으로 하는 분말 흡입기.
  15. 제1항 내지 제9항중 어느 한 항에 있어서, 일직선 마우스피스(11) 대신에 굴곡 마우스피스(50)를 갖는 것을 특징으로 하는 분말 흡입기.
  16. 제1항 내지 제9항중 어느 한 항에 있어서, 활성물질 매거진(1,2)은 환상형이고, 활성물질 혼합물 또는 활성물질과 보조물질의 혼합물을 위한 복수의 챔버(12)를 갖는 것을 특징으로 하는 분말 흡입기.
  17. 제1항 내지 제9항중 어느 한 항에 있어서, 내부 도관(43)은 개구(16)에 대향된 단면의 압축부를 가진 것을 특징으로 하는 분말 흡입기.
  18. 제1항 내지 제9항중 어느 한 항에 있어서, 공기 스트림을 조절하는 장치를 포함하는 것을 특징으로 하는 분말 흡입기.
  19. 제1항 대지 제9항중 어느 한 항에 있어서, 공기 스트림은 밸브본체(111)와 탄성막(112)으로 이루어진 장치에 의해 조절되는 것을 특징으로 하는 분말 흡입기.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019920023658A 1991-12-14 1992-12-09 분말 흡입기 KR100218816B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4141363 1991-12-14
DEP4141363.6 1991-12-14
DE4211475A DE4211475A1 (de) 1991-12-14 1992-04-06 Pulverinhalator
DEP4211475.6 1992-04-06

Publications (2)

Publication Number Publication Date
KR930012045A true KR930012045A (ko) 1993-07-20
KR100218816B1 KR100218816B1 (ko) 1999-10-01

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US (1) US5301666A (ko)
EP (1) EP0547429B1 (ko)
JP (1) JP3494669B2 (ko)
KR (1) KR100218816B1 (ko)
CN (1) CN1089255C (ko)
AT (1) ATE139453T1 (ko)
BR (1) BR9204987A (ko)
CA (1) CA2084832C (ko)
DE (2) DE4211475A1 (ko)
HU (1) HU214757B (ko)
IL (1) IL103908A (ko)
TW (1) TW264391B (ko)

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DE59206614D1 (de) 1996-07-25
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JP3494669B2 (ja) 2004-02-09
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EP0547429A1 (de) 1993-06-23
US5301666A (en) 1994-04-12
IL103908A0 (en) 1993-04-04
JPH05245201A (ja) 1993-09-24
HU214757B (hu) 1998-05-28
BR9204987A (pt) 1993-06-15
DE4211475A1 (de) 1993-06-17
ATE139453T1 (de) 1996-07-15
CN1089255C (zh) 2002-08-21
HU9203945D0 (en) 1993-04-28
CN1074381A (zh) 1993-07-21
CA2084832C (en) 2000-10-03
CA2084832A1 (en) 1993-06-15
KR100218816B1 (ko) 1999-10-01
IL103908A (en) 1996-10-16

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