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KR850001282A - 심근 미오신 중사슬에 대한 단일클론항체 - Google Patents

심근 미오신 중사슬에 대한 단일클론항체 Download PDF

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Publication number
KR850001282A
KR850001282A KR1019840003916A KR840003916A KR850001282A KR 850001282 A KR850001282 A KR 850001282A KR 1019840003916 A KR1019840003916 A KR 1019840003916A KR 840003916 A KR840003916 A KR 840003916A KR 850001282 A KR850001282 A KR 850001282A
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KR
South Korea
Prior art keywords
heavy chain
myosin heavy
myocardial myosin
monoclonal antibodies
myocardial
Prior art date
Application number
KR1019840003916A
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English (en)
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KR910008637B1 (ko
Inventor
요시오 야자끼 (외 1)
Original Assignee
하마구찌 미찌오
야마사 쇼오유 가부시끼 가이샤
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Application filed by 하마구찌 미찌오, 야마사 쇼오유 가부시끼 가이샤 filed Critical 하마구찌 미찌오
Publication of KR850001282A publication Critical patent/KR850001282A/ko
Application granted granted Critical
Publication of KR910008637B1 publication Critical patent/KR910008637B1/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1075Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809Fused cells, e.g. hybridoma

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

내용 없음

Description

심근 미오신 중사슬에 대한 단일클론항체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제7도는 본 발명 항제의 사용으로 조직 염색됨에 따라 심방압과 심방근중의 V3미오신 아아소자임(β형)의 비율간의 관계를 나타내는 그래프이다.

Claims (3)

  1. 심근미오신 중사슬의 아이소자임에 대해 특이성이 있는 단일클론 항체.
  2. 제1항에 있어서, 심근 미오신 중사슬 α형에 대해 특이성이 있으나 심근 미오신 중사슬 β형은 식별하지 못하는 단일클론항체.
  3. 제1항에 있어서, 심근 미오신 중사슬 β형에 대해 특이성이 있으나 심근미오신 중사슬 α형은 식별하지 못하는 단일클론항체.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840003916A 1983-07-06 1984-07-06 심근 미오신 중사슬에 대한 단일클론항체 KR910008637B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP122579 1983-07-06
JP???58-122579 1983-07-06
JP58122579A JPS6028998A (ja) 1983-07-06 1983-07-06 心筋ミオシン重鎖に対する単一クロ−ン抗体

Publications (2)

Publication Number Publication Date
KR850001282A true KR850001282A (ko) 1985-03-18
KR910008637B1 KR910008637B1 (ko) 1991-10-19

Family

ID=14839400

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840003916A KR910008637B1 (ko) 1983-07-06 1984-07-06 심근 미오신 중사슬에 대한 단일클론항체

Country Status (7)

Country Link
US (1) US4767843A (ko)
EP (1) EP0131834B1 (ko)
JP (1) JPS6028998A (ko)
KR (1) KR910008637B1 (ko)
AU (1) AU570696B2 (ko)
CA (1) CA1225608A (ko)
DE (1) DE3485965T2 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60201260A (ja) * 1984-03-27 1985-10-11 Yamasa Shoyu Co Ltd 心疾患診断薬
JPH0625762B2 (ja) * 1985-06-13 1994-04-06 ヤマサ醤油株式会社 ミオシン軽鎖の測定法
GB2200358B (en) * 1987-01-27 1991-02-27 Univ Birmingham Materials for in vivo detection of cardiac damage, and methods for their preparation
US5046499A (en) * 1988-06-13 1991-09-10 Centocor, Inc. Method for myocardial infarct risk assessment
CA2050941C (en) * 1989-03-28 1999-02-23 Ryozo Nagai Antibody to smooth muscle myosin heavy chains
US5830720A (en) * 1989-04-21 1998-11-03 Boehringer Mannheim Gmbh Recombinant DNA and expression vector for the repressible and inducible expression of foreign genes
US5364612A (en) * 1991-05-06 1994-11-15 Immunomedics, Inc. Detection of cardiovascular lesions
CA2202913C (en) * 1994-10-25 2004-07-13 Hirohisa Katoh Antibody reagent for detecting dissecting aortic aneurysm and uses thereof
JP4035167B2 (ja) * 1996-02-19 2008-01-16 ヤマサ醤油株式会社 血管障害性疾患用診断薬
US6248869B1 (en) 1997-05-29 2001-06-19 Medical Analysis Systems, Inc. Troponin I forms and use of the same

Also Published As

Publication number Publication date
JPS6028998A (ja) 1985-02-14
DE3485965T2 (de) 1993-03-18
KR910008637B1 (ko) 1991-10-19
CA1225608A (en) 1987-08-18
EP0131834A3 (en) 1987-06-24
AU3022884A (en) 1985-01-10
DE3485965D1 (de) 1992-12-03
JPH0231958B2 (ko) 1990-07-17
EP0131834A2 (en) 1985-01-23
EP0131834B1 (en) 1992-10-28
AU570696B2 (en) 1988-03-24
US4767843A (en) 1988-08-30

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