KR850000973A - 아클라루비신 또는 이의 염산염의 유성 조성물의 제조방법 - Google Patents
아클라루비신 또는 이의 염산염의 유성 조성물의 제조방법 Download PDFInfo
- Publication number
- KR850000973A KR850000973A KR1019840004123A KR840004123A KR850000973A KR 850000973 A KR850000973 A KR 850000973A KR 1019840004123 A KR1019840004123 A KR 1019840004123A KR 840004123 A KR840004123 A KR 840004123A KR 850000973 A KR850000973 A KR 850000973A
- Authority
- KR
- South Korea
- Prior art keywords
- aclarubicin
- fatty acids
- hydrochloride salt
- oily composition
- hydrochloride
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
본 도표는 Ⅰ군 내지 Ⅴ군에 대한 암성포의 크기변화 및 괴사율을 나타낸 것이다.
Claims (2)
- 아클라루비신 또는 아클라루비신 염산염을, 포화중쇄지방산, 불포화 중쇄 지방산 및 불포화 장쇄 지방산 중에서 선택된 하나 이상의 지방산 및 요오드화유 및 식물성유 중에서 선택된 하나 이상의 지방 및 오일에 용해시킴을 특징으로 하는, 아클라루비신 또는 이의 염산염의 유성 조성물의 제조방법.
- 제1항에 있어서, 지방산의 배합비가 아클라-루비신 염산염 1중량부당 10 내지 1,000 중량부 이거나, 아클라루비신 1중량부당 1 내지 1,000 중량부인 방법.※참고사항 : 최초출원 내요에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58-127092 | 1983-07-13 | ||
| JP127092/83 | 1983-07-13 | ||
| JP58127092A JPS6028916A (ja) | 1983-07-13 | 1983-07-13 | アクラルビシンまたはその塩酸塩の油性組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR850000973A true KR850000973A (ko) | 1985-03-14 |
| KR910002638B1 KR910002638B1 (ko) | 1991-04-27 |
Family
ID=14951379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019840004123A KR910002638B1 (ko) | 1983-07-13 | 1984-07-13 | 아클라루비신 또는 이의 염산염의 유성 조성물의 제조방법 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4772590A (ko) |
| EP (1) | EP0132105B1 (ko) |
| JP (1) | JPS6028916A (ko) |
| KR (1) | KR910002638B1 (ko) |
| DE (1) | DE3483500D1 (ko) |
| ES (1) | ES8602410A1 (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61189215A (ja) * | 1985-02-18 | 1986-08-22 | Teijin Ltd | ５−フルオロ−２′−デオキシウリジンエステル類の油状医薬組成物 |
| WO1993005774A1 (en) * | 1991-09-25 | 1993-04-01 | Wisconsin Alumni Research Foundation | Complexes of anthracycline antibiotics with polyunsaturated fatty acids in lipid emulsions |
| US6426367B1 (en) * | 1999-09-09 | 2002-07-30 | Efa Sciences Llc | Methods for selectively occluding blood supplies to neoplasias |
| US20060034878A1 (en) * | 2004-08-16 | 2006-02-16 | Satterfield Artus L | Iodized oil |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH229981A (de) * | 1939-02-08 | 1943-11-30 | Knoll Ag | Verfahren zur Herstellung einer strychninoxydhaltigen Lösung. |
| JPS5134915B2 (ko) * | 1974-07-27 | 1976-09-29 | ||
| FR2498075B2 (fr) * | 1980-01-25 | 1985-07-12 | Oreal | Solution stable a l'oxydation d'un acide gras essentiel ou d'un melange de ces acides et compositions cosmetiques la contenant |
| DE3105483A1 (de) * | 1981-02-14 | 1982-09-09 | Behringwerke Ag, 3550 Marburg | "verwendung von aclacinomycin als immunsuppressivum" |
| US4578391A (en) * | 1982-01-20 | 1986-03-25 | Yamanouchi Pharmaceutical Co., Ltd. | Oily compositions of antitumor drugs |
-
1983
- 1983-07-13 JP JP58127092A patent/JPS6028916A/ja active Granted
-
1984
- 1984-07-10 DE DE8484304702T patent/DE3483500D1/de not_active Expired - Fee Related
- 1984-07-10 EP EP84304702A patent/EP0132105B1/en not_active Expired - Lifetime
- 1984-07-12 ES ES534261A patent/ES8602410A1/es not_active Expired
- 1984-07-13 KR KR1019840004123A patent/KR910002638B1/ko not_active IP Right Cessation
-
1986
- 1986-06-27 US US06/880,633 patent/US4772590A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US4772590A (en) | 1988-09-20 |
| EP0132105A3 (en) | 1986-08-27 |
| JPH0463048B2 (ko) | 1992-10-08 |
| EP0132105A2 (en) | 1985-01-23 |
| ES534261A0 (es) | 1985-11-16 |
| EP0132105B1 (en) | 1990-10-31 |
| DE3483500D1 (de) | 1990-12-06 |
| ES8602410A1 (es) | 1985-11-16 |
| KR910002638B1 (ko) | 1991-04-27 |
| JPS6028916A (ja) | 1985-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19950404 Year of fee payment: 5 |
|
| LAPS | Lapse due to unpaid annual fee |