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KR840006979A - 1-아졸릴-2-아릴-3-플루오로알칸-2-올유도체의 제조방법 - Google Patents

1-아졸릴-2-아릴-3-플루오로알칸-2-올유도체의 제조방법 Download PDF

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KR840006979A
KR840006979A KR1019830005924A KR830005924A KR840006979A KR 840006979 A KR840006979 A KR 840006979A KR 1019830005924 A KR1019830005924 A KR 1019830005924A KR 830005924 A KR830005924 A KR 830005924A KR 840006979 A KR840006979 A KR 840006979A
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triazol
phenyl
hydrogen
formula
dichlorophenyl
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KR910002541B1 (ko
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수투름(외 1) 엘마르
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아놀드 자일러, 에른스트 알테르
시바-가이기 에이 쥐
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    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N43/501,3-Diazoles; Hydrogenated 1,3-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
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    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
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    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
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    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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Abstract

내용 없음

Description

1―아졸릴―2―아릴―3―플로오로알칸―2―올유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (38)

  1. 하기식(II)의 옥시란을 하기식(III)의 아졸과 반응시켜 생성된 하기식(Ia)의 알코올을 하기식(IV)의 화합물과 반응시켜 에테르로 전환시키는 것으로 구성된 하기식(I)의 1―아졸릴―2―아릴―3―플로오로알칸―2―올유도체 및 산부가염, 4차 아졸률염과 금속착물의 제조방법.
  2. 상기식에서
  3. Az는 1H―1,2,4―트리아졸, 4H―1,2,4―트리아졸 또는 1H―이미다졸
  4. Ar은 치환되지 않았거나 치환된 방향 족 라디칼로 페닐, 비페닐, 페녹시페닐, 나프틸로부터 선택된다.
  5. R1은 수소, C1―C4―알킬, C3―C5―알케닐, 벤질
  6. R2는 수소, C1―C6―알킬
  7. R3는 수소, 불소, C1―C6알킬, C1―C6―할로알킬, C1―C6―알콕시, C1―C6―알킬티오, 페닐, 페녹시, 페닐티오, C3―C7―시클로알킬인데 각각의 방향족 치환체 또는 치환체의 방향족부는 치환되지 않거나 할로겐 C1―C4―알킬, C1―C4―알콕시, C1―C4―할로알킬, 니트로 및/혹은 시아노로 단일―또는 다중 치환된다.
  8. M은 수소 또는 금속원자
  9. W는 OH 또는 종래의 이탈기.
  10. 제1항에 있어서, 식(II)의 옥시란과 식(III)의 아졸을 상대적으로 극성이지만 반응에 불활성인 용매내에서 0°―150℃ 양호하게는 20°―100℃로 반응시키는 제조방법.
  11. 제1 또는 2항에 있어서, Az가 치환되지 않았거나 페닐, 비페닐과 페녹시로 치환된 방향족 라디칼: R1이 수소, R2가 수소, 불소 또는 C1―C3―알킬; R3이 수소, 불소, C1―C4―알킬, C1―C3―할로알킬, C1―C3알콕시, C1―C3알킬티오, 페닐, 페녹시 또는 페닐티오며 각각의 페닐부는 치환되지 않았거나 불소, 염소, 브롬, 메틸, 메톡시, CF3, NO2및/혹은 시아노로 치환된 식(I)의 화합물 및 산부가염, 4차 아졸륨염과 금속 착물의 제조방법.
  12. 제3항에 있어서, Az가 1H―1,2,4―트리아졸, Ar이 페닐 또는 페녹시페닐로 치환되지 않았거나 2―/및 혹은 4―위치가 메틸 또는 할로겐으로 치환되었으며: R1은 수소: R2는 수소, 불소 또는 메틸: R3은 수소, 불소, C1―C4알킬 또는 페닐, 페녹시와 페닐티오로부터 선택된 라디칼로서 불소, 염소 및/혹은 브롬으로 치환된 식(I)의 화합물의 제조방법.
  13. 제1 또는 2항에 있어서,
  14. 1-(1H-1,2,4-트리아졸-1-일)-2-(2,4-디클로로페닐)-3-플루오로부탄-2-올,
  15. 1-(1H-1,2,4-트리아졸-1-일)-2-(2-클로로-4-플루오로페닐)-3-플루오로부탄-2-올,
  16. 1-(1H-1,2,4-트리아졸-1-일)-2-(2,4-디클로로페닐)-3-플루오로부탄-2-올,
  17. 1-(1H-1,2,4-트리아졸-1-일)-2-(2,4-디클로로페닐)-3-플루오로-4-메틸페탄-2-올,
  18. 1-(1H-1,2,4-트리아졸-1-일)-2-(2-클로로-4-플루오로페닐)-3-플루오로펜탄-2-올,
  19. 1-(1H-1,2,4-트리아졸-1-일)-2-[P-(4-클로로페녹시)페닐]-3-플루오로프로판-2-올,
  20. 1-(1H-1,2,4-트리아졸-1-일)-2-(2,4-디클로롤페닐)-3-(4-클로로페녹시)-3-플루오로프로판-2-올,
  21. 1-(1--1,2,4-트리아졸-1-일)-2-(4-플루오로페닐)-3,3,3-트리플루오로프로판-2-올,
  22. 1-(1H-1,2,4-트라아졸-1-일)-2-(2,4-디클로로페닐)-3,3,3-트리플루오로 플로판-2-올 중에서 선택된 식(I)의 화합물의 제조방법.
  23. 제1 또는 2항에 있어서,
  24. 1―(1H―1,2,4―트리아졸―1―일)―2―(4―클로로페닐)―3―플루오로헥산―2―올,
  25. 1―(1H―1,2,4―트리아졸―1―일)―2―(2,4―디클로로페닐)―3―플루오로헥산―2―올,
  26. 1―(1H―1,2,4―트리아졸―1―일)―2―(2,4―디클로로페닐)―3,3―디플루오로펜탄―2―올,
  27. 1―(1H―1,2,4―트리아졸―1―일)―2―(2,4―디클로로페닐)―3―플루오로-4-메틸펜탄-2-올,
  28. 1―(1H―1,2,4―트리아졸―1―일)―2―[P-(4-브로모페녹시)페닐]-3,3-디플루오로프로판-2-,올
  29. 1―(1H―1,2,4―트리아졸―1―일)―2―[P-(4-플루오로페녹시)페닐]-3,3-디플루오로프로판-2-올,
  30. 1―(1H―1,2,4―트리아졸―1―일)―2―[P-(4-클로로페녹시)페닐]-3,3-디플루오로프로판-2-올,
  31. 1―(1H―1,2,4―트리아졸―1―일)―2―[P-(4-클로로페녹시)-2-메틸페닐]-2-히드록시-3-프루오로 프로판 중에서 선택된 식(I)의 화합물의 제조방법.
  32. 1―아졸릴―2―아릴―3―플루오로알칸―2―올 유도체의 제조방법.
  33. ※참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019830005924A 1982-12-14 1983-12-14 1-아졸릴-2-아릴-3-플루오로알칸-2-올유도체의 제조방법 KR910002541B1 (ko)

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AU603417B2 (en) 1990-11-15
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NZ206562A (en) 1989-02-24
DE3381589D1 (de) 1990-06-28
AU1075288A (en) 1988-07-28
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DK573883A (da) 1984-06-15
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JPS59118771A (ja) 1984-07-09
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ATE53027T1 (de) 1990-06-15
IL70422A (en) 1989-05-15
CS250237B2 (en) 1987-04-16
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FI834522A0 (fi) 1983-12-09
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PL139146B1 (en) 1986-12-31
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HU196891B (en) 1989-02-28
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PT77797A (de) 1984-01-01
AR240810A2 (es) 1991-02-28
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PH22949A (en) 1989-02-03
HU196978B (en) 1989-02-28
IL70422A0 (en) 1984-03-30
IE56378B1 (en) 1991-07-17
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