KR20200091898A - 세포 농축 및 격리 방법 - Google Patents
세포 농축 및 격리 방법 Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- C12N2509/10—Mechanical dissociation
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- Immunology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US15/829,615 US10696961B2 (en) | 2017-12-01 | 2017-12-01 | Magnetic cell isolation techniques |
| US15/829,615 | 2017-12-01 | ||
| US201862736151P | 2018-09-25 | 2018-09-25 | |
| US201862736170P | 2018-09-25 | 2018-09-25 | |
| US62/736,170 | 2018-09-25 | ||
| US62/736,151 | 2018-09-25 | ||
| PCT/EP2018/083382 WO2019106207A1 (en) | 2017-12-01 | 2018-12-03 | Methods for cell enrichment and isolation |
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| KR20200091898A true KR20200091898A (ko) | 2020-07-31 |
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| SG (1) | SG11202004646TA (zh) |
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| WO2020257335A1 (en) * | 2019-06-17 | 2020-12-24 | Deka Products Limited Partnership | System and method for centralized fluid management and culture control |
| US11000780B1 (en) * | 2019-12-06 | 2021-05-11 | AnuCell Biosystems Limited | Torus reactor for a combined cell isolator and bioreactor |
| US20230101666A1 (en) * | 2020-02-06 | 2023-03-30 | Cutiss Ag | Cell isolation device and method |
| WO2022081519A1 (en) * | 2020-10-12 | 2022-04-21 | Life Technologies As | Magnetic particle processing systems for use with biological cells and related methods |
| CA3205320A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | Methods for cell activation, transduction and expansion |
| CN116507715A (zh) | 2020-12-15 | 2023-07-28 | 环球生命科技咨询美国有限责任公司 | 用于使用质量平衡技术验证生物处理系统的完整性的系统和方法 |
| CA3202851A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | Culture vessel for a bioprocessing system |
| CA3202075A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | Bioprocessing system and methods |
| CA3201296A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | System and method for heat and mass transfer for a bioprocessing system |
| EP4263786A1 (en) | 2020-12-15 | 2023-10-25 | Global Life Sciences Solutions Usa Llc | Apparatus and method for in-line monitoring of a bioprocess fluid |
| WO2022132732A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | System and methods for verifying the integrity of a bioprocessing system using pressurization |
| CN116583344A (zh) | 2020-12-15 | 2023-08-11 | 环球生命科技咨询美国有限责任公司 | 用于混合生物处理系统中的流体的系统、方法和设备 |
| US20240010966A1 (en) | 2020-12-15 | 2024-01-11 | Global Life Sciences Solutions Usa Llc | Systems and methods for cell enrichment, isolation and formulation |
| CA3204821A1 (en) | 2020-12-15 | 2022-06-23 | Global Life Sciences Solutions Usa Llc | Disposable kits for cell washing, magnetic isolation and dosing preparation |
| WO2022214558A1 (en) * | 2021-04-07 | 2022-10-13 | Norgren LLC | Bioprocessing systems |
| WO2023110682A2 (en) * | 2021-12-15 | 2023-06-22 | Norgren LLC | Bioprocessing system and associated sensor manifold |
| CN114563331B (zh) * | 2022-03-22 | 2023-12-19 | 重庆市公共卫生医疗救治中心 | 基于微流控芯片的cd4+t淋巴细胞自动计数检测系统 |
| CN114574323B (zh) * | 2022-03-31 | 2023-04-07 | 江苏莱尔生物医药科技有限公司 | 一种细胞分离装置 |
| WO2023215876A1 (en) * | 2022-05-06 | 2023-11-09 | Tissue Genesis International Llc | Method for isolation of pancreatic islets |
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| WO2024047359A1 (en) * | 2022-08-31 | 2024-03-07 | Cellular Origins Limited | Automated fill / finish system |
| WO2024091900A1 (en) * | 2022-10-24 | 2024-05-02 | National Resilience, Inc. | Systems, methods, and compositions for selecting or isolating cells |
| WO2024215466A1 (en) * | 2023-04-12 | 2024-10-17 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods and systems for tissue perfusion |
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| US7217565B2 (en) * | 1999-02-12 | 2007-05-15 | Stemcells California, Inc. | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations |
| US6159378A (en) | 1999-02-23 | 2000-12-12 | Battelle Memorial Institute | Apparatus and method for handling magnetic particles in a fluid |
| DE60040543D1 (de) | 1999-07-19 | 2008-11-27 | Biomerieux Bv | Verfahren zum mengen von magnetteilchen mit einer flüssigkeit |
| AU5967100A (en) * | 1999-07-21 | 2001-02-13 | Britta Christensen | A novel method for the improved isolation of a target cell population |
| DE102004040785B4 (de) * | 2004-08-23 | 2006-09-21 | Kist-Europe Forschungsgesellschaft Mbh | Mikrofluidisches System zur Isolierung biologischer Partikel unter Verwendung der immunomagnetischen Separation |
| JP2009511001A (ja) * | 2005-09-15 | 2009-03-19 | アルテミス ヘルス，インク． | 細胞及びその他の粒子を磁気濃縮するためのデバイス並びに方法 |
| CN101172664A (zh) * | 2006-11-01 | 2008-05-07 | 中国民航大学 | 磁性四氧化三铁纳米超细微粒的超声波辅助水热合成工艺 |
| WO2009072003A2 (en) | 2007-12-07 | 2009-06-11 | Miltenyi Biotec Gmbh | Sample processing system and methods |
| EP2526183A4 (en) * | 2010-01-21 | 2017-05-03 | Biocep Ltd. | Magnetic separation of rare cells |
| EP2412802A1 (en) | 2010-07-29 | 2012-02-01 | TXCell | IL-13 producing TR1-like cells and use thereof |
| CN102174465A (zh) * | 2011-01-12 | 2011-09-07 | 武汉格蓝丽富科技有限公司 | 一种从组织中分离富集靶细胞的方法 |
| WO2013048546A1 (en) * | 2011-03-29 | 2013-04-04 | Yongxin Zhang | Multifunctional bioreactor system and methods for cell sorting and culturing |
| US20140295426A1 (en) * | 2011-07-28 | 2014-10-02 | Veridex Llc | Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids |
| CN102504991B (zh) * | 2011-10-11 | 2013-12-04 | 中国人民解放军军事医学科学院卫生装备研究所 | 液样中细菌的非特异性快速富集纯化装置与方法 |
| DK2597153T3 (en) * | 2011-11-25 | 2016-12-05 | Miltenyi Biotec Gmbh | Method for cell separation |
| JP2013223820A (ja) | 2012-04-20 | 2013-10-31 | Hitachi High-Technologies Corp | 磁気分離装置およびこれを備えた自動分析装置、及び分離方法 |
| US9797817B2 (en) * | 2012-05-03 | 2017-10-24 | The Regents Of The University Of Michigan | Multi-mode separation for target detection |
| GB201208547D0 (en) * | 2012-05-15 | 2012-06-27 | Life Technologies As | Sample holder |
| CN102690786B (zh) * | 2012-06-05 | 2014-02-12 | 武汉格蓝丽富科技有限公司 | 一种细胞富集、分离、提取的方法和仪器及单细胞分析方法 |
| FR3009082B1 (fr) * | 2013-07-26 | 2016-10-21 | Centre Nat Rech Scient | Systeme microfluidique et procede pour isoler et quantifier au moins une sous-population de cellules a partir d'une population de cellules. |
| EP3134512B1 (en) * | 2014-04-24 | 2019-01-02 | Miltenyi Biotec GmbH | Method for automated generation of genetically modified t cells |
| US20170268037A1 (en) * | 2014-05-15 | 2017-09-21 | Fluxion Biosciences, Inc. | Methods and systems for cell separation using magnetic-and size-based separation |
| EP3233148B1 (en) * | 2014-12-19 | 2019-04-17 | Biosafe S.A. | Sequential processing of biological fluids |
| EP3037170A1 (en) * | 2014-12-27 | 2016-06-29 | Miltenyi Biotec GmbH | Multisort cell separation method |
| EP3061529A1 (en) * | 2015-02-24 | 2016-08-31 | AdnaGen GmbH | Apparatus and method for the analysis, isolation and/or enrichment of target structures in a fluid sample |
| EP3341893A4 (en) * | 2015-08-24 | 2019-03-06 | GPB Scientific, LLC | METHODS AND DEVICES FOR PURIFICATION AND CONCENTRATION OF MULTI-STEP CELLS |
| CN105606795B (zh) * | 2015-12-31 | 2018-04-24 | 上海白泽医疗器械有限公司 | 一种细胞免疫磁珠分选系统 |
| CN105651680A (zh) * | 2016-02-04 | 2016-06-08 | 关节动力安达（天津）生物科技有限公司 | 鉴定不同免疫磁珠细胞分离器分选细胞效率的方法 |
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2018
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| AU2018376657A1 (en) | 2020-06-11 |
| AU2018376657B2 (en) | 2024-07-25 |
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| CN117343836A (zh) | 2024-01-05 |
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| SG11202004646TA (en) | 2020-06-29 |
| WO2019106207A9 (en) | 2019-08-01 |
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| JP2021503939A (ja) | 2021-02-15 |
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