KR20050084250A - 알츠하이머병의 예방 및 치료 - Google Patents

알츠하이머병의 예방 및 치료 Download PDF

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Publication number: KR20050084250A
Authority: KR; South Korea
Prior art keywords: alkyl; bile acid; disease; inhibitors; compound
Prior art date: 2002-12-12

Application number

KR1020057010595A

Other languages

English (en)

Korean (ko)

Inventor

띠에리 깡똥

로렝 프라디에

헤수스 베나비데스

휴베르트 호이에르

한스-루드빅 쉐페르

Original Assignee

아방티 파르마 소시에테 아노님

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-12

Filing date

2003-12-10

Publication date

2005-08-26

2003-12-10 Application filed by 아방티 파르마 소시에테 아노님 filed Critical 아방티 파르마 소시에테 아노님

2005-08-26 Publication of KR20050084250A publication Critical patent/KR20050084250A/ko

Links

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239000011574 phosphorus Substances 0.000 description 1
229920005862 polyol Polymers 0.000 description 1
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239000002243 precursor Substances 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

KR1020057010595A 2002-12-12 2003-12-10 알츠하이머병의 예방 및 치료 KR20050084250A (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0215722A FR2848452B1 (fr)	2002-12-12	2002-12-12	Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer
FR0215722		2002-12-12

Publications (1)

Publication Number	Publication Date
KR20050084250A true KR20050084250A (ko)	2005-08-26

Family

ID=32338722

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1020057010595A KR20050084250A (ko)	2002-12-12	2003-12-10	알츠하이머병의 예방 및 치료

Country Status (22)

Country	Link
EP (1)	EP1572174A1 (xx)
JP (1)	JP2006514063A (xx)
KR (1)	KR20050084250A (xx)
CN (1)	CN1726016A (xx)
AR (1)	AR042354A1 (xx)
AU (1)	AU2003296802A1 (xx)
BR (1)	BR0317280A (xx)
CA (1)	CA2507945A1 (xx)
CO (1)	CO5700712A2 (xx)
FR (1)	FR2848452B1 (xx)
HR (1)	HRP20050534A2 (xx)
MA (1)	MA27500A1 (xx)
MX (1)	MXPA05005556A (xx)
NO (1)	NO20053341L (xx)
NZ (1)	NZ540496A (xx)
PE (1)	PE20040770A1 (xx)
PL (1)	PL377110A1 (xx)
RS (1)	RS20050420A (xx)
RU (1)	RU2005121909A (xx)
TW (1)	TW200503707A (xx)
WO (1)	WO2004062652A1 (xx)
ZA (1)	ZA200504656B (xx)

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US7521481B2 (en)	2003-02-27	2009-04-21	Mclaurin Joanne	Methods of preventing, treating and diagnosing disorders of protein aggregation
AU2004290499C1 (en)	2003-11-03	2011-02-24	Probiodrug Ag	Combinations useful for the treatment of neuronal disorders
CA2554809C (en)	2004-02-05	2014-04-29	Probiodrug Ag	Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase
CA2589102C (en)	2004-11-02	2013-08-13	Northwestern University	Pyridazine compounds and methods for using the compounds to treat inflammatory diseases
EP2015750A2 (en)	2006-04-28	2009-01-21	Northwestern University	Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
MX2009012583A (es) *	2007-05-22	2010-03-08	Otsuka Pharma Co Ltd	Un medicamento que comprende un derivado de carbostirilo y donepezilo para tratar enfermedad de alzheimer.
US20140243281A1 (en) *	2011-10-28	2014-08-28	Lumena Pharmaceuticals, Inc.	Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
EP2770990A4 (en)	2011-10-28	2015-03-11	Lumena Pharmaceuticals Inc	Gallic acid refluxing agent for the treatment of hypertension and chronic liver disease

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CA2040996A1 (en) *	1990-05-02	1991-11-03	Robert L. Albright	Composition and method for controlling cholesterol
ATE231723T1 (de) *	1991-02-22	2003-02-15	Howard K Shapiro	Verwendung von pharmazeutischen wirkstoffen zur behandlung von krankheitssymptomen neurologischer erkrankungen und etiologisch verwandter symptomenkomplexe
WO1997049736A2 (en) *	1996-06-27	1997-12-31	G.D. Searle And Co.	Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications
US5985936A (en) *	1997-12-18	1999-11-16	Forbes Medi-Tech, Inc.	Method of preventing and delaying onset of Alzheimer's disease and composition therefor
CA2311356C (en) *	1998-01-28	2004-07-13	Warner-Lambert Company	Method for treating alzheimer's disease
US6080778A (en) *	1998-03-23	2000-06-27	Children's Medical Center Corporation	Methods for decreasing beta amyloid protein
US6221897B1 (en) *	1998-06-10	2001-04-24	Aventis Pharma Deutschland Gmbh	Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19825804C2 (de) *	1998-06-10	2000-08-24	Aventis Pharma Gmbh	1,4-Benzothiepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19845405C2 (de) *	1998-10-02	2000-07-13	Aventis Pharma Gmbh	Arylsubstituierte Propanolaminderivate und deren Verwendung
AU2001233299A1 (en) *	2000-02-04	2001-08-14	Esperion Therapeutics Inc.	Methods for treating alzheimer's disease
US20020028826A1 (en) *	2000-06-15	2002-03-07	Robl Jeffrey A.	HMG-CoA reductase inhibitors and method
SE0104334D0 (sv) *	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
TWI329111B (en) *	2002-05-24	2010-08-21	X Ceptor Therapeutics Inc	Azepinoindole and pyridoindole derivatives as pharmaceutical agents

2002
- 2002-12-12 FR FR0215722A patent/FR2848452B1/fr not_active Expired - Fee Related
2003
- 2003-12-10 KR KR1020057010595A patent/KR20050084250A/ko not_active Application Discontinuation
- 2003-12-10 RU RU2005121909/15A patent/RU2005121909A/ru not_active Application Discontinuation
- 2003-12-10 WO PCT/FR2003/003654 patent/WO2004062652A1/fr active Application Filing
- 2003-12-10 NZ NZ540496A patent/NZ540496A/en unknown
- 2003-12-10 AR ARP030104540A patent/AR042354A1/es not_active Application Discontinuation
- 2003-12-10 CA CA002507945A patent/CA2507945A1/fr not_active Abandoned
- 2003-12-10 PL PL377110A patent/PL377110A1/pl not_active Application Discontinuation
- 2003-12-10 JP JP2004566119A patent/JP2006514063A/ja not_active Abandoned
- 2003-12-10 AU AU2003296802A patent/AU2003296802A1/en not_active Abandoned
- 2003-12-10 EP EP03815109A patent/EP1572174A1/fr not_active Withdrawn
- 2003-12-10 CN CNA2003801059727A patent/CN1726016A/zh active Pending
- 2003-12-10 BR BR0317280-5A patent/BR0317280A/pt not_active IP Right Cessation
- 2003-12-10 RS YUP-2005/0420A patent/RS20050420A/sr unknown
- 2003-12-10 PE PE2003001247A patent/PE20040770A1/es not_active Application Discontinuation
- 2003-12-10 MX MXPA05005556A patent/MXPA05005556A/es not_active Application Discontinuation
- 2003-12-11 TW TW092134949A patent/TW200503707A/zh unknown
2005
- 2005-06-07 ZA ZA200504656A patent/ZA200504656B/en unknown
- 2005-06-09 CO CO05056010A patent/CO5700712A2/es not_active Application Discontinuation
- 2005-06-10 MA MA28329A patent/MA27500A1/fr unknown
- 2005-06-10 HR HR20050534A patent/HRP20050534A2/xx not_active Application Discontinuation
- 2005-07-08 NO NO20053341A patent/NO20053341L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2004062652A1 (fr)	2004-07-29
BR0317280A (pt)	2005-11-08
PL377110A1 (pl)	2006-01-23
AR042354A1 (es)	2005-06-15
AU2003296802A1 (en)	2004-08-10
MXPA05005556A (es)	2005-07-26
PE20040770A1 (es)	2004-12-10
MA27500A1 (fr)	2005-08-01
ZA200504656B (en)	2006-08-30
NO20053341L (no)	2005-09-07
RS20050420A (xx)	2007-04-10
RU2005121909A (ru)	2006-01-20
JP2006514063A (ja)	2006-04-27
CN1726016A (zh)	2006-01-25
TW200503707A (en)	2005-02-01
FR2848452A1 (fr)	2004-06-18
EP1572174A1 (fr)	2005-09-14
CO5700712A2 (es)	2006-11-30
CA2507945A1 (fr)	2004-07-29
NO20053341D0 (no)	2005-07-08
FR2848452B1 (fr)	2007-04-06
HRP20050534A2 (en)	2006-11-30
NZ540496A (en)	2008-04-30

Publication	Publication Date	Title
CA2301725C (en)	2008-11-18	Specific saccharide compositions and methods for treating alzheimer's disease and other amyloidoses
JP5816171B2 (ja)	2015-11-18	神経変性障害における脳の健康を保護するための化合物、組成物および方法
JP5302900B2 (ja)	2013-10-02	脂肪性肝疾患の治療用医薬組成物
KR20050084250A (ko)	2005-08-26	알츠하이머병의 예방 및 치료
EP1007040B1 (en)	2002-05-08	Use of phanquinone for the treatment of alzheimer's disease
US20240390377A1 (en)	2024-11-28	Composition for the prevention or treatment of neurodegenerative or motor neuron diseases comprising halofuginone as an active ingredient
US20040138145A1 (en)	2004-07-15	Application of intestinal biliary acid reuptake inhibitors for the prevention and treatment of alzheimer's disease
EP2412705B1 (en)	2014-05-07	Novel therapeutic agent for cognitive impairment
EP3909568B1 (en)	2024-09-18	Prophylactic or therapeutic drug for neurodegenerative diseases
US6767898B2 (en)	2004-07-27	Methods for using specific saccharides for treating alzheimer's disease and other amyloidoses
WO2018195055A1 (en)	2018-10-25	Therapies for treating infantile spasms and other treatment-resistant epilepsies
KR100515554B1 (ko)	2005-09-20	알츠하이머병의 치료를 위한 판퀴논의 사용
CN107205973A (zh)	2017-09-26	用于预防或治疗神经变性疾病的含有Ramalin的组合物
WO1999007412A1 (fr)	1999-02-18	Remedes contre les maladies associees a la resorption osseuse

Legal Events

Date	Code	Title	Description
2005-06-10	PA0105	International application	Patent event date: 20050610 Patent event code: PA01051R01D Comment text: International Patent Application
2005-08-26	PG1501	Laying open of application
2010-01-05	PC1203	Withdrawal of no request for examination
2010-01-05	WITN	Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid