KR102094061B1 - Method of anti-wrinkle and Anti-aging cosmetics compositions using colloidal gold - Google Patents

Abstract

The present invention relates to a method for preparing a cosmetic composition, and more specifically, a gold colloid that contains gold colloid as an active ingredient, and has various effects such as skin improvement, elasticity enhancement, and moisturizing effect, thereby preventing skin aging and improving wrinkles. As a method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using,
Specific solution means of the present invention,
"In preparing a cosmetic composition containing 1 to 20% by weight of gold colloid of 25-60nm size,
After adding 0.4 to 0.7 g of dextrin to 1 liter of purified water and stirring for 5 minutes, add 3 to 7 ml of an aqueous solution containing 1% by weight of Gold Chloride, while stirring and heating to 90 to 100 ° C to produce a mixed solution.
While maintaining the resulting mixed solution at 90 to 100 ° C., after mixing 0.2 to 1 g of an aqueous solution containing 5% by weight of sodium carbonate, stir until the mixed solution turns red to a size of 25 to 60 nm. A method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using a gold colloid, which is formed by generating a gold colloid,
A method of manufacturing a cosmetic composition for improving wrinkles and preventing aging using gold colloid, characterized in that a peptide having an excellent effect on wrinkle improvement and skin elasticity is added to the cosmetic composition,
The peptide is acetyl hexapeptide-3 (Acetyl Hexapeptide-3), palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tetrapeptide-3 -3), Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Palmitoyl Oligopeptide, Octapeptide-2, Copper Tree Method for producing wrinkle improvement and anti-aging cosmetic composition using gold colloid, characterized by adding 0.001 to 0.1% by weight of peptide to gold colloid by selecting one or more of peptide-1 (Copper tripeptide-1) and ,
5 ~ 30% by weight of cosmetic oil, wax or butter and 3 ~ 10% by selecting one or more of cosmetic oil, wax, or butter to provide nutrition to the skin and moisturize the skin and form a protective film on the cosmetic composition Method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using gold colloid, characterized by adding 0.1% to 3% by weight of an emulsifier for cosmetics, and
The cosmetic oil, wax, or butter is jojoba oil, almond oil, avocado oil, evening primrose oil, calendula oil, camellia oil, coconut oil, castor oil, beads wax, olive oil wax, aloe wax, shea butter, camellia Butter, aloe butter is added by selecting any one or more or more, and the emulsifier for cosmetics is cetyl alcohol, triethanolamine, glyceryl stearate, polyethylensorbitan stearate, sorbitan stearate, butanediol, glycerin, laur It is added by selecting any one or more of ric acid, palmitic acid, and ceramide, and one or more of xanthan gum, carbomer, carboxymethylcellulose, hydroxyethylcellulose, and hyuronic acid as the cosmetic thickener Wrinkles using a gold colloid, characterized in that added by selecting Improvement and anti-aging cosmetic composition manufacturing method "
According to the present invention, by mixing the gold colloid of the present invention in general cosmetics, for example, skin, lotion, etc., it can exert effects such as anti-inflammatory, wrinkle improvement, skin regeneration, etc., which are the efficacy of gold specified in Donguibogam, and consist of gold colloid. As it provides the effect of preventing aging by removing impurities and dead skin cells by giving the skin elasticity without causing irritation and injury to the skin.

Description

Method of anti-wrinkle and anti-aging cosmetics compositions using colloidal gold}

The present invention relates to a method for preparing a cosmetic composition, and more specifically, a gold colloid that contains gold colloid as an active ingredient, and has various effects such as skin improvement, elasticity enhancement, and moisturizing effect, thereby preventing skin aging and improving wrinkles. It relates to a method for manufacturing a cosmetic composition for improving wrinkles and preventing aging.

The skin is the largest organ of our body, which occupies about 16% of the volume of our body and is directly in contact with the external environment, and is a lot of deadly harmful factors that try to get into the body. It plays an important protective role to protect the human body from.

However, as we age, our skin is damaged due to natural aging, various contaminants, strong ultraviolet rays, stress, and nutritional deficiencies, which causes the skin's original functions to fail to function properly, resulting in wrinkles on the skin. Skin aging such as formation, loss of elasticity, and keratinization occurs. In addition, a decrease in moisturizing power of the skin and a slowing of the keratinization rate of the skin are also caused by skin aging. That is, since the amount of collagen, mucopolysaccharide, and hyaluronic acid in the dermis matrix, which plays an important role in maintaining skin elasticity with age, decreases and the amount of insoluble collagen increases, the dermis retains moisture in the skin. It becomes difficult to do, and the skin becomes rough. In addition, the function of the sebaceous glands and sweat glands is also reduced, so the amount of sebum and sweat gradually decreases, and the sebaceous membrane is not properly produced, so the protective function for moisturizing the skin is lost, and eventually the skin is dry and loses transparency. , The elasticity of skin protein is reduced and wrinkles are created. In other words, the loss of moisturizing power of the skin is a major symptom of aging, along with a decrease in skin elasticity and wrinkle formation, and is closely related.

In addition, it is known that when human skin cells are exposed to ultraviolet rays (Y _δ -B, Y _δ -A), wrinkles are induced due to the generation of free radicals, which are the main causes of skin damage. Among the structures of the skin, collagen fibers and elastic fibers (elastin) present in the dermal layer are the main proteins that govern the elasticity of the skin. The biosynthesis of collagen fibers receives internal and external nutrients from the skin, and internally, natural aging (reduction of estrogen) causes a decrease in cellular activity, leading to a decrease in collagen fibers. As an external factor, free radicals (free radical type) generated due to excessive irradiation of ultraviolet rays and stress react with -SH groups of proteins to inhibit the activity of enzymes or to degrade collagen, elastin, etc. (Metalloproteinases: MMPS) ) To increase the expression of collagenase, which causes the aging phenomenon to reduce wrinkles and elasticity of the skin.

To date, in order to suppress skin aging or to slow down the progression rate, a cosmetic or skin protectant containing various skin protection ingredients such as retinol, retinoid, vitamin X, flavonoid, and tocopherol has been developed. In the final formulation, the potency is low, so its efficacy is slight, and skin irritation is severe.

In recent years, due to the skin irritation problem of these raw materials, many cosmetics have been developed using natural vegetable raw materials that are safer and have no irritation to the skin. In particular, in Korea, many cosmetics using natural herbal ingredients have been developed. For this reason, since natural herbal ingredients have been used in the private sector for a long time, safety and effectiveness have already been secured. Because there is.

Among them, according to Donguibogam, gold has the effect of stabilizing the nerve when it is very surprised and has a detoxifying effect by absorbing and releasing harmful substances in the human body. It is shown. Therefore, it is expected that applying this gold effect can produce soaps or cosmetics with the effect of alleviating atopy or skin inflammation.

In addition, the gold effect discovered by the advancement of modern science slows down collagen consumption and elastin collapse and prevents the skin from sagging, and stimulates cell growth in the base layer to regenerate healthy, elastic skin to help lifting. It is known to give. In addition, the fine gold of fine particles adsorbs and removes heavy metals or various pollutants that cause skin aging, and is also effective in removing waste products present in pores. In addition, it promotes the secretion of hormones, which helps cell activation, prevents skin aging, and helps prevent wrinkles and remove freckles. Lastly, it helps to relieve various inflammations and acne by purifying the skin of gold.

Therefore, it has emerged to develop cosmetics that allow gold to be efficiently absorbed into the skin, and the price of gold is high enough to use gold in an amount sufficient to expect the efficacy of gold in commercially available gold-containing cosmetics. However, there is a limit to applying it to cosmetics. In addition, cosmetic products containing gold that are currently on the market use a very small amount of gold in the form of gold foil powder, so that gold penetrates the skin and exhibits the effect of gold, which has a problem in particle size.

Korean Patent Registration No. 10-0904552 Korean Patent Publication No. 10-2015-0066826 Korean Patent Publication No. 10-2010-0132514 Korean Patent Publication No. 10-2014-0027947

In the present invention, by manufacturing a gold colloid and using it as a main raw material for cosmetics, there are no skin side effects, and wrinkle improvement and anti-aging cosmetics using gold colloid having anti-aging effects such as wrinkle improvement and anti-aging, which have excellent skin improvement, elasticity enhancement and moisturizing effect. To develop,

In addition, the nano-colloidal gold colloid is added to cosmetics, and when rubbed into the skin, it exhibits a complex skin improvement effect with little anti-inflammatory action, no skin regeneration effect and no skin irritation, and also provides the present invention suitable for sensitive skin such as atopic skin. The purpose is.

Specific solution means to achieve the above object,

"In preparing a cosmetic composition containing 1 to 20% by weight of gold colloid of 25-60nm size,
After adding 0.4 to 0.7 g of dextrin to 1 liter of purified water and stirring for 5 minutes, add 3 to 7 ml of an aqueous solution containing 1% by weight of Gold Chloride, while stirring and heating to 90 to 100 ° C to produce a mixed solution.
While maintaining the resulting mixed solution at 90 to 100 ° C., after mixing 0.2 to 1 g of an aqueous solution containing 5% by weight of sodium carbonate, stir until the mixed solution turns red to a size of 25 to 60 nm. A method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using a gold colloid, which is formed by generating a gold colloid,

The cosmetic composition for wrinkle improvement and anti-aging using gold colloid, characterized in that by adding a peptide having an excellent effect on wrinkle improvement and skin elasticity to the cosmetic composition,

The peptide is acetyl hexapeptide-3 (Acetyl Hexapeptide-3), palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tetrapeptide-3 -3), Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Palmitoyl Oligopeptide, Octapeptide-2, Copper Tree Method for producing wrinkle improvement and anti-aging cosmetic composition using gold colloid, characterized in that 0.001 to 0.1% by weight of peptide is added to a gold colloid by selecting one or more of peptide-1 (Copper tripeptide-1) and ,

 5 ~ 30% by weight of cosmetic oil, wax or butter and 3 ~ 10% by selecting any one or more of cosmetic oil, wax or butter for nourishing the skin and moisturizing the skin and forming a protective film on the cosmetic composition Method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using gold colloid, characterized by adding 0.1% to 3% by weight of an emulsifier for cosmetics, and

The cosmetic oil, wax, or butter is jojoba oil, almond oil, avocado oil, evening primrose oil, calendula oil, camellia oil, coconut oil, castor oil, beads wax, olive oil wax, aloe wax, shea butter, camellia Butter, aloe butter is added by selecting any one or more or more, and the emulsifier for cosmetics is cetyl alcohol, triethanolamine, glyceryl stearate, polyethylensorbitan stearate, sorbitan stearate, butanediol, glycerin, laur It is added by selecting any one or more of ric acid, palmitic acid, and ceramide, and one or more of xanthan gum, carbomer, carboxymethylcellulose, hydroxyethylcellulose, and hyuronic acid as the cosmetic thickener Note using gold colloid, characterized in that added by selecting It can achieve improvement and anti-aging cosmetic composition preparation method, "the above-mentioned object by a structure characteristics.

According to the present invention, it is possible to exert effects such as anti-inflammatory, wrinkle improvement, skin regeneration, etc., which are the efficacy of gold specified in Donguibogam by mixing the gold colloid of the present invention with general cosmetics, for example, skin, lotion, etc. As it provides the effect of preventing aging by removing impurities and dead skin cells by giving the skin elasticity without causing irritation and injury to the skin.

1 is an enlarged photograph of a gold colloid using a transmission electron microscope in a method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using a gold colloid according to the present invention,
Figure 2 is a photograph of the wrinkles around the eyes taken for 12 weeks before and after applying the composition prepared by the method of manufacturing a cosmetic composition for improving wrinkles and preventing aging using gold colloid according to the present invention.

Specific structural or functional descriptions of the embodiments according to the concept of the present invention disclosed in this specification are exemplified only for the purpose of illustrating the embodiments according to the concept of the present invention, and the embodiments according to the concept of the present invention Since it is possible to make various changes and have various forms, it includes all changes, equivalents, or substitutes included in the spirit and scope of the present invention, and terms or words used in the specification and claims are conventional or dictionary Not to be construed as being limited to meaning, the inventor can, on the basis that he can appropriately define the concept of terms in order to explain his or her invention in the best way, meaning and concept consistent with the technical idea of the present invention Should be interpreted as Therefore, the embodiments shown in the specification and drawings of the present invention are merely the most preferred embodiments of the present invention and do not represent all the technical spirit of the present invention, and are replaced at the time of filing of the present invention. It should be understood that various equivalents and variations that can be made are possible or possible.

In addition, unless defined otherwise in the specification of the present invention, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person skilled in the art to which the present invention pertains. Have Terms such as those defined in a commonly used dictionary should be interpreted as having meanings consistent with meanings in the context of related technologies, and should not be interpreted as ideal or excessively formal meanings unless explicitly defined herein. Does not.

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Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings.
1 is an enlarged picture of a gold colloid using a transmission electron microscope in the method for manufacturing wrinkle improvement and anti-aging cosmetic composition using gold colloid of the present invention, and FIG. 2 is a cosmetic composition for improving wrinkle and anti-aging using gold colloid of the present invention This is a photograph of the wrinkles around the eyes that were taken for 12 weeks before and after applying the composition prepared by the manufacturing method around the eyes.

The present invention is intended to apply the efficacy of gold to cosmetics by mixing gold colloid with existing cosmetics, which is a problem caused by simply using gold as powder or powder. For example, skin by mixing gold powder or powder in skin, lotion, etc. This is to solve the roughness of absorption and touch and to make the skin colloidal and to exert the softness of tactile sensation at the same time by making the gold colloid.
In preparing a cosmetic composition containing 1 to 20% by weight of gold colloid of 25-60nm size,
After adding 0.4 to 0.7 g of dextrin to 1 liter of purified water and stirring for 5 minutes, add 3 to 7 ml of an aqueous solution containing 1% by weight of Gold Chloride, while stirring and heating to 90 to 100 ° C to produce a mixed solution.
While maintaining the resulting mixed solution at 90 to 100 ° C., after mixing 0.2 to 1 g of an aqueous solution containing 5% by weight of sodium carbonate, stir until the mixed solution turns red to a size of 25 to 60 nm. This is done by creating a gold colloid.

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1 is an enlarged photo of a gold colloid using a transmission electron microscope, and shows that the size of the formed gold particles is approximately 25-60 nm.

Preferably, it is made by adding a peptide when preparing the cosmetic composition,

The peptide is acetyl hexapeptide-3 (Acetyl Hexapeptide-3), palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tetrapeptide-3 -3), Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Palmitoyl Oligopeptide, Octapeptide-2, Copper Tree Peptide-1 (Copper tripeptide-1) is selected from any one or more than one, and 0.001 to 0.1% by weight of the peptide is added to the gold colloid.

That is, the acetyl hexapeptide-3 (Acetyl Hexapeptide-3), palmitoyl pentapeptide-4, palmitoyl tetrapeptide-3, palmitoyl oligopeptide (Palmitoly Oligopeptide) It can be effective in improving wrinkles,

The palmitoyl tripeptide-1 and copper tripeptide-1 exert their effects on skin improvement,

The octapeptide-2 (Octapeptide-2) is effective in improving hair, and other peptides are also capable of effectively exerting skin and improving wrinkles.

5 to 30% by weight of cosmetic oil, wax or butter and 3 or more by selecting any one or more of cosmetic oil, wax or butter to provide nutrition to the cosmetic composition prepared as described above, moisturize skin and form a protective film. Cosmetics are prepared by adding ~ 10% by weight of emulsifiers for cosmetics and 0.1 ~ 3% by weight of thickeners, or by mixing 1 ~ 20% of the gold colloid of the present invention in general cosmetics such as skin, lotion, etc. It can exert effects such as anti-inflammatory, wrinkle improvement, skin regeneration, etc., which are the effects of gold, and it is made of gold colloid. It provides the effect of preventing aging.

The cosmetic oil, wax, or butter is jojoba oil, almond oil, avocado oil, evening primrose oil, calendula oil, camellia oil, coconut oil, castor oil, beads wax, olive oil wax, aloe wax, shea butter, camellia Butter, aloe butter is selected from any one or more, and added.

The emulsifier for cosmetics is cetyl alcohol, triethanolamine, glyceryl stearate, polyethylene sorbitan stearate, sorbitan stearate, butanediol, glycerin, lauric acid, palmitic acid, ceramide, or one or more of them are added Will

As the thickener for cosmetics, xanthan gum, carbomer, carboxymethylcellulose, hydroxyethylcellulose, or one or more of hyuronic acid is selected and added.

Looking at the test example for the wrinkle improvement rate of the present invention as described above,

[Test Example 1: wrinkle improvement rate]

Purified water 65g, gold colloid 15g, acetyl hexapeptide-3 0.02g, acetyl octapeptide-3 0.02g, shea butter 5g, olive emulsifying wax 4g, butanediol 4g, glycerin 3g, polyethylene sorbitan stearate 3g, xanthan gum 0.96 Looking at the case of applying wrinkle-prepared and anti-aging cosmetics prepared with g,

Specifically, using a facial diagnostic device, three subjects (I, II, and III) were evaluated for improvement in eye wrinkles for 12 weeks by applying an appropriate amount around the eye area twice a day after washing in the morning and evening. 2 is a photograph of the wrinkles of the eyes, Table 1 shows the size of the wrinkles, and Table 2 shows the wrinkle improvement rate as a result of measuring the wrinkles.

As shown in Figure 2, Table 1, and Table 2, as a result of comparing the degree of wrinkles before and after the use of the above-mentioned prepared cosmetic products with a four-week time difference, the present invention shows a significant difference before and after use and has excellent effect on wrinkle improvement It was confirmed that there is.

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As described above, although the present invention has been described with limited embodiments and drawings, the present invention is not limited to the above embodiments, and the contents described above by those skilled in the art to which the present invention pertains Of course, various modifications and variations may be possible.

Therefore, the technical idea in the present invention should be grasped by the claims described below, but it will be apparent that all equivalent or equivalent modifications fall within the scope of the technical idea of the present invention.

Claims (5)

In preparing a cosmetic composition containing 1 to 20% by weight of gold colloid of 25-60nm size,
After adding 0.4 to 0.7 g of dextrin to 1 liter of purified water and stirring for 5 minutes, add 3 to 7 ml of an aqueous solution containing 1% by weight of Gold Chloride, while stirring and heating to 90 to 100 ° C to produce a mixed solution.
While maintaining the resulting mixed solution at 90 to 100 ° C., after mixing 0.2 to 1 g of an aqueous solution containing 5% by weight of sodium carbonate, stir until the mixed solution turns red to a size of 25 to 60 nm. A method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using a gold colloid, which comprises a gold colloid.
According to claim 1,
A method for manufacturing a cosmetic composition for improving wrinkles and preventing aging using a gold colloid, characterized by adding a peptide having an excellent effect on wrinkle improvement and skin elasticity to the cosmetic composition.
According to claim 2,
The peptide is acetyl hexapeptide-3 (Acetyl Hexapeptide-3), palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tetrapeptide-3 -3), Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Palmitoyl Oligopeptide, Octapeptide-2, Copper Tree Method for manufacturing wrinkle improvement and anti-aging cosmetic composition using gold colloid, characterized in that 0.001 to 0.1% by weight of peptide is added to gold colloid by selecting any one or more of peptide 1 (Copper tripeptide-1).
The method of claim 1 or 2,
5 ~ 30% by weight of cosmetic oil, wax or butter and 3 ~ 10% by selecting any one or more of cosmetic oil, wax or butter for nourishing the skin and moisturizing the skin and forming a protective film on the cosmetic composition Method for manufacturing wrinkle improvement and anti-aging cosmetic composition using gold colloid, characterized by adding 0.1% to 3% by weight of an emulsifier for cosmetics.
The method of claim 4,
The cosmetic oil, wax, or butter is jojoba oil, almond oil, avocado oil, evening primrose oil, calendula oil, camellia oil, coconut oil, castor oil, beads wax, olive oil wax, aloe wax, shea butter, camellia Butter, aloe butter is selected from any one or more, and added.
The emulsifier for cosmetics is cetyl alcohol, triethanolamine, glyceryl stearate, polyethylene sorbitan stearate, sorbitan stearate, butanediol, glycerin, lauric acid, palmitic acid, ceramide, or one or more of them are added Will
Cosmetic composition for wrinkle improvement and anti-aging using gold colloid, characterized in that one or more of xanthan gum, carbomer, carboxymethylcellulose, hydroxyethylcellulose, and hyaluronic acid is added as the thickener for cosmetics. Manufacturing method.

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