KR101215353B1 - Fluid viscosity measuring device and method of measuring fluid-viscosity - Google Patents

Abstract

The present invention relates to a viscosity measuring device and a viscosity measuring method capable of measuring the viscosity of a fluid sample.
The fluid viscosity measuring device of the present invention includes a first inlet for injecting a first fluid for which viscosity is to be measured, and a second for injecting a second fluid that is incompatible with the first fluid and which has a viscosity. A fluid injection part in which an injection hole is formed; And a channel array connected to the fluid injection unit and having a plurality of channels having the same unit cross-sectional area and spaced apart from each other in a direction crossing the flow direction of the first fluid and the second fluid.

Description

Fluid viscosity measuring device and method of measuring fluid-viscosity

The present invention relates to a viscosity measuring device and a viscosity measuring method. More specifically, the present invention relates to a fluid viscosity measuring device and a fluid viscosity measuring method capable of measuring the viscosity of a fluid sample.

Fluid has a property of resisting flow when a fluid flows. This property is called viscosity, and the magnitude of this viscosity is called viscosity.

On the other hand, measuring the physical properties of materials used in the modern industrial field is recognized as an important task. Among them, fluids such as oil and blood are more important properties than other properties among physical properties. For this reason, measuring the viscosity of a fluid is a prerequisite for using samples in fluid form.

Generally, a fluid viscosity measuring device for measuring the viscosity of a fluid such as blood is called a viscometer, and there are various types of viscometers that are currently used. There are various types of viscometers. To measure the viscosity by moving the spherical object, to measure the viscosity using the velocity at which the spherical object falls when the spherical object is dropped into a vertical tube filled with fluid, and when the object is rotated in a fluid-filled space There is a method of measuring the viscosity using the required torque.

However, in order to measure the viscosity by the conventional viscosity measurement method as described above, large equipment is required. In addition, in order to measure the exact viscosity of the fluid, several samples should be prepared and repeated measurements. The above-mentioned methods are complicated to prepare for the measurement and the measurement method is not easy.

 In addition, the conventional viscosity measurement method has a problem that requires a large amount of fluid for viscosity measurement. These problems limit the precise measurement of the viscosity of a fluid sample.

In addition, the conventional viscometer has a fear of error due to environmental changes when measuring the viscosity over a variety of shear rate.

On the other hand, in recent years, a fluid viscosity measuring device capable of measuring the viscosity of a fluid to be measured by comparing a reference fluid having a reference viscosity with a fluid to be measured, such as blood, has been developed. There is a limit to simple and stable measurement.

In addition, since blood contains red blood cells and platelets, unlike a fluid such as water, it is a non-Newtonian fluid in which the relationship between shear stress and strain is not constant, so that viscosity can be stably measured at various shear rates. A fluid viscosity measuring device is required.

The present invention has been made to solve the above-mentioned problems of the prior art, and an object thereof is to provide a viscosity measuring apparatus and a viscosity measuring method which can easily and simply measure the viscosity of a fluid sample.

It is also an object of the present invention to provide a fluid viscosity measuring apparatus and a viscosity measuring method capable of simply and stably measuring the viscosity for various shear rates in non-Newtonian fluids such as blood.

In order to solve the above problems, the present invention, the first inlet for injecting the first fluid to measure the viscosity (viscosity), and a second fluid that knows the viscosity and is not mixed with the first fluid A fluid injection unit in which a second injection hole is formed; And

And a channel array connected to the fluid injection unit and having a plurality of channels having the same unit cross-sectional area and spaced apart from each other in a direction crossing the flow direction of the first fluid and the second fluid. do.

The plurality of channels each have a rectangular cross-sectional shape and preferably has the same width and height.

The channel array may be provided in plural and disposed sequentially along the flow direction of the first fluid and the second fluid, and the channels of each channel array may have different unit cross-sectional areas. Preferably, a single channel is formed in communication with the outlet of the channel forming the channel and the inlet of the channel forming the next channel array.

Preferably, each of the channel arrays has the same number of channels, and the unit cross-sectional area of the channels of the channel arrays is increased or decreased stepwise with respect to the flow direction of the first fluid and the second fluid.

The channel array may include an increase pattern in which the unit cross-sectional area of the channels of the channel array is increased stepwise with respect to the flow direction of the first fluid and the second fluid, and the unit cross-sectional area of the channels of the channel array is the first fluid. And a reduction pattern arranged to decrease in stages with respect to the flow direction of the second fluid, so that the reduction pattern is arranged to have a symmetrical shape with respect to the connection site.

The viscosity of the first fluid may be measured by calculating a ratio of the number of channels of the channel array in which the first fluid and the second fluid flow, respectively, when the first fluid and the second fluid flow through the channel array. Can be.

The viscosity of the first fluid may be calculated as a function of the number of channels through which the first fluid and the second fluid flow through the channel array and the flow rates of the first fluid and the second fluid, The viscosity coefficient of the first fluid may be calculated by the following equation.

Where μ _A is the viscosity coefficient of the first fluid, μ _B is the viscosity coefficient of the second fluid, N _A is the number of channels through which the first fluid flows in the channel array, and N _B is the flow rate of the second fluid in the channel array. Number of channels, Q _A : flow rate of the first fluid, Q _B : flow rate of the second fluid)

The first fluid includes a non-Newtonian fluid whose viscosity varies according to a shear rate, and the second fluid includes a Newtonian fluid having a constant viscosity regardless of the shear rate. It may include, wherein the first fluid is blood (Blood), the second fluid is preferably phosphate buffered saline (PBS).

As another embodiment, the first fluid and the second fluid may include Newtonian fluids having a constant viscosity regardless of the shear rate.

In addition, it is preferable that a surface tension ratio of the first fluid and the second fluid is 2 or less.

The apparatus may further include a fluid guide unit connected between the fluid injection unit and the channel array and configured to guide the first fluid and the second fluid to form one movement path.

In another aspect, the present invention provides a step of providing a channel array in which a plurality of channels having the same unit cross-sectional area is spaced apart, the first fluid and the viscosity to be measured viscosity is not mixed with the first fluid Injecting a second fluid into the channel array at a constant flow rate, calculating a number of channels of the channel array through which the first fluid and the second fluid flow, and calculating a ratio of the number to calculate the ratio of the first fluid It provides a fluid viscosity measurement method comprising the; measuring the viscosity of the fluid.

The viscosity of the first fluid may be calculated as a function of the number of channels through which the first fluid and the second fluid flow through the channel array and the flow rates of the first fluid and the second fluid, Viscosity coefficient of the first fluid is preferably calculated by the following equation.

According to the present invention, in order to measure the viscosity of the sample flowing through the channel, by the method of counting the number of channels occupied by the sample in each stage channel array, it is possible to easily and simply measure the viscosity, as well as Newtonian fluid In particular, it is very easy and simple to measure the viscosity of non-Newtonian fluids that are difficult and complex in viscosity measurement.

In addition, according to the present invention, by forming a multi-stage channel array having a different unit cross-sectional area, the viscosity can be measured for a variety of shear rates of the fluid.

In addition, in the fluid viscosity measuring apparatus of the present invention, the channel array is symmetrically disposed with respect to the central portion of the channel, so that the same shear rate can be repeated in real time when measuring the viscosity of the fluid, and the same shear rate is the same. It is possible to check whether the viscosity is calculated, which has the effect of increasing the reliability of the device.

In addition, the present invention has the advantage that the structure is simple and simple, anyone can easily configure the device and use it to measure the viscosity of the fluid.

1 is a configuration diagram schematically showing a fluid viscosity measuring apparatus according to an embodiment of the present invention.
FIG. 2 is an enlarged view of part X of FIG. 1.
3 is a cross-sectional view taken along line II ′ of FIG. 2.
4 is a cross-sectional view taken along line II-II ′ of FIG. 2.
5 is a view for explaining the principle of measuring the viscosity of the fluid using the fluid viscosity measuring device of the present invention.
6 is a view showing the interface pattern of the fluid in the experiment using the fluid viscosity measuring device according to an embodiment of the present invention.
7 is a schematic view showing a fluid viscosity measuring apparatus according to another embodiment of the present invention.
8 is a configuration diagram schematically showing a fluid viscosity measuring device according to another embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the drawings, the same reference numerals are used to designate the same or similar components throughout the drawings. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

1 is a schematic view showing a fluid viscosity measuring apparatus according to an embodiment of the present invention, FIG. 2 is an enlarged view of a portion X of FIG. 1, and FIGS. 3 and 4 are Ⅰ-I of FIG. 2, respectively. Sectional drawing according to the line and II-II.

As shown in Figure 1 to 2, the fluid viscosity measuring apparatus according to an embodiment of the present invention is a substrate 3, a structure 3 of a transparent material bonded to the substrate (1), etc. It may be configured as. Here, the structure 3 constituting the fluid viscosity measuring device may include a fluid inlet 10, a fluid guide 20, the channel 30 and the fluid outlet 40.

The board | substrate 1 is manufactured in the form of the flat plate which consists of glass etc., for example. The structure 3 may be made of PDMS or the like, for example, and the structure 3 may be firmly fixed to the substrate 1 by using plasma bonding.

The fluid inlet 10 may include a first inlet 11 for injecting a first fluid A for measuring viscosity and a second inlet for injecting a second fluid B having a known viscosity. (12) are formed respectively.

Here, the second fluid B, whose viscosity is already known, is a fluid which is not mixed with the first fluid A, and uses a Newtonian Fluid having a constant viscosity regardless of the shear rate. For example, when the first fluid A is a non-Newtonian fluid whose viscosity changes with shear rate, for example blood, the second fluid B is phosphate buffered with Newtonian behavior. It is preferable to use saline (Phosphate buffered saline (PBS)). In addition, when the first fluid A is a Newtonian fluid having a constant viscosity regardless of the shear rate, for example, SDS solutions, the second fluid B is ultrapure water that performs Newtonian behavior. Is preferably used. That is, according to the fluid viscosity measuring apparatus according to the present invention, the viscosity of the fluid to be measured is irrespective of whether the fluid to be measured is a Newtonian fluid having a constant viscosity regardless of the shear rate or a non-Newtonian fluid whose viscosity changes according to the shear rate. Measurement is possible.

Table 1 below shows the test results of the interface stability test between the first fluid (A) and the second fluid (B).

Solution Surface tension (mN / m) BoundaryResults A B A B ratio Isopropanol (IPA) Mineral 23.00 32.50 1.41 Stable Dl water Mineral 72.84 33 2.24 Unstable Dl water Dl water 72.84 72.84 1.00 Stable Grape oil Mineral 21.00 32.50 1.55 Stable Dl water grape oil 72.84 21.00 3.47 Unstable Mineral oil Isopropanol (IPA) 32.50 23.00 1.41 Stable SDS Dl water 42.00 72.40 1.72 Stable Blood PBS 55.89 70.00 1.25 Stable

In order to measure the viscosity of the first fluid A using the fluid viscosity measuring apparatus according to the present invention, the first fluid A and the second fluid B must flow while maintaining the interface without being mixed with each other. Therefore, referring to the experimental results shown in Table 1, in order to maintain a stable interface between the first fluid (A) and the second fluid (B), the surface tension ratio of the first fluid (A) and the second fluid (B) ( It is preferable to select the second fluid B so that the surface tension ratio can be satisfied to 2 or less.

In the present embodiment, the first injection hole 11 and the second injection hole 12 is an example in which the cross-sectional area is formed gradually smaller from the inlet side to the outlet side, but is not limited to this, the first injection port 11 and the second injection hole It may be formed in the form of a straight tube having a constant cross-sectional area of (12).

In addition, although not shown in the drawings, a pump, a valve, or the like may be provided to inject the first fluid A and the second fluid B into the first inlet 11 and the second inlet 12, respectively. .

The fluid guide part 20 connects between an outlet where the first inlet 11 and the second inlet 12 of the fluid inlet 10 meet as one and an inlet of the channel unit 30 to be described later. A) and the second fluid (B) is introduced to guide to form a movement path. At this time, the first fluid A and the second fluid B are moved through the fluid guide part 20 in a non-mixed state. The outlet of the fluid guide portion 20 is connected to the inlet of the channel portion 30.

The channel portion 30 is configured by alternately arranging the channel array 33 and the single channel 34 with respect to the flow direction of the fluids A and B. The first fluid A and the second fluid B introduced into the channel part 30 through the fluid guide part 20 alternately flow between the channel array 33 and the single channel 34.

In the channel array 33, a plurality of channels 35 having the same unit cross-sectional area are spaced apart from each other in a direction intersecting with a flow direction of the first fluid A and the second fluid B. The channel array 33 is provided in plurality and sequentially disposed along the moving direction of the fluids A and B, and the fluids A and B introduced into the inlet of each channel array 33 are corresponding to the channel array 33. It flows out of the channel 35 forming the exit through the exit. The channel 35 constituting the channel array 33 is preferably provided in the same number for each channel array 33, but it is not necessary that each stage channel array 33 has the same number of channels 35. If necessary, the number of channels 35 provided in each stage channel array 33 may be different.

The single channel 34 is arranged between the channel arrays 33 which are sequentially arranged along the direction of movement of the fluids A and B. In other words, the single channel 34 is formed in such a manner that the outlet of the channel array 33 in the previous stage and the inlet of the channel array 33 in the next stage communicate with each other. With this structure, the fluids A and B passing through the channel array 33 in the previous stage are introduced into the channel array 33 in the next stage via the single channel 34.

The channel 35 constituting each stage channel array 33 has a unit cross-sectional area corresponding to the flow area in which fluids A and B flow, and the channels 35 constituting the channel array 33 in a specific stage are mutually different. Have the same cross-sectional area. The sum of the cross-sectional areas of the respective channels 35 constituting the channel array 33 in a specific stage is the cross-sectional area of the corresponding channel array 33.

Each channel 35 constituting the channel array 33 of a particular step is preferably formed to have a rectangular cross-sectional shape having the same width (w) and height (h). When the cross-sectional shape of the channel 35 is formed as a rectangle, it is easy to bond the substrate 1 and the structure 3 to each other, and the cross-sectional area of each channel 35 can be easily realized. The single channel 34 can also be configured to have a rectangular cross section. However, the shape of the channel 35 and the single channel 34 constituting the channel array 33 is not limited to this and can be manufactured in any shape.

The channel array 33 is sequentially arranged along the flow direction of the fluids A and B, and the channels forming the channel arrays 33 for each stage are arranged to have various shear rates with respect to the flow directions of the fluids A and B. The unit cross-sectional area of 35 is formed to be changed. At this time, the unit cross-sectional area of each stage channel array 33 is preferably configured to increase or decrease step by step with respect to the flow direction of the fluid (A, B).

For example, the channel portion 30 is connected to the outlet of the fluid guide 20 and the unit cross-sectional area of the channel 35 forming the channel array 33 is increased stepwise with respect to the flow direction of the fluid (A, B) The unit cross-sectional area of the incremental pattern 31, which is connected to the outlet of the incremental pattern 31 and which is connected to the outlet of the incremental pattern 31 and forms the channel array 33, with respect to the flow direction of the fluids A and B in a stepwise manner. The reduced pattern 32 to be disposed may be configured to be connected and disposed. In this case, the shear rate decreases as the average speed decreases in the increase pattern 31 in which the unit cross-sectional area of the channel 35 increases, and in the decrease pattern 32 in which the cross-sectional area of the channel 35 gradually decreases. As increases, the shear rate increases. That is, the shear rate may be changed by changing the unit cross-sectional area of the channel 35 constituting the channel array 33 for each stage, and the viscosity of the fluid may be measured for various shear rates.

In addition, the channel portion 30 preferably has a symmetrical shape with respect to the center portion C to which the increase pattern 31 and the decrease pattern 32 are connected. This symmetrical structure enables a repeated experiment in real time for the same shear rate when measuring the viscosity of the fluid by implementing a decrease pattern or an increase pattern again after the increase in the shear rate according to the change in the unit cross-sectional area of the channel 35.

In this embodiment, the channel part 30 is arranged in the order of increasing pattern 31, decreasing pattern 32 with respect to the flow direction of the fluid (A, B) to illustrate a configuration having a symmetrical structure, but is not limited thereto. The channel unit 30 may not only be arranged in the order of the decreasing pattern 32 and the increasing pattern 31, but may be configured of only one of the increasing pattern 31 and the decreasing pattern 32.

The fluid outlet 40 is connected to the outlet of the channel part 30, and the outlet 41 is formed so that the first fluid A and the second fluid B that have passed through the channel part 30 flow out.

5 is a view for explaining the principle of measuring the viscosity of the fluid using the fluid viscosity measuring device of the present invention.

Although FIG. 5 illustrates the channel array 33 of several stages of the channel unit 30 to explain the principle of measuring the viscosity of the fluid, the same may be applied to the other channel array 33.

When the first fluid A and the second fluid B are injected through the first inlet 11 and the second inlet 12 at a constant flow rate, the first fluid A and the second fluid B are The mixture is moved to the channel portion 30 while passing through the fluid guide portion 20 without mixing. At this time, the first fluid (A) and the second fluid (B) is not intermixed with each other, the interface (S) is formed by the relative difference in viscosity.

In order to measure the viscosity of the first fluid A with respect to each shear rate according to the change in the cross-sectional area of the channel portion 30, first, in a section 1, a channel having a low aspect ratio, that is, a flow width w The velocity is constant in the direction, and considering the Poiseuille flow characteristic for the channel whose velocity changes only in the depth (h) direction, the relationship between the pressure drop P and the flow Q, P = R _{From f} Q, the relationship between the pressure drop P and the flow rate Q of each of the first fluid A and the second fluid B is expressed by Equations 1 and 2 below.

Here, since the pressure drop P of the first fluid A and the second fluid B is the same for the section 1, the equations (1) and (2) can be summarized as in equation (3).

Substituting the fluid resistance relation for the channel having the low aspect ratio represented by Equation 4 into Equation 3, Equation 5 below.

Wherein μ _A and μ _B are the viscosity coefficients of the first fluid A and the second fluid _B , respectively, and w _A and w _B are the flow widths of the first fluid A and the second fluid B, respectively. Q _A and Q _B are injection flow rates of the first fluid A and the second fluid B, respectively.

Since the channel length (L _A = L _B ), the depth (h _A = h _B ), and the width (w _A = w _B ) are the same in Equation 5, Equation 5 can be simply summarized as in Equation 6 below. .

Therefore, the viscosity coefficient μ _A of the first fluid A may be calculated by Equation 7 below.

According to Equation 7, according to the fluid viscosity measuring apparatus of the present invention, by simply counting the number of channels 35 through which the first fluid A and the second fluid B flow in the channel array 33. The viscosity of the 1st fluid A can be calculated.

On the other hand, the viscosity of the first fluid (A) can be measured for the other plurality of sections by the same procedure as described above. That is, the first fluid (A) with respect to the various shear rate according to the change in the width of the channel 35 constituting the channel array 33 arranged in the channel portion 30 in the flow direction of the fluid (A, B) The viscosity of can be measured.

The fluid A, B passing through the section ① passes through the single channel 34 without being mixed again and moves to the channel array 33 of the section ②. At this time, the first fluid A and the second fluid B flow without being mixed with each other. ② The number of channels 35 through which the first fluid A and the second fluid B flow in each section is ① the channel 35 through which the first fluid A and the second fluid B flow in the section ①. May differ from the number of. ② The fluid (A, B) introduced into the section flows under a shear rate determined according to the width of the channel 35 constituting the channel array 33, and has a viscosity according to the shear rate. ② Counting the number of channels 35 through which each fluid (A, B) flows in the channel array 33 of the section and substituting the equation (7) ② The viscosity of the first fluid (A) corresponding to the shear rate in the section Can be calculated.

As described above, the present invention may measure the viscosity of the first fluid A for various shear rates by adjusting the width w of the channels 35 constituting the channel array 33 for each step. The shear rate in the channel 35 of each stage channel array 33 can be represented by the following equation (8).

는 전단율, w는 채널(35)의 폭, h는 채널(35)의 높이, Q는 유체(A, B)의 주입 유량이며, w?h 인 경우

이 된다.At this time,

Is the shear rate, w is the width of the channel 35, h is the height of the channel 35, Q is the injection flow rate of the fluids (A, B),

.

Therefore, according to Equation 8, various shear rate conditions can be implemented by changing the width of the channel 35 of each channel array 33. Furthermore, the channel array 33 may be provided in the channel unit 30 as many as the shear rate condition to be implemented. For example, when ten channel arrays 33 having different widths of the channel 35 are provided in the channel portion 30, the fluid viscosity measuring apparatus according to the present invention may provide ten shear rate conditions. have.

On the other hand, if the first fluid (A) to be measured viscosity is a non-Newtonian fluid whose viscosity is changed according to the shear rate, this tendency is the injection flow rate (Q) of the first fluid (A) and the second fluid (B) When properly adjusted, viscosity can be measured for shear rate under various conditions. In addition, the fluid viscosity measuring device according to the present invention can continuously monitor the viscosity of the first fluid (A) to be measured viscosity.

6 is a view showing the interface pattern of the fluid in the experiment using the fluid viscosity measuring device according to an embodiment of the present invention.

As shown in FIG. 6, the first fluid A is a non-Newtonian fluid whose viscosity changes with shear rate, and the second fluid B is a Newtonian fluid having a constant viscosity regardless of the shear rate. Here, the first fluid (A) is blood (Blood), the second fluid (B) was tested by taking an example that the phosphate buffered saline (PBS).

According to the experimental results, the fluid viscosity measuring apparatus of the present invention has a fluid interface (S) due to the difference in viscosity between the first fluid (A) and the second fluid (B) is the wall of the channel 35 of the channel array 33 The flow widths of the fluids A and B can be calculated simply by counting the number of channels 35 through which the first fluid A and the second fluid B flow, respectively. In addition, since the channel portion 30 changes the average velocity of the fluid by varying the width of the channels 35 constituting each of the channel arrays 33 so that the channel portion 30 can have various shear rates, the viscosity of the fluid is varied for various shear rates. Simple and stable measurement

In addition, the fluid viscosity measuring apparatus of the present invention is capable of measuring the viscosity of not only blood but also various other fluids, and is particularly useful for a fluid whose viscosity varies greatly with respect to the shear rate.

In addition, the present experiment exemplifies an experiment for measuring the viscosity of a non-Newtonian fluid whose viscosity changes according to the shear rate, but is not limited to this, and also applies to the measurement of viscosity for a Newtonian fluid having a constant viscosity regardless of the shear rate. It is possible.

7 is a schematic view showing a fluid viscosity measuring apparatus according to another embodiment of the present invention.

As shown in FIG. 7, the fluid viscosity measuring device according to another embodiment of the present invention includes a fluid inlet 10, a fluid guide 20, a channel 30, a fluid outlet 40, and the like. The same as the embodiment of FIGS. 1 to 5 except for the shape of the channel part 30. Therefore, detailed descriptions of components that perform the same functions as the exemplary embodiment of FIGS. 1 to 5 will be omitted.

The channel portion 30 is connected to the outlet of the fluid guide portion 20 and is connected to the inlet of the fluid outlet 40. The channel portion 30 is configured such that the channel array 33 and the single channel 34 are alternately arranged, and the single channel 34 has a width approximately equal to the width of the channel array 33 of the previous stage 34a. ), A rear end portion 34c having a width approximately equal to the width of the channel array 33 of the next stage, and a front end portion 34a and a rear end portion 34c, which are substantially the same as the fluid guide portion 20. It may be composed of a stop 34b having a width.

The channels 35 constituting the channel array 33 for each stage are formed to have a different width so as to have various shear rates with respect to the flow direction of the first fluid A and the second fluid B. FIG. At this time, the channel 35 of each stage channel array 33 is configured to increase in width with respect to the flow direction of the fluid (A, B), but on the contrary, the channel 35 of each stage channel array 33 It can be configured to decrease the width step by step with respect to the flow direction of the fluid (A, B).

8 is a configuration diagram schematically showing a fluid viscosity measuring device according to another embodiment of the present invention.

As shown in FIG. 8, the fluid viscosity measuring device according to another embodiment of the present invention includes a fluid inlet 10, a fluid guide 20, a channel 30 and a fluid outlet 40. And the same as the embodiment of FIGS. 1 to 5 except for the shape of the channel part 30. Therefore, detailed descriptions of components that perform the same functions as the exemplary embodiment of FIGS. 1 to 5 will be omitted.

The channel portion 30 is connected to the outlet of the fluid guide portion 20 and is connected to the inlet of the fluid outlet 40. The channel unit 30 is configured such that the channel array 33 and the single channel 34 are alternately arranged.

The channels 35 constituting the channel array 33 for each stage are formed to have a different width so as to have various shear rates with respect to the flow direction of the first fluid A and the second fluid B. FIG. At this time, the channel 35 of each stage channel array 33 is configured to increase in width with respect to the flow direction of the fluid (A, B), but on the contrary, the channel 35 of each stage channel array 33 It can be configured to decrease the width step by step with respect to the flow direction of the fluid (A, B).

It will be apparent to those skilled in the art that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims. . Therefore, the embodiments disclosed in the present invention are not intended to limit the scope of the present invention but to limit the scope of the technical idea of the present invention. The protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the equivalent scope should be interpreted as being included in the scope of the present invention.

10: fluid inlet portion 11: the first inlet
12: second inlet 20: fluid guide portion
30 channel portion 31 increase pattern
32: reduction pattern 33: channel array
34: single channel 35: channel
40: fluid outlet

Claims (19)

A fluid injecting unit including a first inlet for injecting a first fluid for which viscosity is to be measured and a second inlet for injecting a second fluid having a viscosity and not mixed with the first fluid; And
And a channel array connected to the fluid injection unit and having a plurality of channels having the same unit cross-sectional area and spaced apart from each other in a direction crossing the flow direction of the first fluid and the second fluid. The method of claim 1,
And each of the plurality of channels has a rectangular cross-sectional shape. The method of claim 2,
And said plurality of channels each have the same width and height. 4. The method according to any one of claims 1 to 3,
The channel array may be provided in plural and sequentially disposed along a flow direction of the first fluid and the second fluid.
The channels in each channel array have different unit cross sections,
An apparatus for measuring fluid viscosity, wherein a single channel is formed between each channel array so that the outlet of the channel constituting the channel array of the previous stage and the inlet of the channel constituting the channel array of the next stage are formed. 5. The method of claim 4,
Said channel array each having an equal number of channels. 5. The method of claim 4,
And said channel array each having a different number of channels. 5. The method of claim 4,
And a unit cross-sectional area of the channels of the channel array increases or decreases stepwise with respect to the flow direction of the first fluid and the second fluid. 5. The method of claim 4,
The channel array,
An increase pattern disposed so that the unit cross-sectional area of the channels of the channel array increases stepwise with respect to the flow direction of the first fluid and the second fluid;
The unit cross-sectional area of the channel of the channel array is arranged so that the reduction pattern is arranged so as to decrease stepwise with respect to the flow direction of the first fluid and the second fluid,
And the increasing pattern and the decreasing pattern are arranged to have a symmetrical shape with respect to the connection site. 4. The method according to any one of claims 1 to 3,
Measuring the viscosity of the first fluid by calculating a ratio of the number of channels of the channel array through which the first fluid and the second fluid flow, respectively, when the first fluid and the second fluid flow through the channel array Fluid viscosity measuring device. 10. The method of claim 9,
The viscosity of the first fluid,
And a fluid viscosity measuring device calculated as a function of the number of channels through which the first fluid and the second fluid flow through the channel array and the flow rates of the first fluid and the second fluid. The method of claim 10,
The viscosity coefficient of the first fluid is a fluid viscosity measuring device is calculated by the following equation.

(here,
μ _A : Coefficient of viscosity of the first fluid
μ _B : Viscosity coefficient of the second fluid
N _A : Number of channels through which the first fluid flows in the channel array
N _B : Number of channels through which the second fluid flows in the channel array
Q _A : flow rate of the first fluid
Q _B : flow rate of the second fluid) The method of claim 1,
The first fluid includes a non-Newtonian fluid whose viscosity changes according to a shear rate, and the second fluid includes a Newtonian fluid having a constant viscosity regardless of the shear rate. Fluid viscosity measuring device comprising a. The method of claim 12,
Wherein said first fluid is blood and said second fluid is phosphate buffered saline (PBS). The method of claim 1,
Wherein said first fluid and said second fluid comprise Newtonian fluids having a constant viscosity regardless of shear rate. The method of claim 1,
And a surface tension ratio of the first fluid and the second fluid is 2 or less. The method of claim 1,
And a fluid guide part connected between the fluid injection part and the channel array and configured to guide the first fluid and the second fluid to form one movement path. Providing a channel array in which a plurality of channels having the same unit cross-sectional area are spaced apart from each other;
Injecting into said channel array at a constant flow rate a first fluid for which viscosity is to be measured and a second fluid that knows the viscosity and is not mixed with said first fluid; And
And calculating a number of channels of the channel array through which the first fluid and the second fluid flow, and calculating a ratio of the numbers to measure the viscosity of the first fluid. 18. The method of claim 17,
The viscosity of the first fluid,
And a method of measuring the fluid viscosity as a function of the number of channels through which the first fluid and the second fluid flow through the channel array and the flow rates of the first fluid and the second fluid. 19. The method of claim 18,
The viscosity coefficient of the first fluid is a fluid viscosity measurement method is calculated by the following equation.

(here,
μ _A : Coefficient of viscosity of the first fluid
μ _B : Viscosity coefficient of the second fluid
N _A : Number of channels through which the first fluid flows in the channel array
N _B : Number of channels through which the second fluid flows in the channel array
Q _A : flow rate of the first fluid
Q _B : flow rate of the second fluid)

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