KR100361623B1 - Apparatus for controlling of ion osmosis type inputting device of water heated for medicinal decoction - Google Patents

Abstract

The present invention relates to an iontophoretic drug administration device and a method for controlling the polarity inversion and administration time of the positive voltage and the negative voltage supplied to each pad of the iontophoretic drug administration device to obtain an optimal drug administration effect It is about.

A feature of the present invention is to combine the active electrode to a pad filled with ionized drugs, and to supply the ionic components of the drug into the skin by alternately supplying a positive current and a negative current to the active electrode while the pad is attached to the skin. An iontophoretic drug administration device, comprising: a polarity inversion unit for inverting a polarity of a current supplied to an active electrode; A current amount adjusting unit controlling an amount of current supplied to the active electrode; A time setting unit for the operator to set the total administration time and the target current amount arrival time; A current amount setting unit for setting a target current amount supplied to the active electrode by the operator; A timer for outputting time information; A switch for controlling an operation state; The timer is operated in synchronization with the input of the switch, and the positive current is supplied to the active electrode by the target current amount set in the current amount setting unit for half of the total administration time set in the time setting unit, and the time counted by the timer is If the time equals to half of the total administration time, the polarity inversion unit is controlled to invert the polarity of the current supplied to the active electrode, and then the amount of current less than the amount of current set by the operator in the active electrode for half of the total administration time. The invention includes a controller for controlling to supply a negative current.

The present invention has the advantage that the therapeutic effect can be maximized by allowing simultaneous administration of cations and anions via one pad. This effect is particularly useful for herbal medicines in which different types of medicines are used.

Description

Ion-induced drug administration device {APPARATUS FOR CONTROLLING OF ION OSMOSIS TYPE INPUTTING DEVICE OF WATER HEATED FOR MEDICINAL DECOCTION}

The present invention relates to an iontophoretic drug administering device and a control method thereof, and more particularly, to optimize the drug by controlling the polarity inversion and administration time of positive and negative voltages supplied to each pad of the iontophoretic drug administering device. The present invention relates to an iontophoretic drug administration device and a method of controlling the same, which provide an effect of administration and provide convenience for use.

In general, iontophoresis is a kind of active transdermal dosing method in which a direct current flows into an electrolyte containing an ionized drug to be administered so that an ionic drug component is penetrated into the skin by electrical repulsive force.

Conventional iontophoretic treatment devices typically include a battery and a simple current control circuit coupled with two electrodes, an active electrode and a dispersion electrode. The active electrode is filled with an electrolyte in which the drug to be administered is ionized, and the dispersion electrode is attached to the skin of a suitable area at least 9 cm away from the active electrode. The active electrode is made to flow a direct current of the same polarity as the drug to be administered to infiltrate the drug into the skin. For example, in the case of lidocaine hydrochloride, since the main component has a (+) charge in the aqueous solution, when 3% lidocaine hydrochloride is filled in the drug pad of the active electrode and energized by connecting a positive pole of direct current, Lidocaine, charged with +), can penetrate into the skin.

Iontophoresis has the following advantages over oral administration.

First, because it does not go through the digestive system does not cause digestive disorders, the drug can be administered to patients with digestive disorders.

Second, the drug is not destroyed because it does not go through the first pass of the liver in the metabolic process of the drug.

Third, relatively toxic drugs can be administered.

Fourth, it is advantageous for the treatment of local diseases because the drug to reach the local directly.

In addition, iontophoresis has the following advantages over injection.

First, painless dosing.

Second, there is little risk of infection or skin tissue damage.

Third, the drug is administered through a kind of strong protective film called skin, and only the drug in an ionized state is administered, so high sterilization and tablets are not required as injectable drugs. Therefore, the iontophoretic transdermal administration of herbal medicine is very advantageous in the reality that injections are not developed like herbal medicine.

Iontophoresis is for example several types of lidocaine hydrochloride, hydrocortisone derivatives, acetic acid, fluoride, penicillin, dexamethasone sodium phosphate, etc. It is used as a method of administering a medicinal drug through the skin.

However, according to the conventional iontophoretic drug administration device, the following problem (s) occurs.

That is, the conventional iontophoretic drug administering device has been mainly used to administer the medicine. Yangyang medicine is generally composed of a single component with a positive (+) charge or a negative (-) charge, so that only one polarity current needs to flow.

In order to administer a drug containing a positively charged drug and a negatively charged drug like a Chinese medicine using an iontophoretic drug administration device made for the purpose of administering a medicine, (-) The administration of the pole should be directly adjusted by the operator and the polarity inversion should be operated by the operator directly, causing inconvenience and waste of manpower.

Accordingly, the present invention is to solve such a problem (s), the object of the present invention is to set the time information to administer the drug and the amount of current supplied to the active electrode and the positive current and By alternately supplying a negative current, it is possible to automatically administer a cationic drug and an anionic drug without the operator's separate operation, to provide an iontophoretic drug administration device that maximizes the therapeutic effect.

In addition, another object of the present invention to provide an iontophoretic drug administration device that minimizes the irritation of the skin even when the drug of the cation and anion is administered at the same time.

In addition, another object of the present invention to provide a control method of the iontophoretic drug administration device for achieving the above objects.

1 is a state diagram of the iontophoretic drug administration device applied to the present invention,

2 is a schematic block diagram of an iontophoretic drug administration device according to the present invention,

3 is an operation flowchart showing the process of performing the iontophoretic drug administration device control method according to the present invention,

4 is a voltage waveform diagram supplied to the active electrode shown in FIG. 1 according to the present invention.

<Description of the code | symbol about the principal part of drawing>

100: skin 101, 103: pad

102: active electrode 104: dispersion electrode

105: power supply unit 106: switch

107: polarity inversion unit 108: voltage level control unit

109: time setting unit 110: timer

111: controller

A characteristic of the present invention for achieving the object (s) is, by combining the active electrode to the pad filled with ionized drugs, and by supplying the positive and negative current to the active electrode alternately with the pad attached to the skin An iontophoretic drug administration device for introducing an ion component of a drug into the skin, comprising: a polarity inversion unit for inverting a polarity of a current supplied to an active electrode; A current amount adjusting unit controlling an amount of current supplied to the active electrode; A time setting unit for the operator to set the total administration time and the target current amount arrival time; A current amount setting unit for setting a target current amount supplied to the active electrode by the operator; A timer for outputting time information; A switch for controlling an operation state; The timer is operated in synchronization with the input of the switch, and the positive current is supplied to the active electrode by the target current amount set in the current amount setting unit for half of the total administration time set in the time setting unit, and the time counted by the timer is If the time equals to half of the total administration time, the polarity inversion unit is controlled to invert the polarity of the current supplied to the active electrode, and then the amount of current less than the amount of current set by the operator in the active electrode for half of the total administration time. The invention includes a controller for controlling to supply a negative current.

Here, it is preferable that the amount of current of the negative current is approximately half of the amount of current with respect to the amount of current of the positive current.

Further, the operator sets the total administration time through the time setting section and the time until the current amount increases to reach the target current amount set by the current amount setting section; The controller linearly increases the amount of current so as to reach the target amount of current set by the amount of current setting section during the set target amount of current reaching time; Maintaining the target current amount for a time other than the time to reach the target current amount and the preset reduction time from the time corresponding to half of the total administration time; It is preferable to reduce the amount of current linearly until the amount of current becomes '0' from the target amount of current for a predetermined reduction time.

On the other hand, another feature of the present invention, by coupling the active electrode to the pad filled with the ionized drug, and by supplying the positive and negative current to the active electrode alternately while the pad is attached to the skin to supply the ionic components of the drug into the skin A method of controlling an iontophoretic drug administering device for introducing a device, comprising: setting a total administration time and a target current amount supplied to an active electrode; Counts time in synchronization with the operation start point; Supplying a positive current of a target current amount set to the active electrode during the cationic drug administration time corresponding to half of the total administration time; If the count time and the cationic drug administration time are the same, the polarity of the current supplied to the active electrode is reversed; It is to supply a negative current less than the target current set on the active electrode during the anion drug administration time corresponding to half of the total administration time.

Here, the total administration time and the time until the current amount increases to reach the target current amount set by the current amount setting unit are set, respectively; The positive current linearly increases the current amount to reach the target current amount during the set target current amount reaching time, and increases the target current amount for the remaining time except the target current amount reaching time and the preset reduction time from half of the total administration time. Maintains the current amount linearly until the current amount becomes '0' from the target current amount for a predetermined reduction time; The negative current linearly increases the current amount so as to reach approximately half of the target current amount during the set target current amount arrival time, and the target current amount arrival time and the preset reduction time are adjusted from the half of the total administration time. The current amount corresponding to about half of the target current amount is maintained for the remaining time, and the current amount is linearly decreased until the current amount becomes '0' from the current amount corresponding to about half of the target current amount during the preset reduction time. It is preferable.

Hereinafter, exemplary embodiment (s) of the present invention will be described in detail with reference to the accompanying drawings. First, in adding reference numerals to the elements of each drawing, it should be noted that the same elements are denoted by the same reference numerals as much as possible even if they are displayed on different drawings. In addition, in the following description there are shown a number of specific details, such as components of the specific circuit, which are provided only to help a more general understanding of the present invention that the present invention may be practiced without these specific details. It is self-evident to those of ordinary knowledge in Esau. In describing the present invention, when it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted.

Figure 1 shows the state of use of the iontophoretic drug administration device applied to the present invention, Figure 2 is a schematic block diagram of the iontophoretic drug administration device according to the present invention, Figure 3 according to the present invention The operation flow chart showing the process of performing the iontophoretic drug administration device control method is shown, Figure 4 shows the voltage waveform supplied to the active electrode shown in Figure 1 in accordance with the present invention.

Referring to the configuration of the present invention with reference to FIGS. 1 and 2, the pad 101 and the active electrode 102 filled with an electrolyte are attached to an unspecified portion of the body 100 to be treated, and are spaced at least 9 cm apart. The empty pad 103 and the dispersion electrode 104 are attached to the broken portion. Accordingly, ions having the same polarity as that applied to the active electrode 102 among the electrolyte filled in the pad 101 can be introduced into the skin 100.

On the other hand, the configuration of the present invention in more detail, the power supply unit 105 generates a DC voltage to be supplied to each electrode (active electrode 102 and the dispersion electrode 104) of the iontophoretic drug administration device.

The switch 106 is installed at a predetermined position of the device so that the operator can control the driving state of the iontophoretic drug administration device.

The polarity inversion unit 107 supplies a voltage of a certain polarity during the drug administration time of the first polarity set by the operator, and after the drug administration time of the first polarity has elapsed, each electrode (active electrode 102 and the dispersion electrode) Reverse the polarity of the voltage supplied to (104).

The current amount adjusting unit 108 controls the amount of current supplied to each electrode (the active electrode 102 and the dispersion electrode 104).

The time setting unit 109 is installed at a predetermined position of the device so that the operator can set the time to administer the drug to the patient.

The current amount setting unit 110 is installed at a predetermined position of the device so that the operator can set the amount of current to be supplied to the active electrode 102.

The timer 111 outputs time information.

The active electrode 102 and the dispersion electrode 104 have a predetermined polarity by the power supplied from the power supply unit 105 to introduce the electrolyte solution in the pad 101 into the skin.

The pads 101 and 103 are divided into an active electrode pad 101 and a dispersion electrode pad 103, and the active electrode pad 101 is filled with a drug to be administered in the form of an electrolyte, and a pad for the dispersion electrode. Numeral 103 becomes empty. In particular, the size of the dispersion electrode pad 103 is set to be approximately twice the area of the area of the active electrode pad 101.

The controller 112 generally controls the iontophoretic drug administering device. That is, the controller 112 supplies the positive current to the active electrode 102 as much as the value set by the operator through the current amount setting unit 110 during the cationic drug administration time set by the operator through the time setting unit 109. After the cationic drug administration time has elapsed, the polarity inversion unit 107 is controlled to invert the polarity of the current supplied to the active electrode 102 to a negative current, and at the same time, the voltage level control unit 108 is controlled to activate the active electrode 102. Reduce the amount of current supplied to by approximately half.

Referring to Figures 3 and 4 with respect to the operation of the present invention having such a configuration as follows.

The operator sets a time for initially administering the drug through the time setting unit 109. At this time, in setting the drug administration time, as shown in FIG. 4a, the drug of the cation may be first introduced, and then the drug of the anion may be set to be introduced, or as shown in FIG. It may be set to inject the drug of the cation. Since the difference between these methods is made in the same manner in the technical description of the present invention, in the description of the operation of the present invention, as shown in FIG. Shall be. In addition, a separate conversion switch may be further configured so that the operator can select drug administration of cation and drug administration of anion.

As the operator sets the drug administration time, as shown in FIG. 4A, the time of the region A in which the current increases and the time of the region B in which the current remains constant and the region C in which the current decreases. Each can be set. Such a setting method may be various, but for convenience, the following three conditions are set by the user so that the definition is made in each area.

First, target current amount

Second, the time until the target current amount is reached

Third, total administration time

At this time, the time of the C region where the amount of current decreases to become '0' is not set by the operator directly, but is fixed to '10 seconds'.

For example, if the target current is set to '6 mA', the time to reach the target current is set to '1 minute' and the total dose time is set to '20 minutes', the current amount of positive current gradually increases for 1 minute. Up to 6 mA, the current amount of 6 mA is maintained for 8 minutes and 50 seconds, then decreases for 10 seconds to reach 0 mA, then the polarity is switched and the current amount reaches 3 mA for 1 minute automatically for 8 minutes and 50 seconds It is maintained and then slowly decreases for 10 seconds to reach 0㎃.

Here, the area A is referred to as an "incremental area", the area B is referred to as a "holding area", and the area C is referred to as a "reduction area".

First, the operator sets the total time to administer the drug according to the type and component of the drug to be administered. Then, the time corresponding to the increased area of the time to administer the drug of the cation is set (S1). The time information thus set is stored in the controller 112.

Then, the operator sets the target current amount to be supplied to the active electrode 102 and the dispersion electrode 104 to administer the drug through the current amount setting unit 110 (S2). Then, the drug to be administered is filled in the active electrode pad 101 (S3).

Subsequently, the active electrode pad 101 and the active electrode 102 are attached to the affected part of the patient (S4), and the distributed electrode pad 103 and the distributed electrode 104 are attached to a point adjacent to the affected part (S5). When the switch 106 is turned on (S6), the controller 112 initializes the timer 111, starts counting (S7), and the DC voltage supplied from the power supply unit 105 is polarized according to the counted value. The amount of current flowing through the active electrode 102 and the dispersion electrode 104 is controlled by controlling the supply to the active electrode 102 and the dispersion electrode 104 through the whole 107 and the current amount adjusting unit 108 (S8). ). At this time, the current supplied to the active electrode 102 increases linearly to reach the amount of current set by the operator during the time of the increase area set by the operator. The current amount is maintained, and when the holding area elapses, the current amount linearly decreases during the reduction area set in the device itself, and the current amount becomes '0' when the cationic drug administration time elapses.

Here, the polarity inversion unit 107 is maintained in an initial state to supply a positive current to the active electrode 102, and to supply a negative current to the dispersion electrode 104. Accordingly, the drug of the cationic component in the electrolyte filled in the active electrode pad 101 is introduced into the skin 100. Then, the controller 112 compares whether the time counted by the timer 111 is equal to the time corresponding to half of the total administration time set by the operator, and if the counted time is the same as the cationic drug administration time (S9), the polarity The inversion unit 107 is controlled to invert the polarity of the current supplied to the active electrode 102 and the current supplied to the dispersion electrode 104. In addition, since supplying a large amount of current to the active electrode 102 increases skin irritation, the controller 112 controls the current amount adjusting unit 108 to supply the active electrode 102 and the dispersion electrode 104 to the present time. The amount of current to be reduced to approximately half the amount of current (S10).

Therefore, after the polarity is reversed, that is, when a negative current is supplied to the active electrode 102, the skin irritation can be minimized by reducing the amount of current to about half.

Thereafter, the controller 112 compares the time counted by the timer 111 with the total administration time set by the operator, and ends all operations when the counted time and the total administration time are the same (S11). Thus, the drug administration process is terminated.

As described above, although the specific embodiment (s) have been described in the detailed description of the present invention, various modifications are possible without departing from the scope of the present invention. Therefore, the scope of the present invention should not be limited to the described embodiment (s) but should be defined by the claims below and equivalents thereof.

As a result, according to the iontophoretic drug administration device according to the present invention the following advantage (s) occurs.

That is, by allowing the drug of the cation and anion to be simultaneously administered through one pad, the therapeutic effect is maximized. This effect is particularly useful for herbal medicines in which different types of medicines are used.

In addition, by reducing the level of negative voltage when reversing the polarity of the voltage supplied to the active electrode and the dispersion electrode, irritation of the skin can be minimized even when the drug of the positive and negative ions are administered simultaneously.

Claims (6)

An iontophoresis type for introducing an ionic component of the drug into the skin by coupling an active electrode to a pad filled with an ionized drug and alternately supplying a positive current and a negative current to the active electrode while the pad is attached to the skin. In the drug administration device: A polarity inversion unit for inverting the polarity of the current supplied to the active electrode; A current amount control unit controlling an amount of current supplied to the active electrode; A time setting unit for the operator to set the total administration time and the time to reach the target current amount; A current amount setting unit for the operator to set a target current amount supplied to the active electrode; A timer for outputting time information; A switch for controlling an operation state; And Operating the timer in synchronization with an input of the switch, supplying a positive current to the active electrode by the target current amount set by the current amount setting unit for a time corresponding to half of the total administration time set by the time setting unit, If the time counted by the timer is equal to a time equal to half of the total administration time, the polarity inversion unit is controlled to invert the polarity of the current supplied to the active electrode and then for a time corresponding to half of the total administration time. An iontophoretic drug administration device comprising a controller for controlling the supply of a negative current less than the current amount set by the operator to the active electrode. The method of claim 1, wherein the current amount of the negative current, An iontophoretic drug delivery device, characterized in that about the current amount of about half of the current amount of the positive current. The method of claim 1, The operator sets the total administration time and the time until the current amount increases until the target current amount set by the current amount setting unit is reached through the time setting unit; The controller linearly increases the amount of current so as to reach the target amount of current set by the current amount setting unit during the set amount of current reached; Maintaining the target current amount for a time other than the time to reach the target current amount and a predetermined reduction time from the time corresponding to half of the total administration time; And the current amount is linearly decreased until the current amount becomes '0' from the target current amount during the preset reduction time. delete delete delete