KR100281867B1 - 3-(비스-치환페닐메틸렌)옥신돌유도체 - Google Patents
3-(비스-치환페닐메틸렌)옥신돌유도체 Download PDFInfo
- Publication number
- KR100281867B1 KR100281867B1 KR1019970706430A KR19970706430A KR100281867B1 KR 100281867 B1 KR100281867 B1 KR 100281867B1 KR 1019970706430 A KR1019970706430 A KR 1019970706430A KR 19970706430 A KR19970706430 A KR 19970706430A KR 100281867 B1 KR100281867 B1 KR 100281867B1
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- auxindol
- present
- general formula
- bis
- Prior art date
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- 235000012239 silicon dioxide Nutrition 0.000 description 1
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Description
Claims (3)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP569396 | 1996-01-17 | ||
JP5693/1993 | 1996-01-17 | ||
JP1763696 | 1996-02-02 | ||
JP17636/1996 | 1996-02-02 | ||
PCT/JP1997/000066 WO1997026242A1 (fr) | 1996-01-17 | 1997-01-16 | Derives de 3-(bis-phenylmethylene substitue) oxindole |
Publications (2)
Publication Number | Publication Date |
---|---|
KR19980703022A KR19980703022A (ko) | 1998-09-05 |
KR100281867B1 true KR100281867B1 (ko) | 2001-02-15 |
Family
ID=26339674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970706430A KR100281867B1 (ko) | 1996-01-17 | 1997-01-16 | 3-(비스-치환페닐메틸렌)옥신돌유도체 |
Country Status (8)
Country | Link |
---|---|
US (1) | US5965600A (ko) |
EP (1) | EP0816338B1 (ko) |
KR (1) | KR100281867B1 (ko) |
AT (1) | ATE232515T1 (ko) |
AU (1) | AU702045B2 (ko) |
CA (1) | CA2214744C (ko) |
DE (1) | DE69718968T2 (ko) |
WO (1) | WO1997026242A1 (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
US6800287B2 (en) * | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
EP1149105B1 (en) | 1998-12-17 | 2008-02-27 | F. Hoffmann-La Roche Ag | 4,5-pyrazinoxindoles as protein kinase inhibitors |
ZA200206457B (en) * | 2000-02-18 | 2003-08-13 | Yeda Res & Dev | Oral, nasal and pulmonary dosage formulations of copolymer 1. |
US20020077278A1 (en) | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
CA2469393C (en) * | 2001-12-04 | 2010-05-25 | Teva Pharmaceutical Industries, Ltd. | Processes for the measurement of the potency of glatiramer acetate |
CN103274988B (zh) * | 2013-06-20 | 2016-04-13 | 河北大学 | 3-(氰基-p-硝基苯甲撑基)-2-吲哚酮衍生物及其合成方法和用途 |
CN108698991B (zh) | 2016-01-20 | 2022-08-23 | 凯莫森特里克斯股份有限公司 | 2-氧代吲哚化合物 |
CN108484474B (zh) * | 2018-04-04 | 2020-09-22 | 华南理工大学 | 具有聚集诱导发光性质的发光材料及其制备与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3413299A (en) * | 1963-07-11 | 1968-11-26 | Upjohn Co | 3', 3'-di-substituted[spiro-indoline-3, 2'-oxiran]-2 ones and derivatives |
GB1101794A (en) * | 1965-04-28 | 1968-01-31 | Upjohn Co | Improvements in or relating to new substituted oxindoles and the manufacture thereof |
US3428649A (en) * | 1968-01-23 | 1969-02-18 | Mcneilab Inc | Oxindole derivatives |
JPS60222415A (ja) * | 1984-04-20 | 1985-11-07 | Nippon Iyakuhin Kogyo Kk | 抗炎症剤 |
-
1997
- 1997-01-16 AT AT97900425T patent/ATE232515T1/de not_active IP Right Cessation
- 1997-01-16 CA CA002214744A patent/CA2214744C/en not_active Expired - Fee Related
- 1997-01-16 EP EP97900425A patent/EP0816338B1/en not_active Expired - Lifetime
- 1997-01-16 US US08/913,239 patent/US5965600A/en not_active Expired - Fee Related
- 1997-01-16 AU AU13987/97A patent/AU702045B2/en not_active Ceased
- 1997-01-16 DE DE69718968T patent/DE69718968T2/de not_active Expired - Fee Related
- 1997-01-16 WO PCT/JP1997/000066 patent/WO1997026242A1/ja active IP Right Grant
- 1997-01-16 KR KR1019970706430A patent/KR100281867B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2214744A1 (en) | 1997-07-24 |
CA2214744C (en) | 2002-12-24 |
DE69718968D1 (de) | 2003-03-20 |
AU702045B2 (en) | 1999-02-11 |
EP0816338B1 (en) | 2003-02-12 |
EP0816338A4 (en) | 2001-04-11 |
AU1398797A (en) | 1997-08-11 |
US5965600A (en) | 1999-10-12 |
ATE232515T1 (de) | 2003-02-15 |
DE69718968T2 (de) | 2003-10-09 |
KR19980703022A (ko) | 1998-09-05 |
WO1997026242A1 (fr) | 1997-07-24 |
EP0816338A1 (en) | 1998-01-07 |
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