JPS6075412A - Dentifrice composition - Google Patents

Abstract

PURPOSE:To provide a dentifrice composition having high shape-retainability even at a low viscosity, and improved stringiness, and extrudable easily from a pump-type container, by compounding a dentifrice with pyrogenetic ultrafine amorphous silica used as a binder. CONSTITUTION:Pyrogenetic ultrafine silica powder (having an average diameter of the primary particle of preferably 5-50mmu, especially 5-20mmu) is used as a binder, and is added to a dentifrice in an amount of preferably >=1%, especially 2-5% to obtain the objective dentifrice composition having a viscosity of <=600 poise (preferably 200-500 poise). The composition is suitable to be used by filling in a vertical pump-type container.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a dentifrice composition suitable for use in a vertical pump type container. Even when formed to a low viscosity below poise, the shape retention is good, and the stringiness is improved, and >I? The present invention relates to a dentifrice composition that is easily extruded from a dentifrice type container.

Conventionally, toothpaste has generally been stored in a tube, and its viscosity has usually been adjusted to 600% for ease of extrusion from the tube, ease of putting it on a toothbrush, shape retention, and threadability. It was formed to a size of ~900.1r.

However, recently, various vertical pump-type containers have been proposed that allow toothpaste to be taken out simply by pressing a suppressing operation part such as a button. Kaisho 55-3878
3. It is desired to store toothpaste in these pump-type containers and use it, but the viscosity IW of conventional toothpaste formulations is too high.
Not suitable for use in pump containers.

That is, according to the studies of the present inventors, a toothpaste for a vertical pump type container should have a viscosity of 600 boids or less, especially 200 to
It is preferably 500 poise, and despite having such a low viscosity, it has excellent shape retention without crumbling when placed on a toothbrush, and there is no stringiness. Excellent stringability is required, but conventional high-viscosity toothpaste formulations cannot be used due to their high viscosity, and the viscosity is simply reduced to 600 poise or less. However, it had poor shape retention, easily ran off when placed on a toothbrush, and had poor threadability.

For this reason, the present inventors conducted intensive research on a dentifrice composition suitable for use in a vertical pump-type container, and found that the dentifrice composition is easy to push out from the pump-type container.
It has been found that the above object can be effectively achieved by forming the composition to a viscosity of 0 poise or less, preferably 200 to 500 poise, and incorporating large-forming ultrafine powder amorphous silica.

That is, even if the present inventors tried to ensure the shape retention of toothpaste compositions using sodium carboxymethylcellulose, carragnan, etc., the shape retention was poor at low viscosity of 600 poise or less, and the shape retention was poor when placed on a toothbrush. However, by blending igneous ultrafine powder amorphous silica, the toothpaste composition can be made to have a molar mass of 600 or less. Even when formed with a low viscosity, it retains its shape well, does not lose its shape when taken out of the container and placed on a toothbrush, and is easy to knead as there is no threading phenomenon. It has been found that a toothpaste composition for use in a type container that retains its shape using large-forming ultrafine powder amorphous silica is effective, and the present invention has been developed based on this finding.

The present invention will be explained in detail below.

The dentifrice composition of the present invention uses an abrasive, a thickener, a binder, and if necessary, a surfactant, a sweetener, a fragrance, a preservative, various active ingredients, and other ingredients, and has a viscosity of 600 poise or less, Preferably, the viscosity is adjusted to 200 to 500 poise (the value measured at 25°C using a BH type viscometer), but in this case, in the present invention, the viscosity is The agent uses ultrafine powdered silica.

Here, as the large-forming ultrafine powder silica, one having an average diameter of secondary particles of 5 to 50 m[mu], particularly 5 to 20 m[mu] is suitably used. In addition, large-forming ultrafine powder amorphous silica has a specific surface area (BET method) of 100 to 450'/y, l,
The specific gravity is preferably 50 to 80'/1 (D 4 <7). As such igneous ultrafine powder amorphous silica,
Aerosil■ manufactured by Degussa, Ca manufactured by Capot
Examples include b-0-8ig[F].

The amount of the large-forming ultrafine powder amorphous silica is preferably at least 1 g (% by weight, the same hereinafter), particularly from 2 to 5 g, based on the entire composition.

In the present invention, in addition to the above-mentioned igneous ultrafine amorphous silica, other binders may be used as the binder, such as cellulose such as oxymethyl cellulose alkali metal salt, methyl cellulose, hydroxyethyl cellulose, carboxymethyl hydroxyethyl cellulose sodium, etc. derivatives, alkali metal alginates such as sodium alginate, propylene glycol alginate, gums such as caradanan, xanthan gum, gum tragacanth, gum karaya, gum arabic, etc. Synthetic binders such as ribinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, polyvinyl pyrrolyne, and inorganic binders such as aluminum silica gel and laponite.
A species or two or more species can be blended.

In this case, a dentifrice composition with good fluidity can be obtained by incorporating the thickening agent described below in a high concentration, particularly at least 10%, preferably 30 to 75% of the total composition. When preparing a highly fluid dentifrice composition with a high content of thickening agent, it is desirable to add carboxymethyl cellulose alkali metal salt such as carboxymethyl cellulose sodium in an amount of 0.1 to 2%, together with igneous ultrafine powder amorphous silica. In particular, it is preferable to mix 0.5 to 1.2% of the thickening agent, which can improve the stringiness of a dentifrice composition containing a high thickening agent content.

The dentifrice composition of the present invention contains an abrasive, a viscous agent, etc. as described above, and examples of these components include dicalcium phosphate dihydrate and dihydrate as an abrasive. Anhydrous, monocalcium phosphate, tertiary calcium phosphate, calcium carbonate, calcium pyrophosphate, calcium sulfate, titanium oxide, alumina, water-containing alumina,
Silica-based abrasives such as precipitated silica and anhydrous alkali metal silicate complexes, aluminum silicate, insoluble sodium metaphosphate, insoluble potassium metaphosphate, tertiary magnesium phosphate, magnesium carbonate, bentonite, zirconium silicate, synthetic resins, etc. These lK4
Alternatively, two or more types can be blended (the blending amount is usually 0 to 50%, especially 10 to 30%).

In addition, as a silica-based abrasive, 1, for example, JP-A-49-9
1994, JP 49-94.712, JP 50-64198, JP 50-65497
No. 1, JP-A-51-928695, JP-A-51-Sho.
Those described in Japanese Patent Publication No. 136841, Japanese Patent Publication No. 54-4919, etc. are used. A more specific example is +'-Zeoden@.

Precipitated silica, silica xerol, silica aerogel, etc. sold under the trademarks Zeo ■ and 5ident ■, which have primary particles of 500 μm or less and secondary particles of 1 to 30 μm, can be used. In this case, precipitated silica is particularly preferably used, S10. Content: 70% or more, preferably 90% or more, alkali/alkaline earth metal oxide content: O~5%%
Sin! The binding amount of oxides of metals such as aluminum, magnesium, and calcium is 0 to 10%, preferably 0 to 5%, and the attached moisture content (loss on drying) is 1 to 10%, with an average particle size of 0.5 to 30μ. , preferably 1 to 15
μ, specific surface area per 1f (BET method) 500 or less, more preferably 300 or less, refractive index 1.44 to 1.47
, a liquid absorption amount of 0.6 to 1.3 CC/r is preferably used. Specifically, Huber's Zeo 49 + Zeodent 113 *USA W
R, Grace's 5y1oid AL-1,63,
74,404, UK J, Croasfield & 5
Neosyl ET from ons, Deguss, Germany
Examples include 5ldent 3.20 manufactured by Company A.

In the present invention, these silica-based abrasives are effectively used.

In addition, examples of the thickening agent include Sorbit 5 glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylit, maltit, laftit, etc., and one or more of these can be used. It can be blended (the blended amount is usually 10 to 75 inches).

Furthermore, in the dentifrice composition of the present invention, water-soluble salts of higher alkyl sulfates whose alkyl group has 8 to 18 carbon atoms, such as sodium lauryl sulfate and sodium myristyl sulfate, hydrogenated coconut oil fatty acid monodaliseride monomers, etc. Water-soluble higher fatty acid monoglyceride monosulfate such as sodium sulfate, alkylaryl sulfonate such as sodium dodecylbenzenesulfonate, higher alkyl sulfonate, 1,2-dihydroxyzolo/? lower aliphatic aminocarboxylic acid esters such as sodium, potassium or ethanolamine salts of N-lauroyl, N-myristoyl or N-noglumitoyl dercosine;
? Anion activators such as substantially saturated higher aliphatic acylamides of phosphoric acid compounds, sucrose fatty acid esters in which the fatty acid group has 12 to 18 carbon atoms such as sucrose mono- and dilaurate, lactose fatty acid esters, lactitol fatty acid esters, Maltitol fatty acid ester, stearic acid monoglyceride, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monolaurate, polyoxyethylene (10120, 40, 60
, 80, 100 mol) hydrogenated castor oil, polymers of ethylene oxide and propylene oxide, polyoxyethylene polyoxypropylene monolauryl ester, etc. (7
)&IJ-+4L/7 oxide and one or more types of surfactants such as nonionic active agents such as condensation products of fatty acids, fatty alcohols, polyhydric alcohols, and polypropylene oxides, and amphoteric active agents such as betaine type and amino acid type. agent (compounding amount usually 0~7%, preferably 0.5~
5%), saccharin sodium, stevioside 1. Sweeteners (0 to 1, preferably 1%, preferably is 0.01-0.5%), ij! If necessary, preservatives such as p-hydroxymethylbenzoic acid, p-hydroxyethylbenzoic acid, p-hydroxyzologylpenzoic acid, p-hydroxybutylbenzoic acid, sodium benzoate, lower fatty acid monoglyceride, winter Green oil, spearmint oil, peppermint oil, satsafras oil, cloves,
Fragrances such as eucalyptus oil, gelatin, peptone, arginine hydrochloride, albumin.

Brighteners such as casein and titanium dioxide, silicone, pigments, and other ingredients may be added.

In addition, the dentifrice composition of the present invention includes enzymes such as allantoins, epsilonamitsukagulonic acid, tranexamic acid, dextranase, amylase, protease, mutanase, lysozyme, lytic enzyme, and Lytec enzyme, sodium monofluorophosphate, Alka IJ Gold M monofluorophosphate such as potassium monofluorophosphate, fluorides such as sodium fluoride, ammonium fluoride, and stannous fluoride, chlorhexinone salts, dihydrocholesterol, glycyrrhetate, glycyrrhetinic acid, glycerophosphate , chlorophyll, calopeptide,
One or more active ingredients such as water-soluble inorganic phosphoric acid compounds, vitamins, anti-tartar agents, antibacterial agents, and plaque inhibitors may be blended.

The dentifrice composition according to the present invention uses large-forming ultrafine powder amorphous silica and the above-mentioned appropriate ingredients, and is prepared to have a viscosity of 600 poise or less, and has good extrudability. Moreover, despite its low viscosity, it has good shape retention and improved spinnability.
It can be used by being housed in a vertical pump-type container of the type in which the contents are pressed and pushed out from the contents outlet by pushing a suppressing operation part such as a tongue.

Oh, as for such a pump-type container,
34641. Utility model 55-38783, 1987-4
6572. 1987-100378% 1987-1
21677, Utility Model 57-44041, Utility Model 57-7
4168. Unpublished 1.64079, 1.64079, JP 57-
68367, JP-A No. 57-68368, etc., and the dentifrice composition of the present invention can be suitably used by filling these containers.

Next, experimental examples will be shown to specifically explain the effects of the present invention.

[Experiment example]

Toothpaste compositions having the formulations Nos. 1 to 7 shown in Table 1 were prepared.

Next, the viscosity of these toothpastes was measured (25°Q) using a BI (type viscometer), and these toothpastes were
It was filled into the container described in JP 4-34641 and evaluated for shape retention, stringiness, and ease of extrusion when extruded from the container. The results are shown in Table 2.

2 Table 2 However, the evaluation criteria are as follows.

Evaluation criteria Shape retention ○: The toothbrush rides well and the mold does not come loose.

△: The shape is slightly distorted.

×: Easily washed away from a toothbrush.

Stringability ○: When placed on a toothbrush, it does not become stringy and has good threadability.

△: When placed on a toothbrush, stringiness is less than 5 ctn.

×: When placed on a toothbrush, the stringiness is 5 cm or more. Up.

○: Toothpaste comes out of the container with low resistance.

Δ: Some resistance is felt when pushing out from the container.

×: Some resistance was felt when pushing out from the container.

Difficult to push out.

The results in Table 2 show that the dentifrice composition containing large-forming ultrafine powder amorphous silica has good shape retention despite its low viscosity, has good stringability, and is easy to extrude from the container. It is found that it is a thing.

Examples are shown below.

[Example 1] Precipitated silica 17% Propylene glycol 3 Glycerin 25 Nruvit 20 Gelatin 0.3 Caldexymethyl cellulose 1 Sodium 6 Sodium lauryl sulfate 1.5 N-lauroyl sarcosy 0.3 Sodium natesaccharin 0.1 Paraben 0.1 Fragrance 1 Total 1 00.0% Viscosity 450 poise [Example 2] Precipitated silica 17% Polyethylene glycol 4 Glycerin 25 Sorbit 23 Gelatin 0.3 Caradanan 0.5 Large-sized ultrafine powder amorphous silica 2 (Aerosie) Lauryl Sodium sulfate 1.5 Sodium saccharin 0.1 Lapen 0.1 Flavor 1 Total 100.0% Viscosity 500 voise [Example 3] Precipitated silica 15 Polyethylene glycol 4 Glycerin 20 Sorbit 22 Gelatin 0.5 Lauryl Sodium sulfate 1.5 N-2 uroyl sarcosi 0.3 Sodium natesaccharin 0.1 Chlorhexidine hydrochloride 0.01 Noyarapen 0.1 Fragrance 1 Total 100.0% Viscosity 530 poise [Example 4] Dibasic calcium phosphate 30% Polyethylene glycol 3 Nrubit 35 Sodium lauryl sulfate 1.8 Sodium saccharin 0.1 Paraben o, i l・9 Fragrance 1 Purified ice Remaining total ioo, ochi Viscosity 600 poise [Example 5] Calcium carbonate 25% Zoropylene glycol 2 .5 Glycerin 25 Sorbitol E0 Sodium lauryl sulfate 1.5 Satucalin sodium 0.1 Tatarhexidine hydrochloride 0.01 Paraben 0-1 Fragrance 1 Purified ice Remaining total 100.0% Viscosity 580 Voids 0 [Example] 6] Aluminum hydroxide 35 Thipropylene glycol 3 Nlupitz, To 30 Gelatin 0.5 Sodium alginate 1 Sodium lauryl sulfate 1.2 Diethanol laurate 0.5 Sodium amidosaccharin 0.1 Sodium monofluorophosphate 0.76 Dextonase 2000 u/ f'paraben 0.1 Fragrance 1 Total 100.0% Viscosity 590 poise [Example 7] Insoluble sodium metaphosphate 35 Thipropylene glycol 3 Glycerin 25 Nrubit 23 Caldexymethyl cellulose 1 Sodium lauryl sulfate 1.5 N-Lauroyl del Cosinate 0.3 Satucalin sodium 0.1 Chlorhexidine hydrochloride 0.01 Paraben 0.1 Fragrance 1 Total 100.0% Viscosity 550 poise [Example 8] Precipitated silica 10% Propylene glycol 3 Glycerin 2° Solpit 1° Gelatin 0.5 Carragnan 1 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Tranexamic acid 0.01 Paraben 0.1 Fragrance 1 Total 1 00.0 Viscosity 320 poise The toothpastes of Examples 1 to 8 were: All of them have good shape retention, stringability, and ease of extrusion.
Even when it was stored in the container described in Publication No. 1, it was possible to extrude it smoothly.

Applicant Lion Corporation Agent: Patent Attorney Takashi Kojima 3 =71-

Claims (1)

[Scope of Claims] 1. A toothpaste composition characterized by having a viscosity of 600 poise or less and containing igneous ultrafine amorphous silica. 2. The dentifrice composition according to claim 1, which has a viscosity of 200 to 500 poise. 3. The dentifrice composition according to claim 1 or 2, wherein the amount of large-forming ultrafine amorphous silica is 1% by weight or more of the total amount. 4 Vertical d? It was housed in a pump-type container! Scope of Claims No. 1
The dentifrice composition according to any one of items 1 to 3.