JPS59139308A - Cosmetic - Google Patents

Abstract

PURPOSE:A cosmetic, containing soluble elastin and/or the soluble elastin and a humectant comonent and/or a physiologically active compnent, capable of activiting the metabolism of the skin, increasing resilience of the skin, and having improved effect on the protection of the skin and retention of water. CONSTITUTION:A cosmetic containing (A) soluble elastin and/or the soluble elastin and (B) a humectant component, e.g. an amino acid, NMF component, peptide or polysaccharide, and/or a physiologically active component, e.g. a vitamin, enzyme, crude drug extract or nucleic acid related substance. The component (A) is supplied in the form of an aqueous solution containing 5-30wt% solid component, and the amount thereof to be incorporated is 0.0001wt% or more as the solid component. The amounts of the humectant and the physiologically active component are respectively 0.01wt% or more and 0.0001wt% or more. The above-mentioned cosmetic is used in the form of toilet water, various creams, milky lotion, pack or cleaning cosmetic, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a novel cosmetic, which aims to activate the regenerating parts of the skin, increase the elasticity of the skin,
The object of the present invention is to provide a cosmetic that has excellent effects on skin protection and moisture retention.

When skin is analyzed histologically, collagen fibers and elastic fibers form a network in the dermis, which is said to provide the skin with elasticity and tensile strength. In recent years, collagen and elastin obtained by making these fibers obtained from animals soluble through chemical treatment, or by extracting soluble fiber molecules from these fibers, have been incorporated into cosmetics as skin protection and moisturizing agents. Ta. Among these, elastin has unique chemical structures such as the random orientation of single-molecule crosslinks and the presence of hydrophobic bona V) in the molecule due to the large number of hydrophobic amino acids [
Koji Okamoto et al., Proteins/Nucleic Acids/Enzymes, 24.1471-1
4B6 (1979):I, it has the effect of increasing the elasticity of the skin. However, when elastin is added alone to cosmetics, its expected effects are still not sufficient, and increasing the amount added may have a negative impact on the stability of cosmetics, increase costs, etc. It had drawbacks.

Therefore, the present inventors took this issue into consideration and conducted extensive research on combinations that synergistically enhance the skin-creating effects of soluble elastin and/or solubilized elastin, and as a result, they found that they can increase skin elasticity and improve skin protection. The present invention has been completed in order to obtain a cosmetic having an excellent effect on water retention.

That is, the present invention is a cosmetic material containing soluble elastin and/or solubilized elastin, and a moisturizing component and/or a physiologically active component as essential components.

The soluble elastin used in the present invention is a soluble fiber molecule extracted from elastic fibers present in the dermis of the skin,
Solubilized elastin is the elastic fiber made soluble through chemical treatment. ◇These soluble elastin and solubilized elastin are supplied as an aqueous solution containing 5 to 30% by weight as a solid component, and their use The effective amount is o,oooiim% or more as a solid component.

The moisturizing ingredients used in the present invention include amino acids, IMF components, peptides, polysaccharides, etc., and can be used singly or in combination of two or more, and the amount used is 0.01 weight or more. It is valid.

Next, physiologically active ingredients include vitamins, enzymes, crude drug extracts, nucleic acid-related substances, etc., and can be used singly or in combination of two or more, and the amount used is 0.0
It is effective at 0.001% by weight or more.

Examples of amino acids include heptaphosphorus, glycine, asparagine, aspartic acid, lysine, arginine, threonine, cysteine, and derivatives thereof.

NMF components include lactic acid, PGA, citric acid, succinic acid, urea, etc., and their sodium salts, potassium salts,
Triethanolamine salt.

Examples include salts such as arginine salts, gin salts, histidine salts, ornithine salts, and oxylysine salts, and derivatives thereof.

Examples of peptides include soluble collagen, gelatin, etc., and derivatives thereof.

Examples of the multi-Ws include sucrose, maltose, cellulose, starch-based carrageenan, chondroitin sulfate, hyaluronic acid, salts thereof, and derivatives thereof.

Vitamins include vitamin B2, vitamin B8, vitamin "Ill'" vitamin 0, vitamin E,
Examples include vitamin F, vitamin H, etc., and derivatives thereof.

Enzymes include proteases such as papain, trypsin, sugar-containing hepsin, and bioplase, lysozyme chloride, and alkaline phosphatase.

Examples of crude drug extracts include those having an anti-inflammatory effect, such as Shikon, Toki, Ginseng, Tokuyaku, Yozai, Rhihuang, Arnica, and Chamomile.

Nucleic acid-related substances include DNA, RNA, nucleotides,
Examples include nucleosides, AMP, salts thereof, and derivatives thereof.

The cosmetic according to the present invention is a cosmetic containing the above-mentioned soluble elastin and/or solubilized elastin, and a moisturizing ingredient and/or a physiologically active ingredient as essential ingredients, and is a soft lotion. - Toners such as astringent lotions and cleaning lotions 1 Creams such as emollient creams, pine surge creams, cleansing creams, makeup creams, emollient emulsions, moisturizing emulsions, Milky Roshi Sho, nourishing emulsions, cleansing emulsions, etc. Main products include emulsion 111, packs such as jelly packs, paste bags, and powder bags, and facial cleansers.

Next, the present invention will be further explained by giving examples.

These do not define the present invention in any way. Hereinafter, % represents weight %.

[Example 1] Cream (formulation) 11) Stearic acid 1.0 (
2) Stearyl alcohol 4D (3)
Glyceryl monostearate 30(4)
Hydrogenated oil ZO (5) Liquid paraffin 10.0 (6) Safflower oil 2.0 (7) Sorbitan sesquioleate 1.0 (8) Fragrance
0.5(9) Sodium hydroxide 0.05αQ Carboxyvinyl polymer D, 1αυ Solubilized elastin (1
0% aqueous solution] 1.0 02 Shihun extract 1. Oa3
Preservative 01'1J4
purified water
Remaining amount (manufacturing method) Heat and dissolve A(1) to (8) (70°C).

Heat and dissolve B(9), 111Sα3, α4 (70°C)
do.

Add B to OA to emulsify, add (lit and σ), cool, and obtain cream.

(Prescription) % (1)
Stearic acid 0.5 (2;
Setanol t5 (3) Glyceryl monostearate 2.0 (4) Liquid paraffin 5.0 (5) Avocado oil 10 (6) Sorbitan sesquioleate 0.5 (7) Fragrance
0.2(81L3-butylene glycol 5.0(9) Sodium hydroxide
0.02Ql d/- Sodium pyrrolidonecarboxylate
0. 2 (11
) ATP Su) IJ '5' Mu0-10
Soluble elastin (10% aqueous solution) 1.Oa3 Preservative 0.184) Purified water Remaining amount (manufacturing method) A Dissolve (1) to (7) by heating (70°C).

Table 2 Table 3 As is clear from the results in Tables 1 to 3, by using the cosmetics of the present invention, the skin becomes elastic and firm, and the skin feels moisturized. The effect of reducing the appearance of fine wrinkles was confirmed with a high efficacy rate.

that's all Applicant: Kobayashi Kose Co., Ltd.

Claims (1)

[Scope of Claims] [11] A cosmetic comprising 11 soluble elastin and/or solubilized elastin and 1 moisturizing ingredient and/or physiologically active ingredient as essential ingredients. (2) The cosmetic according to claim 1, in which the moisturizing component comprises one or a combination of two or more of amino acids, HMF components, peptides, and polysaccharides. (3) The cosmetic according to claim 1, wherein the physiologically active ingredient is one or a combination of two or more of vitamins, enzymes, crude drug extracts, and nucleic acid-related substances.