JPS58159405A - Ascorbic acid-containing composition - Google Patents
Ascorbic acid-containing compositionInfo
- Publication number
- JPS58159405A JPS58159405A JP57042450A JP4245082A JPS58159405A JP S58159405 A JPS58159405 A JP S58159405A JP 57042450 A JP57042450 A JP 57042450A JP 4245082 A JP4245082 A JP 4245082A JP S58159405 A JPS58159405 A JP S58159405A
- Authority
- JP
- Japan
- Prior art keywords
- ascorbic acid
- extract
- composition
- containing composition
- yokuinin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
Description
【発明の詳細な説明】
本発明はアスコルビン酸含有組成物に関し、更に詳細に
は、アスコルビン酸又はその誘導体を含有する組成物中
にヨクイニン抽出物全配合した、アスコルビン酸を安定
化することができると共に潰れた皮膚美白効果を有し、
しかも安全性の高いアスコルビン酸含有組成物に関する
。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an ascorbic acid-containing composition, and more particularly, the present invention relates to an ascorbic acid-containing composition, and more particularly, a composition containing ascorbic acid or a derivative thereof that is capable of stabilizing ascorbic acid. It also has a whitening effect on crushed skin,
Moreover, the present invention relates to a highly safe ascorbic acid-containing composition.
アスコルビン酸は、種々の飲料、化粧料等に用いられ、
皮膚美白剤の１つである。しかし、アスコルビン酸ハ酸
化されやすいので、従来、これを配合し、組成物とする
に際して抗酸化剤もしくは還元剤を添加したり、高級脂
肪酸、リン酸のエステル体としたり、窒素雰囲気下で製
造を行なうなど種々の方法が採用されている。しかしな
がら、これらの方法は未だ充分満足のゆくものではなか
った。Ascorbic acid is used in various beverages, cosmetics, etc.
It is one of the skin whitening agents. However, ascorbic acid is easily oxidized, so conventionally it has been blended into compositions by adding antioxidants or reducing agents, making it into esters of higher fatty acids or phosphoric acid, or manufacturing it under a nitrogen atmosphere. Various methods have been adopted. However, these methods have not yet been fully satisfactory.
本発明者は、アスコルビン酸又はその誘導体の安定化方
法に関し、種々研究をおこなっていたところ、アスコル
ビン酸とハトムギの種実であるヨクイニン（見、亘仁、
英名：ｃｏ１ｘ ｓθθｄ）の抽出物を組成物中に配合
すればアスコルビン酸が、安定に保たれることを見出し
、本発明を完成した。The present inventor was conducting various studies on methods for stabilizing ascorbic acid or its derivatives, and discovered that ascorbic acid and coix seed yokuinin (Mi, Watahito,
The inventors have discovered that ascorbic acid can be kept stable by incorporating an extract of the English name: co1x sθθd) into a composition, and have completed the present invention.
すなわち、本発明はアスコルビン酸又はその誘導体を含
有する組成物において、ヨクイニン抽出物を配合したこ
とを特徴とするアスコルビン酸含有組成物を提供するも
のである。That is, the present invention provides an ascorbic acid-containing composition characterized in that it contains an extract of Ikuinin in the composition containing ascorbic acid or a derivative thereof.
本発明で用いるヨクイニン抽出物は、次に述べるような
種々の抽出法で得ることができ、これをそのままで、又
は濃縮し、おるいは水もしくはアルコールで希釈もしく
は溶解して用いることができる。The extract used in the present invention can be obtained by various extraction methods as described below, and can be used as it is, or after being concentrated, or diluted or dissolved with water or alcohol.
（Ａ） ■主呼たは乾燥ヨクイニンを水またはアルコ
ール、アセトンなどの親水性有機溶剤、または含水親水
性有機溶剤で抽出し、抽出液を沖過してＰ液を採取する
。必要に応じて溶剤を除去濃縮する、。(A) ① Extract the main or dried yokuinin with water, alcohol, a hydrophilic organic solvent such as acetone, or a water-containing hydrophilic organic solvent, and collect the P solution by filtering the extract. Concentrate, removing solvent if necessary.
■上記抽出液もしくハ濃縮液もしくは濃縮残留物を水で
抽出し、ヂ過によって不溶部を除去して可溶部を採取す
る。必要に応じて濃縮する。(2) Extract the above extract or (c) concentrate or concentrated residue with water, remove the insoluble part by filtration, and collect the soluble part. Concentrate if necessary.
■ヨクイニン全エタノール等のアルコール−３−′
類で浸出し、この浸液に不溶性または難溶性の油脂、例
えば椿油、ヒマシ油等を加え、さらに水を加えて攪拌し
、静置して２層に分離したのち、アルコール類水溶液の
層を分取する。■Yokuinin is leached with alcohol-3-' such as total ethanol, and insoluble or poorly soluble fats and oils, such as camellia oil and castor oil, are added to this immersion liquid, water is added, stirred, and left to form a layer. After separation, the aqueous alcohol solution layer is separated.
（Ｂ） 上記■〜■の方法によって得られた有効成分
全含有する水、アルコール、アルコール水溶液等を噴霧
乾燥し、粉末化してヨクイニン抽出物を得る。(B) The water, alcohol, alcohol aqueous solution, etc. containing all of the active ingredients obtained by the above-mentioned methods 1 to 2 are spray-dried and powdered to obtain an extract of Yokuinin.
■〜■の抽出は冷浸又は温浸の何れによってもなし得る
が、通常４０〜６０℃の温度で数時間ないし数日行うの
が好ましい。The extractions (1) to (2) can be carried out by either cold soaking or hot soaking, but it is usually preferable to carry out the extraction at a temperature of 40 to 60° C. for several hours to several days.
上に述べたヨクイニン有効成分抽出法または乾燥エキス
製造方法は一例であって本発明において用いる抽出物は
上記以外のいかなる ４一
方法によるものであってもよい。The above-mentioned method for extracting the active ingredients of Yokuinin or the method for producing a dry extract is just one example, and the extract used in the present invention may be obtained by any method other than the above.
成上の方法により、ヨクイニン１３ＫｐからｌＫ９の割
合でヨクイニン抽出物が得られる。According to the method described above, an extract of Yokuinin is obtained at a ratio of 13Kp to 1K9 of Yokuinin.
また、本発明では、アスコルビン酸のほか、その誘導体
も使用することができ、誘導体としては、例えばアスコ
ルビン酸−３−リン酸エステル、アスコルビン酸−２−
ｍｅエステル、アスコルビン酸ステアリン酸エステル、
アスコルビン酸バルミチン酸エステル、アスコルビン酸
シバルミチン酸エステルなどが挙げられる。Further, in the present invention, in addition to ascorbic acid, derivatives thereof can also be used, and examples of the derivatives include ascorbic acid-3-phosphate, ascorbic acid-2-
me ester, ascorbic acid stearate,
Examples include ascorbic acid balmitate and ascorbic acid balmitate.
本発明組成物において、アスコルビン酸又はその誘導体
は０．０５〜１０重量％（以下チで示す）、好ましくは
０．１〜５チ配合するのがよい。また、ヨクイニン抽出
物は０．１〜２０チ、好ましくは０．５〜１０チ配合す
るのがよい。更にアスコルビン酸又はその誘導体とヨク
イニン抽出物の相対配合比は、１対１ないし１対１００
、好ましくは１対５ないし１対５０であるのがよい。In the composition of the present invention, ascorbic acid or a derivative thereof is preferably blended in an amount of 0.05 to 10% by weight (hereinafter referred to as H), preferably 0.1 to 5% by weight. In addition, it is preferable to mix 0.1 to 20 tchi, preferably 0.5 to 10 tchi, of the Ikuinin extract. Furthermore, the relative blending ratio of ascorbic acid or its derivative and Yokuinin extract is 1:1 to 1:100.
, preferably 1:5 to 1:50.
本発明組成物は、上記量のアスコルビン酸又はその誘導
体とヨクイニン抽出物を配合するほか常法に従い公知の
組成物成分を配合することができ、その形態は、乳液、
クリーム、ローンヨン、バック等の皮膚化粧料：清涼飲
料水１食品添加物等の食品及びその他石鹸、洗顔剤、歯
磨等とすることができる。In the composition of the present invention, in addition to blending the above amount of ascorbic acid or a derivative thereof and an extract of Yokuinin, other known composition components can be blended according to a conventional method.
Skin cosmetics such as creams, lotions, and bags: soft drinks, foods such as food additives, and other products such as soaps, face washes, toothpastes, etc.
成上の公知組成物成分としては、皮膚化粧料の場合はホ
ルモン類、アスコルビン酸を除くビタミン類、生薬及び
臓器抽出物等が、食品では、糖質、脂質、蛋白質、ミネ
ラル類。In the case of skin cosmetics, known composition components include hormones, vitamins other than ascorbic acid, herbal medicines, and organ extracts, and in the case of foods, carbohydrates, lipids, proteins, and minerals.
アスコルビン酸を除くビタミン類等力、洗顔剤では、殺
菌剤、顔料、生薬及び臓器抽出物等が挙げられる。Examples of face washes include vitamins other than ascorbic acid, disinfectants, pigments, herbal medicines, and organ extracts.
斯くして得られた本発明組成物は、経口的に用いた場合
、優れた美顔効果を奏することが知られているヨクイニ
ン抽出物と、皮膚美白剤の１つであるアスコルビン酸又
はその誘導体を配合したものであるため、相加的に優れ
た美肌効果を示し、また、ヨクイニン抽出物が生薬であ
るため、その安全性も非常に高いものである。The thus-obtained composition of the present invention contains an extract of Yokuinin, which is known to have excellent facial beautification effects when used orally, and ascorbic acid, which is one of the skin whitening agents, or a derivative thereof. Since it is a blended product, it exhibits an excellent additive effect on beautifying the skin, and since the extract is a herbal medicine, its safety is also extremely high.
以下に実施例をもってさらに詳細に説明するが、本発明
はこれらの実施例に限定されるものではない。なお、ヨ
クイニン抽出物の製造例を参考例として示す。The present invention will be explained in more detail with reference to examples below, but the present invention is not limited to these examples. In addition, an example of manufacturing a yokuinin extract is shown as a reference example.
７−
参考例１゜
皮を取り去ったヨクイニン１３に９に水１３０Ｋｇ−金
加え、２４時時間待（約４０℃）浸出し、浸液全噴霧乾
燥して約Ｉ Ｋｐのヨクイニン抽出粉末を得た。7- Reference Example 1゜ Add 130 kg of water to 9 and remove the skin from Yokuinin 13, infuse for 24 hours (approximately 40°C), and spray dry all of the soaked liquid to obtain Yokuinin extracted powder of approximately I Kp. .
この抽出粉末は、帯幅白色の粉末で、水分（常圧乾燥法
にて測定）は４〜７チ、蛋白質１〜３チ、脂質０．１〜
０．２％、灰分０．２〜０．８％。This extracted powder is a white-banded powder with a moisture content (measured by normal pressure drying method) of 4 to 7 t, protein of 1 to 3 t, and lipid of 0.1 to
0.2%, ash 0.2-0.8%.
糖質 ９０〜９４チを含有する。しかし、用いるヨクイ
ニンの原料により、これら組成比は、異なる場合がある
。Contains 90-94 grams of carbohydrates. However, these composition ratios may differ depending on the raw material of Yokuinin used.
実施例１゜
アスコルビン酸及びこれとヨクイニン抽出物を含有する
水溶液（ｐＨ６，０、０，１Ｍ ！Ｊン酸緩衝液）を調
製し、該水溶液中のアスコルビン ８−
酸含量を測定することにより経時的なアスコルビン酸含
量率の変化を調べた。この結果を第１表に示す。なお、
アスコルビン酸含ｔの測定は、２，６−シクロルフエノ
ールインドフエノールが酸性水溶液中でアスコルビン酸
により還元されることを利用したインドフェノール滴定
法によりおこなった。Example 1 An aqueous solution (pH 6, 0, 0, 1 M! J acid buffer) containing ascorbic acid and an extract of Ikuinin was prepared, and the content of ascorbic 8-acid in the aqueous solution was measured over time. The changes in ascorbic acid content were investigated. The results are shown in Table 1. In addition,
The ascorbic acid content was measured by an indophenol titration method utilizing the fact that 2,6-cyclophenol indophenol is reduced by ascorbic acid in an acidic aqueous solution.
第 １ 表
第１表から明らかなように１ ヨクイニン抽出物を配
合した組成物は、これらを配合しないものに比較して著
しくアスコルビン酸を安定化させることができる。Table 1 As is clear from Table 1, the composition containing the extract of 1. Yokuinin can significantly stabilize ascorbic acid compared to the composition containing no extract.
実施例２゜
栄養クリーム
■ワセリン １０．０重量
部■ラノリン ５．０■イソ
プロピル・ミリステート５．０
■ステアリルアルコール ５．０■流動パラ
フイン ５．０■安息香酸プロピルエ
ステ＃ ０．１■ソルビタンモノステアレート
２．０■グリセロールモノステアＶ−）２
．０■ポリオキシエチレンツルとタンモノステアＶ−）
２．０［相］安息香酸メチルエステル ０．
１０ヨクイニン抽出物（参考例１．で得たもの）２．０
０アスコルビン酸 ０．２０水
バランス計
１００
［相］〜＠’ｉ７０℃で加温して、おだやかにかき１ぜ
ながら、同じく７０℃に加温した）垂を徐々に添加し乳
化する。次いでこれを冷却し、製品とする。Example 2゜Nutritional cream ■ Vaseline 10.0 parts by weight ■ Lanolin 5.0 ■ Isopropyl myristate 5.0 ■ Stearyl alcohol 5.0 ■ Liquid paraffin 5.0 ■ Propyl ester benzoate # 0.1 ■ Sorbitan mono Stearate 2.0■Glycerol monostear V-)2
．． 0■Polyoxyethylene vine and tongue monostair V-)
2.0 [Phase] Benzoic acid methyl ester 0.
10 Yokuinin extract (obtained in Reference Example 1) 2.0
0 ascorbic acid 0.20 water
balance meter
100 [Phase]~@'iHeat at 70°C, and while stirring gently, gradually add the taro (also heated to 70°C) to emulsify. Next, this is cooled and used as a product.
実施例３゜
清涼飲料水
■リンゴ酢 １０．０重量部■
クエン酸 ５．０■ビタミンＢ、
０．０５■ Ｉ Ｂ、
０．０５１１−
■ビタミンＢ、 ０．２■ ＃
Ｂ、（ＬＯ５
■アスコルビン酸 ０．２■
カフエイン ０．５■グラニユー
糖 １３０．０［相］蜂 蜜
２０・０（リエタノール
１０．００ヨクイニ唯出物（参考例１．で得た
もの） ２０．００ドリンク・フレーバー
４．５（やミネラル會ウォーター バ
ランス計 １０００
■〜ｑヤを充分攪拌溶解後、涙過し、ボトルに詰め、殺
菌後製品とする。Example 3゜Soft drink ■Apple cider vinegar 10.0 parts by weight■
Citric acid 5.0■ Vitamin B,
0.05 ■ I B,
0.0511- ■Vitamin B, 0.2■ #
B, (LO5 ■Ascorbic acid 0.2■
Caffeine 0.5 ■ Granulated sugar 130.0 [Phase] Honey
20.0 (reethanol
10.00 Yokuini Extract (obtained in Reference Example 1) 20.00 Drink Flavor
4.5 (Ya Mineral Water Balance Meter 1000) After thoroughly stirring and dissolving the mixture, strain it, bottle it, and use it as a sterilized product.
以上 １２−that's all 12-
Claims (1)
において、ヨクイニン抽出物を配合したこと’ｒ％徴と
するアスコルビン酸含有組成物。 ２、皮膚化粧料である特許請求の範囲第１項記載のアス
コルビン酸含有組成物 ３、 清涼飲料水である特許請求の範囲第１項記載のア
スコルビン酸含有組成物 ４、 ヨクイニン抽出物が、ヨクイニ／を水若しくは親
水性有機溶媒又はこれらの混合溶媒で抽出することによ
り得られたものである特許請求の範囲第１項記載のアス
コルビン酸含有組成物。、[Scope of Claims] 1. An ascorbic acid-containing composition characterized in that a composition containing all ascorbic acid or its derivatives contains an extract of Yokuinin. 2. The ascorbic acid-containing composition according to claim 1, which is a skin cosmetic; 3: The ascorbic acid-containing composition 4, which is a soft drink; The ascorbic acid-containing composition 4, which is a soft drink; The ascorbic acid-containing composition according to claim 1, which is obtained by extracting / with water, a hydrophilic organic solvent, or a mixed solvent thereof. ,
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57042450A JPS58159405A (en) | 1982-03-17 | 1982-03-17 | Ascorbic acid-containing composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57042450A JPS58159405A (en) | 1982-03-17 | 1982-03-17 | Ascorbic acid-containing composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS58159405A true JPS58159405A (en) | 1983-09-21 |
Family
ID=12636404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57042450A Pending JPS58159405A (en) | 1982-03-17 | 1982-03-17 | Ascorbic acid-containing composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58159405A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6078908A (en) * | 1983-10-05 | 1985-05-04 | Tokyo Yushi Kogyo Kk | Lipid for skin cosmetic |
| JPS6127910A (en) * | 1984-07-19 | 1986-02-07 | Kao Corp | Cosmetic |
| JPS6256410A (en) * | 1985-09-06 | 1987-03-12 | Soken:Kk | Production of cosmetic and bathing agent from aloe, mugwort and adlay |
| JP2004091351A (en) * | 2002-08-30 | 2004-03-25 | Kose Corp | Skin preparation for external use |
| CN102885366A (en) * | 2011-07-20 | 2013-01-23 | 江西食方食坊中药食品有限公司 | Anticancer health-care coix seed beverage and preparation method thereof |
-
1982
- 1982-03-17 JP JP57042450A patent/JPS58159405A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6078908A (en) * | 1983-10-05 | 1985-05-04 | Tokyo Yushi Kogyo Kk | Lipid for skin cosmetic |
| JPS6127910A (en) * | 1984-07-19 | 1986-02-07 | Kao Corp | Cosmetic |
| JPS6256410A (en) * | 1985-09-06 | 1987-03-12 | Soken:Kk | Production of cosmetic and bathing agent from aloe, mugwort and adlay |
| JP2004091351A (en) * | 2002-08-30 | 2004-03-25 | Kose Corp | Skin preparation for external use |
| CN102885366A (en) * | 2011-07-20 | 2013-01-23 | 江西食方食坊中药食品有限公司 | Anticancer health-care coix seed beverage and preparation method thereof |
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